MCID: RTN011
MIFTS: 25

Retina Lymphoma

Categories: Blood diseases, Cancer diseases, Eye diseases, Immune diseases, Neuronal diseases

Aliases & Classifications for Retina Lymphoma

MalaCards integrated aliases for Retina Lymphoma:

Name: Retina Lymphoma 12 15
Lymphoma of Retina 12 70
Retinal Lymphoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:774
NCIt 50 C4365
SNOMED-CT 67 232075002
UMLS 70 C0339556

Summaries for Retina Lymphoma

MalaCards based summary : Retina Lymphoma, also known as lymphoma of retina, is related to intraocular lymphoma and uveitis. An important gene associated with Retina Lymphoma is IGHV4-38-2 (Immunoglobulin Heavy Variable 4-38-2), and among its related pathways/superpathways are Allograft rejection and NF-kappaB Signaling. Affiliated tissues include retina and eye.

Related Diseases for Retina Lymphoma

Diseases related to Retina Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 intraocular lymphoma 30.0 IL10 IGHV4-38-2 CXCR5
2 uveitis 29.3 IL10 CXCR5
3 b-cell lymphoma 29.3 CXCR5 CXCL13 BCL10
4 schuurs-hoeijmakers syndrome 10.1 IGLL5 IGHV4-38-2
5 hyperpigmentation with or without hypopigmentation, familial progressive 10.1 IGLL5 IGHV4-38-2
6 retinitis pigmentosa 24 10.1 IGLL5 IGHV4-38-2
7 splenic disease 10.1 IL10 IGHV4-38-2
8 amebiasis 10.1 IL10 IGLL5
9 b cell deficiency 10.1 IL10 IGHV4-38-2
10 mikulicz disease 10.0 IL10 CXCR5
11 diffuse large b-cell lymphoma 10.0
12 mature b-cell neoplasm 10.0 IGLL5 IGHV4-38-2
13 tracheal lymphoma 10.0 IGHV4-38-2 CXCL13
14 tertiary syphilis 10.0 IL10 CXCL13
15 lymphoma 10.0
16 leukocyte disease 10.0 IL10 IGHV4-38-2
17 multicentric castleman disease 10.0 IL10 CXCL13
18 castleman disease 10.0 IL10 CXCL13
19 primary central nervous system lymphoma 9.9 CXCR5 CXCL13
20 aseptic meningitis 9.9 IL10 CXCL13
21 tick-borne encephalitis 9.9 IL10 CXCL13
22 orofaciodigital syndrome viii 9.9 IGHV4-38-2 BCL10
23 sleeping sickness 9.9 IL10 CXCL13
24 reticulum cell sarcoma 9.9
25 sjogren syndrome 9.9 IL10 CXCL13
26 marginal zone b-cell lymphoma 9.9 IGHV4-38-2 BCL10
27 central nervous system hematologic cancer 9.8 IL10 IGHV4-38-2 CXCL13
28 omenn syndrome 9.7 IL10 IGHV4-38-2
29 b-lymphoblastic leukemia/lymphoma 9.7 CXCR5 CXCL13
30 pars planitis 9.7
31 peripheral t-cell lymphoma 9.7
32 cytomegalovirus retinitis 9.7
33 neuroretinitis 9.7
34 panuveitis 9.7
35 papilledema 9.7
36 retinitis 9.7
37 macular retinal edema 9.7
38 toxoplasmosis 9.7
39 ocular toxoplasmosis 9.7
40 neurosyphilis 9.7 IL10 CXCR5 CXCL13
41 autoimmune disease of exocrine system 9.7 IL10 CXCR5 CXCL13
42 central nervous system lymphoma 9.7 IL10 CXCR5 CXCL13
43 potocki-shaffer syndrome 9.7 IL10 CXCR5 CXCL13
44 sezary's disease 9.7 IL10 BCL10
45 burkitt lymphoma 9.7 IL10 CXCR5 CXCL13
46 lymphoma, non-hodgkin, familial 9.5 IGHV4-38-2 CXCR5 BCL10
47 eye lymphoma 9.5 IL10 IGHV4-38-2 CXCR5 CXCL13
48 leukemia, chronic lymphocytic 9.4 IL10 IGHV4-38-2 CXCR5 BCL10
49 gastric lymphoma 9.3 IGHV4-38-2 CXCR5 CXCL13 BCL10
50 lymphoma, mucosa-associated lymphoid type 9.3 IGHV4-38-2 CXCR5 CXCL13 BCL10

