MCID: RTN014
MIFTS: 46

Retinal Artery Occlusion

Categories: Blood diseases, Cardiovascular diseases, Eye diseases

Aliases & Classifications for Retinal Artery Occlusion

MalaCards integrated aliases for Retinal Artery Occlusion:

Name: Retinal Artery Occlusion 12 54 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8483
MeSH 43 D015356
NCIt 49 C34978
UMLS 71 C0035302

Summaries for Retinal Artery Occlusion

MalaCards based summary : Retinal Artery Occlusion is related to branch retinal artery occlusion and central retinal artery occlusion, and has symptoms including amaurosis fugax An important gene associated with Retinal Artery Occlusion is APOH (Apolipoprotein H), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Pathways in cancer. The drugs Salicylic acid and Acetazolamide have been mentioned in the context of this disorder. Affiliated tissues include eye, heart and brain, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Retinal Artery Occlusion

Diseases in the Retinal Artery Occlusion family:

Central Retinal Artery Occlusion

Diseases related to Retinal Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 567)
# Related Disease Score Top Affiliating Genes
1 branch retinal artery occlusion 33.8 VEGFA SERPINC1 PLG MTHFR FANCG F2
2 central retinal artery occlusion 33.0 VEGFA THY1 SERPINC1 PLG HMOX1 FANCG
3 amaurosis fugax 31.5 SERPINE1 MTHFR F5
4 carotid stenosis 31.4 VEGFA MTHFR ACE
5 optic nerve disease 31.1 VEGFA IL6 CRYAA ACE
6 homocysteinemia 30.9 SERPINE1 SERPINC1 MTHFR F5 F2 APOH
7 heart valve disease 30.8 F2 APOH ACE
8 homocystinuria 30.8 SERPINC1 MTHFR F5
9 arteritic anterior ischemic optic neuropathy 30.7 MTHFR F5 F2 ACE
10 prothrombin-related thrombophilia 30.7 MTHFR F2
11 retinal vascular occlusion 30.7 VEGFB VEGFA SERPINC1 PLG PGF MTHFR
12 chorioretinitis 30.7 VEGFA IL6 IL10 ACE
13 nonarteritic anterior ischemic optic neuropathy 30.7 VEGFA SERPINC1 MTHFR F5 F2 ACE
14 eales disease 30.6 VEGFA IL6 IL10
15 catastrophic antiphospholipid syndrome 30.6 SERPINE1 MTHFR F5 APOH
16 pregnancy loss, recurrent 1 30.6 MTHFR F5 APOH
17 neovascular glaucoma 30.6 VEGFB VEGFA PLG PGF
18 carotid artery occlusion 30.5 PLG F8 F5 APOH
19 cavernous sinus thrombosis 30.5 SERPINC1 F2
20 infective endocarditis 30.5 SERPINE1 IL6 F2 APOH
21 migraine with or without aura 1 30.5 PLG MTHFR IL6 F2 APOH ACE
22 mitral valve stenosis 30.5 SERPINC1 F2 ACE
23 vitreous detachment 30.4 VEGFB VEGFA PLG
24 arteries, anomalies of 30.4 VEGFA SERPINE1 PLG IL6 ACE
25 thrombocytosis 30.4 SERPINC1 IL6 F2
26 endocarditis 30.4 SERPINE1 SERPINC1 IL6 IL10 F2 APOH
27 cryoglobulinemia 30.4 IL6 IL10 APOH
28 retinal vein occlusion 30.4 VEGFA SERPINE1 SERPINC1 MTHFR IL6 F5
29 buerger disease 30.4 SERPINE1 MTHFR F2 APOH
30 exanthem 30.3 VEGFA IL6 IL10 F2 ACE
31 carotid artery thrombosis 30.3 SERPINE1 SERPINC1 PLG
32 rheumatic fever 30.3 IL6 IL10 ACE
33 antiphospholipid syndrome 30.3 SERPINE1 SERPINC1 PGF MTHFR F5 F2
34 rheumatic heart disease 30.3 IL6 IL10 ACE
35 atrial heart septal defect 30.3 SERPINC1 PLG MTHFR F2 ACE
36 takayasu arteritis 30.3 SERPINC1 IL6 IL10 F2 APOH
37 atrial fibrillation 30.3 SERPINC1 IL6 F2 ACE
38 collagen disease 30.2 IL6 IL10 ACE
39 sickle cell anemia 30.2 MTHFR IL6 HMOX1 F2
40 sneddon syndrome 30.2 SERPINC1 F9 F8 F5 F2 APOH
41 protein s deficiency 30.2 SERPINE1 SERPINC1 MTHFR F8 F5 F2
42 coronary heart disease 1 30.2 SERPINE1 MTHFR IL6 ACE
43 budd-chiari syndrome 30.2 SERPINC1 MTHFR F5 F2 APOH
44 patent foramen ovale 30.2 SERPINE1 SERPINC1 PLG MTHFR F5 F2
45 ovarian hyperstimulation syndrome 30.2 VEGFA SERPINC1 IL6 F5
46 aortic aneurysm, familial abdominal, 1 30.2 PLG IL6 ACE
47 arteriosclerosis 30.2 SERPINE1 SERPINC1 IL6 IL10 HMOX1 ACE
48 rubeosis iridis 30.1 VEGFA PLG FANCG
49 atherosclerosis susceptibility 30.1 VEGFA SERPINE1 MTHFR IL6 ACE
50 pericardial effusion 30.1 VEGFA IL6 F2 ACE

