MCID: RTN004
MIFTS: 17

Retinal Microaneurysm

Categories: Eye diseases

Aliases & Classifications for Retinal Microaneurysm

MalaCards integrated aliases for Retinal Microaneurysm:

Name: Retinal Microaneurysm 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11295
ICD9CM 35 362.14
SNOMED-CT 68 193363005 34037000
UMLS 73 C0154834

Summaries for Retinal Microaneurysm

MalaCards based summary : Retinal Microaneurysm is related to retinitis and microvascular complications of diabetes 5. An important gene associated with Retinal Microaneurysm is BMI1 (BMI1 Proto-Oncogene, Polycomb Ring Finger). The drugs Hypoglycemic Agents and insulin have been mentioned in the context of this disorder. Affiliated tissues include eye.

Related Diseases for Retinal Microaneurysm

Diseases related to Retinal Microaneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 retinitis 10.4
2 microvascular complications of diabetes 5 10.2
3 aging 9.9

Comorbidity relations with Retinal Microaneurysm via Phenotypic Disease Network (PDN):


Hypertension, Essential

Symptoms & Phenotypes for Retinal Microaneurysm

Drugs & Therapeutics for Retinal Microaneurysm

Drugs for Retinal Microaneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Hypoglycemic Agents Phase 4
2 insulin Phase 4
3 Insulin, Globin Zinc Phase 4
4
Dopamine Approved Phase 2 51-61-6, 62-31-7 681
5
Ranibizumab Approved Phase 2 347396-82-1 459903
6
Sulpiride Approved, Investigational Phase 2 15676-16-1 5355
7 Angiogenesis Inhibitors Phase 2
8 Angiogenesis Modulating Agents Phase 2
9 Antidepressive Agents Phase 2
10 Antidepressive Agents, Second-Generation Phase 2
11 Antipsychotic Agents Phase 2
12 Autonomic Agents Phase 2
13 Central Nervous System Depressants Phase 2
14 Dopamine Agents Phase 2
15 Dopamine Antagonists Phase 2
16 Hormones Phase 2
17 Neurotransmitter Agents Phase 2
18 Peripheral Nervous System Agents Phase 2
19 Protective Agents Phase 2
20 Psychotropic Drugs Phase 2
21 Tranquilizing Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 CPAP Effect on the Progression of Diabetic Retinopathy in Patients With Sleep Apnea Recruiting NCT02874313 Phase 4 Pharmacological treatment
2 Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema Recruiting NCT03161652 Phase 2 DME lactose pill;DME levosulpiride;DR lactose pill;DR levosulpiride;DR vitrectomy lactose pill;DR vitrectomy levosulpiride;DME plus ranibizumab lactose pill;DME plus ranibizumab levosulpiride

Search NIH Clinical Center for Retinal Microaneurysm

Genetic Tests for Retinal Microaneurysm

Anatomical Context for Retinal Microaneurysm

MalaCards organs/tissues related to Retinal Microaneurysm:

41
Eye

Publications for Retinal Microaneurysm

Articles related to Retinal Microaneurysm:

# Title Authors Year
1
Clinical Report Guided Retinal Microaneurysm Detection With Multi-Sieving Deep Learning. ( 29727278 )
2018
2
Cellular Senescence Is Associated With Human Retinal Microaneurysm Formation During Aging. ( 28570738 )
2017
3
Retinal microaneurysm detection through local rotating cross-section profile analysis. ( 23192523 )
2013
4
Retinal microaneurysm count predicts progression and regression of diabetic retinopathy. Post-hoc results from the DIRECT Programme. ( 21309844 )
2011
5
Retinal microaneurysm counts and 10-year progression of diabetic retinopathy. ( 7487599 )
1995
6
Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients. ( 7742285 )
1995
7
The relationship of retinal microaneurysm counts to the 4-year progression of diabetic retinopathy. ( 2597068 )
1989
8
Retinal microaneurysm counts in diabetic retinopathy: colour photography versus fluorescein angiography. ( 3607597 )
1987
9
Studies on chronic carbon disulfide poisoning. Pathogenesis of retinal microaneurysm due to carbon disulfide, with special reference to a subclinical defect of carbohydrate metabolism. ( 5570047 )
1971
10
Dissimilarity of retinal microaneurysm and glomerular nodule in diabetes. ( 13354059 )
1956

Variations for Retinal Microaneurysm

Expression for Retinal Microaneurysm

Search GEO for disease gene expression data for Retinal Microaneurysm.

Pathways for Retinal Microaneurysm

GO Terms for Retinal Microaneurysm

Sources for Retinal Microaneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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