MCID: RSP006
MIFTS: 56

Respiratory System Disease

Categories: Respiratory diseases

Aliases & Classifications for Respiratory System Disease

MalaCards integrated aliases for Respiratory System Disease:

Name: Respiratory System Disease 12 15
Abnormality of the Respiratory System 29 6
Respiratory Tract Diseases 73
Respiration Disorders 73

Classifications:



External Ids:

Disease Ontology 12 DOID:1579
ICD10 33 J96-J99 J98 10
ICD9CM 35 510-519.99 519

Summaries for Respiratory System Disease

Disease Ontology : 12 A disease of anatomical entity that located in the respiratory system which extends from the nasal sinuses to the diaphragm.

MalaCards based summary : Respiratory System Disease, also known as abnormality of the respiratory system, is related to upper respiratory tract disease and peptic ulcer disease, and has symptoms including dyspnea, edema and respiratory distress. An important gene associated with Respiratory System Disease is TLR9 (Toll Like Receptor 9), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Prednisolone and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and kidney, and related phenotypes are homeostasis/metabolism and growth/size/body region

Related Diseases for Respiratory System Disease

Diseases related to Respiratory System Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 394)
# Related Disease Score Top Affiliating Genes
1 upper respiratory tract disease 31.6 CCL11 CXCL8 IL13 IL1B IL4 IL5
2 peptic ulcer disease 30.1 CXCL8 IL1B TNF
3 helicobacter pylori infection 30.0 CXCL8 EGFR IL1B
4 nickel allergic contact dermatitis 10.4 IL13 IL4 IL5
5 tungiasis 10.4 CXCL8 IL4 TNF
6 scleritis 10.4 IL4 IL5 TNF
7 exudative glomerulonephritis 10.4 CXCL8 IL1B TNF
8 filarial elephantiasis 10.4 IL4 IL5 TLR9
9 apple allergy 10.4 IL13 IL4 IL5
10 streptococcal toxic-shock syndrome 10.4 CXCL8 IL6 TNF
11 cardiac sarcoidosis 10.4 CXCL8 IL5 TNF
12 cow milk allergy 10.4 IL5 RNASE3 TNF
13 paragonimiasis 10.4 IL13 IL5 RNASE3
14 paronychia 10.4 EGFR HRAS KRAS
15 milk allergy 10.4 IL4 IL5 RNASE3
16 intestinal schistosomiasis 10.4 IL13 IL4 IL5
17 burning mouth syndrome 10.4 IL6 TNF TRPV1
18 chronic tic disorder 10.4 IL13 IL4 IL5
19 atopic keratoconjunctivitis 10.4 IL4 IL5 RNASE3
20 intrinsic asthma 10.4 IL4 IL5 RNASE3
21 recurrent corneal erosion 10.4 CXCL8 IL1B IL6
22 autoimmune disease of eyes, ear, nose and throat 10.4 IL6 TLR9 TNF
23 lichen disease 10.4 IL4 TLR9 TNF
24 myelitis 10.4 CCL11 IL6 TNF
25 coccidiosis 10.4 IL4 TLR9 TNF
26 angioimmunoblastic lymphadenopathy with dysproteinemia 10.4 IL13 IL5 IL6 TNF
27 cough variant asthma 10.4 IL4 IL5 RNASE3 TRPV1
28 pleomorphic carcinoma 10.4 ALK EGFR TP53
29 actinic prurigo 10.4 IL13 IL1B TNF
30 viral pneumonia 10.4 CRP IL6 TLR9
31 dry eye syndrome 10.4 IL6 TLR9 TNF TRPV1
32 glossitis 10.4 IL1B IL6 TNF
33 strongyloidiasis 10.4 CCL11 IL13 IL5
34 meconium aspiration syndrome 10.4 CXCL8 IL6 TNF
35 laryngitis 10.4 IL1B IL6 TNF
36 spinal disease 10.4 CRP IL6 TUBB3
37 soft tissue sarcoma 10.4 EGFR TNF TP53
38 haemophilus influenzae 10.4 CXCL8 IL1B TNF
39 autoimmune gastritis 10.4 EGFR IL4 IL6 TNF
40 lung adenoid cystic carcinoma 10.4 ALK HRAS KRAS
41 status asthmaticus 10.4 CXCL8 IL5 RNASE3
42 acute vascular insufficiency of intestine 10.4 IL1B IL6 TNF
43 aspergillosis 10.4 IL4 IL5 TLR9 TNF
44 yellow fever 10.4 IL4 IL5 IL6 TLR9
45 filariasis 10.4 IL5 IL6 TLR9 TNF
46 blepharoconjunctivitis 10.4 CCL11 IL4 RNASE3
47 crohn's colitis 10.4 CXCL8 IL1B TNF
48 enterobiasis 10.4 IL13 IL4 IL5
49 osteosclerotic myeloma 10.4 IL1B IL6 TNF
50 parameningeal embryonal rhabdomyosarcoma 10.4 ALK TP53

