MCID: RTT004
MIFTS: 32

Rete Testis Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Rete Testis Adenocarcinoma

MalaCards integrated aliases for Rete Testis Adenocarcinoma:

Name: Rete Testis Adenocarcinoma 12 15 72
Adenocarcinoma of the Rete Testis 12
Adenocarcinoma of Rete Testis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14544
NCIt 50 C8955
UMLS 72 C0863024

Summaries for Rete Testis Adenocarcinoma

Disease Ontology : 12 A rete testis neoplasm that derives from epithelial cells of glandular origin.

MalaCards based summary : Rete Testis Adenocarcinoma, also known as adenocarcinoma of the rete testis, is related to benign mesothelioma and papillary adenocarcinoma. An important gene associated with Rete Testis Adenocarcinoma is NKX3-1 (NK3 Homeobox 1), and among its related pathways/superpathways are Pathways in cancer and Cytoskeletal Signaling. Affiliated tissues include testis and lymph node, and related phenotypes are behavior/neurological and cellular

Related Diseases for Rete Testis Adenocarcinoma

Diseases related to Rete Testis Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 268)
# Related Disease Score Top Affiliating Genes
1 benign mesothelioma 30.4 WT1 PTGER4 KRT7 KRT5
2 papillary adenocarcinoma 30.2 NKX2-1 KRT7 CEACAM5
3 sertoli-leydig cell tumor 29.8 WT1 KRT7 CALB2 AFP
4 wilms tumor 1 29.6 WT1 PAX8 KRT7 ENO2 CALB2
5 renal cell carcinoma, nonpapillary 28.2 WT1 PAX8 NKX2-1 MME KRT7 KRT20
6 mesothelioma, malignant 27.7 WT1 THBD NKX2-1 KRT7 KRT20 CEACAM5
7 malignant sertoli cell tumor 10.8 ENO2 AFP
8 childhood endodermal sinus tumor 10.8 PAX8 AFP
9 adenocarcinoma 10.8
10 mixed germ cell tumor 10.7 KIT AFP
11 hepatic angiomyolipoma 10.7 KIT AFP
12 malignant teratoma 10.7 SALL4 ENO2 AFP
13 basal cell carcinoma, infundibulocystic 10.7 PTGER4 KRT20
14 goblet cell carcinoid 10.6 KRT20 ENO2
15 peritoneal serous papillary adenocarcinoma 10.6 WT1 PTGER4
16 colloid adenoma 10.6 NKX2-1 KRT20
17 athyreosis 10.6 PAX8 NKX2-1
18 testicular gonadoblastoma 10.6 WT1 KIT
19 gastric leiomyosarcoma 10.6 KIT ENO2
20 endometrial small cell carcinoma 10.6 KIT ENO2 AFP
21 prostate sarcoma 10.6 NKX3-1 KLK3
22 juvenile type testicular granulosa cell tumor 10.6 WT1 AFP
23 testicular granulosa cell tumor 10.6 WT1 AFP
24 intrahepatic bile duct adenoma 10.6 KRT7 AFP
25 peritoneal serous adenocarcinoma 10.6 WT1 PTGER4
26 prostate embryonal rhabdomyosarcoma 10.6 KLK3 KIT
27 cutaneous ganglioneuroma 10.6 KRT20 KIT ENO2
28 combined thymoma 10.6 SALL4 PAX8 KRT5
29 nephrogenic adenoma of urinary bladder 10.6 PAX8 KRT7
30 tuberculous epididymitis 10.6 KLK3 AFP
31 anus basaloid carcinoma 10.6 PTGER4 KRT7
32 mixed type thymoma 10.5 PAX8 KIT
33 bile duct adenoma 10.5 KRT7 KRT20
34 ovarian solid teratoma 10.5 TNFRSF8 AFP
35 bladder benign neoplasm 10.5 PAX8 KRT7
36 appendix adenocarcinoma 10.5 KRT7 KRT20
37 transverse colon cancer 10.5 KRT7 KRT20
38 krukenberg carcinoma 10.5 KRT7 KRT20
39 eyelid carcinoma 10.5 KRT7 KRT20
40 sternum cancer 10.5 TNFRSF8 AFP
41 skin benign neoplasm 10.5 KRT5 KRT20 ENO2
42 jejunal cancer 10.5 KRT7 KIT
43 endodermal sinus tumor 10.5 SALL4 KLK3 AFP
44 glandular cystitis 10.5 KRT7 KRT20
45 inverted transitional papilloma 10.5 KRT7 KRT5
46 linitis plastica 10.5 KRT7 KRT20
47 benign breast adenomyoepithelioma 10.5 KRT7 KRT5
48 ovarian germ cell teratoma 10.5 NKX2-1 KRT7
49 large intestine adenocarcinoma 10.4 KRT7 KRT20
50 solid adenocarcinoma with mucin production 10.4 NKX2-1 KRT7

