Respiratory System Benign Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Respiratory System Benign Neoplasm

MalaCards integrated aliases for Respiratory System Benign Neoplasm:

Name: Respiratory System Benign Neoplasm ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Respiratory diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0050621

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Summaries for Respiratory System Benign Neoplasm

Disease Ontology : ¹² An organ system benign neoplasm that is located in the respiratory system which extends from the nasal sinuses to the diaphragm.

MalaCards based summary : Respiratory System Benign Neoplasm is related to pleural lipoma and trachea leiomyoma. An important gene associated with Respiratory System Benign Neoplasm is NKX2-1 (NK2 Homeobox 1), and among its related pathways/superpathways are Bisphosphonate Pathway, Pharmacodynamics and EGFR Transactivation by Gastrin.

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Related Diseases for Respiratory System Benign Neoplasm

Diseases related to Respiratory System Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)

#	Related Disease	Score	Top Affiliating Genes
1	pleural lipoma	11.2
2	trachea leiomyoma	11.2
3	chromosome 14q11-q22 deletion syndrome	10.4	HRAS NKX2-1
4	sigmoid neoplasm	10.4	HRAS KRAS
5	apocrine adenoma	10.4	HRAS KRAS
6	periampullary adenoma	10.4	HRAS KRAS
7	paronychia	10.4	HRAS KRAS
8	schimmelpenning-feuerstein-mims syndrome	10.4	HRAS KRAS
9	bile duct cysts	10.4	HRAS KRAS
10	ureter small cell carcinoma	10.4	CHGA SYP
11	esophageal neuroendocrine tumor	10.4	CHGA SYP
12	ovarian large-cell neuroendocrine carcinoma	10.4	CHGA SYP
13	aggressive digital papillary adenocarcinoma	10.4	HRAS KRAS
14	acinar cell cystadenocarcinoma	10.4	CHGA SYP
15	peritoneal serous adenocarcinoma	10.4	CHGA SYP
16	cellular ependymoma	10.4	CHGA SYP
17	primary hepatic neuroendocrine carcinoma	10.4	CHGA SYP
18	spinal canal and spinal cord meningioma	10.4	CHGA ENO2
19	carotid body cancer	10.4	ENO2 SYP
20	appendix disease	10.4	HRAS KRAS
21	malignant sertoli cell tumor	10.4	ENO2 SYP
22	malignant struma ovarii	10.4	HRAS NKX2-1
23	gastrointestinal neuroendocrine tumor	10.4	CHGA SYP
24	nasal cavity adenocarcinoma	10.3	HRAS KRAS
25	sinonasal undifferentiated carcinoma	10.3	ENO2 SYP
26	chordoid meningioma	10.3	CHGA SYP
27	pancreatic somatostatinoma	10.3	ENO2 SYP
28	cutaneous ganglioneuroma	10.3	ENO2 SYP
29	extrahepatic bile duct adenocarcinoma	10.3	ENO2 SYP
30	papillary tumor of the pineal region	10.3	ENO2 SYP
31	olfactory groove meningioma	10.3	CHGA SYP
32	sensory organ benign neoplasm	10.3	ENO2 SYP
33	secondary hypertrophic osteoarthropathy	10.3	HRAS KRAS
34	orbital cancer	10.3	ENO2 SYP
35	middle ear adenoma	10.3	ENO2 SYP
36	alveoli adenoma	10.3	KRAS NKX2-1
37	anal canal adenocarcinoma	10.3	HRAS KRAS
38	pancreatic serous cystadenoma	10.3	CHGA SYP
39	conventional angiosarcoma	10.3	CHGA SYP
40	malignant ectomesenchymoma	10.3	ENO2 HRAS
41	ectomesenchymoma	10.3	ENO2 HRAS
42	intracranial primitive neuroectodermal tumor	10.3	CHGA ENO2
43	central nervous system primitive neuroectodermal neoplasm	10.3	ENO2 SYP
44	cerebellum cancer	10.3	ENO2 SYP
45	fetal adenoma	10.3	HRAS NKX2-1
46	clear cell ependymoma	10.3	ENO2 SYP
47	rete testis adenocarcinoma	10.3	ENO2 NKX2-1
48	cerebral neuroblastoma	10.3	ENO2 SYP
49	somatostatinoma	10.3	CHGA ENO2
50	endometrial small cell carcinoma	10.3	ENO2 SYP