Graphical network of the top 20 diseases related to Retinal Artery Occlusion:



Diseases related to Retinal Artery Occlusion

Symptoms & Phenotypes for Retinal Artery Occlusion

UMLS symptoms related to Retinal Artery Occlusion:


amaurosis fugax

MGI Mouse Phenotypes related to Retinal Artery Occlusion:

45 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.36 ACE ACTA2 F2 F5 F9 HMOX1
2 homeostasis/metabolism MP:0005376 10.36 ACE APOH F2 F5 F8 F9
3 growth/size/body region MP:0005378 10.27 ACE F2 F5 HMOX1 IL10 IL6
4 hematopoietic system MP:0005397 10.22 ACE F2 F8 F9 HMOX1 IL10
5 immune system MP:0005387 10.21 ACE F2 F8 F9 HMOX1 IL10
6 mortality/aging MP:0010768 10.2 ACE APOH F2 F5 F8 F9
7 liver/biliary system MP:0005370 10.11 ACE F5 F9 HMOX1 IL10 IL6
8 integument MP:0010771 10.06 F2 F5 IL10 IL6 MTHFR PGF
9 reproductive system MP:0005389 9.93 ACE F2 F8 FANCG HMOX1 IL10
10 neoplasm MP:0002006 9.8 ACE IL10 IL6 PGF PLG SERPINE1
11 respiratory system MP:0005388 9.61 F2 HMOX1 IL10 IL6 PGF PLG
12 vision/eye MP:0005391 9.28 ACTA2 IL10 IL6 MTHFR PGF PLG

Drugs & Therapeutics for Retinal Artery Occlusion

Drugs for Retinal Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Salicylic acid Approved, Investigational, Vet_approved Phase 3 69-72-7 338
2
Acetazolamide Approved, Vet_approved Phase 3 59-66-5 1986
3
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
4
Heparin Approved, Investigational Phase 3 9005-49-6 772 46507594
5 Plasminogen Phase 3
6 Tissue Plasminogen Activator Phase 3
7 Analgesics Phase 3
8 Fibrinolytic Agents Phase 3
9 Platelet Aggregation Inhibitors Phase 3
10 Anti-Inflammatory Agents Phase 3
11 Antipyretics Phase 3
12 Analgesics, Non-Narcotic Phase 3
13 Anticoagulants Phase 3
14 Anti-Inflammatory Agents, Non-Steroidal Phase 3
15 Cyclooxygenase Inhibitors Phase 3
16 Antirheumatic Agents Phase 3
17 calcium heparin Phase 3
18 Carbonic Anhydrase Inhibitors Phase 3
19 Natriuretic Agents Phase 3
20 Anticonvulsants Phase 3
21 diuretics Phase 3
22
Adenosine Approved, Investigational Phase 2 58-61-7 60961
23
Regadenoson Approved, Investigational Phase 2 313348-27-5 219024
24
Bevacizumab Approved, Investigational 216974-75-3
25
Brinzolamide Approved 138890-62-7 68844
26 Ophthalmic Solutions
27 Adrenergic Agonists
28 Adrenergic alpha-2 Receptor Agonists
29 Brimonidine Tartrate 70359-46-5