Comorbidity relations with Respiratory System Disease via Phenotypic Disease Network (PDN):


Acute Cystitis Bronchitis
Heart Disease Hypertension, Essential
Ischemic Heart Disease Respiratory Failure

Graphical network of the top 20 diseases related to Respiratory System Disease:



Diseases related to Respiratory System Disease

Symptoms & Phenotypes for Respiratory System Disease

UMLS symptoms related to Respiratory System Disease:


dyspnea, edema, respiratory distress, apnea, hemoptysis, cyanosis, stridor, rhinorrhea, wheezing, inspiratory stridor, pleuritic pain, coughing, hoarseness, neonatal cyanosis, sore throat, cheyne-stokes respiration, expiratory wheeze, labored breathing, inspiratory wheeze, choking sensation, pathological conditions, signs and symptoms, signs and symptoms of ill-defined conditions, anoxemia, sinus congestion, other symptoms involving respiratory system and chest, bronchorrhea, gasping for breath, symptoms involving respiratory system and other chest symptoms, nasal congestion (finding), nasal irritation, neck tightness, larynx pain

MGI Mouse Phenotypes related to Respiratory System Disease:

46 (show all 19)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.43 ALK AREG CRP EGFR HRAS IL13
2 growth/size/body region MP:0005378 10.39 ALK AREG EGFR HRAS IL13 IL1B
3 immune system MP:0005387 10.36 AREG CCL11 CRP EGFR IL13 IL1B
4 digestive/alimentary MP:0005381 10.35 AREG EGFR HRAS IL13 IL4 IL5
5 cardiovascular system MP:0005385 10.32 AREG CRP EGFR HRAS IL1B IL6
6 hematopoietic system MP:0005397 10.31 AREG CCL11 EGFR IL13 IL1B IL4
7 mortality/aging MP:0010768 10.3 ALK AREG EGFR HRAS IL13 IL1B
8 integument MP:0010771 10.27 ALK AREG EGFR HRAS IL13 IL1B
9 endocrine/exocrine gland MP:0005379 10.26 ALK AREG EGFR HRAS IL13 IL4
10 nervous system MP:0003631 10.22 ALK EGFR HRAS IL13 IL1B IL4
11 craniofacial MP:0005382 10.18 EGFR HRAS IL1B IL4 KRAS SHOX2
12 neoplasm MP:0002006 10.13 ALK EGFR HRAS IL1B IL5 IL6
13 liver/biliary system MP:0005370 10.08 EGFR IL4 IL5 IL6 KRAS TNF
14 no phenotypic analysis MP:0003012 9.97 EGFR HRAS IL13 IL4 KRAS TNF
15 reproductive system MP:0005389 9.96 ALK AREG EGFR IL13 IL4 IL5
16 respiratory system MP:0005388 9.93 ALK CCL11 EGFR HRAS IL13 IL4
17 renal/urinary system MP:0005367 9.92 EGFR HRAS IL4 IL6 KRAS TLR9
18 skeleton MP:0005390 9.7 ALK EGFR HRAS IL13 IL1B IL4
19 vision/eye MP:0005391 9.23 ALK AREG EGFR IL4 IL6 KRAS

