Respiratory System Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Respiratory System Benign Neoplasm

MalaCards integrated aliases for Respiratory System Benign Neoplasm:

Name: Respiratory System Benign Neoplasm ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0050621

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Summaries for Respiratory System Benign Neoplasm

Disease Ontology : ¹² An organ system benign neoplasm that is located in the respiratory system which extends from the nasal sinuses to the diaphragm.

MalaCards based summary : Respiratory System Benign Neoplasm is related to kyasanur forest disease and st. louis encephalitis. An important gene associated with Respiratory System Benign Neoplasm is KRAS (KRAS Proto-Oncogene, GTPase), and among its related pathways/superpathways are Extracellular vesicle-mediated signaling in recipient cells and G-protein signaling_K-RAS regulation pathway. Affiliated tissues include the respiratory system which extends from the nasal sinuses to the diaphragm.

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Related Diseases for Respiratory System Benign Neoplasm

Diseases in the Respiratory System Cancer family:

Respiratory System Benign Neoplasm

Diseases related to Respiratory System Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 139)

#	Related Disease	Score	Top Affiliating Genes
1	kyasanur forest disease	10.8	KRAS RAF1
2	st. louis encephalitis	10.8	KRAS RAF1
3	murray valley encephalitis	10.8	KRAS RAF1
4	intracranial primitive neuroectodermal tumor	10.8	CHGA ENO2
5	epithelioid malignant peripheral nerve sheath tumor	10.7	CHGA ENO2
6	goblet cell carcinoid	10.7	CHGA ENO2
7	acute thyroiditis	10.7	CHGA ENO2
8	bronchiolo-alveolar adenocarcinoma	10.7	KRAS NKX2-1
9	rete testis adenocarcinoma	10.6	ENO2 NKX2-1
10	adenosquamous cell lung carcinoma	10.6	ENO2 KRAS
11	somatostatinoma	10.6	CHGA ENO2
12	lung adenoid cystic carcinoma	10.6	KRAS NKX2-1
13	epithelioid cell melanoma	10.6	ENO2 MITF
14	duodenal gastrinoma	10.6	CHGA ENO2
15	duodenum cancer	10.6	ENO2 KRAS
16	rete testis neoplasm	10.6	ENO2 NKX2-1
17	liver angiosarcoma	10.6	ENO2 KRAS
18	spinal meningioma	10.6	CHGA ENO2
19	spinal canal and spinal cord meningioma	10.5	CHGA ENO2
20	supraglottis cancer	10.5	ARHGEF6 ENO2
21	diffuse pulmonary fibrosis	10.5	CHGA ENO2
22	malignant sertoli cell tumor	10.5	ENO2 SYP
23	sinonasal undifferentiated carcinoma	10.5	ENO2 SYP
24	sensory organ benign neoplasm	10.5	ENO2 SYP
25	pancreatic somatostatinoma	10.5	ENO2 SYP
26	extrahepatic bile duct adenocarcinoma	10.5	ENO2 SYP
27	papillary tumor of the pineal region	10.5	ENO2 SYP
28	orbital cancer	10.4	ENO2 SYP
29	middle ear adenoma	10.4	ENO2 SYP
30	ovarian carcinosarcoma	10.4	ENO2 SYP
31	central nervous system primitive neuroectodermal neoplasm	10.4	ENO2 SYP
32	cerebellum cancer	10.4	ENO2 SYP
33	subependymal glioma	10.4	ENO2 SYP
34	cerebral neuroblastoma	10.4	ENO2 SYP
35	extraosseous chondrosarcoma	10.4	ENO2 SYP
36	benign ependymoma	10.4	ENO2 SYP
37	astroblastoma	10.4	ENO2 SYP
38	cerebral ventricle cancer	10.4	ENO2 SYP
39	respiratory system cancer	10.4	ENO2 KRAS NKX2-1
40	cerebrum cancer	10.4	ENO2 SYP
41	pineal gland cancer	10.4	ENO2 SYP
42	endometrial small cell carcinoma	10.4	ENO2 SYP
43	melanotic neuroectodermal tumor	10.4	ENO2 SYP
44	supratentorial cancer	10.4	ENO2 SYP
45	ampulla of vater neoplasm	10.4	KRAS SYP
46	mucinous ovarian cystadenoma	10.4	ENO2 SYP
47	angiomyoma	10.4	ENO2 SYP
48	desmoplastic small round cell tumor	10.4	ENO2 SYP
49	bone benign neoplasm	10.4	ENO2 SYP
50	esophageal neuroendocrine tumor	10.4	CHGA SYP

Graphical network of the top 20 diseases related to Respiratory System Benign Neoplasm:

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Symptoms & Phenotypes for Respiratory System Benign Neoplasm

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Drugs & Therapeutics for Respiratory System Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Respiratory System Benign Neoplasm

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Genetic Tests for Respiratory System Benign Neoplasm

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Anatomical Context for Respiratory System Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Respiratory System Benign Neoplasm:

¹⁹

The Respiratory System Which Extends From The Nasal Sinuses To The Diaphragm

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Publications for Respiratory System Benign Neoplasm

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Genes for Respiratory System Benign Neoplasm

Genes related to Respiratory System Benign Neoplasm (0 elite genes):

(show all 12)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	15.93	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	ENO2	Enolase 2	Protein Coding	15.43	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	SLC22A23	Solute Carrier Family 22 Member 23	Protein Coding	15.33	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	15.12	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	PTPN23	Protein Tyrosine Phosphatase, Non-Receptor Type 23	Protein Coding	15.04	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	CHGA	Chromogranin A	Protein Coding	14.66	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	NKX2-1	NK2 Homeobox 1	Protein Coding	14.62	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	MITF	Melanogenesis Associated Transcription Factor	Protein Coding	14.48	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	ARHGEF6	Rac/Cdc42 Guanine Nucleotide Exchange Factor 6	Protein Coding	14.47	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	SYP	Synaptophysin	Protein Coding	14.41	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	CASC1	Cancer Susceptibility 1	Protein Coding	7.25	DISEASES inferred ¹⁵
12	LRMP	Lymphoid Restricted Membrane Protein	Protein Coding	7.02	DISEASES inferred ¹⁵

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Variations for Respiratory System Benign Neoplasm

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Expression for Respiratory System Benign Neoplasm

Search GEO for disease gene expression data for Respiratory System Benign Neoplasm.

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Pathways for Respiratory System Benign Neoplasm

Pathways related to Respiratory System Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Extracellular vesicle-mediated signaling in recipient cells ¹	10.73	KRAS RAF1
2	G-protein signaling_K-RAS regulation pathway ²²	10.59	KRAS RAF1
3	CD209 (DC-SIGN) signaling ⁶⁶	10.3	KRAS RAF1
4	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling ¹	9.92	KRAS RAF1

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GO Terms for Respiratory System Benign Neoplasm

Biological processes related to Respiratory System Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	thyroid gland development	GO:0030878	9.16	NKX2-1 RAF1
2	regulation of long-term neuronal synaptic plasticity	GO:0048169	8.96	KRAS SYP
3	epithelial tube branching involved in lung morphogenesis	GO:0060441	8.62	KRAS NKX2-1

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