Interventional clinical trials:

(show all 26)
# Name Status NCT ID Phase Drugs
1 Topical Timolol for the Treatment of Benign Vascular Periocular Lesions Withdrawn NCT01250457 Phase 4 topical Timolol
2 A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion Recruiting NCT03197194 Phase 3 Alteplase;acetylsalicylic acid;Placebo Oral Tablet;placebo IV
3 Multizenterstudie Der European Assessment Group for Lysis in the Eye (EAGLE) Zur Behandlung Des Zentralarterienverschlusses (ZAV): Lysetherapie Versus Konservative Therapie Terminated NCT00637468 Phase 3 Intravenous injection of heparin;Intravenous injection of acetazolamide;Topical use of beta-blocker;Isovolaemic haemodilution;Acetylsalicylic acid
4 The Effect of Transcorneal Stimulation in Cases of Central Retinal Artery Occlusion Using a New Waveform Unknown status NCT00802698 Phase 1, Phase 2
5 The Effect of A2A Adrenoceptor Stimulation on the Diameter of Retinal Arterioles During Hypoxia in Vivo Unknown status NCT03090087 Phase 2 Regadenoson
6 Does Hyperbaric Chamber Improve the Functionality and Symptoms Related to Central Retinal Vein Occlusion (CRVO)? Unknown status NCT02405741 Phase 2
7 Obstructive Sleep Apnea, Retinal Vein Occlusion, Retinal Artery Occlusion Unknown status NCT01291862
8 Phase 1. Validation and Calibration Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Unknown status NCT01348633
9 Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning Completed NCT02898480
10 Transcorneal Electrical Stimulation Therapy for Retinal Disease - A Randomized, Single-blind Pilot Study Completed NCT00804102
11 Evaluation de la gêne Oculaire après Injections intravitréennes Completed NCT02806830 Optive
12 Hemodynamic Computer-assisted Reconstruction of Pathological Changes at the Origin of the Ophthalmic Artery in Patients With Retinal Artery Occlusion Completed NCT02679716
13 Effect of Fixed Brinzolamide-brimonidine Combination on Intraocular Pressure After Phacoemulsification Completed NCT03494257 Brinzolamide-Brimonidine fixed combination
14 A Pilot Study to Determine the Effect on Intraocular Pressure, Optic Nerve Imaging and Other Markers of Venous Congestion of Volunteer Subjects in the Prone Position for a Period of Five Hours Completed NCT00875043
15 Study of Arterial Recanalization of the Central Retinal Artery Occlusions Recruiting NCT03049514
16 New Non-invasive Modalities for Assessing Retinal Structure and Function:Preliminary Investigation Recruiting NCT03475173
17 Investigation of Relevant Biomarkers in Patients With Susac Syndrome Recruiting NCT01273792
18 Pre and Post-arterial Recanalization Imaging of Central Retinal Artery Occlusions (CRAO) Recruiting NCT03313817
19 Spectral-domain Optical Coherence Tomography Findings in Retinal Vessel Occlusion - A Pilot Study of Detecting Ischemia in OCT Recruiting NCT03061526
20 Evaluation of the Utility of OCT Angiography in Assessing Vascular Perfusion in Rare Retinal and Choroidal Diseases Recruiting NCT02141308
21 Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion Active, not recruiting NCT03357146
22 Prevalence of Ocular Manifestations in Inflammatory Rheumatic Diseases Active, not recruiting NCT03753893
23 Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study Active, not recruiting NCT02390245
24 The Registry of Hyperbaric Oxygen Therapy Treated Patients Enrolling by invitation NCT02483650
25 Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in the Imaging of Retinovascular Disease Terminated NCT01717937
26 The Effect of Table Position on Intraocular Pressure (IOP) and Ocular Perfusion Pressure (OPP) During Prone Spine Surgery Terminated NCT00176722

