MCID: RTN014
MIFTS: 47

Retinal Artery Occlusion

Categories: Blood diseases, Cardiovascular diseases, Eye diseases, Neuronal diseases

Aliases & Classifications for Retinal Artery Occlusion

MalaCards integrated aliases for Retinal Artery Occlusion:

Name: Retinal Artery Occlusion 12 54 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:8483
MeSH 44 D015356
NCIt 50 C34978
SNOMED-CT 67 232035005
UMLS 70 C0035302

Summaries for Retinal Artery Occlusion

MalaCards based summary : Retinal Artery Occlusion is related to branch retinal artery occlusion and central retinal artery occlusion, and has symptoms including amaurosis fugax An important gene associated with Retinal Artery Occlusion is APOH (Apolipoprotein H), and among its related pathways/superpathways are p70S6K Signaling and Response to elevated platelet cytosolic Ca2+. The drugs Tenecteplase and Salicylic acid have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and thyroid, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Retinal Artery Occlusion

Diseases in the Retinal Artery Occlusion family:

Central Retinal Artery Occlusion

Diseases related to Retinal Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 637)
# Related Disease Score Top Affiliating Genes
1 branch retinal artery occlusion 32.4 VEGFA SERPINC1 PLG MTHFR F2 CRYAA
2 central retinal artery occlusion 32.1 VEGFA THY1 SERPINC1 PLG MTHFR HMOX1
3 carotid stenosis 31.4 VEGFA MTHFR IL10 ACE
4 amaurosis fugax 31.3 SERPINE1 MTHFR F5
5 retinal vasculitis 31.1 CCL2 APOH ACE
6 carotid artery disease 30.9 PLG CCL2 ACE
7 optic neuritis 30.9 VEGFA IL6 IL10
8 ischemia 30.9 VEGFA PLG HMOX1 ACE
9 eales disease 30.8 VEGFA IL6 IL10
10 infective endocarditis 30.8 SERPINE1 IL6 F2 APOH
11 chorioretinitis 30.8 VEGFA IL6 IL10 ACE
12 transient cerebral ischemia 30.8 MTHFR CCL2 APOH
13 homocystinuria 30.7 SERPINC1 MTHFR F8 F5
14 arteritic anterior ischemic optic neuropathy 30.7 MTHFR F5 F2 ACE
15 retinal detachment 30.7 VEGFA IL6 IL10 CCL2
16 antiphospholipid syndrome 30.7 SERPINE1 SERPINC1 MTHFR F5 F2 APOH
17 central retinal vein occlusion 30.7 VEGFA SERPINC1 MTHFR IL6 F8 F5
18 nonarteritic anterior ischemic optic neuropathy 30.6 VEGFA SERPINC1 MTHFR F5 F2 APOH
19 retinal vascular occlusion 30.6 VEGFB VEGFA SERPINC1 PLG PGF MTHFR
20 polycythemia 30.6 VEGFA SERPINC1 F5 F2 ACE
21 panuveitis 30.6 IL6 IL10 ACE
22 endocarditis 30.6 SERPINE1 SERPINC1 IL6 IL10 F2 APOH
23 carotid artery occlusion 30.6 PLG F8 F5 APOH
24 uveitis 30.6 IL6 IL10 CRYAA CCL2
25 protein s deficiency 30.6 SERPINC1 MTHFR F5 F2 APOH
26 takayasu arteritis 30.5 MTHFR IL6 IL10
27 neuritis 30.5 VEGFA IL6 IL10 CCL2
28 heart valve disease 30.5 F2 APOH ACE
29 rubeosis iridis 30.5 VEGFA PLG
30 thrombophilia 30.5 SERPINE1 SERPINC1 MTHFR F9 F8 F5
31 cavernous sinus thrombosis 30.5 SERPINC1 F2
32 neovascular glaucoma 30.5 VEGFB VEGFA PLG PGF CRYAA
33 iridocyclitis 30.4 VEGFA IL6 IL10 ACE
34 patent foramen ovale 30.4 SERPINE1 SERPINC1 PLG MTHFR F5 F2
35 posterior scleritis 30.4 VEGFA ACE
36 homocysteinemia 30.4 SERPINE1 SERPINC1 MTHFR F5 F2 CCL2
37 rheumatic fever 30.4 IL6 IL10 ACE
38 rheumatic heart disease 30.4 IL6 IL10 ACE
39 atrial heart septal defect 30.4 SERPINC1 PLG MTHFR F2 ACE
40 aortic valve insufficiency 30.3 F2 ACTA2 ACE
41 catastrophic antiphospholipid syndrome 30.3 SERPINE1 MTHFR F5 APOH
42 migraine with aura 30.3 MTHFR F5 F2 ACE
43 ovarian hyperstimulation syndrome 30.3 VEGFA IL6 F5
44 alpha-1-antitrypsin deficiency 30.3 SERPINE1 SERPINC1 F2
45 hemopericardium 30.3 PLG F9 F2
46 migraine with or without aura 1 30.3 PLG MTHFR IL6 IL10 F2 APOH
47 carotid artery thrombosis 30.3 SERPINE1 SERPINC1 PLG
48 compartment syndrome 30.3 SERPINC1 PLG IL6 F8 F2
49 retinal vein occlusion 30.2 VEGFA SERPINE1 SERPINC1 MTHFR IL6 F5
50 thrombocytosis 30.2 SERPINC1 IL6 F2

