MCID: RTN004
MIFTS: 20

Retinal Microaneurysm

Categories: Cardiovascular diseases, Eye diseases

Aliases & Classifications for Retinal Microaneurysm

MalaCards integrated aliases for Retinal Microaneurysm:

Name: Retinal Microaneurysm 12 15 73
Microaneurysm 44

Classifications:



External Ids:

Disease Ontology 12 DOID:11295
ICD9CM 35 362.14
MeSH 44 D000071071
SNOMED-CT 68 34037000
UMLS 73 C0154834

Summaries for Retinal Microaneurysm

MalaCards based summary : Retinal Microaneurysm, also known as microaneurysm, is related to vasculopathy, retinal, with cerebral leukodystrophy and macular retinal edema. An important gene associated with Retinal Microaneurysm is BMI1 (BMI1 Proto-Oncogene, Polycomb Ring Finger). The drugs Insulin, Globin Zinc and insulin have been mentioned in the context of this disorder. Affiliated tissues include eye and retina.

Related Diseases for Retinal Microaneurysm

Diseases related to Retinal Microaneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
# Related Disease Score Top Affiliating Genes
1 vasculopathy, retinal, with cerebral leukodystrophy 11.1
2 macular retinal edema 10.5
3 diabetic macular edema 10.3
4 microvascular complications of diabetes 5 10.3
5 polyarteritis nodosa, childhood-onset 10.2
6 polyarteritis nodosa 10.2
7 retinal vein occlusion 10.1
8 hepatitis 10.0
9 hepatitis b 10.0
10 renovascular hypertension 10.0
11 amyloidosis 10.0
12 microscopic polyangiitis 10.0
13 aging 10.0
14 diabetes mellitus 10.0
15 leukemia 10.0
16 chronic leukemia 10.0
17 rheumatoid arthritis 9.9
18 granulomatosis with polyangiitis 9.9
19 arthritis 9.9
20 cerebral hemorrhage 9.9
21 retinal ischemia 9.9
22 thrombosis 9.9
23 glucose intolerance 9.9
24 ehlers-danlos syndrome 9.9
25 retinal vascular disease 9.9
26 ischemia 9.9
27 choriocarcinoma 9.9
28 pneumonia 9.9
29 igg4-related disease 9.9
30 primary angiitis of the central nervous system 9.9
31 head injury 9.9

Comorbidity relations with Retinal Microaneurysm via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Retinal Microaneurysm:



Diseases related to Retinal Microaneurysm

Symptoms & Phenotypes for Retinal Microaneurysm

Drugs & Therapeutics for Retinal Microaneurysm

Drugs for Retinal Microaneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Insulin, Globin Zinc Phase 4
2 insulin Phase 4
3 Hypoglycemic Agents Phase 4
4
Dopamine Approved Phase 2 51-61-6, 62-31-7 681
5
Ranibizumab Approved Phase 2 347396-82-1 459903
6
Sulpiride Approved, Investigational Phase 2 15676-16-1 5355
7 Sympathomimetics Phase 2
8 Central Nervous System Depressants Phase 2
9 Dopamine Agents Phase 2
10 Peripheral Nervous System Agents Phase 2
11 Antidepressive Agents Phase 2
12 Antipsychotic Agents Phase 2
13 Psychotropic Drugs Phase 2
14 Dopamine Antagonists Phase 2
15 Antidepressive Agents, Second-Generation Phase 2
16 Immunologic Factors Phase 2
17 Angiogenesis Inhibitors Phase 2
18 Angiogenesis Modulating Agents Phase 2
19 Neurotransmitter Agents Phase 2
20 Tranquilizing Agents Phase 2
21 Hormones Phase 2
22 Cardiotonic Agents Phase 2
23 Protective Agents Phase 2
24 Autonomic Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 CPAP Effect on the Progression of Diabetic Retinopathy in Patients With Sleep Apnea Recruiting NCT02874313 Phase 4 Pharmacological treatment
2 Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema Recruiting NCT03161652 Phase 2 DME lactose pill;DME levosulpiride;DR lactose pill;DR levosulpiride;DR vitrectomy lactose pill;DR vitrectomy levosulpiride;DME plus ranibizumab lactose pill;DME plus ranibizumab levosulpiride

Search NIH Clinical Center for Retinal Microaneurysm

Cochrane evidence based reviews: microaneurysm

Genetic Tests for Retinal Microaneurysm

Anatomical Context for Retinal Microaneurysm

MalaCards organs/tissues related to Retinal Microaneurysm:

41
Eye, Retina

Publications for Retinal Microaneurysm

Articles related to Retinal Microaneurysm:

(show top 50) (show all 61)
# Title Authors Year
1
Clinical Report Guided Retinal Microaneurysm Detection With Multi-Sieving Deep Learning. ( 29727278 )
2018
2
Structural and Functional Analyses of Retinal Ischemia in Eyes with Retinal Vein Occlusion: Relationship with Macular Edema or Microaneurysm Formation. ( 30359965 )
2018
3
Estimation of Diabetic Retinal Microaneurysm Perfusion Parameters Based on Computational Fluid Dynamics Modeling of Adaptive Optics Scanning Laser Ophthalmoscopy. ( 30245632 )
2018
4
Six-month results of intravitreal ranibizumab for macular edema after branch retinal vein occlusion in a single-center prospective study: visual outcomes and microaneurysm formation. ( 30154646 )
2018
5
Microaneurysm turnover is a predictor of diabetic retinopathy progression. ( 29699981 )
2018
6
Statistical Geometrical Features for Microaneurysm Detection. ( 28785874 )
2018
7
Recurrent infectious subcapsular renal hematoma accompanied by microaneurysm. ( 29344911 )
2018
8
Microaneurysm detection using fully convolutional neural networks. ( 29544784 )
2018
9
Microaneurysm Detection Using Principal Component Analysis and Machine Learning Methods. ( 29994317 )
2018
10
Fusion of Deep Convolutional Neural Networks for Microaneurysm Detection in Color Fundus Images. ( 30441176 )
2018
11
Cellular Senescence Is Associated With Human Retinal Microaneurysm Formation During Aging. ( 28570738 )
2017
12
Ensemble based adaptive over-sampling method for imbalanced data learning in computer aided detection of microaneurysm. ( 27507324 )
2017
13
Vessel segmentation and microaneurysm detection using discriminative dictionary learning and sparse representation. ( 28187898 )
2017
14
Spontaneous Rupture and Involution of a "Macro-Microaneurysm" in Diabetic Retinopathy. ( 28196055 )
2017
15
Hemorrhage and/or Microaneurysm Severity and Count in Ultrawide Field Images and Early Treatment Diabetic Retinopathy Study Photography. ( 28336057 )
2017
16
Automated microaneurysm detection in diabetic retinopathy using curvelet transform. ( 26868326 )
2016
17
Renal Artery Microaneurysm in a Woman With Amyloidosis. ( 26921752 )
2016
18
Effects of sub-Tenon's capsule triamcinolone acetonide injection combined with microaneurysm photocoagulation on diabetic macular edema. ( 26675141 )
2015
19
Microaneurysm count as a predictor of long-term progression in diabetic retinopathy in young patients with type 1 diabetes: the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987). ( 24898428 )
2015
20
Ruptured Cerebral Microaneurysm Diagnosed by 3-Dimensional Fast Spin-Echo T1 Imaging with Variable Flip Angles. ( 26009499 )
2015
21
Using a multi-agent system approach for microaneurysm detection in fundus images. ( 24423809 )
2014
22
Microaneurysm formation in an intercostal artery--a possible mechanism for intramural hematoma of the distal thoracic aorta. ( 24461976 )
2014
23
Microaneurysm turnover in diabetic retinopathy assessed by automated RetmarkerDR image analysis--potential role as biomarker of response to ranibizumab treatment. ( 24662930 )
2014
24
Retinal microaneurysm detection through local rotating cross-section profile analysis. ( 23192523 )
2013
25
Imaging of laser-photocoagulated diabetic microaneurysm with spectral domain optical coherence tomography. ( 23478291 )
2013
26
Improving microaneurysm detection in color fundus images by using context-aware approaches. ( 23746595 )
2013
27
Automated microaneurysm detection method based on Eigenvalue analysis using Hessian matrix in retinal fundus images. ( 24111075 )
2013
28
An ensemble-based system for microaneurysm detection and diabetic retinopathy grading. ( 22481810 )
2012
29
Retinal microaneurysm count predicts progression and regression of diabetic retinopathy. Post-hoc results from the DIRECT Programme. ( 21309844 )
2011
30
Role of intracranial microaneurysm in the pathogenesis of stroke in SHR-SP. ( 22117803 )
2011
31
Microaneurysm detection with radon transform-based classification on retina images. ( 22255692 )
2011
32
Evaluation of the grading performance of an ensemble-based microaneurysm detector. ( 22255693 )
2011
33
Repetitive stent fractures with diffuse coronary artery microaneurysm formation--sirolimus eluting stent hypersensitivity? ( 22649895 )
2011
34
Microaneurysm number and distribution in the macula of Chinese type 2 diabetics with early diabetic retinopathy: a population-based study in Kinmen, Taiwan. ( 19183838 )
2010
35
Experience with microaneurysm formation at the basilar terminus in the rabbit elastase aneurysm model. ( 19797794 )
2010
36
Computer-assisted microaneurysm turnover in the early stages of diabetic retinopathy. ( 19372722 )
2009
37
Microaneurysm turnover is a biomarker for diabetic retinopathy progression to clinically significant macular edema: findings for type 2 diabetics with nonproliferative retinopathy. ( 19372723 )
2009
38
Correlation between microaneurysm closure rate and reduction in macular thickness following laser photocoagulation of diabetic macular edema. ( 17417620 )
2008
39
Retina lesion and microaneurysm segmentation using morphological reconstruction methods with ground-truth data. ( 19163946 )
2008
40
Three-dimensional analysis of pathological characteristics of a microaneurysm. ( 17416106 )
2007
41
An automated microaneurysm detector as a tool for identification of diabetic retinopathy in rural optometric practice. ( 16907667 )
2006
42
Automated microaneurysm detection using local contrast normalization and local vessel detection. ( 16967807 )
2006
43
Rupture of a saccular microaneurysm of the supraclinoid internal carotid artery after mild head injury in a case with prominent posterior clinoid process. ( 17114872 )
2006
44
Automated measurement of microaneurysm turnover. ( 14638735 )
2003
45
Glomerular lesions in male rabbits treated with aluminium lactate: with special reference to microaneurysm formation. ( 10965988 )
2000
46
The application of wavelets to retinal image compression and its effect on automatic microaneurysm analysis. ( 9617522 )
1998
47
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. ( 9211853 )
1997
48
A fully automated comparative microaneurysm digital detection system. ( 9474307 )
1997
49
Retinal microaneurysm counts and 10-year progression of diabetic retinopathy. ( 7487599 )
1995
50
Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients. ( 7742285 )
1995

Variations for Retinal Microaneurysm

Expression for Retinal Microaneurysm

Search GEO for disease gene expression data for Retinal Microaneurysm.

Pathways for Retinal Microaneurysm

GO Terms for Retinal Microaneurysm

Sources for Retinal Microaneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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