MCID: RPR001
MIFTS: 20

Reproductive Organ Benign Neoplasm

Categories: Cancer diseases

Aliases & Classifications for Reproductive Organ Benign Neoplasm

MalaCards integrated aliases for Reproductive Organ Benign Neoplasm:

Name: Reproductive Organ Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050622

Summaries for Reproductive Organ Benign Neoplasm

Disease Ontology : 12 An organ system benign neoplasm that is located in reproductive system organs.

MalaCards based summary : Reproductive Organ Benign Neoplasm is related to male reproductive organ benign neoplasm and bizarre leiomyoma. An important gene associated with Reproductive Organ Benign Neoplasm is HPSE2 (Heparanase 2 (Inactive)), and among its related pathways/superpathways is Thyroid hormone signaling pathway. Affiliated tissues include reproductive system organs, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Reproductive Organ Benign Neoplasm

Diseases related to Reproductive Organ Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 84)
# Related Disease Score Top Affiliating Genes
1 male reproductive organ benign neoplasm 12.4
2 bizarre leiomyoma 10.9 MED12 PGR
3 vulvar syringoma 10.9 ESR1 PGR
4 lung leiomyoma 10.9 ESR1 PGR
5 vestibular gland benign neoplasm 10.9 ESR1 PGR
6 bartholin's gland adenoma 10.9 ESR1 PGR
7 glassy cell carcinoma of the cervix 10.9 ESR1 PGR
8 vulvar benign neoplasm 10.9 ESR1 PGR
9 trigonitis 10.9 ESR1 PGR
10 vulvar leiomyoma 10.9 ESR1 PGR
11 breast medullary carcinoma 10.9 ESR1 PGR
12 breast scirrhous carcinoma 10.9 ESR1 PGR
13 progesterone resistance 10.9 ESR1 PGR
14 progesterone-receptor positive breast cancer 10.9 ESR1 PGR
15 cribriform carcinoma 10.9 ESR1 PGR
16 oncocytic breast carcinoma 10.9 ESR1 PGR
17 endometrial squamous cell carcinoma 10.9 ESR1 PGR
18 gastric signet ring cell adenocarcinoma 10.9 ESR1 PGR
19 endometrial mucinous adenocarcinoma 10.9 ESR1 PGR
20 mixed hepatoblastoma 10.9 AFP PGR
21 adenoid basal cell carcinoma 10.9 ESR1 PGR
22 apocrine adenocarcinoma 10.8 ESR1 PGR
23 gender identity disorder 10.8 ESR1 PGR
24 bartholin's gland benign neoplasm 10.8 ESR1 PGR
25 cystic nephroma 10.8 DICER1 PGR
26 deep angioma 10.8 ESR1 PGR
27 synchronous bilateral breast carcinoma 10.8 ESR1 PGR
28 breast adenoid cystic carcinoma 10.8 ESR1 PGR
29 cervical carcinosarcoma 10.8 ESR1 PGR
30 estrogen excess 10.8 ESR1 PGR
31 intramuscular hemangioma 10.8 ESR1 PGR
32 glycogen-rich clear cell breast carcinoma 10.8 ESR1 PGR
33 testicular granulosa cell tumor 10.7 AFP DICER1
34 mammographic density 10.7 ESR1 PGR
35 juvenile type testicular granulosa cell tumor 10.7 AFP DICER1
36 retinitis pigmentosa 47 10.7 ESR1 PGR
37 uterine corpus cancer 10.7 ESR1 PGR
38 adenomyosis 10.7 ESR1 PGR
39 scrotal carcinoma 10.7 AFP HMGA2
40 retinitis pigmentosa 20 10.7 ESR1 PGR
41 breast benign neoplasm 10.7 ESR1 MED12 PGR
42 thoracic benign neoplasm 10.7 ESR1 MED12 PGR
43 luminal breast carcinoma 10.7 ESR1 PGR
44 adenosarcoma 10.6 ESR1 PGR
45 smooth muscle tumor 10.6 ESR1 HMGA2 PGR
46 leiomyosarcoma 10.6 FH MED12 PGR
47 cervical clear cell adenocarcinoma 10.6 ESR1 PGR
48 hepatic angiomyolipoma 10.6 AFP TSC2
49 hereditary renal cell carcinoma 10.5 FH TSC2
50 tubular adenocarcinoma 10.5 AFP ESR1 PGR

Graphical network of the top 20 diseases related to Reproductive Organ Benign Neoplasm:



Diseases related to Reproductive Organ Benign Neoplasm

Symptoms & Phenotypes for Reproductive Organ Benign Neoplasm

GenomeRNAi Phenotypes related to Reproductive Organ Benign Neoplasm according to GeneCards Suite gene sharing:

26 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-108 9.62 MED12 PRDM10 DICER1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.62 MED12
3 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.62 MED12
4 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.62 MED12
5 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.62 PRDM10
6 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.62 PRDM10
7 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.62 MED12 DICER1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.62 MED12
9 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.62 PRDM10
10 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.62 MED12
11 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.62 DICER1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-23 9.62 MED12
13 Increased shRNA abundance (Z-score > 2) GR00366-A-3 9.62 DICER1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.62 DICER1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.62 MED12
16 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.62 DICER1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.62 MED12

MGI Mouse Phenotypes related to Reproductive Organ Benign Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.44 TGFB3 TNRC6B TSC2 AFP DICER1 ESR1

Drugs & Therapeutics for Reproductive Organ Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Reproductive Organ Benign Neoplasm

Genetic Tests for Reproductive Organ Benign Neoplasm

Anatomical Context for Reproductive Organ Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Reproductive Organ Benign Neoplasm:

19
Reproductive System Organs

Publications for Reproductive Organ Benign Neoplasm

Variations for Reproductive Organ Benign Neoplasm

Expression for Reproductive Organ Benign Neoplasm

Search GEO for disease gene expression data for Reproductive Organ Benign Neoplasm.

Pathways for Reproductive Organ Benign Neoplasm

Pathways related to Reproductive Organ Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.86 ESR1 MED12 TSC2

GO Terms for Reproductive Organ Benign Neoplasm

Biological processes related to Reproductive Organ Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular steroid hormone receptor signaling pathway GO:0030518 9.16 ESR1 MED12
2 ovulation from ovarian follicle GO:0001542 8.96 AFP PGR
3 embryonic neurocranium morphogenesis GO:0048702 8.62 MED12 TGFB3

Sources for Reproductive Organ Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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