MCID: RTT004
MIFTS: 36

Rete Testis Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Rete Testis Adenocarcinoma

MalaCards integrated aliases for Rete Testis Adenocarcinoma:

Name: Rete Testis Adenocarcinoma 12 15 74
Adenocarcinoma of the Rete Testis 12
Adenocarcinoma of Rete Testis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14544
NCIt 51 C8955
UMLS 74 C0863024

Summaries for Rete Testis Adenocarcinoma

Disease Ontology : 12 A rete testis neoplasm that derives from epithelial cells of glandular origin.

MalaCards based summary : Rete Testis Adenocarcinoma, also known as adenocarcinoma of the rete testis, is related to papillary adenocarcinoma and sertoli-leydig cell tumor. An important gene associated with Rete Testis Adenocarcinoma is NKX3-1 (NK3 Homeobox 1), and among its related pathways/superpathways are Pathways in cancer and Cytoskeletal Signaling. Affiliated tissues include testis, prostate and kidney, and related phenotypes are behavior/neurological and cellular

Related Diseases for Rete Testis Adenocarcinoma

Diseases related to Rete Testis Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 261)
# Related Disease Score Top Affiliating Genes
1 papillary adenocarcinoma 30.4 CEACAM5 KRT7 NKX2-1
2 sertoli-leydig cell tumor 29.9 AFP CALB2 KRT7 WT1
3 adenocarcinoma 10.7
4 malignant sertoli cell tumor 10.6 AFP ENO2
5 childhood endodermal sinus tumor 10.5 AFP PAX8
6 basal cell carcinoma, infundibulocystic 10.5 KRT20 PTGER4
7 hepatic angiomyolipoma 10.5 AFP KIT
8 plexiform schwannoma 10.5 ENO2 KIT
9 gastric leiomyosarcoma 10.5 ENO2 KIT
10 goblet cell carcinoid 10.5 ENO2 KRT20
11 mixed germ cell tumor 10.5 AFP KIT
12 mixed type thymoma 10.5 KIT PAX8
13 athyreosis 10.5 NKX2-1 PAX8
14 colloid adenoma 10.5 KRT20 NKX2-1
15 epithelioid trophoblastic tumor 10.5 KRT7 SALL4
16 intrahepatic bile duct adenoma 10.5 AFP KRT7
17 bladder benign neoplasm 10.4 KRT7 PAX8
18 gallbladder small cell carcinoma 10.4 ENO2 KRT7
19 large intestine adenocarcinoma 10.4 KRT20 KRT7
20 anus basaloid carcinoma 10.4 KRT7 PTGER4
21 glandular cystitis 10.4 KRT20 KRT7
22 transverse colon cancer 10.4 KRT20 KRT7
23 testicular granulosa cell tumor 10.4 AFP WT1
24 appendix adenocarcinoma 10.4 KRT20 KRT7
25 linitis plastica 10.4 KRT20 KRT7
26 kidney rhabdoid cancer 10.4 ENO2 WT1
27 nephrogenic adenoma of urinary bladder 10.4 KRT7 PAX8
28 endocervical carcinoma 10.4 KRT7 PAX8
29 cauda equina neoplasm 10.4 ENO2 WT1
30 juvenile type testicular granulosa cell tumor 10.4 AFP WT1
31 jejunal cancer 10.4 KIT KRT7
32 bile duct adenoma 10.4 KRT20 KRT7
33 adenoid squamous cell carcinoma 10.4 KRT20 KRT7
34 eyelid carcinoma 10.4 KRT20 KRT7
35 peritoneal serous adenocarcinoma 10.4 PTGER4 WT1
36 krukenberg carcinoma 10.4 KRT20 KRT7
37 solid adenocarcinoma with mucin production 10.4 KRT7 NKX2-1
38 prostate sarcoma 10.4 KLK3 NKX3-1
39 cribriform carcinoma 10.4 KIT KRT7
40 papillary adenoma 10.4 KRT7 NKX2-1
41 peritoneal serous papillary adenocarcinoma 10.4 PTGER4 WT1
42 tuberculous epididymitis 10.4 AFP KLK3
43 benign breast adenomyoepithelioma 10.4 KRT5 KRT7
44 ovarian germ cell teratoma 10.4 KRT7 NKX2-1
45 testicular gonadoblastoma 10.4 KIT WT1
46 inverted transitional papilloma 10.4 KRT5 KRT7
47 apocrine sweat gland neoplasm 10.4 KRT5 KRT7
48 prostate embryonal rhabdomyosarcoma 10.4 KIT KLK3
49 prostate rhabdomyosarcoma 10.4 KIT KLK3
50 hematocele of tunica vaginalis testis 10.4 AFP CEACAM5