Graphical network of the top 20 diseases related to Retina Lymphoma:



Diseases related to Retina Lymphoma

Symptoms & Phenotypes for Retina Lymphoma

Drugs & Therapeutics for Retina Lymphoma

Search Clinical Trials , NIH Clinical Center for Retina Lymphoma

Genetic Tests for Retina Lymphoma

Anatomical Context for Retina Lymphoma

MalaCards organs/tissues related to Retina Lymphoma:

40
Retina, Eye

Publications for Retina Lymphoma

Articles related to Retina Lymphoma:

(show all 23)
# Title Authors PMID Year
1
Lymphoma masquerading as occlusive retinal vasculitis: A case study. 61
32613135 2020
2
Optic Nerve Infiltration in Systemic Metastatic Retinal Lymphoma (SMRL): Multimodal Imaging and Challenges in Diagnosis. 61
32967510 2020
3
Choroidal neovascularization as a complication of primary vitreous retinal lymphoma. 61
32551977 2020
4
Use of FDG-PET/CT for systemic assessment of suspected primary central nervous system lymphoma: a LOC study. 61
32405997 2020
5
An audit of retinal lymphoma treatment at the University of California San Francisco. 61
31358925 2020
6
Clinical Features of Primary and Systemic Metastatic Intraocular Lymphomas in Spanish Patients. 61
31737358 2019
7
A Case of Primary Vitreous Retinal Lymphoma. 61
29271394 2018
8
Clinical Features of Systemic Metastatic Retinal Lymphoma in Japanese Patients. 61
27070953 2017
9
Canine and feline retinal lymphoma: a retrospective review of 12 cases. 61
26868476 2017
10
Distinct Profiles of Soluble Cytokine Receptors Between B-Cell Vitreoretinal Lymphoma and Uveitis. 61
26595610 2015
11
Improving the cytological diagnosis of intraocular lymphoma from vitreous fluid. 61
25413989 2015
12
Toxicity of a biodegradable microneedle implant loaded with methotrexate as a sustained release device in normal rabbit eye: a pilot study. 61
21323470 2011
13
Diagnosis of systemic metastatic retinal lymphoma. 61
19958292 2011
14
Primary intraocular (retinal) lymphoma after ocular toxoplasmosis. 61
20454548 2010
15
The future of primary intraocular lymphoma (retinal lymphoma). 61
20001255 2009
16
Primary intraocular lymphoma. 61
19653715 2009
17
Pathophysiology of retinal lymphoma. 61
19657975 2009
18
Ocular imaging in primary retinal lymphoma. 61
19376328 2009
19
The pathologist's perspective on vitreous opacities. 61
18344965 2008
20
Acquired immunodeficiency syndrome-related intraocular B-cell lymphoma. 61
10326958 1999
21
Human T-cell lymphotropic virus type I-associated retinal lymphoma. A clinicopathologic report. 61
8031276 1994
22
[Retinal lymphoma--simulating uveitis]. 61
1405400 1992
23
[Retinal lymphoma, retinal necrosis: identification of retinal viral particles and anti-herpetic antibodies in the vitreous body]. 61
2170493 1990

Variations for Retina Lymphoma

Expression for Retina Lymphoma

Search GEO for disease gene expression data for Retina Lymphoma.

Pathways for Retina Lymphoma

GO Terms for Retina Lymphoma

Cellular components related to Retina Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immunoglobulin complex, circulating GO:0042571 8.96 IGLL5 IGHV4-38-2
2 external side of plasma membrane GO:0009897 8.8 IGLL5 IGHV4-38-2 CXCR5

Biological processes related to Retina Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.54 IL10 CXCR5 CXCL13
2 positive regulation of B cell activation GO:0050871 9.43 IGLL5 IGHV4-38-2
3 phagocytosis, recognition GO:0006910 9.4 IGLL5 IGHV4-38-2
4 cellular response to lipopolysaccharide GO:0071222 9.33 IL10 CXCL13 BCL10
5 cell chemotaxis GO:0060326 9.32 CXCR5 CXCL13
6 chemokine-mediated signaling pathway GO:0070098 9.26 CXCR5 CXCL13
7 leukocyte chemotaxis GO:0030595 8.96 IL10 CXCR5
8 defense response to bacterium GO:0042742 8.92 IL10 IGLL5 IGHV4-38-2 CXCL13

Molecular functions related to Retina Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immunoglobulin receptor binding GO:0034987 8.62 IGLL5 IGHV4-38-2

Sources for Retina Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....