Rete Testis Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Rete Testis Neoplasm

MalaCards integrated aliases for Rete Testis Neoplasm:

Name: Rete Testis Neoplasm ¹² ¹⁵ ⁷⁰

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:5639

NCIt ⁵⁰ C39955

UMLS ⁷⁰ C1514912

Sources

Summaries for Rete Testis Neoplasm

MalaCards based summary : Rete Testis Neoplasm is related to rete testis adenocarcinoma and leydig cell tumor. An important gene associated with Rete Testis Neoplasm is NKX3-1 (NK3 Homeobox 1), and among its related pathways/superpathways is Pathways in cancer. Affiliated tissues include testis, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Sources

Related Diseases for Rete Testis Neoplasm

Diseases related to Rete Testis Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 147)

#	Related Disease	Score	Top Affiliating Genes
1	rete testis adenocarcinoma	30.2	PTGER4 PAX8 NKX3-1 KRT7 CALB2 AFP
2	leydig cell tumor	10.1	CALB2 AFP
3	malignant epithelial mesothelioma	10.1	PTGER4 CALB2
4	adult type testicular granulosa cell tumor	10.1	CALB2 AFP
5	testicular granulosa cell tumor	10.1	CALB2 AFP
6	dermoid cyst of ovary	10.1	CALB2 AFP
7	papillary thymic adenocarcinoma	10.1	PTGER4 CALB2
8	spermatocele	10.1	CALB2 AFP
9	infected hydrocele	10.1	CALB2 AFP
10	testicular fibroma	10.1	CALB2 AFP
11	lymphohistiocytoid mesothelioma	10.1	PTGER4 CALB2
12	juvenile type testicular granulosa cell tumor	10.1	CALB2 AFP
13	ovarian gonadoblastoma	10.1	CALB2 AFP
14	prostatic acinar adenocarcinoma	10.1	PAX8 NKX3-1
15	cystic lymphangioma	10.1	CALB2 AFP
16	rete testis adenoma	10.1	PAX8 CALB2
17	cervical clear cell adenocarcinoma	10.0	PAX8 AFP
18	fallopian tube endometrioid adenocarcinoma	10.0	PAX8 CALB2
19	ovarian mixed germ cell neoplasm	10.0	PAX8 AFP
20	ovarian cystadenocarcinoma	10.0	PAX8 CALB2
21	bartholin's gland disease	10.0	KRT7 CALB2
22	omphalocele	9.9	CALB2 AFP
23	pancreatic mucinous cystadenoma	9.9	KRT7 CALB2
24	mucinous stomach adenocarcinoma	9.9	KRT7 CALB2
25	ovarian serous carcinoma	9.9	PAX8 CALB2
26	ovarian serous adenofibroma	9.9	KRT7 CALB2
27	ovarian serous cystadenofibroma	9.9	KRT7 CALB2
28	lung leiomyosarcoma	9.9	KRT7 CALB2
29	anus basaloid carcinoma	9.9	PTGER4 KRT7
30	bladder leiomyoma	9.9	KRT7 CALB2
31	ovarian sex-cord stromal tumor	9.9	KRT7 CALB2
32	rectum neuroendocrine neoplasm	9.9	KRT7 AFP
33	bile duct cystadenocarcinoma	9.9	KRT7 AFP
34	ovarian primitive germ cell tumor	9.9	KRT7 AFP
35	ovarian endodermal sinus tumor	9.9	KRT7 AFP
36	endodermal sinus tumor	9.9	KRT7 AFP
37	colonic lymphangioma	9.9	KRT7 AFP
38	mesenchymal chondrosarcoma	9.9	NKX3-1 KRT7
39	intratubular embryonal carcinoma	9.9	KRT7 AFP
40	malignant syringoma	9.9	PTGER4 KRT7
41	monophasic synovial sarcoma	9.9	KRT7 CALB2
42	middle ear adenocarcinoma	9.9	KRT7 AFP
43	large cell acanthoma	9.9	PTGER4 KRT7
44	pulmonary sclerosing hemangioma	9.9	KRT7 CALB2
45	liver sarcoma	9.9	KRT7 AFP
46	eccrine sweat gland cancer	9.9	PTGER4 KRT7
47	horseshoe kidney	9.9	KRT7 CALB2
48	medulloepithelioma	9.9	KRT7 CALB2
49	biliary tract benign neoplasm	9.9	KRT7 AFP
50	sarcomatous intrahepatic cholangiocarcinoma	9.9	KRT7 AFP

Graphical network of the top 20 diseases related to Rete Testis Neoplasm:

Sources

Symptoms & Phenotypes for Rete Testis Neoplasm

GenomeRNAi Phenotypes related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased shRNA abundance (Z-score < -2)	GR00366-A-114	9.17	AFP
2	Decreased shRNA abundance (Z-score < -2)	GR00366-A-120	9.17	AFP
3	Decreased shRNA abundance (Z-score < -2)	GR00366-A-29	9.17	AFP
4	Decreased shRNA abundance (Z-score < -2)	GR00366-A-63	9.17	AFP
5	Decreased shRNA abundance (Z-score < -2)	GR00366-A-65	9.17	AFP
6	Decreased shRNA abundance (Z-score < -2)	GR00366-A-71	9.17	KRT7
7	Decreased shRNA abundance (Z-score < -2)	GR00366-A-75	9.17	AFP

Sources

Drugs & Therapeutics for Rete Testis Neoplasm

Search Clinical Trials , NIH Clinical Center for Rete Testis Neoplasm

Sources

Genetic Tests for Rete Testis Neoplasm

Sources

Anatomical Context for Rete Testis Neoplasm

MalaCards organs/tissues related to Rete Testis Neoplasm:

⁴⁰

Testis

Sources

Publications for Rete Testis Neoplasm

Sources

Genes for Rete Testis Neoplasm

Genes related to Rete Testis Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	NKX3-1	NK3 Homeobox 1	Protein Coding	6.05	DISEASES inferred ¹⁵
2	CALB2	Calbindin 2	Protein Coding	5.98	DISEASES inferred ¹⁵
3	AFP	Alpha Fetoprotein	Protein Coding	5.72	DISEASES inferred ¹⁵
4	PAX8	Paired Box 8	Protein Coding	5.68	DISEASES inferred ¹⁵
5	KRT7	Keratin 7	Protein Coding	5.46	DISEASES inferred ¹⁵
6	PTGER4	Prostaglandin E Receptor 4	Protein Coding	5.42	DISEASES inferred ¹⁵

Sources

Variations for Rete Testis Neoplasm

Sources

Expression for Rete Testis Neoplasm

Search GEO for disease gene expression data for Rete Testis Neoplasm.

Sources

Pathways for Rete Testis Neoplasm

Pathways related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Pathways in cancer ³⁶	11.52	PTGER4 PAX8 NKX3-1

Sources

GO Terms for Rete Testis Neoplasm

Biological processes related to Rete Testis Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	urogenital system development	GO:0001655	8.62	PAX8 NKX3-1

Sources

Sources for Rete Testis Neoplasm

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Apr-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia