MCID: RTT005
MIFTS: 16

Rete Testis Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Rete Testis Neoplasm

MalaCards integrated aliases for Rete Testis Neoplasm:

Name: Rete Testis Neoplasm 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5639
NCIt 50 C39955
UMLS 70 C1514912

Summaries for Rete Testis Neoplasm

MalaCards based summary : Rete Testis Neoplasm is related to rete testis adenocarcinoma and leydig cell tumor. An important gene associated with Rete Testis Neoplasm is NKX3-1 (NK3 Homeobox 1), and among its related pathways/superpathways is Pathways in cancer. Affiliated tissues include testis, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Rete Testis Neoplasm

Diseases related to Rete Testis Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 147)
# Related Disease Score Top Affiliating Genes
1 rete testis adenocarcinoma 30.2 PTGER4 PAX8 NKX3-1 KRT7 CALB2 AFP
2 leydig cell tumor 10.1 CALB2 AFP
3 malignant epithelial mesothelioma 10.1 PTGER4 CALB2
4 adult type testicular granulosa cell tumor 10.1 CALB2 AFP
5 testicular granulosa cell tumor 10.1 CALB2 AFP
6 dermoid cyst of ovary 10.1 CALB2 AFP
7 papillary thymic adenocarcinoma 10.1 PTGER4 CALB2
8 spermatocele 10.1 CALB2 AFP
9 infected hydrocele 10.1 CALB2 AFP
10 testicular fibroma 10.1 CALB2 AFP
11 lymphohistiocytoid mesothelioma 10.1 PTGER4 CALB2
12 juvenile type testicular granulosa cell tumor 10.1 CALB2 AFP
13 ovarian gonadoblastoma 10.1 CALB2 AFP
14 prostatic acinar adenocarcinoma 10.1 PAX8 NKX3-1
15 cystic lymphangioma 10.1 CALB2 AFP
16 rete testis adenoma 10.1 PAX8 CALB2
17 cervical clear cell adenocarcinoma 10.0 PAX8 AFP
18 fallopian tube endometrioid adenocarcinoma 10.0 PAX8 CALB2
19 ovarian mixed germ cell neoplasm 10.0 PAX8 AFP
20 ovarian cystadenocarcinoma 10.0 PAX8 CALB2
21 bartholin's gland disease 10.0 KRT7 CALB2
22 omphalocele 9.9 CALB2 AFP
23 pancreatic mucinous cystadenoma 9.9 KRT7 CALB2
24 mucinous stomach adenocarcinoma 9.9 KRT7 CALB2
25 ovarian serous carcinoma 9.9 PAX8 CALB2
26 ovarian serous adenofibroma 9.9 KRT7 CALB2
27 ovarian serous cystadenofibroma 9.9 KRT7 CALB2
28 lung leiomyosarcoma 9.9 KRT7 CALB2
29 anus basaloid carcinoma 9.9 PTGER4 KRT7
30 bladder leiomyoma 9.9 KRT7 CALB2
31 ovarian sex-cord stromal tumor 9.9 KRT7 CALB2
32 rectum neuroendocrine neoplasm 9.9 KRT7 AFP
33 bile duct cystadenocarcinoma 9.9 KRT7 AFP
34 ovarian primitive germ cell tumor 9.9 KRT7 AFP
35 ovarian endodermal sinus tumor 9.9 KRT7 AFP
36 endodermal sinus tumor 9.9 KRT7 AFP
37 colonic lymphangioma 9.9 KRT7 AFP
38 mesenchymal chondrosarcoma 9.9 NKX3-1 KRT7
39 intratubular embryonal carcinoma 9.9 KRT7 AFP
40 malignant syringoma 9.9 PTGER4 KRT7
41 monophasic synovial sarcoma 9.9 KRT7 CALB2
42 middle ear adenocarcinoma 9.9 KRT7 AFP
43 large cell acanthoma 9.9 PTGER4 KRT7
44 pulmonary sclerosing hemangioma 9.9 KRT7 CALB2
45 liver sarcoma 9.9 KRT7 AFP
46 eccrine sweat gland cancer 9.9 PTGER4 KRT7
47 horseshoe kidney 9.9 KRT7 CALB2
48 medulloepithelioma 9.9 KRT7 CALB2
49 biliary tract benign neoplasm 9.9 KRT7 AFP
50 sarcomatous intrahepatic cholangiocarcinoma 9.9 KRT7 AFP

Graphical network of the top 20 diseases related to Rete Testis Neoplasm:



Diseases related to Rete Testis Neoplasm

Symptoms & Phenotypes for Rete Testis Neoplasm

GenomeRNAi Phenotypes related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-114 9.17 AFP
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-120 9.17 AFP
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-29 9.17 AFP
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-63 9.17 AFP
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.17 AFP
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.17 KRT7
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-75 9.17 AFP

Drugs & Therapeutics for Rete Testis Neoplasm

Search Clinical Trials , NIH Clinical Center for Rete Testis Neoplasm

Genetic Tests for Rete Testis Neoplasm

Anatomical Context for Rete Testis Neoplasm

MalaCards organs/tissues related to Rete Testis Neoplasm:

40
Testis

Publications for Rete Testis Neoplasm

Variations for Rete Testis Neoplasm

Expression for Rete Testis Neoplasm

Search GEO for disease gene expression data for Rete Testis Neoplasm.

Pathways for Rete Testis Neoplasm

Pathways related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.52 PTGER4 PAX8 NKX3-1

GO Terms for Rete Testis Neoplasm

Biological processes related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 urogenital system development GO:0001655 8.62 PAX8 NKX3-1

Sources for Rete Testis Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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