MCID: RTT003
MIFTS: 23

Rete Testis Adenoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Rete Testis Adenoma

MalaCards integrated aliases for Rete Testis Adenoma:

Name: Rete Testis Adenoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:6483
NCIt 50 C39956
UMLS 70 C1514910

Summaries for Rete Testis Adenoma

Disease Ontology : 12 A male reproductive organ benign neoplasm that derives from epithelial tissue in which tumor cells form glands or glandlike structures and that is located in the rete testis.

MalaCards based summary : Rete Testis Adenoma is related to adenoma and cryptorchidism, unilateral or bilateral. An important gene associated with Rete Testis Adenoma is PAX2 (Paired Box 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include rete testis, testis and thymus.

Related Diseases for Rete Testis Adenoma

Diseases related to Rete Testis Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 adenoma 10.2
2 cryptorchidism, unilateral or bilateral 10.1
3 gonadoblastoma 10.1
4 inguinal hernia 10.1
5 nephrogenic adenoma 10.0 PAX8 PAX2
6 clear cell adenocarcinoma 10.0 PAX8 PAX2
7 bladder benign neoplasm 10.0 PAX8 PAX2
8 nephrogenic adenoma of urinary bladder 10.0 PAX8 PAX2
9 wolffian duct adenoma 10.0 PAX8 PAX2
10 ovarian large-cell neuroendocrine carcinoma 10.0 PAX8 NCAM1
11 ureterocele 10.0 PAX8 PAX2
12 renal adenoma 10.0 PAX8 PAX2
13 bladder clear cell adenocarcinoma 9.9 PAX8 PAX2
14 kidney benign neoplasm 9.9 PAX8 PAX2
15 papillorenal syndrome 9.9 PAX8 PAX2
16 adenocarcinoma in situ 9.9 PAX8 PAX2
17 endocervical adenocarcinoma 9.9 PAX8 PAX2
18 fallopian tube carcinosarcoma 9.9 NCAM1 CALB2
19 adult type testicular granulosa cell tumor 9.9 NCAM1 CALB2
20 papillary thymic adenocarcinoma 9.9 NCAM1 CALB2
21 epididymal neoplasm 9.9 PAX2 CALB2
22 infected hydrocele 9.9 NCAM1 CALB2
23 hemangioblastoma 9.9 PAX8 PAX2
24 ovarian serous adenofibroma 9.8 NCAM1 CALB2
25 ovarian serous cystadenofibroma 9.8 NCAM1 CALB2
26 rete testis neoplasm 9.8 PAX8 CALB2
27 carcinosarcoma 9.8 PAX8 CALB2
28 rete testis adenocarcinoma 9.8 PAX8 CALB2
29 cakut 9.8 PAX8 PAX2
30 wolffian duct adenocarcinoma 9.8 PAX8 CALB2
31 uterus perivascular epithelioid cell tumor 9.8 PAX8 CALB2
32 cystadenofibroma 9.8 PAX8 CALB2
33 adenofibroma 9.8 PAX8 CALB2
34 thymus clear cell carcinoma 9.8 PAX8 CALB2
35 thyroid gland follicular carcinoma 9.8 PAX8 NCAM1
36 peritoneal serous adenocarcinoma 9.8 PAX8 CALB2
37 epithelioid cell synovial sarcoma 9.8 PAX8 CALB2
38 ovarian benign neoplasm 9.8 PAX8 CALB2
39 seminal vesicle adenocarcinoma 9.8 PAX8 CALB2
40 peritoneum cancer 9.8 PAX8 CALB2
41 papillary serous adenocarcinoma 9.7 PAX8 CALB2
42 renal hypodysplasia/aplasia 1 9.7 PAX8 PAX2
43 mixed cell type cancer 9.7 PAX8 CALB2
44 ovarian cystadenocarcinoma 9.7 PAX8 CALB2
45 nasal cavity olfactory neuroblastoma 9.7 PAX8 PAX2 NCAM1
46 ovarian serous carcinoma 9.7 PAX8 CALB2
47 thymic carcinoma 9.7 PAX8 CALB2
48 renal cell carcinoma, papillary, 1 9.7 PAX8 PAX2
49 papillary carcinoma 9.7 PAX8 CALB2
50 nephrogenic adenoma of the urethra 9.5 PAX8 PAX2 CALB2

Graphical network of the top 20 diseases related to Rete Testis Adenoma:



Diseases related to Rete Testis Adenoma

Symptoms & Phenotypes for Rete Testis Adenoma

Drugs & Therapeutics for Rete Testis Adenoma

Search Clinical Trials , NIH Clinical Center for Rete Testis Adenoma

Genetic Tests for Rete Testis Adenoma

Anatomical Context for Rete Testis Adenoma

The Foundational Model of Anatomy Ontology organs/tissues related to Rete Testis Adenoma:

19
Rete Testis

MalaCards organs/tissues related to Rete Testis Adenoma:

40
Testis, Thymus, Kidney, Thyroid, Uterus

Publications for Rete Testis Adenoma

Articles related to Rete Testis Adenoma:

# Title Authors PMID Year
1
Appendageal tumors and tumor-like lesions of the testis and paratestis: a 32-year experience at a single institution. 61
32619438 2020
2
Comparative immunomorphology of testicular Sertoli and sertoliform tumors. 61
27939779 2017
3
Polyorchidism and rete testis adenoma: ultrasound and MR findings. 61
8832875 1996
4
Coexisting rete testis adenoma and gonadoblastoma. 61
7062394 1982

Variations for Rete Testis Adenoma

Expression for Rete Testis Adenoma

Search GEO for disease gene expression data for Rete Testis Adenoma.

Pathways for Rete Testis Adenoma

Pathways related to Rete Testis Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.28 PAX2 NCAM1
2 10.85 PAX2 NCAM1
3 9.83 PAX8 PAX2

GO Terms for Rete Testis Adenoma

Biological processes related to Rete Testis Adenoma according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 anatomical structure development GO:0048856 9.58 PAX8 PAX2
2 inner ear morphogenesis GO:0042472 9.58 PAX8 PAX2
3 branching involved in ureteric bud morphogenesis GO:0001658 9.57 PAX8 PAX2
4 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.56 PAX8 PAX2
5 urogenital system development GO:0001655 9.55 PAX8 PAX2
6 mesonephros development GO:0001823 9.54 PAX8 PAX2
7 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.52 PAX8 PAX2
8 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.51 PAX8 PAX2
9 pronephros development GO:0048793 9.49 PAX8 PAX2
10 metanephric epithelium development GO:0072207 9.48 PAX8 PAX2
11 metanephric nephron tubule formation GO:0072289 9.46 PAX8 PAX2
12 metanephric distal convoluted tubule development GO:0072221 9.43 PAX8 PAX2
13 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.4 PAX8 PAX2
14 positive regulation of metanephric DCT cell differentiation GO:2000594 9.37 PAX8 PAX2
15 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.32 PAX8 PAX2
16 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.26 PAX8 PAX2
17 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.16 PAX8 PAX2
18 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 8.96 PAX8 PAX2
19 pronephric field specification GO:0039003 8.62 PAX8 PAX2

Sources for Rete Testis Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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