Graphical network of the top 20 diseases related to Respiratory System Benign Neoplasm:

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Symptoms & Phenotypes for Respiratory System Benign Neoplasm

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Drugs & Therapeutics for Respiratory System Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Respiratory System Benign Neoplasm

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Genetic Tests for Respiratory System Benign Neoplasm

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Anatomical Context for Respiratory System Benign Neoplasm

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Publications for Respiratory System Benign Neoplasm

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Genes for Respiratory System Benign Neoplasm

Genes related to Respiratory System Benign Neoplasm (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	NKX2-1	NK2 Homeobox 1	Protein Coding	16.52	DISEASES inferred ¹⁵
2	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	15.6	DISEASES inferred ¹⁵
3	MORN1	MORN Repeat Containing 1	Protein Coding	15.48	DISEASES inferred ¹⁵
4	SYP	Synaptophysin	Protein Coding	15.37	DISEASES inferred ¹⁵
5	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	15.37	DISEASES inferred ¹⁵
6	CHGA	Chromogranin A	Protein Coding	15.3	DISEASES inferred ¹⁵
7	ENO2	Enolase 2	Protein Coding	15.26	DISEASES inferred ¹⁵
8	VPS16	VPS16 Core Subunit Of CORVET And HOPS Complexes	Protein Coding	15.22	DISEASES inferred ¹⁵
9	SLC22A23	Solute Carrier Family 22 Member 23	Protein Coding	15.06	DISEASES inferred ¹⁵
10	NAPSA	Napsin A Aspartic Peptidase	Protein Coding	15.01	DISEASES inferred ¹⁵
11	LMNTD1	Lamin Tail Domain Containing 1	Protein Coding	6.97	DISEASES inferred ¹⁵
12	CASC1	Cancer Susceptibility 1	Protein Coding	6.88	DISEASES inferred ¹⁵
13	LRMP	Lymphoid Restricted Membrane Protein	Protein Coding	6.73	DISEASES inferred ¹⁵

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Variations for Respiratory System Benign Neoplasm

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Expression for Respiratory System Benign Neoplasm

Search GEO for disease gene expression data for Respiratory System Benign Neoplasm.

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Pathways for Respiratory System Benign Neoplasm

Pathways related to Respiratory System Benign Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Bisphosphonate Pathway, Pharmacodynamics ⁶² Show member pathways RalA downstream regulated genes ¹	10.83	HRAS KRAS
2	EGFR Transactivation by Gastrin ⁶⁷ Show member pathways EGFR-dependent Endothelin signaling events ¹ SHC-related events triggered by IGF1R ⁶⁷	10.74	HRAS KRAS
3	MNAR-PELP1 and Estrogen Receptor Interaction ⁶⁵	10.62	HRAS KRAS
4	CD209 (DC-SIGN) signaling ⁶⁷	10.5	HRAS KRAS
5	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling ¹	10.26	HRAS KRAS
6	p38MAPK events ⁶⁷	9.74	HRAS KRAS

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GO Terms for Respiratory System Benign Neoplasm

Biological processes related to Respiratory System Benign Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	epithelial tube branching involved in lung morphogenesis	GO:0060441	9.16	KRAS NKX2-1
2	response to isolation stress	GO:0035900	8.96	HRAS KRAS
3	regulation of long-term neuronal synaptic plasticity	GO:0048169	8.8	HRAS KRAS SYP

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Sources for Respiratory System Benign Neoplasm

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