MCID: RNL005
MIFTS: 21

Renal Wilms' Tumor

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Renal Wilms' Tumor

MalaCards integrated aliases for Renal Wilms' Tumor:

Name: Renal Wilms' Tumor 12 15
Nonanaplastic Renal Wilm's Tumour 12
Nonanaplastic Renal Wilm's Tumor 12
Nonanaplastic Renal Wilms Tumor 12
Renal Wilms' Tumour 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5176
NCIt 49 C6951
UMLS 71 C1335062

Summaries for Renal Wilms' Tumor

MalaCards based summary : Renal Wilms' Tumor, also known as nonanaplastic renal wilm's tumour, is related to wilms tumor 5 and mixed cell type kidney wilms' tumor. An important gene associated with Renal Wilms' Tumor is TUT7 (Terminal Uridylyl Transferase 7). Affiliated tissues include kidney, testis and cervix.

Related Diseases for Renal Wilms' Tumor

Diseases related to Renal Wilms' Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 wilms tumor 5 11.7
2 mixed cell type kidney wilms' tumor 11.4
3 blastema predominant kidney wilms' tumor 11.4
4 epithelial predominant wilms' tumor 11.4
5 stromal predominant kidney wilms' tumor 11.4
6 wilms tumor 1 9.9
7 wilms tumor predisposition 9.5 WT1 DIS3L2
8 perlman syndrome 9.1 TUT7 TUT4 TUT1 DIS3L2

Graphical network of the top 20 diseases related to Renal Wilms' Tumor:



Diseases related to Renal Wilms' Tumor

Symptoms & Phenotypes for Renal Wilms' Tumor

Drugs & Therapeutics for Renal Wilms' Tumor

Search Clinical Trials , NIH Clinical Center for Renal Wilms' Tumor

Genetic Tests for Renal Wilms' Tumor

Anatomical Context for Renal Wilms' Tumor

MalaCards organs/tissues related to Renal Wilms' Tumor:

40
Kidney, Testis, Cervix

Publications for Renal Wilms' Tumor

Articles related to Renal Wilms' Tumor:

(show all 19)
# Title Authors PMID Year
1
Wilms' Tumor and Benign Renal Tumor Combined With Hypospadias and Incomplete Orchiocatabasis Appearing Simultaneously in a 10 Months Old Boy. 61
31134609 2020
2
A Case of Primary Paratesticular Wilms Tumor in an Undescended Testis. 61
30610907 2019
3
Primary Extra-renal Wilms' Tumor in Urinary Bladder: Rare Presentation of a Common Pediatric Malignancy. 61
31142414 2019
4
Post therapy Wilms tumour or ectopic immature renal tissue: A pathologist's diagnostic dilemma. 61
30971552 2019
5
A retroperitoneal extra-renal wilms' tumour: A case report. 61
28256497 2017
6
Extra-Renal Wilms' Tumor: A Rare Diagnosis. 61
26064807 2015
7
Urinary exosomal Wilms' tumor-1 as a potential biomarker for podocyte injury. 61
23761678 2013
8
Bilateral botryoid nephroblastoma: a rare cause of renal failure. 61
22962373 2012
9
Extra-renal Wilms' tumour--is it different? 61
16520955 2006
10
Wilms' tumor of the cervix: a case report and review of the literature. 61
10620450 2000
11
Quantitative analysis of ultrasonic B-mode images. 61
10604798 1999
12
Brachytherapy for residual intra-renal Wilms' tumor. 61
9078328 1997
13
Interleukin-6 production in primary histoculture by normal human kidney and renal tumor tissues. 61
9066639 1997
14
Extrarenal Wilms' tumor: an ultrastructural and immunoelectron microscopic case report. 61
8882361 1996
15
Autocrine growth stimulation of human renal Wilms' tumour G401 cells by a gastrin-like peptide. 61
8169000 1994
16
Extrarenal Wilms' tumors. A study of their relationship with classical renal Wilms' tumor using expression of WT1 as a molecular marker. 61
8388523 1993
17
Extrarenal Wilms' tumor: staging, treatment, and prognosis. 61
1845874 1991
18
Extrarenal Wilms' tumor: an analysis of four cases. 61
2544508 1989
19
Extra renal Wilms' tumour. 61
201563 1977

Variations for Renal Wilms' Tumor

Expression for Renal Wilms' Tumor

Search GEO for disease gene expression data for Renal Wilms' Tumor.

Pathways for Renal Wilms' Tumor

GO Terms for Renal Wilms' Tumor

Cellular components related to Renal Wilms' Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.43 WT1 TUT7 TUT4 TUT1 SMYD3 PRMT1
2 cytoplasm GO:0005737 9.17 WT1 TUT7 TUT4 TUT1 SMYD3 PRMT1

Biological processes related to Renal Wilms' Tumor according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 mRNA processing GO:0006397 9.69 TUT7 TUT4 TUT1
2 stem cell population maintenance GO:0019827 9.52 TUT4 DIS3L2
3 nuclear-transcribed mRNA poly(A) tail shortening GO:0000289 9.49 TUT7 TUT4
4 oocyte maturation GO:0001556 9.48 TUT7 TUT4
5 miRNA metabolic process GO:0010586 9.46 TUT7 TUT4
6 pre-miRNA processing GO:0031054 9.43 TUT7 TUT4
7 RNA 3'-end processing GO:0031123 9.4 TUT7 TUT4
8 miRNA catabolic process GO:0010587 9.37 TUT4 DIS3L2
9 mRNA polyadenylation GO:0006378 9.33 TUT7 TUT4 TUT1
10 RNA 3' uridylation GO:0071076 9.32 TUT7 TUT4
11 negative regulation of transposition, RNA-mediated GO:0010526 9.26 TUT7 TUT4
12 histone mRNA catabolic process GO:0071044 9.13 TUT7 TUT4 TUT1
13 polyuridylation-dependent mRNA catabolic process GO:1990074 8.8 TUT7 TUT4 DIS3L2

Molecular functions related to Renal Wilms' Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.91 WT1 TUT7 TUT4 TUT1 SMYD3 DIS3L2
2 transferase activity GO:0016740 9.77 TUT7 TUT4 TUT1 SMYD3 PRMT1
3 nucleic acid binding GO:0003676 9.76 WT1 TUT7 TUT4 TUT1
4 RNA binding GO:0003723 9.63 WT1 TUT7 TUT4 TUT1 PRMT1 DIS3L2
5 nucleotidyltransferase activity GO:0016779 9.5 TUT7 TUT4 TUT1
6 miRNA binding GO:0035198 9.4 TUT7 TUT4
7 uridylyltransferase activity GO:0070569 9.26 TUT7 TUT4
8 polynucleotide adenylyltransferase activity GO:0004652 9.13 TUT7 TUT4 TUT1
9 RNA uridylyltransferase activity GO:0050265 8.8 TUT7 TUT4 TUT1

Sources for Renal Wilms' Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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