MCID: RTT005
MIFTS: 24

Rete Testis Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Rete Testis Neoplasm

MalaCards integrated aliases for Rete Testis Neoplasm:

Name: Rete Testis Neoplasm 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5639
NCIt 50 C39955
UMLS 73 C1514912

Summaries for Rete Testis Neoplasm

MalaCards based summary : Rete Testis Neoplasm is related to rete testis adenocarcinoma and nephrogenic adenoma of urinary bladder. An important gene associated with Rete Testis Neoplasm is PAX2 (Paired Box 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Adhesion. Affiliated tissues include testis.

Related Diseases for Rete Testis Neoplasm

Diseases related to Rete Testis Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 195)
# Related Disease Score Top Affiliating Genes
1 rete testis adenocarcinoma 25.9 AFP CALB2 CEACAM5 ENO2 KIT KLK3
2 nephrogenic adenoma of urinary bladder 11.0 PAX2 PAX8
3 bladder benign neoplasm 11.0 PAX2 PAX8
4 endosalpingiosis 10.9 PAX8 PTGER4
5 mature teratoma of the ovary 10.9 ENO2 KRT20
6 cystic basal cell carcinoma 10.9 KRT20 PTGER4
7 malignant sertoli cell tumor 10.9 AFP ENO2
8 goblet cell carcinoid 10.9 ENO2 KRT20
9 malignant syringoma 10.8 KRT20 PTGER4
10 basal cell carcinoma, infundibulocystic 10.8 KRT20 PTGER4
11 athyreosis 10.8 NKX2-1 PAX8
12 renal pelvis adenocarcinoma 10.8 AFP PAX8
13 lung acinar adenocarcinoma 10.8 KRT20 NKX2-1
14 malignant epithelial mesothelioma 10.8 PTGER4 THBD
15 peritoneum cancer 10.8 PAX8 PTGER4
16 prostate small cell carcinoma 10.8 ENO2 KLK3
17 ovarian germ cell cancer 10.7 AFP NKX2-1
18 head injury 10.7 ENO2 THBD
19 hypothyroidism, congenital, nongoitrous, 2 10.7 NKX2-1 PAX8
20 respiratory system benign neoplasm 10.7 ENO2 NKX2-1
21 seminal vesicle adenocarcinoma 10.7 KLK3 KRT20
22 nodular prostate 10.7 ENO2 KLK3
23 retinal hemangioblastoma 10.7 ENO2 PAX2 PAX8
24 renal pelvis carcinoma 10.7 KRT20 PAX8
25 clear cell hidradenoma 10.7 MME PAX8
26 malignant struma ovarii 10.7 AFP NKX2-1
27 multiple mucosal neuroma 10.7 ENO2 NCAM1
28 tuberculous epididymitis 10.6 AFP KLK3
29 carcinoid tumors, intestinal 10.6 ENO2 NKX2-1
30 endocervical adenocarcinoma 10.6 KRT20 PAX2 PAX8
31 adenocarcinoma in situ 10.6 KRT20 PAX2 PAX8
32 lung meningioma 10.6 ENO2 NCAM1
33 epididymis cancer 10.6 CEACAM5 PTGER4
34 epididymis adenocarcinoma 10.6 CEACAM5 PTGER4
35 sensory organ benign neoplasm 10.6 ENO2 NCAM1
36 renal adenoma 10.6 NCAM1 PAX2
37 gallbladder small cell carcinoma 10.6 ENO2 NCAM1
38 urethra adenocarcinoma 10.6 KLK3 PAX8
39 sarcomatoid mesothelioma 10.6 NKX2-1 THBD
40 choriocarcinoma of ovary 10.6 ENO2 NCAM1
41 urethra clear cell adenocarcinoma 10.6 KLK3 PAX8
42 orbital cancer 10.6 ENO2 NCAM1
43 childhood endodermal sinus tumor 10.6 AFP PAX2 PAX8
44 atypical follicular adenoma 10.6 CEACAM5 ENO2
45 ovarian large-cell neuroendocrine carcinoma 10.6 KRT20 NCAM1
46 bladder lymphoma 10.6 KRT20 MME
47 small cell carcinoma of the bladder 10.6 ENO2 KRT20 NKX2-1
48 cystic teratoma 10.6 ENO2 KRT20 NKX2-1
49 mucinous cystadenofibroma 10.6 AFP CEACAM5
50 urachal adenocarcinoma 10.6 AFP CEACAM5

Graphical network of the top 20 diseases related to Rete Testis Neoplasm:



Diseases related to Rete Testis Neoplasm

Symptoms & Phenotypes for Rete Testis Neoplasm

Drugs & Therapeutics for Rete Testis Neoplasm

Search Clinical Trials , NIH Clinical Center for Rete Testis Neoplasm

Genetic Tests for Rete Testis Neoplasm

Anatomical Context for Rete Testis Neoplasm

MalaCards organs/tissues related to Rete Testis Neoplasm:

41
Testis

Publications for Rete Testis Neoplasm

Variations for Rete Testis Neoplasm

Expression for Rete Testis Neoplasm

Search GEO for disease gene expression data for Rete Testis Neoplasm.

Pathways for Rete Testis Neoplasm

GO Terms for Rete Testis Neoplasm

Biological processes related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 thyroid gland development GO:0030878 9.58 NKX2-1 PAX8
2 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.57 PAX2 PAX8
3 negative regulation of programmed cell death GO:0043069 9.56 KIT PAX2
4 urogenital system development GO:0001655 9.55 PAX2 PAX8
5 mesonephros development GO:0001823 9.54 PAX2 PAX8
6 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.52 PAX2 PAX8
7 pronephros development GO:0048793 9.51 PAX2 PAX8
8 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.49 PAX2 PAX8
9 metanephric epithelium development GO:0072207 9.48 PAX2 PAX8
10 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.46 PAX2 PAX8
11 metanephric nephron tubule formation GO:0072289 9.43 PAX2 PAX8
12 metanephric distal convoluted tubule development GO:0072221 9.4 PAX2 PAX8
13 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.37 PAX2 PAX8
14 pronephric field specification GO:0039003 9.32 PAX2 PAX8
15 positive regulation of metanephric DCT cell differentiation GO:2000594 9.26 PAX2 PAX8
16 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.16 PAX2 PAX8
17 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 8.96 PAX2 PAX8
18 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 8.62 PAX2 PAX8

Sources for Rete Testis Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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