MCID: RSP004
MIFTS: 24

Respiratory System Benign Neoplasm

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Respiratory System Benign Neoplasm

MalaCards integrated aliases for Respiratory System Benign Neoplasm:

Name: Respiratory System Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050621
ICD10 33 D14.4

Summaries for Respiratory System Benign Neoplasm

Disease Ontology : 12 An organ system benign neoplasm that is located in the respiratory system which extends from the nasal sinuses to the diaphragm.

MalaCards based summary : Respiratory System Benign Neoplasm is related to pleural lipoma and trachea leiomyoma. An important gene associated with Respiratory System Benign Neoplasm is NKX2-1 (NK2 Homeobox 1), and among its related pathways/superpathways are ErbB signaling pathway and MicroRNAs in cancer. Related phenotypes are neoplasm and no phenotypic analysis

Related Diseases for Respiratory System Benign Neoplasm

Diseases related to Respiratory System Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)
# Related Disease Score Top Affiliating Genes
1 pleural lipoma 11.3
2 trachea leiomyoma 11.3
3 sigmoid neoplasm 10.8 KRAS HRAS
4 chromosome 14q11-q22 deletion syndrome 10.7 NKX2-1 HRAS
5 apocrine adenoma 10.7 KRAS HRAS
6 rare adenocarcinoma of the breast 10.7 TP53 KRAS
7 paronychia 10.7 KRAS HRAS
8 periampullary adenoma 10.7 KRAS HRAS
9 colloid adenoma 10.7 TP53 NKX2-1
10 hyperplastic polyposis syndrome 10.7 TP53 KRAS
11 schimmelpenning-feuerstein-mims syndrome 10.7 KRAS HRAS
12 spitz nevus 10.6 TP53 HRAS
13 bile duct cysts 10.6 KRAS HRAS
14 lung adenoid cystic carcinoma 10.6 NKX2-1 KRAS HRAS
15 mutyh-associated polyposis 10.6 TP53 KRAS
16 aggressive digital papillary adenocarcinoma 10.6 KRAS HRAS
17 ureter small cell carcinoma 10.6 SYP CHGA
18 esophageal neuroendocrine tumor 10.6 SYP CHGA
19 malignant ectomesenchymoma 10.6 HRAS ENO2
20 ectomesenchymoma 10.6 HRAS ENO2
21 carotid body cancer 10.6 SYP ENO2
22 nasal cavity adenocarcinoma 10.6 TP53 KRAS HRAS
23 appendix disease 10.6 KRAS HRAS
24 ovarian large-cell neuroendocrine carcinoma 10.6 SYP CHGA
25 acinar cell cystadenocarcinoma 10.5 SYP CHGA
26 biliary papillomatosis 10.5 TP53 KRAS HRAS
27 primary hepatic neuroendocrine carcinoma 10.5 SYP CHGA
28 peritoneal serous adenocarcinoma 10.5 SYP CHGA
29 malignant sertoli cell tumor 10.5 SYP ENO2
30 adenosquamous carcinoma 10.5 TP53 NKX2-1 KRAS
31 ampulla of vater cancer 10.5 TP53 KRAS HRAS
32 bile duct adenocarcinoma 10.5 TP53 KRAS HRAS
33 ovary adenocarcinoma 10.5 TP53 KRAS HRAS
34 intestinal benign neoplasm 10.5 TP53 KRAS HRAS
35 sinonasal undifferentiated carcinoma 10.5 SYP ENO2
36 ovary epithelial cancer 10.5 TP53 KRAS HRAS
37 malignant ovarian surface epithelial-stromal neoplasm 10.5 TP53 KRAS HRAS
38 intracranial primitive neuroectodermal tumor 10.5 ENO2 CHGA
39 pancreas disease 10.5 TP53 KRAS HRAS
40 colorectal adenoma 10.5 TP53 KRAS HRAS
41 papillary tumor of the pineal region 10.5 SYP ENO2
42 carcinosarcoma 10.5 TP53 KRAS HRAS
43 fibroepithelial basal cell carcinoma 10.5 TP53 CHGA
44 colonic disease 10.5 TP53 KRAS HRAS
45 leukemia, chronic lymphocytic 2 10.5 TP53 KRAS HRAS
46 colorectal adenocarcinoma 10.5 TP53 KRAS HRAS
47 extrahepatic bile duct adenocarcinoma 10.5 SYP ENO2
48 cutaneous ganglioneuroma 10.5 SYP ENO2
49 pulmonic stenosis 10.5 RAF1 KRAS HRAS
50 gastrointestinal neuroendocrine tumor 10.5 SYP CHGA