Search NIH Clinical Center for Retinal Artery Occlusion

Genetic Tests for Retinal Artery Occlusion

Anatomical Context for Retinal Artery Occlusion

MalaCards organs/tissues related to Retinal Artery Occlusion:

40
Eye, Heart, Brain, Retina, Kidney, Thyroid, Bone

Publications for Retinal Artery Occlusion

Articles related to Retinal Artery Occlusion:

(show top 50) (show all 1764)
# Title Authors PMID Year
1
Cardiovascular and thrombophilic risk factors in patients with retinal artery occlusion. 54 61
17473572 2007
2
Retinal Vascular Signs and Cerebrovascular Diseases. 61
31977663 2020
3
Comment on: Risk of acute stroke in patients with retinal artery occlusion: a systematic review and meta-analysis. 61
32024973 2020
4
Prevalence of Retinal Emboli and Acute Retinal Artery Occlusion in Acute Ischemic Stroke. 61
31837921 2020
5
Clinical Manifestations and Visual Prognosis of Cilioretinal Artery Sparing Central Retinal Artery Occlusion. 61
32037747 2020
6
Retinal oedema in central retinal artery occlusion develops as a function of time. 61
32040258 2020
7
Ocular Manifestations of Sickle Cell Disease: Signs, Symptoms and Complications. 61
32013659 2020
8
Development of visual acuity under hyperbaric oxygen treatment (HBO) in non arteritic retinal branch artery occlusion. 61
31863398 2020
9
Demonstration of acute retinal ischemia on diffusion weighted magnetic resonance imaging. 61
31816539 2020
10
Symptomatic carotid near-occlusion causes a high risk of recurrent ipsilateral ischemic stroke. 61
31701329 2020
11
Incidence of retinal artery occlusion in Germany. 61
32026572 2020
12
Thrombolytic Therapy for Acute Central Retinal Artery Occlusion. 61
31865896 2020
13
[Central retinal artery occlusion and central retinal vein occlusion after severe contusive trauma: Multimodal imaging]. 61
31987675 2020
14
Long-Standing Retinal Artery Occlusion: OCT Angiography versus Fluorescein Angiography. 61
31902471 2020
15
Characteristics and Outcomes of Retinal Artery Occlusion: Nationally Representative Data. 61
31951154 2020
16
Branch retinal artery occlusion - Finding the culprit! 61
31856513 2020
17
Distal radial access in the anatomical snuffbox for neurointerventions: a feasibility, safety, and proof-of-concept study. 61
31915209 2020
18
UNILATERAL OPTIC NEURITIS AND CENTRAL RETINAL VASCULITIS DUE TO OCULAR SYPHILIS. 61
28816862 2020
19
Using the Retrobulbar Spot Sign to Assist in Diagnosis and Management of Central Retinal Artery Occlusions. 61
31228289 2020
20
Central retinal artery occlusion in a child with angiolymphoid hyperplasia with eosinophilia orbit. 61
31755456 2019
21
Effect of vitrectomy with intrasurgical regulation of intraocular pressure in a rabbit model of central retinal artery occlusion. 61
31626799 2019
22
OPHTHALMIC VASCULAR EVENTS AFTER INTRA-ARTERIAL CHEMOTHERAPY FOR RETINOBLASTOMA: Real-World Comparison Between Primary and Secondary Treatments. 61
30204728 2019
23
Juvenile Central Retinal Artery Occlusion Associated With Atrial Septal Defect. 61
31821511 2019
24
Tick- borne infection revealing human immunodeficiency virus (HIV) positivity in a young adult. 61
31650087 2019
25
Non artheritic bilateral anterior ischaemic optic neuropathy (NAION) as devastating complication following Total Hip Arthroplasty: a case report. 61
31910190 2019
26
Non-invasive current stimulation in vision recovery: a review of the literature. 61
31884495 2019
27
Vision Loss Associated with Hyaluronic Acid Fillers: A Systematic Review of Literature. 61
31822960 2019
28
Prevalence of Atrial Fibrillation in Patients with Retinal Vessel Occlusion and Its Association: A Systematic Review and Meta-Analysis. 61
31283356 2019
29
Bartonella endocarditis masquerading as systemic vasculitis with rapidly progressive glomerulonephritis (aka 'Löhlein nephritis'). 61
31801777 2019
30
Retinal artery occlusion does not portend an increased risk of stroke. 61
31843299 2019
31
Branch retinal artery occlusion in the untreated contralateral eye following aflibercept injections during heparin treatment: Possible contribution of a heparin-induced thrombocytopenia-like condition. 61
31508535 2019
32
Hypothermia protects retinal ganglion cells against hypoxia-induced cell death in a retina organ culture model. 61
31152487 2019
33
Retinal Artery and Vein Occlusions Successfully Treated with Hyperbaric Oxygen. 61
31763582 2019
34
Idiopathic central retinal artery occlusion. 61
31693152 2019
35
Symptomatic Retinal Artery Occlusion after Angioplasty and Stenting of the Carotid Artery: Incidence and Related Risk Factors. 61
31606959 2019
36
Delayed branch retinal artery occlusion in infectious endocarditis. 61
31685405 2019
37
Risk of acute stroke in patients with retinal artery occlusion. 61
31767959 2019
38
Non-arteritic anterior ischemic optic neuropathy with Cilioretinal artery occlusion: a case report. 61
31726996 2019
39
Histopathology of retinoblastoma eyes enucleated after intra-arterial chemotherapy. 61
31676593 2019
40
Association of Retinal Artery Occlusion with Subclinical Coronary Artery Disease. 61
31726494 2019
41
Spontaneous Intra-orbital Arteriovenous Fistula: A Rare Cause of Proptosis. 61
31807372 2019
42
Retinal artery occlusion is associated with compositional and functional shifts in the gut microbiome and altered trimethylamine-N-oxide levels. 61
31653902 2019
43
[Reduced Caliber of the Ophthalmic Artery in Magnetic Resonance Angiography in Patients after Retinal Artery Occlusion]. 61
31652483 2019
44
Ophthalmic and Central Retinal Artery Occlusion Following Triamcinolone Injection of the Lacrimal Gland. 61
31600385 2019
45
Susac Syndrome: A Rare Case Report. 61
31599263 2019
46
[Central retinal artery occlusion secondary to pheochromocytoma]. 61
31182254 2019
47
Can We Restore Vision? A Cadaveric Study Using Hyaluronidase for Retinal Artery Occlusion. 61
31741812 2019
48
Incidence of retinal artery occlusion following intravitreal antivascular endothelial growth factor injections. 61
30810272 2019
49
Seven Points That Explain the Lack of Effect from Reperfusion Therapy in Central Retinal Artery Occlusion. 61
31511166 2019
50
SUDDEN VISION LOSS FROM CENTRAL RETINAL ARTERY OCCLUSION AS A PRESENTING SYMPTOM OF MITRAL VALVE PAPILLARY FIBROELASTOMA. 61
31574007 2019

Variations for Retinal Artery Occlusion

Expression for Retinal Artery Occlusion

Search GEO for disease gene expression data for Retinal Artery Occlusion.

Pathways for Retinal Artery Occlusion

Pathways related to Retinal Artery Occlusion according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.93 VEGFB VEGFA SERPINE1 SERPINC1 PLG F9
2 12.66 VEGFB VEGFA PGF IL6 HMOX1 F2
3
Show member pathways
12.05 SERPINE1 PLG MTHFR IL6 F2
4 11.79 VEGFA IL6 IL10 HMOX1
5 11.74 VEGFA SERPINE1 IL6 HMOX1
6
Show member pathways
11.7 SERPINE1 SERPINC1 PLG F9 F8 F5
7 11.67 VEGFB VEGFA SERPINE1 IL6
8 11.58 THY1 IL6 IL10
9 11.5 VEGFA SERPINE1 HMOX1
10 11.35 THY1 PLG IL6
11 11.33 SERPINE1 SERPINC1 PLG F9 F8 F5
12 11.2 IL6 IL10 HMOX1
13
Show member pathways
10.64 VEGFB VEGFA PGF
14 10.48 VEGFB VEGFA

GO Terms for Retinal Artery Occlusion

Cellular components related to Retinal Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 10.02 THY1 SERPINE1 SERPINC1 PLG F9 F2
2 extracellular region GO:0005576 9.83 VEGFB VEGFA THY1 SERPINE1 SERPINC1 PLG
3 collagen-containing extracellular matrix GO:0062023 9.8 SERPINE1 SERPINC1 PLG F9 F2 APOH
4 endoplasmic reticulum lumen GO:0005788 9.73 SERPINC1 IL6 F9 F8 F5 F2
5 platelet alpha granule lumen GO:0031093 9.63 VEGFB VEGFA SERPINE1 PLG F8 F5
6 extracellular space GO:0005615 9.53 VEGFB VEGFA SERPINE1 SERPINC1 PLG PGF

Biological processes related to Retinal Artery Occlusion according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.96 SERPINC1 PLG IL6 F5 F2
2 ER to Golgi vesicle-mediated transport GO:0006888 9.92 F9 F8 F5 F2
3 positive regulation of protein phosphorylation GO:0001934 9.91 VEGFB VEGFA PGF F2
4 response to hypoxia GO:0001666 9.88 VEGFB VEGFA PGF MTHFR HMOX1
5 angiogenesis GO:0001525 9.88 VEGFB VEGFA THY1 SERPINE1 PGF HMOX1
6 positive regulation of endothelial cell proliferation GO:0001938 9.84 VEGFB VEGFA PGF IL10
7 positive regulation of angiogenesis GO:0045766 9.83 VEGFB VEGFA SERPINE1 PGF HMOX1
8 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.8 VEGFB VEGFA PGF
9 regulation of blood pressure GO:0008217 9.8 HMOX1 ACTA2 ACE
10 blood coagulation GO:0007596 9.8 SERPINC1 PLG F9 F8 F5 F2
11 positive chemotaxis GO:0050918 9.78 VEGFB VEGFA PGF
12 positive regulation of cell division GO:0051781 9.77 VEGFB VEGFA PGF
13 acute-phase response GO:0006953 9.76 IL6 F8 F2
14 sprouting angiogenesis GO:0002040 9.75 VEGFB VEGFA PGF
15 positive regulation of JAK-STAT cascade GO:0046427 9.74 IL6 IL10 F2
16 fibrinolysis GO:0042730 9.72 SERPINE1 PLG F2
17 vascular endothelial growth factor signaling pathway GO:0038084 9.7 VEGFB VEGFA PGF
18 induction of positive chemotaxis GO:0050930 9.69 VEGFB VEGFA PGF
19 positive regulation of blood coagulation GO:0030194 9.67 SERPINE1 F2 APOH
20 negative regulation of cell-cell adhesion mediated by cadherin GO:2000048 9.64 VEGFA PLG
21 neutrophil mediated immunity GO:0002446 9.63 IL6 ACE
22 regulation of blood coagulation GO:0030193 9.63 SERPINC1 F2 APOH
23 positive regulation of peptidyl-tyrosine autophosphorylation GO:1900086 9.59 VEGFA ACE
24 blood coagulation, intrinsic pathway GO:0007597 9.56 F9 F8 F2 APOH
25 positive regulation of mast cell chemotaxis GO:0060754 9.54 VEGFB VEGFA PGF
26 platelet degranulation GO:0002576 9.5 VEGFB VEGFA SERPINE1 PLG F8 F5
27 negative regulation of fibrinolysis GO:0051918 9.46 SERPINE1 PLG F2 APOH
28 hemostasis GO:0007599 9.1 SERPINC1 PLG F9 F8 F5 F2

Molecular functions related to Retinal Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endopeptidase activity GO:0004175 9.54 PLG F9 ACE
2 chemoattractant activity GO:0042056 9.5 VEGFB VEGFA PGF
3 heparin binding GO:0008201 9.43 VEGFB VEGFA SERPINC1 PGF F2 APOH
4 vascular endothelial growth factor receptor binding GO:0005172 9.33 VEGFB VEGFA PGF
5 vascular endothelial growth factor receptor 1 binding GO:0043183 9.26 VEGFB VEGFA
6 growth factor activity GO:0008083 9.1 VEGFB VEGFA PGF IL6 IL10 F2

Sources for Retinal Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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