Graphical network of the top 20 diseases related to Rete Testis Adenocarcinoma:



Diseases related to Rete Testis Adenocarcinoma

Symptoms & Phenotypes for Rete Testis Adenocarcinoma

MGI Mouse Phenotypes related to Rete Testis Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.11 AFP CALB2 ENO2 EPCAM KIT KRT5
2 cellular MP:0005384 10.06 ENO2 EPCAM KIT KRT7 NKX2-1 NKX3-1
3 homeostasis/metabolism MP:0005376 9.93 AFP EPCAM KIT KRT7 MME NKX2-1
4 digestive/alimentary MP:0005381 9.8 EPCAM KIT KRT5 NKX2-1 NKX3-1 SALL4
5 neoplasm MP:0002006 9.43 AFP KIT NKX2-1 NKX3-1 PTGER4 WT1
6 no phenotypic analysis MP:0003012 9.17 EPCAM KIT KRT5 NKX2-1 NKX3-1 PAX8

Drugs & Therapeutics for Rete Testis Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Rete Testis Adenocarcinoma

Genetic Tests for Rete Testis Adenocarcinoma

Anatomical Context for Rete Testis Adenocarcinoma

MalaCards organs/tissues related to Rete Testis Adenocarcinoma:

41
Testis, Lymph Node

Publications for Rete Testis Adenocarcinoma

Articles related to Rete Testis Adenocarcinoma:

(show top 50) (show all 65)
# Title Authors PMID Year
1
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature. 38
30676333 2019
2
[Secondary pseudopriapism after lymphatic invasion in a patient with adenocarcinoma of the rete testis]. 38
30691590 2019
3
Aggressive surgical management of adenocarcinoma of the rete testis. 38
29226092 2018
4
Primary adenocarcinoma of the rete testis with elevation of serum carcinoembryonic antigen: a case report. 38
31149477 2017
5
Adenocarcinoma of the rete testis with prominent papillary structure and clear neoplastic cells: morphologic and immunohistochemical findings and differential diagnosis. 38
25885143 2015
6
Primary adenocarcinoma of rete testis with distinct biphasic pattern: An extremely rare entity and diagnostic challenge. 38
25810664 2015
7
Primary adenocarcinoma of the rete testis: A case report and review of the literature. 38
24396468 2014
8
Adenocarcinoma of the rete testis - a rare case of testicular malignancy. 38
24739050 2014
9
A case of adenocarcinoma of the rete testis accompanied by focal adenomatous hyperplasia. 38
23800084 2013
10
Primary adenocarcinoma of the rete testis with preceding detection of unilateral hydronephrosis. 38
23789053 2013
11
Primary adenocarcinoma of the rete testis: improved staging accuracy with CT-PET. 38
20451971 2011
12
[Adenocarcinoma of the rete testis. A case report]. 38
21174741 2010
13
Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. 38
17853037 2008
14
Adenocarcinoma of the rete testis with uncommon presentation as haematocele. 38
18043825 2007
15
Serous papillary adenocarcinoma of the rete testis: unusual ultrasonography and pathological findings. 38
17998718 2007
16
Primary adenocarcinoma of the rete testis with preceding diagnosis of pulmonary metastases. 38
17118031 2006
17
Cutaneous metastases from adenocarcinoma of the rete testis. 38
16420316 2006
18
First cases of animal diseases published since 2000. 6. First update of dog diseases. 38
15072137 2004
19
Rete testis mucinous adenocarcinoma in a dog. 38
14715972 2004
20
Adenocarcinoma of the rete testis presenting in an undescended testicle. 38
14501749 2003
21
Adenomatous hyperplasia of the rete testis. A review and report of new cases. 38
12792886 2003
22
Primary adenocarcinoma of the rete testis. 38
15160542 2003
23
Adenocarcinoma of the rete testis. 38
10992394 2000
24
Adenocarcinoma of the rete testis. Report of two cases. 38
11436150 2000
25
Vasitis nodosa: immunohistochemical findings--case report. 38
10843416 2000
26
[A case of papillary cystadenoma of the epididymis]. 38
9866383 1998
27
Adenocarcinoma of the rete testis. 38
9890544 1998
28
Adenocarcinoma of the rete testis: report of a case with surgical history of adenomatous hyperplasia of the rete testis. 38
9302160 1997
29
Primary adenocarcinoma of the rete testis. 38
9052496 1997
30
Rete testis adenocarcinoma recurring in the inguinal lymph nodes. A case report. 38
9413766 1997
31
Adenocarcinoma of the rete testis. 38
8986044 1996
32
Adenocarcinoma of the rete testis. 38
7571213 1995
33
[Papillary adenocarcinoma of the rete testis. Report of a case]. 38
7661648 1995
34
[Adenocarcinoma of the rete testis. Apropos of a case]. 38
7545497 1995
35
Papillary adenocarcinoma of the rete testis: a case report and review of the literature. 38
7941203 1994
36
Adenocarcinoma of rete testis. Role of inguinal orchiectomy plus retroperitoneal lymph node dissection. 38
2038794 1991
37
Spontaneous rete testis adenocarcinoma in a Fischer 344 rat: a cytomorphological and ultrastructural study. 38
1874987 1991
38
[Adenocarcinoma of the rete testis. Review of the literature apropos of a new case]. 38
2021274 1991
39
Ultrastructure of metastatic rete testis adenocarcinoma. 38
2294871 1990
40
Adenocarcinoma of the rete testis with sertoliform differentiation. 38
2802947 1989
41
[Adenocarcinoma of rete testis]. 38
2692445 1989
42
Adenocarcinoma of the rete testis with a spindle cell component. A possible metaplastic carcinoma. 38
2663132 1989
43
Rete testis adenocarcinoma. 38
3202251 1988
44
Papillary adenocarcinoma of rete testis. Autopsy findings, histochemistry, immunohistochemistry, ultrastructure, and clinical correlations. 38
3287961 1988
45
Mixed Sertoli-Leydig cell tumor and rete testis adenocarcinoma in rats treated with CdCl2. 38
2834860 1988
46
Testicular tumors in mice exposed in utero to diethylstilbestrol. 38
3682076 1987
47
Papillary adenocarcinoma of the rete testis: sonographic findings. 38
3554934 1987
48
Cystadenocarcinoma of the rete testis. 38
3586165 1987
49
Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. 38
3799821 1986
50
Lesions of the rete testis in mice exposed prenatally to diethylstilbestrol. 38
4027990 1985

Variations for Rete Testis Adenocarcinoma

Expression for Rete Testis Adenocarcinoma

Search GEO for disease gene expression data for Rete Testis Adenocarcinoma.

Pathways for Rete Testis Adenocarcinoma

Pathways related to Rete Testis Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.28 PTGER4 PAX8 NKX3-1 KLK3 KIT
2 12.05 KRT7 KRT5 KRT20 EPCAM
3 10.86 TNFRSF8 MME KIT
4 10.79 THBD MME KIT EPCAM

GO Terms for Rete Testis Adenocarcinoma

Cellular components related to Rete Testis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.23 TNFRSF8 MME KRT7 KRT5 KLK3 EPCAM

Biological processes related to Rete Testis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.54 KRT7 KRT5 KRT20
2 male gonad development GO:0008584 9.43 WT1 NKX3-1 KIT
3 urogenital system development GO:0001655 9.32 PAX8 NKX3-1
4 cellular response to gonadotropin stimulus GO:0071371 9.16 WT1 PAX8
5 metanephric S-shaped body morphogenesis GO:0072284 8.96 WT1 PAX8
6 metanephric epithelium development GO:0072207 8.62 WT1 PAX8

Molecular functions related to Rete Testis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.86 WT1 THBD SALL4 PTGER4 PAX8 NKX3-1
2 transcription regulatory region DNA binding GO:0044212 8.92 WT1 PAX8 NKX3-1 NKX2-1

Sources for Rete Testis Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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