Graphical network of the top 20 diseases related to Retinal Artery Occlusion:



Diseases related to Retinal Artery Occlusion

Symptoms & Phenotypes for Retinal Artery Occlusion

UMLS symptoms related to Retinal Artery Occlusion:


amaurosis fugax

MGI Mouse Phenotypes related to Retinal Artery Occlusion:

46 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.36 ACE ACTA2 F2 F5 F9 HMOX1
2 homeostasis/metabolism MP:0005376 10.36 ACE APOH F2 F5 F8 F9
3 growth/size/body region MP:0005378 10.29 ACE F2 F5 HMOX1 IL10 IL6
4 immune system MP:0005387 10.25 ACE CCL2 F2 F8 F9 HMOX1
5 mortality/aging MP:0010768 10.2 ACE APOH F2 F5 F8 F9
6 embryo MP:0005380 10.15 ACE F2 F5 F9 HMOX1 IL10
7 liver/biliary system MP:0005370 10.11 ACE F5 F9 HMOX1 IL10 IL6
8 integument MP:0010771 10.06 F2 F5 IL10 IL6 MTHFR PGF
9 reproductive system MP:0005389 9.9 ACE F2 F8 HMOX1 IL10 IL6
10 neoplasm MP:0002006 9.8 ACE IL10 IL6 PGF PLG SERPINE1
11 respiratory system MP:0005388 9.61 F2 HMOX1 IL10 IL6 PGF PLG
12 vision/eye MP:0005391 9.32 ACE ACTA2 IL10 IL6 MTHFR PGF

Drugs & Therapeutics for Retinal Artery Occlusion

Drugs for Retinal Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 30)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tenecteplase Approved Phase 3 191588-94-0
2
Salicylic acid Approved, Investigational, Vet_approved Phase 3 69-72-7 338
3
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
4
Heparin Approved, Investigational Phase 3 9005-49-6 772 9812414
5
Acetazolamide Approved, Vet_approved Phase 3 59-66-5 1986
6 Pharmaceutical Solutions Phase 3
7 Plasminogen Phase 3
8 Tissue Plasminogen Activator Phase 3
9 Analgesics, Non-Narcotic Phase 3
10 Analgesics Phase 3
11 Cyclooxygenase Inhibitors Phase 3
12 Fibrinolytic Agents Phase 3
13 Antirheumatic Agents Phase 3
14 Antipyretics Phase 3
15 Anti-Inflammatory Agents, Non-Steroidal Phase 3
16 Anti-Inflammatory Agents Phase 3
17 Platelet Aggregation Inhibitors Phase 3
18 Neurotransmitter Agents Phase 3
19 Adrenergic Antagonists Phase 3
20 Adrenergic Agents Phase 3
21 Anticoagulants Phase 3
22 Adrenergic beta-Antagonists Phase 3
23 diuretics Phase 3
24 Anticonvulsants Phase 3
25 calcium heparin Phase 3
26 Carbonic Anhydrase Inhibitors Phase 3
27
Regadenoson Approved, Investigational Phase 2 313348-27-5 219024
28
Adenosine Approved, Investigational Phase 2 58-61-7 60961
29
Bevacizumab Approved, Investigational 216974-75-3
30 Ophthalmic Solutions