Graphical network of the top 20 diseases related to Rete Testis Adenocarcinoma:



Diseases related to Rete Testis Adenocarcinoma

Symptoms & Phenotypes for Rete Testis Adenocarcinoma

MGI Mouse Phenotypes related to Rete Testis Adenocarcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.11 AFP CALB2 ENO2 EPCAM KIT KRT5
2 cellular MP:0005384 10.06 ENO2 EPCAM KIT KRT7 NKX2-1 NKX3-1
3 homeostasis/metabolism MP:0005376 9.93 AFP EPCAM KIT KRT7 MME NKX2-1
4 digestive/alimentary MP:0005381 9.8 EPCAM KIT KRT5 NKX2-1 NKX3-1 SALL4
5 neoplasm MP:0002006 9.43 AFP KIT NKX2-1 NKX3-1 PTGER4 WT1
6 no phenotypic analysis MP:0003012 9.17 EPCAM KIT KRT5 NKX2-1 NKX3-1 PAX8

Drugs & Therapeutics for Rete Testis Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Rete Testis Adenocarcinoma

Genetic Tests for Rete Testis Adenocarcinoma

Anatomical Context for Rete Testis Adenocarcinoma

MalaCards organs/tissues related to Rete Testis Adenocarcinoma:

42
Testis, Prostate, Kidney, Thymus, Ovary, Lymph Node, Colon

Publications for Rete Testis Adenocarcinoma

Articles related to Rete Testis Adenocarcinoma:

(show all 42)
# Title Authors Year
1
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature. ( 30676333 )
2019
2
Aggressive surgical management of adenocarcinoma of the rete testis. ( 29226092 )
2018
3
Adenocarcinoma of the rete testis with prominent papillary structure and clear neoplastic cells: morphologic and immunohistochemical findings and differential diagnosis. ( 25885143 )
2015
4
Primary adenocarcinoma of the rete testis: A case report and review of the literature. ( 24396468 )
2014
5
Adenocarcinoma of the rete testis - a rare case of testicular malignancy. ( 24739050 )
2014
6
A case of adenocarcinoma of the rete testis accompanied by focal adenomatous hyperplasia. ( 23800084 )
2013
7
Primary adenocarcinoma of the rete testis with preceding detection of unilateral hydronephrosis. ( 23789053 )
2013
8
Primary adenocarcinoma of the rete testis: improved staging accuracy with CT-PET. ( 20451971 )
2011
9
Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. ( 17853037 )
2008
10
Adenocarcinoma of the rete testis with uncommon presentation as haematocele. ( 18043825 )
2007
11
Serous papillary adenocarcinoma of the rete testis: unusual ultrasonography and pathological findings. ( 17998718 )
2007
12
Primary adenocarcinoma of the rete testis with preceding diagnosis of pulmonary metastases. ( 17118031 )
2006
13
Cutaneous metastases from adenocarcinoma of the rete testis. ( 16420316 )
2006
14
Primary adenocarcinoma of the rete testis. ( 15160542 )
2003
15
Adenocarcinoma of the rete testis presenting in an undescended testicle. ( 14501749 )
2003
16
Adenocarcinoma of the rete testis. Report of two cases. ( 11436150 )
2000
17
Adenocarcinoma of the rete testis. ( 10992394 )
2000
18
Adenocarcinoma of the rete testis. ( 9890544 )
1998
19
Rete testis adenocarcinoma recurring in the inguinal lymph nodes. A case report. ( 9413766 )
1997
20
Adenocarcinoma of the rete testis: report of a case with surgical history of adenomatous hyperplasia of the rete testis. ( 9302160 )
1997
21
Primary adenocarcinoma of the rete testis. ( 9052496 )
1997
22
Adenocarcinoma of the rete testis. ( 8986044 )
1996
23
Adenocarcinoma of the rete testis. ( 7571213 )
1995
24
Papillary adenocarcinoma of the rete testis: a case report and review of the literature. ( 7941203 )
1994
25
Spontaneous rete testis adenocarcinoma in a Fischer 344 rat: a cytomorphological and ultrastructural study. ( 1874987 )
1991
26
Ultrastructure of metastatic rete testis adenocarcinoma. ( 2294871 )
1990
27
Adenocarcinoma of the rete testis with sertoliform differentiation. ( 2802947 )
1989
28
Adenocarcinoma of the rete testis with a spindle cell component. A possible metaplastic carcinoma. ( 2663132 )
1989
29
Mixed Sertoli-Leydig cell tumor and rete testis adenocarcinoma in rats treated with CdCl2. ( 2834860 )
1988
30
Rete testis adenocarcinoma. ( 3202251 )
1988
31
Papillary adenocarcinoma of the rete testis: sonographic findings. ( 3554934 )
1987
32
Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. ( 3799821 )
1986
33
Adenocarcinoma of the rete testis. ( 4079428 )
1985
34
Adenocarcinoma of the rete testis. Case report, ultrastructural observations, and clinicopathologic correlates. ( 6465420 )
1984
35
Papillary adenocarcinoma of the rete testis: a case report. ( 7083116 )
1982
36
Adenocarcinoma of the rete testis 21 years after orchiopexy: case report and review of the literature. ( 6110786 )
1981
37
Adenocarcinoma of the rete testis: a review of the literature and presentation of a case with associated asbestosis. ( 856716 )
1977
38
Adenocarcinoma of the rete testis: report of a case. ( 4699684 )
1973
39
Adenocarcinoma of the rete testis. ( 5033987 )
1972
40
ADENOCARCINOMA OF THE RETE TESTIS. ( 14104423 )
1964
41
Adenocarcinoma of the rete testis. ( 14443337 )
1959
42
A case of adenocarcinoma of the rete testis. ( 14879015 )
1951

Variations for Rete Testis Adenocarcinoma

Expression for Rete Testis Adenocarcinoma

Search GEO for disease gene expression data for Rete Testis Adenocarcinoma.

Pathways for Rete Testis Adenocarcinoma

Pathways related to Rete Testis Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.28 KIT KLK3 NKX3-1 PAX8 PTGER4
2 12.05 EPCAM KRT20 KRT5 KRT7
3 10.86 KIT MME TNFRSF8
4 10.79 EPCAM KIT MME THBD

GO Terms for Rete Testis Adenocarcinoma

Cellular components related to Rete Testis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.23 CEACAM5 ENO2 EPCAM KLK3 KRT5 KRT7

Biological processes related to Rete Testis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.54 KRT20 KRT5 KRT7
2 male gonad development GO:0008584 9.43 KIT NKX3-1 WT1
3 urogenital system development GO:0001655 9.32 NKX3-1 PAX8
4 cellular response to gonadotropin stimulus GO:0071371 9.16 PAX8 WT1
5 metanephric epithelium development GO:0072207 8.96 PAX8 WT1
6 metanephric S-shaped body morphogenesis GO:0072284 8.62 PAX8 WT1

Molecular functions related to Rete Testis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.86 AFP ENO2 EPCAM KIT KLK3 KRT20
2 transcription regulatory region DNA binding GO:0044212 8.92 NKX2-1 NKX3-1 PAX8 WT1

Sources for Rete Testis Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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