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MCID: RTT005
MIFTS: 26

Rete Testis Neoplasm

Categories: Cancer diseases, Reproductive diseases
Genes Tissues Related diseases Pathways
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Aliases & Classifications for Rete Testis Neoplasm

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MalaCards integrated aliases for Rete Testis Neoplasm:

Name: Rete Testis Neoplasm 12 15 73

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:5639
NCIt 50 C39955
UMLS 73 C1514912
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Summaries for Rete Testis Neoplasm

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MalaCards based summary : Rete Testis Neoplasm is related to rete testis adenocarcinoma and peritoneum cancer. An important gene associated with Rete Testis Neoplasm is PAX2 (Paired Box 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Adhesion. Affiliated tissues include testis, lung and kidney.

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Related Diseases for Rete Testis Neoplasm

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Diseases related to Rete Testis Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 206)
# Related Disease Score Top Affiliating Genes
1 rete testis adenocarcinoma 30.2 AFP CALB2 CEACAM5 ENO2 KIT KLK3
2 peritoneum cancer 10.3 PAX8 PTGER4
3 lymphoepithelioma-like carcinoma 10.3 ENO2 KRT20
4 carcinoid tumors, intestinal 10.3 ENO2 NKX2-1
5 respiratory system benign neoplasm 10.3 ENO2 NKX2-1
6 extraskeletal ewing sarcoma 10.3 ENO2 NKX2-1
7 renal pelvis carcinoma 10.3 KRT20 PAX8
8 hypothyroidism, congenital, nongoitrous, 2 10.3 NKX2-1 PAX8
9 nephrogenic adenoma of urinary bladder 10.3 PAX2 PAX8
10 bladder benign neoplasm 10.3 PAX2 PAX8
11 cystic basal cell carcinoma 10.3 KRT20 PTGER4
12 sarcomatoid mesothelioma 10.3 NKX2-1 THBD
13 malignant syringoma 10.3 KRT20 PTGER4
14 papillary transitional carcinoma 10.3 ENO2 KRT20
15 endosalpingiosis 10.2 PAX8 PTGER4
16 malignant struma ovarii 10.2 AFP NKX2-1
17 villous adenoma 10.2 KLK3 KRT20
18 sensory organ benign neoplasm 10.2 ENO2 PAX8
19 urethral diverticulum 10.2 KLK3 PAX8
20 basal cell carcinoma, infundibulocystic 10.2 KRT20 PTGER4
21 malignant sertoli cell tumor 10.2 AFP ENO2
22 malignant epithelial mesothelioma 10.2 PTGER4 THBD
23 lung acinar adenocarcinoma 10.2 KRT20 NKX2-1
24 goblet cell carcinoid 10.2 ENO2 KRT20
25 male reproductive organ benign neoplasm 10.2 AFP KLK3
26 bladder neck obstruction 10.2 AFP KLK3
27 athyreosis 10.2 NKX2-1 PAX8
28 chondroid chordoma 10.2 CEACAM5 ENO2
29 colloid adenoma 10.2 KRT20 NKX2-1
30 cervical clear cell adenocarcinoma 10.2 ENO2 NCAM1
31 gastric squamous cell carcinoma 10.2 ENO2 NCAM1
32 seminal vesicle tumor 10.2 AFP KLK3
33 subependymoma 10.2 ENO2 NCAM1
34 pericardial tuberculosis 10.2 CEACAM5 PTGER4
35 renal pelvis adenocarcinoma 10.2 AFP PAX8
36 endodermal sinus tumor 10.2 AFP KLK3
37 seminal vesicle adenocarcinoma 10.2 KLK3 KRT20
38 rectum adenocarcinoma 10.2 CEACAM5 KRT20
39 vulva adenocarcinoma 10.2 CEACAM5 KRT20
40 biliary papillomatosis 10.2 CEACAM5 KRT20
41 ovarian mucinous neoplasm 10.2 CEACAM5 KRT20
42 retinal hemangioblastoma 10.2 ENO2 PAX2 PAX8
43 intestinal perforation 10.2 NCAM1 NKX2-1
44 multiple mucosal neuroma 10.2 ENO2 NCAM1
45 fetal adenoma 10.2 CEACAM5 NKX2-1
46 epididymis cancer 10.2 CEACAM5 PTGER4
47 ovarian germ cell cancer 10.2 AFP NKX2-1
48 epididymis adenocarcinoma 10.2 CEACAM5 PTGER4
49 lung meningioma 10.2 ENO2 NCAM1
50 endocervical adenocarcinoma 10.2 KRT20 PAX2 PAX8

Graphical network of the top 20 diseases related to Rete Testis Neoplasm:



Diseases related to Rete Testis Neoplasm
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Symptoms & Phenotypes for Rete Testis Neoplasm

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Drugs & Therapeutics for Rete Testis Neoplasm

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Search Clinical Trials , NIH Clinical Center for Rete Testis Neoplasm

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Genetic Tests for Rete Testis Neoplasm

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Anatomical Context for Rete Testis Neoplasm

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MalaCards organs/tissues related to Rete Testis Neoplasm:

41
Testis, Lung, Kidney, Liver, Colon, Prostate, Thyroid
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Publications for Rete Testis Neoplasm

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Variations for Rete Testis Neoplasm

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Expression for Rete Testis Neoplasm

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Search GEO for disease gene expression data for Rete Testis Neoplasm.
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Pathways for Rete Testis Neoplasm

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Pathways related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers 65
11.62 AFP NCAM1 PAX2
2
Adhesion 4
11.52 CEACAM5 KLK3 NCAM1
3
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 65
11.32 CEACAM5 KIT MME NCAM1
4
Dendritic Cells Developmental Lineage Pathway 65
10.79 KIT MME NCAM1 THBD
5
ID signaling pathway 1
10.36 PAX2 PAX8
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GO Terms for Rete Testis Neoplasm

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Biological processes related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 thyroid gland development GO:0030878 9.58 NKX2-1 PAX8
2 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.57 PAX2 PAX8
3 urogenital system development GO:0001655 9.56 PAX2 PAX8
4 negative regulation of programmed cell death GO:0043069 9.55 KIT PAX2
5 mesonephros development GO:0001823 9.54 PAX2 PAX8
6 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.52 PAX2 PAX8
7 pronephros development GO:0048793 9.51 PAX2 PAX8
8 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.49 PAX2 PAX8
9 metanephric epithelium development GO:0072207 9.48 PAX2 PAX8
10 metanephric distal convoluted tubule development GO:0072221 9.46 PAX2 PAX8
11 metanephric nephron tubule formation GO:0072289 9.43 PAX2 PAX8
12 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.4 PAX2 PAX8
13 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.37 PAX2 PAX8
14 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.32 PAX2 PAX8
15 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.26 PAX2 PAX8
16 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.16 PAX2 PAX8
17 positive regulation of metanephric DCT cell differentiation GO:2000594 8.96 PAX2 PAX8
18 pronephric field specification GO:0039003 8.62 PAX2 PAX8
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Sources for Rete Testis Neoplasm

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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