Interventional clinical trials:

(show all 21)
# Name Status NCT ID Phase Drugs
1 TENecteplase in Central Retinal Artery Occlusion Study (TenCRAOS): A Randomized Placebo-controlled Trial of Early Systemic Tenecteplase Treatment in Patients With Central Retinal Artery Occlusion. Recruiting NCT04526951 Phase 3 Intravenous injection of Tenecteplase and one dose of placebo tablet;One tablet of Acetylsalicylic Acid and one dose of IV placebo
2 A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion Recruiting NCT03197194 Phase 3 Alteplase;acetylsalicylic acid;Placebo Oral Tablet;placebo IV
3 Multizenterstudie Der European Assessment Group for Lysis in the Eye (EAGLE) Zur Behandlung Des Zentralarterienverschlusses (ZAV): Lysetherapie Versus Konservative Therapie Terminated NCT00637468 Phase 3 Intravenous injection of heparin;Intravenous injection of acetazolamide;Topical use of beta-blocker;Isovolaemic haemodilution;Acetylsalicylic acid
4 The Effect of A2A Adrenoceptor Stimulation on the Diameter of Retinal Arterioles During Hypoxia in Vivo Unknown status NCT03090087 Phase 2 Regadenoson
5 The Effect of Transcorneal Stimulation in Cases of Central Retinal Artery Occlusion Using a New Waveform Unknown status NCT00802698 Phase 1, Phase 2
6 Phase 1. Validation and Calibration Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Unknown status NCT01348633
7 Obstructive Sleep Apnea, Retinal Vein Occlusion, Retinal Artery Occlusion Unknown status NCT01291862
8 The Registry of Hyperbaric Oxygen Therapy Treated Patients Unknown status NCT02483650
9 Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning Completed NCT02898480
10 Hemodynamic Computer-assisted Reconstruction of Pathological Changes at the Origin of the Ophthalmic Artery in Patients With Retinal Artery Occlusion Completed NCT02679716
11 Evaluation de la gêne Oculaire après Injections intravitréennes Completed NCT02806830 Optive
12 Transcorneal Electrical Stimulation Therapy for Retinal Disease - A Randomized, Single-blind Pilot Study Completed NCT00804102
13 Study of Arterial Recanalization of the Central Retinal Artery Occlusions Recruiting NCT03049514
14 Pre and Post-arterial Recanalization Imaging of Central Retinal Artery Occlusions (CRAO) Recruiting NCT03313817
15 Evaluation of the Utility of OCT Angiography in Assessing Vascular Perfusion in Rare Retinal and Choroidal Diseases Recruiting NCT02141308
16 A Prospective, Multicenter, Blinded Reading, Self Controlled, Superiority Priority Clinical Trial of Assisted Fundus Image Diagnosis Software for the Diagnosis of Multiple Eye Fundus Diseases Recruiting NCT04723160
17 New Non-invasive Modalities for Assessing Retinal Structure and Function:Preliminary Investigation Recruiting NCT03475173
18 Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion Active, not recruiting NCT03357146
19 Prevalence of Ocular Manifestations in Inflammatory Rheumatic Diseases Active, not recruiting NCT03753893
20 Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study Active, not recruiting NCT02390245
21 Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in the Imaging of Retinovascular Disease Terminated NCT01717937

Search NIH Clinical Center for Retinal Artery Occlusion

Genetic Tests for Retinal Artery Occlusion

Anatomical Context for Retinal Artery Occlusion

MalaCards organs/tissues related to Retinal Artery Occlusion:

40
Eye, Retina, Thyroid, Myeloid, Endothelial, Neutrophil, Pancreas

Publications for Retinal Artery Occlusion

Articles related to Retinal Artery Occlusion:

(show top 50) (show all 1954)
# Title Authors PMID Year
1
Cardiovascular and thrombophilic risk factors in patients with retinal artery occlusion. 54 61
17473572 2007
2
Clinical profile and visual outcome of intraocular inflammation associated with cat-scratch disease in Japanese patients. 61
33797675 2021
3
Diagnostic Yield of Neck CT Angiography in Young Adults With Anterior Circulation Ischemic Stroke: A Community Based Study. 61
33791054 2021
4
The use of multimodal imaging in the evaluation of a patient with central retinal artery occlusion in the setting of asteroid hyalosis: a case report. 61
33794992 2021
5
[OCT-angiography and en-face OCT in paracentral acute middle maculopathy with perivenular ischemia associated with a central retinal artery occlusion]. 61
33637321 2021
6
Multimodal imaging of branch retinal artery occlusion and multiple retinal infiltrates associated to cat's scratch disease. 61
33451868 2021
7
Bilateral retinal artery occlusions as the first manifestation of extramedullary central nervous system involvement in relapsed acute myeloid leukaemia. 61
33811093 2021
8
Central Retinal Artery Occlusion Secondary to Giant Cell Arteritis With Normal Inflammatory Markers. 61
33657589 2021
9
Retrobulbar Spot Sign in Metachronous Bilateral Central Retinal Artery Occlusion of Cardioembolic Origin. 61
32282511 2021
10
Successfully treated hemi-central retinal artery occlusion following cardiac catheterization; case report. 61
33717472 2021
11
BRANCH RETINAL ARTERY WALL RUPTURE AND SUBSEQUENT OCCLUSION DURING PARS PLANA VITRECTOMY WITH MEMBRANE PEEL. 61
30063578 2021
12
Optical coherence tomography-based determination of ischaemia onset - the temporal dynamics of retinal thickness increase in acute central retinal artery occlusion. 61
32767551 2021
13
MULTIMODAL IMAGING IN A CASE OF CENTRAL RETINAL ARTERY OCCLUSION IN THE PRESENCE OF TYPE 2 MACULAR TELANGIECTASIA. 61
29905668 2021
14
Headache in Susac's Syndrome. 61
33738651 2021
15
Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug Formulations. 61
33803405 2021
16
Incidence and Risk of Various Types of Arterial Thromboembolism in Patients With Cancer. 61
33673912 2021
17
Post COVID-19 Ophthalmic Manifestations in an Asian Indian Male. 61
33733987 2021
18
Central Retinal Artery Occlusion in Patients with COVID-19: Imaging for Underlying Causes. 61
33787341 2021
19
Performing hyperbaric oxygen therapy for central retinal artery occlusion under COVID-19: From myringotomy to rapid viral test. 61
33194540 2021
20
Commentary on: Long-Term Outcomes of Ophthalmic and Retinal Artery Occlusion After Cosmetic Facial Filler Injection. 61
33784372 2021
21
Management of Central Retinal Artery Occlusion: A Scientific Statement From the American Heart Association. 61
33677974 2021
22
Workup following retinal artery occlusion-experience from an outpatient retina clinic and the delay in workup. 61
33710475 2021
23
Commentary on: Long-Term Outcomes of Ophthalmic and Retinal Artery Occlusion After Cosmetic Facial Filler Injection. 61
33738465 2021
24
Ischemic stroke and retinal artery occlusion after carotid aneurysm embolization. 61
33488902 2021
25
Usefulness of orbital colour Doppler ultrasound in vascular-related monocular vision loss. 61
33733967 2021
26
ACUTE RETINAL NECROSIS ASSOCIATED WITH HERPES ZOSTER VACCINATION. 61
30048403 2021
27
Vascular Damage May Mimic Retinitis and Optic Neuritis in COVID-19. 61
33661715 2021
28
Case Report: Combined Ischemic Optic Neuropathy and Central Retinal Artery Occlusion after Starting Hemodialysis. 61
33633019 2021
29
Retinal hypoxia and angiogenesis with methamphetamine. 61
33736986 2021
30
Long-Term Outcomes of Ophthalmic and Retinal Artery Occlusion After Cosmetic Facial Filler Injection. 61
33615335 2021
31
Retinal Arteriolar Occlusions and Exudative Retinal Detachments in Malignant Hypertension: More Than Meets the Eye. 61
32840289 2021
32
Management of Acute Central Retinal Artery Occlusion, a "Retinal Stroke": An Institutional Series and Literature Review. 61
33310593 2021
33
Intravitreal sirolimus for persistent, exudative age-related macular degeneration: a Pilot Study. 61
33593448 2021
34
[Intravenous fibrinolysis for nonarteritic central retinal artery occlusion-a treatment option?] 61
33559724 2021
35
The association of aldosterone with papillophlebitis and retinal artery occlusion: A case report. 61
33525896 2021
36
[Branch retinal artery occlusion associated with toxoplasma retinochoroiditis: OCT-angiography findings]. 61
33190964 2021
37
Monocular visual loss as the presenting symptom of COVID-19 infection. 61
33383464 2021
38
Paracentral acute middle maculopathy in the setting of central retinal artery occlusion following COVID-19 diagnosis. 61
33583231 2021
39
Assessment of Trends in the Incidence Rates of Central Retinal Artery Occlusion in Korea From 2002 to 2015. 61
33570556 2021
40
Formation of Transient Retinal Folds Caused by Central Retinal Artery Occlusion After Vitrectomy for Macular Hole Closure. 61
33230069 2021
41
Prepapillary vascular loop-a new classification. 61
32291404 2021
42
Bilateral Central Retinal Artery Occlusion Secondary to SARS-CoV-2 Infection in the Early and Late Periods: A Case Report. 61
33607682 2021
43
Diagnosing Central Retinal Artery Occlusion via Point-of-Care Ultrasound in the Emergency Department. 61
33579659 2021
44
Complete blood cell count measures in retinal artey occlusions. 61
33629472 2021
45
Intra-Arterial Tissue Plasminogen Activator for Central Retinal Artery Occlusion. 61
33623361 2021
46
Paracentral Acute Middle Maculopathy following Surgically Induced Branch Retinal Artery Occlusion During Vitrectomy. 61
33613247 2021
47
Conservative treatments for acute nonarteritic central retinal artery occlusion: Do they work? 61
33767952 2021
48
The Frequency of Carotid Intraplaque Hemorrhage on Vessel Wall Imaging in Patients With Retinal Artery Occlusion: A Cross-Sectional Prevalence Study. 61
33417414 2021
49
The Retrobulbar Spot Sign and Prominent Middle Limiting Membrane as Prognostic Markers in Non-Arteritic Retinal Artery Occlusion. 61
33477523 2021
50
Should we prevent thrombosis related to intravenous immunoglobulin infusions with systematic anticoagulant prophylaxis? 61
32718469 2021

Variations for Retinal Artery Occlusion

Expression for Retinal Artery Occlusion

Search GEO for disease gene expression data for Retinal Artery Occlusion.

Pathways for Retinal Artery Occlusion

Pathways related to Retinal Artery Occlusion according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.93 VEGFB PGF IL6 F2 CCL2 ACE
2
Show member pathways
12.93 VEGFB VEGFA SERPINE1 SERPINC1 PLG F9
3 12.66 VEGFB VEGFA PGF IL6 HMOX1 F2
4
Show member pathways
12.44 PLG IL6 IL10 F2 CCL2
5
Show member pathways
12.07 SERPINE1 PLG MTHFR IL6 F2 CCL2
6 11.82 VEGFA IL6 IL10 HMOX1 CCL2
7 11.77 VEGFA SERPINE1 IL6 HMOX1
8 11.72 VEGFB VEGFA SERPINE1 IL6 CCL2
9
Show member pathways
11.7 SERPINE1 SERPINC1 PLG F9 F8 F5
10 11.64 THY1 IL6 IL10
11 11.56 VEGFA SERPINE1 HMOX1
12 11.53 IL6 HMOX1 CCL2
13 11.42 IL6 IL10 CCL2
14 11.4 IL6 IL10 CCL2
15 11.38 THY1 PLG IL6
16 11.33 SERPINE1 SERPINC1 PLG F9 F8 F5
17 11.21 IL6 IL10 HMOX1
18 11.18 IL6 HMOX1 CCL2
19
Show member pathways
10.78 VEGFB VEGFA PGF
20 10.54 VEGFB VEGFA

GO Terms for Retinal Artery Occlusion

Cellular components related to Retinal Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 10.02 THY1 SERPINE1 SERPINC1 PLG F9 F2
2 extracellular region GO:0005576 9.86 VEGFB VEGFA THY1 SERPINE1 SERPINC1 PLG
3 collagen-containing extracellular matrix GO:0062023 9.8 SERPINE1 SERPINC1 PLG F9 F2 APOH
4 endoplasmic reticulum lumen GO:0005788 9.73 SERPINC1 IL6 F9 F8 F5 F2
5 platelet alpha granule lumen GO:0031093 9.63 VEGFB VEGFA SERPINE1 PLG F8 F5
6 extracellular space GO:0005615 9.55 VEGFB VEGFA SERPINE1 SERPINC1 PLG PGF

Biological processes related to Retinal Artery Occlusion according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.99 VEGFA IL6 IL10 HMOX1 CCL2
2 cellular protein metabolic process GO:0044267 9.96 SERPINC1 PLG IL6 F5 F2
3 positive regulation of protein phosphorylation GO:0001934 9.94 VEGFB VEGFA PGF F2
4 ER to Golgi vesicle-mediated transport GO:0006888 9.93 F9 F8 F5 F2
5 cellular response to lipopolysaccharide GO:0071222 9.93 SERPINE1 IL6 IL10 CCL2
6 negative regulation of neuron apoptotic process GO:0043524 9.91 VEGFB IL10 HMOX1 CCL2
7 response to hypoxia GO:0001666 9.88 VEGFB VEGFA PGF MTHFR HMOX1
8 blood coagulation GO:0007596 9.85 SERPINC1 PLG F9 F8 F5 F2
9 positive regulation of endothelial cell proliferation GO:0001938 9.83 VEGFB VEGFA PGF IL10
10 positive regulation of angiogenesis GO:0045766 9.83 VEGFB VEGFA SERPINE1 PGF HMOX1
11 regulation of blood pressure GO:0008217 9.82 HMOX1 ACTA2 ACE
12 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.82 VEGFB VEGFA PGF
13 angiogenesis GO:0001525 9.8 VEGFB VEGFA THY1 SERPINE1 PGF HMOX1
14 positive regulation of cell division GO:0051781 9.79 VEGFB VEGFA PGF
15 positive chemotaxis GO:0050918 9.79 VEGFB VEGFA PGF
16 acute-phase response GO:0006953 9.77 IL6 F8 F2
17 liver regeneration GO:0097421 9.76 IL6 IL10 HMOX1
18 positive regulation of JAK-STAT cascade GO:0046427 9.75 IL6 IL10 F2
19 sprouting angiogenesis GO:0002040 9.74 VEGFB VEGFA PGF
20 fibrinolysis GO:0042730 9.72 SERPINE1 PLG F2
21 vascular endothelial growth factor signaling pathway GO:0038084 9.71 VEGFB VEGFA PGF
22 induction of positive chemotaxis GO:0050930 9.69 VEGFB VEGFA PGF
23 positive regulation of blood coagulation GO:0030194 9.67 SERPINE1 F2 APOH
24 negative regulation of cell-cell adhesion mediated by cadherin GO:2000048 9.65 VEGFA PLG
25 neutrophil mediated immunity GO:0002446 9.65 IL6 ACE
26 regulation of blood coagulation GO:0030193 9.63 SERPINC1 F2 APOH
27 positive regulation of peptidyl-tyrosine autophosphorylation GO:1900086 9.62 VEGFA ACE
28 blood coagulation, intrinsic pathway GO:0007597 9.62 F9 F8 F2 APOH
29 positive regulation of mast cell chemotaxis GO:0060754 9.58 VEGFB VEGFA PGF
30 platelet degranulation GO:0002576 9.5 VEGFB VEGFA SERPINE1 PLG F8 F5
31 negative regulation of fibrinolysis GO:0051918 9.46 SERPINE1 PLG F2 APOH
32 hemostasis GO:0007599 9.1 SERPINC1 PLG F9 F8 F5 F2

Molecular functions related to Retinal Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.67 VEGFA IL6 IL10 CCL2
2 chemoattractant activity GO:0042056 9.5 VEGFB VEGFA PGF
3 heparin binding GO:0008201 9.43 VEGFB VEGFA SERPINC1 PGF F2 APOH
4 vascular endothelial growth factor receptor binding GO:0005172 9.33 VEGFB VEGFA PGF
5 vascular endothelial growth factor receptor 1 binding GO:0043183 9.26 VEGFB VEGFA
6 growth factor activity GO:0008083 9.1 VEGFB VEGFA PGF IL6 IL10 F2

Sources for Retinal Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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