Graphical network of the top 20 diseases related to Respiratory System Benign Neoplasm:



Diseases related to Respiratory System Benign Neoplasm

Symptoms & Phenotypes for Respiratory System Benign Neoplasm

MGI Mouse Phenotypes related to Respiratory System Benign Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.5 CASC1 HRAS KRAS NKX2-1 RAF1 TP53
2 no phenotypic analysis MP:0003012 9.17 CHGA HRAS KRAS NKX2-1 RAF1 TP53

Drugs & Therapeutics for Respiratory System Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Respiratory System Benign Neoplasm

Genetic Tests for Respiratory System Benign Neoplasm

Anatomical Context for Respiratory System Benign Neoplasm

Publications for Respiratory System Benign Neoplasm

Variations for Respiratory System Benign Neoplasm

Expression for Respiratory System Benign Neoplasm

Search GEO for disease gene expression data for Respiratory System Benign Neoplasm.

Pathways for Respiratory System Benign Neoplasm

Pathways related to Respiratory System Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 41)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.48 TP53 RAF1 KRAS HRAS
2 12.43 TP53 RAF1 KRAS HRAS
3
Show member pathways
12.4 TP53 RAF1 KRAS HRAS
4 12.18 TP53 RAF1 KRAS HRAS
5
Show member pathways
12.14 TP53 RAF1 KRAS HRAS
6
Show member pathways
12.1 TP53 RAF1 KRAS HRAS
7 12.02 TP53 RAF1 KRAS HRAS
8 12 TP53 RAF1 KRAS HRAS
9
Show member pathways
11.99 RAF1 KRAS HRAS
10 11.99 RAF1 KRAS HRAS
11
Show member pathways
11.98 TP53 RAF1 KRAS HRAS
12 11.94 RAF1 KRAS HRAS
13
Show member pathways
11.94 RAF1 KRAS HRAS
14
Show member pathways
11.94 TP53 RAF1 KRAS HRAS
15 11.9 RAF1 KRAS HRAS
16 11.9 TP53 KRAS HRAS
17 11.89 RAF1 KRAS HRAS
18 11.86 TP53 RAF1 HRAS
19 11.8 RAF1 KRAS HRAS
20 11.78 TP53 RAF1 KRAS HRAS
21 11.74 RAF1 KRAS HRAS
22 11.74 TP53 RAF1 KRAS HRAS
23
Show member pathways
11.71 RAF1 KRAS HRAS
24 11.67 TP53 RAF1 KRAS HRAS
25 11.6 TP53 RAF1 HRAS
26
Show member pathways
11.59 RAF1 KRAS HRAS
27 11.58 TP53 KRAS HRAS
28 11.53 RAF1 KRAS HRAS
29 11.46 TP53 RAF1 KRAS HRAS
30 11.39 RAF1 KRAS HRAS
31 11.34 TP53 RAF1 HRAS
32 11.3 RAF1 KRAS HRAS
33 11.22 TP53 KRAS HRAS
34 11.12 TP53 RAF1 KRAS HRAS
35 11.09 RAF1 KRAS HRAS
36 10.93 RAF1 HRAS
37 10.8 RAF1 HRAS
38 10.78 RAF1 KRAS HRAS
39 10.76 KRAS HRAS
40 10.76 TP53 RAF1 KRAS HRAS
41 10.63 RAF1 KRAS HRAS

GO Terms for Respiratory System Benign Neoplasm

Biological processes related to Respiratory System Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras protein signal transduction GO:0007265 9.43 TP53 KRAS HRAS
2 epithelial tube branching involved in lung morphogenesis GO:0060441 9.32 NKX2-1 KRAS
3 response to isolation stress GO:0035900 9.16 KRAS HRAS
4 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.13 RAF1 KRAS HRAS
5 regulation of long-term neuronal synaptic plasticity GO:0048169 8.8 SYP KRAS HRAS

Sources for Respiratory System Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....