Drugs & Therapeutics for Respiratory System Disease

Drugs for Respiratory System Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1229)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 50-24-8 5755
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 83-43-2 6741
3
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 302-25-0
4
Methylprednisolone hemisuccinate Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 2921-57-5
5
Oseltamivir Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 204255-11-8, 196618-13-0 65028
6
Caspofungin Approved Phase 4,Phase 3 179463-17-3, 162808-62-0 468682 2826718
7
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 22916-47-8 4189
8
Ropivacaine Approved Phase 4,Not Applicable 84057-95-4 175805 71273
9 tannic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
10
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 94-09-7, 1994-09-7 2337
11
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-43-4 5816
12
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 329-65-7 838
13
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 85721-33-1 2764
14
Tazobactam Approved Phase 4,Phase 2,Phase 3,Phase 1 89786-04-9 123630
15
Moxifloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 354812-41-2, 151096-09-2 152946
16
Salmon Calcitonin Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 47931-85-1 16129616
17
Penicillin G Approved, Vet_approved Phase 4,Phase 3,Phase 1 61-33-6 5904
18
Piperacillin Approved Phase 4,Phase 2,Phase 3 66258-76-2 43672
19
Clarithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 81103-11-9 84029
20
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 83905-01-5 55185 447043
21
Cefuroxime Approved Phase 4,Phase 3,Phase 2,Not Applicable 55268-75-2 5361202 5479529
22
Budesonide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 51333-22-3 63006 5281004
23
Adenosine Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 58-61-7 60961
24
Terbutaline Approved Phase 4,Phase 3,Phase 1,Not Applicable 23031-25-6 5403
25
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 299-42-3 9294
26
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90-82-4 7028
27
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 93-14-1 3516
28
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 158966-92-8 5281040
29
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 90566-53-3 62924
30
Ipratropium Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 60205-81-4, 22254-24-6 43232
31
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 53-03-2 5865
32
Metoprolol Approved, Investigational Phase 4,Phase 3,Not Applicable 37350-58-6, 51384-51-1 4171
33
Calcium Carbonate Approved, Investigational Phase 4,Phase 3,Not Applicable 471-34-1
34
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 10102-43-9 145068
35
Sulbactam Approved Phase 4,Phase 3,Phase 2,Phase 1 68373-14-8
36
Simvastatin Approved Phase 4,Phase 3,Phase 1,Phase 2 79902-63-9 54454
37
Tobramycin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 32986-56-4 36294 5496
38
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable 564-25-0 54671203
39
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 100986-85-4 149096
40
Ofloxacin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 82419-36-1 4583
41
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 26787-78-0 33613
42
Linezolid Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 165800-03-3 441401
43
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59467-70-8 4192
44
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 57-27-2 5288826
45
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 64-17-5 702
46
Acetylcysteine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 616-91-1 12035
47
Amikacin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 37517-28-5 37768
48
Polyestradiol phosphate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 28014-46-2
49
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 57-63-6 5991
50
Metronidazole Approved Phase 4,Phase 3,Not Applicable 443-48-1 4173

Interventional clinical trials:

(show top 50) (show all 10000)
# Name Status NCT ID Phase Drugs
1 Exacerbation Prevention GOLD IV COPD With Non Invasive Mechanical Ventilation Unknown status NCT01481727 Phase 4
2 Extra-fine Formoterol/Beclomethasone in Asthmatic Crisis Unknown status NCT02345993 Phase 4 Extra fine Formoterol/Beclomethasone
3 Evaluation and Reconditioning of Marginal Lung Donors to Transplantation by ex Vivo Lung Perfusion Unknown status NCT01353105 Phase 4
4 Banlangen Granules Anti-seasonal Influenza Study Unknown status NCT02232945 Phase 4 placebo of oseltamivir phosphate;oseltamivir phosphate;Banlangen (Radix Isatidis) granules;placebo of Banlangen(Radix Isatidis) granules
5 Effect of Vitamin D as Adjunctive Therapy in Patients With Pulmonary Evolution Tuberculosis Unknown status NCT02464683 Phase 4
6 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease Unknown status NCT01595750 Phase 4 Roflumilast 500;Placebo
7 Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease Unknown status NCT01499433 Phase 4 caspofungin
8 Cpap at Delivery Room for Preterm Infants Unknown status NCT01024361 Phase 4
9 Determining the Minimal Effective Volume (MEAV95) for Interscalene Brachial Plexus Block for Surgical Anesthesia Unknown status NCT01703130 Phase 4
10 Normal Oxygenation Versus Hyperoxia in the Intensive Care Unit (ICU) Unknown status NCT01319643 Phase 4 Oxygen
11 Bronchiolitis All-study, SE-Norway Unknown status NCT00817466 Phase 4 Racemic adrenaline;Isotonic saline
12 Procalcitonin as a Marker of Antibiotic Therapy in Patients With Lower Respiratory Tract Infections Unknown status NCT02171338 Phase 4
13 Treatment Efficacy of Budesonide/Formoterol in Cough Variant Asthma and Typical Asthma Patients Unknown status NCT02934945 Phase 4 budesonide 160μg/formoterol 4.5μg
14 Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype Unknown status NCT01431625 Phase 4
15 Assessment of Airway Responsiveness and Treatment Efficacy in Asthmatics Unknown status NCT02574975 Phase 4 methacholine;adenosine monophosphate;leukotriene D4;budesonide /formoterol
16 The Effect of Bronchodilator on Eosinophilic Bronchitis and Cough Variant Asthma Unknown status NCT02002754 Phase 4 Bambuterol Hydrochloride tablets
17 Therapeutic Effect of Different Treatment Course With Inhaled Corticosteroids in Eosinophilic Bronchitis Patients Unknown status NCT02002715 Phase 4 Inhaled budesonide
18 Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD Unknown status NCT02197871 Phase 4
19 Effects of Su-Huang Antitussive Capsule on Cough Variant Asthma Unknown status NCT01584804 Phase 4 Su-Huang antitussive capsule;Sugar pill
20 Effects of Leukotriene Modulator Montelukast on Cough Variant Asthma Unknown status NCT01404013 Phase 4 ICS/LABA;Montelukast;ICS/LABA and Montelukast
21 Efficacy and Safety of add-on Montelukast to Inhaled Budesonide in the Treatment of Nonasthmatic Eosinophilic Bronchitis Unknown status NCT01121016 Phase 4 Montelukast
22 The Efficacy and Safety of Salmeterol/Fluticasone Propionate vs Atropium/Albuterol in Patients COPD Unknown status NCT01243788 Phase 4 Salmeterol/Fluticasone Propionate
23 Description of the Ability to Learn How to Handle Inhaler Devices in COPD Unknown status NCT02813200 Phase 4 Seretide® Diskus® 500/550 μg;Ultibro® Breezhaler® 110/50 μg;Spiriva® Respimat® 2,5 μg
24 Airway Effects of Tiotropium in Patients With COPD Unknown status NCT02683668 Phase 4
25 Seasonal Influenza Vaccine, Quadrivalent Versus Trivalent in Patients With Advanced Chronic Obstructive Pulmonary Disease Unknown status NCT02563184 Phase 4
26 Pulmonary Gas Exchange Response to Indacaterol in COPD Unknown status NCT02547558 Phase 4 Indacaterol
27 A Post-marketing Research on Jinyebaidu Granule in Treating Patients With Acute Upper Respiratory Infection Unknown status NCT02539277 Phase 4 Jinyebaidu granule;Fufangshuanghua granule;Jinyebaidu granule placebo;Fufangshuanghua granule placebo
28 An Efficacy Study of BCS Clearing the Oral Colonized Bacterium in Hospitalized Patients With COPD Unknown status NCT02269800 Phase 4 Benzalkonium chloride solution;Normal saline
29 Strategy to Improve Adherence of Roflumilast Unknown status NCT02018432 Phase 4 Roflumilast escalation dosage;Roflumilast conventional dosage
30 Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT01721291 Phase 4 SALBUTAMOL
31 Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea Symptom of Chronic Obstructive Pulmonary Disease Unknown status NCT01465906 Phase 4 tulobuterol;Tiotropium Bromide;tiotropium bromide
32 Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients Unknown status NCT01131806 Phase 4 fluticasone/ salmeterol 125/25 mcg/puff;fluticasone/ salmeterol 250/25 mcg/puff
33 The Role of Opinion Leaders in Enhancing Evidence-based Care After Chronic Obstructive Pulmonary Disease (COPD) Emergency Department (ED) Visits Unknown status NCT01107613 Phase 4
34 Metoprolol and Formoterol in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00288548 Phase 4 Metoprolol
35 Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial Unknown status NCT00120978 Phase 4 Advair;Flovent
36 Effect of Supplementary Vitamin D in Patients With Diabetes Mellitus and Pulmonary Tuberculosis Unknown status NCT02169570 Phase 4
37 Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure Unknown status NCT01873521 Phase 4
38 Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients Unknown status NCT01382368 Phase 4 Sildenafil
39 Exhaled NO Based Treatment of Chronic Obstructive Pulmonary Disease (COPD), ICS/LABA Versus LAMA Unknown status NCT02546349 Phase 4 fluticasone/salmeterol, tiotropium
40 Comparisons of Inhaled LAMA or ICS+LABA for COPD With Bronchiectasis Unknown status NCT02546297 Phase 4 Symbicort;Tiotropium Bromide
41 Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis Unknown status NCT02507843 Phase 4 Cholecalciferol;Placebo
42 FRC Guided Therapy in Acute Respiratory Failure Unknown status NCT01280019 Phase 4
43 Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
44 EUROPT Clinical Trial to Study the Efficacy of One-Way Valve Implantation (New Treatment Algorithm) in Patients With Heterogeneous Emphysema Unknown status NCT00730301 Phase 4
45 Piperacillin Sodium and Sulbactam Sodium for Injection(2:1) for Treatment of Respiratory and Urinary System Infection Unknown status NCT01760109 Phase 4 Piperacillin Sodium and Sulbactam Sodium
46 Simvastatin in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00680641 Phase 4 Simvastatin;Placebo
47 A Study to Access Safety and Efficacy of Nebulized Tobramycin in Patients With Bronchiectasis Unknown status NCT01677403 Phase 4 Tobramycin;Saline
48 Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS Unknown status NCT01463553 Phase 4
49 Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00857038 Phase 4 Doxycycline;Placebo
50 Clinical Pathway Based on Procalcitonin Levels for the Management of Community-acquired Pneumonia in Outpatients Unknown status NCT02600806 Phase 4 Azithromycin;Levofloxacin

Search NIH Clinical Center for Respiratory System Disease

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for Respiratory System Disease

Genetic tests related to Respiratory System Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Respiratory System 29

Anatomical Context for Respiratory System Disease

MalaCards organs/tissues related to Respiratory System Disease:

41
Lung, Brain, Kidney, Bone, Colon, Pancreas, Thyroid

The Foundational Model of Anatomy Ontology organs/tissues related to Respiratory System Disease:

19
The Respiratory System Which Extends From The Nasal Sinuses To The Diaphragm

Publications for Respiratory System Disease

Articles related to Respiratory System Disease:

# Title Authors Year
1
Respiratory System Disease. ( 27469180 )
2016
2
Helicobacter pylori infection as a possible risk factor for respiratory system disease: a review of the literature. ( 16759841 )
2007
3
Alpha 1-antitrypsin gene polymorphism related to respiratory system disease. ( 2887693 )
1987
4
Death from respiratory system disease among Seventh-Day Adventist men. ( 5953042 )
1966

Variations for Respiratory System Disease

Expression for Respiratory System Disease

Search GEO for disease gene expression data for Respiratory System Disease.

Pathways for Respiratory System Disease

Pathways related to Respiratory System Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.14 CCL11 CRP CXCL8 EGFR HRAS IL13
2
Show member pathways
13.94 ALK AREG CCL11 CXCL8 EGFR HRAS
3
Show member pathways
13.78 ALK CCL11 CXCL8 EGFR HRAS IL13
4
Show member pathways
13.58 ALK AREG CCL11 CXCL8 EGFR HRAS
5
Show member pathways
13.46 CCL11 CXCL8 EGFR HRAS IL13 IL1B
6
Show member pathways
13.41 ALK AREG EGFR HRAS IL6 KRAS
7
Show member pathways
13.37 ALK AREG EGFR HRAS IL6 KRAS
8
Show member pathways
13.35 AREG EGFR HRAS IL1B IL4 KRAS
9
Show member pathways
13.34 AREG CCL11 CXCL8 EGFR HRAS IL13
10
Show member pathways
13.34 ALK AREG CCL11 CXCL8 EGFR HRAS
11
Show member pathways
13.19 CXCL8 EGFR HRAS IL1B IL6 KRAS
12
Show member pathways
13.17 ALK AREG EGFR HRAS IL4 IL6
13
Show member pathways
13.15 AREG EGFR HRAS IL6 KRAS TP53
14
Show member pathways
13.14 AREG EGFR HRAS IL4 IL6 KRAS
15
Show member pathways
13.04 EGFR HRAS IL6 KRAS TNF TP53
16
Show member pathways
13 CCL11 CXCL8 HRAS IL13 IL1B IL4
17
Show member pathways
12.94 CXCL8 IL13 IL1B IL4 IL6 TLR9
18 12.94 ALK CXCL8 EGFR HRAS IL13 IL4
19 12.91 AREG EGFR HRAS IL1B KRAS TNF
20
Show member pathways
12.89 ALK EGFR HRAS IL6 KRAS TP53
21
Show member pathways
12.86 HRAS IL4 IL6 KRAS TNF
22
Show member pathways
12.83 AREG EGFR IL1B IL6 TLR9 TNF
23
Show member pathways
12.81 EGFR HRAS IL1B KRAS TNF TP53
24
Show member pathways
12.77 EGFR HRAS IL1B KRAS TRPV1
25
Show member pathways
12.76 EGFR HRAS IL1B IL6 KRAS TNF
26
Show member pathways
12.74 IL13 IL1B IL4 IL5 IL6 TNF
27
Show member pathways
12.73 HRAS IL13 IL4 IL5 KRAS TNF
28
Show member pathways
12.65 AREG EGFR HRAS KRAS TP53
29
Show member pathways
12.62 EGFR HRAS KRAS TNF TP53
30
Show member pathways
12.61 EGFR HRAS IL13 IL1B IL5 KRAS
31
Show member pathways