Aliases & Classifications for Retinitis

MalaCards integrated aliases for Retinitis:

Name: Retinitis 12 54 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3612
MeSH 43 D012173
NCIt 49 C115993
SNOMED-CT 67 35426003
ICD10 32 H30.9
UMLS 71 C0035333

Summaries for Retinitis

MalaCards based summary : Retinitis is related to bothnia retinal dystrophy and retinitis pigmentosa 50. An important gene associated with Retinitis is RPGR (Retinitis Pigmentosa GTPase Regulator), and among its related pathways/superpathways are Metabolism of fat-soluble vitamins and Visual Cycle in Retinal Rods. The drugs Sodium citrate and Ranibizumab have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and bone, and related phenotypes are Decreased HPV16-GFP infection and nervous system

Related Diseases for Retinitis

Diseases related to Retinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 2791)
# Related Disease Score Top Affiliating Genes
1 bothnia retinal dystrophy 34.5 RLBP1 PRPH2
2 retinitis pigmentosa 50 34.5 RPGR PRPH2 EYS
3 late-onset retinal degeneration 34.4 RPGR RHO EYS
4 retinitis pigmentosa 35 34.2 SEMA4A RPGR
5 retinitis pigmentosa 25 34.2 RPGR PRPH2 PDE6A EYS
6 hereditary retinal dystrophy 34.1 RPE65 RHO EYS
7 retinitis pigmentosa 26 34.0 RPGR CERKL
8 retinal perforation 34.0 RPE65 RLBP1
9 retinitis pigmentosa 29 33.9 PDE6A FAM161A CERKL
10 retinitis pigmentosa 6 33.8 RPGR RP9
11 retinitis pigmentosa 4 33.7 RPGR RP9 RHO
12 retinitis pigmentosa 20 33.7 RPGR RPE65 RP9
13 retinitis pigmentosa 19 33.6 RPGR RP9
14 retinitis pigmentosa 34 33.6 RPGR RP9
15 retinitis pigmentosa 14 33.6 RPGR RP9 CERKL
16 retinitis pigmentosa 54 33.6 RP9 FAM161A
17 retinitis pigmentosa 7 33.5 RPGR RP9 PRPH2 PDE6A
18 retinitis pigmentosa 17 33.5 RPGR RP9
19 usher syndrome, type i 33.5 RPGR RPE65 RHO IMPDH1
20 retinitis pigmentosa 10 33.4 RPGR RP9 IMPDH1
21 retinal ciliopathy 33.3 RPGRIP1 RPGR RP1
22 retinitis pigmentosa 3 33.3 RPGRIP1 RPGR RP9 RP2
23 retinoschisis 1, x-linked, juvenile 33.3 RPGR RPE65 RHO
24 enhanced s-cone syndrome 33.2 RPGR RPE65 RHO
25 usher syndrome 33.1 RPGR RPE65 RHO PRPH2 PDE6A EYS
26 retinitis pigmentosa 1 33.1 RP1 RHO PRPH2 PRPF3 PDE6A IMPDH1
27 peripheral retinal degeneration 33.1 RPGR RLBP1 RHO PRPH2 IMPDH1 CERKL
28 senior-loken syndrome 1 33.1 RPGRIP1 RPGR RPE65 IMPDH1
29 bestrophinopathy, autosomal recessive 33.0 RPE65 RLBP1 PRPH2
30 leber congenital amaurosis 3 33.0 RPGRIP1 RPE65 IMPDH1
31 retinitis pigmentosa 33 33.0 SNRNP200 RP9 PRPF3
32 fundus albipunctatus 33.0 RPGR RPE65 RLBP1 RHO PRPH2 CERKL
33 macular degeneration, age-related, 1 33.0 RPGR RPE65 RLBP1 RHO PRPH2 FLVCR1
34 retinitis pigmentosa 9 32.9 RP9 PRPF3 IMPDH1
35 retinitis pigmentosa 13 32.9 SNRNP200 RPGR RP9 PRPF3
36 pattern dystrophy 32.9 RP2 RHO PRPH2
37 leber congenital amaurosis 4 32.8 RPGRIP1 RPE65 PRPH2 PDE6A IMPDH1
38 cone-rod dystrophy 6 32.8 RPGRIP1 RPGR RPE65 PRPH2 PDE6A CERKL
39 vitelliform macular dystrophy 32.8 RPGR RPE65 PRPH2
40 retinitis pigmentosa 63 32.8 SNRNP200 PRPF3 KLHL7 IMPDH1
41 cone dystrophy 32.7 RPGR RPE65 RLBP1 RHO PRPH2 EYS
42 newfoundland rod-cone dystrophy 32.7 RLBP1 RHO PRPH2
43 solar retinopathy 32.7 RLBP1 RHO
44 inherited retinal disorder 32.7 RPGR RPE65 RP2 RP1 PRPH2 FAM161A
45 leber congenital amaurosis 1 32.6 RPGRIP1 RPE65 RP1 RHO PRPH2 IMPDH1
46 retinitis pigmentosa 31 32.5 TOPORS RP9 PRPF3 IMPDH1
47 cone-rod dystrophy 1 32.5 RPGRIP1 RPGR
48 preretinal fibrosis 32.5 RLBP1 FLVCR1
49 eye disease 32.4 RPGR RPE65 RLBP1 RHO PRPH2
50 yemenite deaf-blind hypopigmentation syndrome 32.4 RPGR RPE65 RHO

Graphical network of the top 20 diseases related to Retinitis:



Diseases related to Retinitis

Symptoms & Phenotypes for Retinitis

GenomeRNAi Phenotypes related to Retinitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased HPV16-GFP infection GR00350-A 8.92 FLVCR1 IMPDH1 RP2 RPE65

MGI Mouse Phenotypes related to Retinitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.93 FAM161A PDE6A PRPH2 RHO RLBP1 RP1
2 pigmentation MP:0001186 9.5 PRPF3 PRPH2 RHO RLBP1 RPE65 RPGR
3 vision/eye MP:0005391 9.5 CERKL FAM161A IMPDH1 PDE6A PRPF3 PRPH2

Drugs & Therapeutics for Retinitis

Drugs for Retinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 223)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sodium citrate Approved, Investigational Phase 4 68-04-2
2
Ranibizumab Approved Phase 4 347396-82-1 459903
3
Pancrelipase Approved, Investigational Phase 4 53608-75-6
4
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
5 Sildenafil Citrate Phase 4 171599-83-0
6 Citrate Phase 4
7 Antibodies Phase 4
8 Immunoglobulins Phase 4
9 Gastrointestinal Agents Phase 4
10 Angiogenesis Inhibitors Phase 4
11 Autoantibodies Phase 4
12 Vardenafil Dihydrochloride Phase 4
13 Vasodilator Agents Phase 4
14 Phosphodiesterase Inhibitors Phase 4
15 Phosphodiesterase 5 Inhibitors Phase 4
16 pancreatin Phase 4
17
Eplerenone Approved Phase 2, Phase 3 107724-20-9 150310 443872
18
Sargramostim Approved, Investigational Phase 3 123774-72-1, 83869-56-1
19
Tocopherol Approved, Investigational Phase 3 1406-66-2, 54-28-4 14986
20
Acyclovir Approved Phase 3 59277-89-3 2022
21
Ganciclovir Approved, Investigational Phase 2, Phase 3 82410-32-0 3454
22
Valganciclovir Approved, Investigational Phase 2, Phase 3 175865-60-8 64147
23
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 68-26-8, 11103-57-4, 22737-96-8 445354 9904001
24
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
25
Lutein Approved, Investigational, Nutraceutical Phase 3 127-40-2 6433159
26
Vitamin D Approved, Nutraceutical, Vet_approved Phase 3 1406-16-2
27 Tocotrienol Investigational Phase 3 6829-55-6
28 Hormone Antagonists Phase 2, Phase 3
29 Hormones Phase 2, Phase 3
30 Mineralocorticoids Phase 2, Phase 3
31 Mineralocorticoid Receptor Antagonists Phase 2, Phase 3
32 Natriuretic Agents Phase 2, Phase 3
33 Diuretics, Potassium Sparing Phase 2, Phase 3
34 diuretics Phase 2, Phase 3
35 Immunologic Factors Phase 3
36 Antibodies, Monoclonal Phase 2, Phase 3
37 Antineoplastic Agents, Immunological Phase 2, Phase 3
38 retinol Phase 3
39 Retinol palmitate Phase 3
40 Tocopherols Phase 3
41 Tocotrienols Phase 3
42 Calciferol Phase 3
43 Antiviral Agents Phase 2, Phase 3
44 Anti-Infective Agents Phase 2, Phase 3
45 Ganciclovir triphosphate Phase 2, Phase 3
46 Antihypertensive Agents Phase 3
47 Isopropyl unoprostone Phase 3
48
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
49
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2 1177-87-3
50
Nelfinavir Approved Phase 2 159989-64-7 64143

Interventional clinical trials:

(show top 50) (show all 261)
# Name Status NCT ID Phase Drugs
1 A Prospective, Randomized, 3-arm Parallel Trial to Evaluate the Safety and Clinical Effectiveness of 2 Lower Dose Combined PDE5i's vs. Single Maximal Dose PDE5i Treatment Unknown status NCT00498680 Phase 4 Sildenafil, Vardenafil;Sildenafil;Vardenafil;Sildenafil & Vardenafil
2 Role of Capsular Tension Ring in Anterior Capsular Contraction in Retinitis Pigmentosa Patients Completed NCT00717080 Phase 4
3 A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium) Completed NCT00002125 Phase 4 Foscarnet sodium
4 Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Completed NCT00000894 Phase 4 Cidofovir;Probenecid;Ganciclovir
5 Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Completed NCT01866397 Phase 4
6 Use of Cidofovir Injection in the Treatment of Recurrent Respiratory Papillomatosis." Completed NCT00205374 Phase 4 Cidofovir;Placebo
7 Correlation of Functional and Structural Outcomes With Serum Antibody Profiles in Patients With Neovascular Age-related Macular Degeneration Treated With Ranibizumab and Healthy Subjects: A Prospective, Controlled Monocenter Trial Completed NCT02843490 Phase 4 Ranibizumab
8 Open, Randomised Study Comparing Preemptive Therapy With Intravenous Ganciclovir With and Without Additional Oral Ganciclovir for CMV Prophylaxis in Immunosuppressed Renal Transplant Patients Receiving Monitoring of CMV Viral Load Completed NCT00373165 Phase 4 Ganciclovir
9 Pharmacokinetics of Valganciclovir in Kidney and Kidney/Pancreas Transplant Recipients Completed NCT00034385 Phase 4 Valganciclovir
10 An Integrated Approach With Vardenafil Orodispersible and Cognitive-behavioral Sex Therapy for the Treatment of Erectile Dysfunction (STEDOV) Completed NCT02450188 Phase 4 Vardenafil
11 Open-Label Safety Study of Valganciclovir in Patients With CMV Retinitis and AIDS Who Have Complications Due to IV Treatment Unknown status NCT00017784 Phase 3 Valganciclovir
12 A Randomized, Double-masked, Placebo Controlled Study of the Beneficial Effects of Eplerenone on Central Serous Chorioretinopathy Unknown status NCT02215330 Phase 2, Phase 3 Eplerenone;Maltodextrin
13 Foscarnet-Ganciclovir CMV Retinitis Trial Completed NCT00000136 Phase 3 Foscarnet;Ganciclovir
14 A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00000688 Phase 3 Ganciclovir
15 Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis Completed NCT00002070 Phase 3 Sargramostim;Ganciclovir
16 A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Completed NCT00002377 Phase 3 Valganciclovir;Ganciclovir
17 Cytomegalovirus Retinitis Retreatment Trial Completed NCT00000134 Phase 3 Ganciclovir;Foscarnet
18 Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) Completed NCT00000142 Phase 2, Phase 3 Cidofovir
19 Monoclonal Antibody CMV Retinitis Trial (MACRT) Completed NCT00000135 Phase 2, Phase 3 MSL-109
20 A Treatment Protocol for the Use of Intravenous Ganciclovir in AIDS Patients With Immediately Sight-Threatening CMV Retinitis Completed NCT00000698 Phase 3 Ganciclovir
21 Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Completed NCT00000143 Phase 3 Cidofovir intravenous
22 Ganciclovir Implant Study for Cytomegalovirus Retinitis Completed NCT00000118 Phase 3
23 Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa Completed NCT00000114 Phase 3 Vitamin E;Vitamin A
24 Randomized Clinical Trial for Retinitis Pigmentosa Completed NCT00346333 Phase 3 Lutein
25 Randomized Trial for Retinitis Pigmentosa Completed NCT00000116 Phase 3 Vitamin A;Nutritional Supplement
26 A Phase III, Prospective, Randomized, Double-Blind Trial of Valganciclovir Pre-Emptive Therapy for Cytomegalovirus (CMV) Viremia as Detected by Plasma CMV DNA PCR Assay Completed NCT00006145 Phase 3 Valganciclovir
27 An Investigator Initiated Prospective Randomized, Controlled Pilot Study in Order to Evaluate the Place of Valganciclovir in Prevention of Cytomegalovirus Reactivation Following Allogeneic Stem Cell Transplantation Completed NCT00330018 Phase 3 Valganciclovir;Acyclovir
28 A Dose Escalation (Phase 1), and Dose Expansion (Phase 2/3) Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using an Adeno-Associated Viral Vector (AAV8) Encoding Retinitis Pigmentosa GTPase Regulator (RPGR) Recruiting NCT03116113 Phase 2, Phase 3
29 The Effect of Oral Administration of 9-cis β Carotene Rich Powder of the Alga Dunaliella Bardawil on Visual Functions in Patients With Retinitis Pigmentosa Recruiting NCT01680510 Phase 2, Phase 3
30 Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis: Treatment Recruiting NCT03586284 Phase 2, Phase 3 Valganciclovir Hydrochloride;Ganciclovir Sodium;Placebo Oral Tablet;Topical placebo
31 A Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis (LCA) Using Adeno-Associated Viral Vector to Deliver the Gene for Human RPE65 to the Retinal Pigment Epithelium (RPE) [AAV2-hRPE65v2-301] Active, not recruiting NCT00999609 Phase 3
32 Phase III Clinical Study of UF-021 for Retinitis Pigmentosa - Evaluation for a Comparative Double Masked Placebo Controlled Study Period and a Continuous Administration Period Terminated NCT01786395 Phase 3 UF-021;Placebo
33 Argus® II Retinal Stimulation System Feasibility Protocol Unknown status NCT00407602 Phase 2
34 An Open Labeled Clinical Study to Evaluate the Safety and Efficacy OF Autologous Bone Marrow Derived Mono Nuclear Stem Cell (BMMNCs) in Retinitis Pigmentosa. It is Self Funded (Patients' Own Funding) Clinical Trial Unknown status NCT01914913 Phase 1, Phase 2
35 Prospective Non-randomised Exploratory Study to Assess the Safety and Efficacy of Aflibercept (Eylea) in Cystoid Macular Oedema (CMO) Associated With Retinitis Pigmentosa (RP) Unknown status NCT02661711 Phase 2 Aflibercept
36 Dexamethasone in Retinitis Pigmentosa Cystoid Macular Edema Unknown status NCT02804360 Phase 2
37 A Phase II, Randomized, Placebo-Controlled Study to Determine the Effects of Viracept on the Clinical Outcome of Cytomegalovirus (CMV) Retinitis in AIDS Patients Who Are Receiving Standard Induction and Maintenance Therapy for This Infection Completed NCT00002169 Phase 2 Nelfinavir mesylate
38 Nerve Growth Factor Eye Drops as a Novel Treatment for Vision Loss in Patients With Retinitis Pigmentosa: From Preclinical to Clinical Phase II Trial Completed NCT02609165 Phase 2 rhNGF 180 µg/ml eye drops solution;vehicle eye drops
39 Efficacy and Safety of Oral Valproic Acid for Retinitis Pigmentosa Completed NCT01399515 Phase 2 Valproic Acid
40 A Phase II/III Study of the Safety and Efficacy of 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) for the Treatment of Peripheral Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00002437 Phase 2 Cidofovir;Probenecid
41 A Phase II/III Trial of Human Anti-CMV Monoclonal Antibody MSL 109 (MACRT) Completed NCT00000836 Phase 2 Sevirumab
42 An Exploratory Study to Evaluate the Safety of Brimonidine Intravitreal Implant in Patients With Retinitis Pigmentosa Completed NCT00661479 Phase 1, Phase 2 400 µg Brimonidine Tartrate Implant;200 µg Brimonidine Tartrate Implant;100 µg Brimonidine Tartrate Implant
43 CMV Retinitis Retreatment Trial Completed NCT00000766 Phase 2 Foscarnet sodium;Ganciclovir
44 An Open-Label Study of the Safety and Efficacy of Intravitreal ISIS 2922 in Acquired Immune Deficiency Syndrome (AIDS) Patients With Cytomegalovirus Retinitis (NOTE: Restricted to Patients Who Rollover From Another Controlled ISIS 2922 Trial) Completed NCT00002356 Phase 2 Fomivirsen sodium
45 A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR ) Completed NCT00002156 Phase 2 Fomivirsen sodium;Ganciclovir
46 A Phase II Multiple Site, Randomized, Placebo-Controlled Trial of Oral Valproic Acid for Autosomal Dominant Retinitis Pigmentosa Completed NCT01233609 Phase 2 Valproic Acid;Placebo
47 Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis Completed NCT00004794 Phase 2 cidofovir
48 A Prospective, Multicenter, Open-Label, Single-Arm Study of the Safety and Tolerability of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa (RP) Completed NCT02320812 Phase 1, Phase 2
49 A Phase II, Double-Masked, Randomized, Placebo-Controlled Evaluation of Standard Therapy vs. Standard Therapy Combined With Human Monoclonal Anti-Cytomegalovirus Antibody (MSL 109) in the Therapy of AIDS Patients With Cytomegalovirus (CMV) Retinitis Completed NCT00001061 Phase 2 Sevirumab;Foscarnet sodium;Ganciclovir
50 A Phase II/III Study of Encapsulated Human NTC-201 Cell Implants Releasing Ciliary Neurotrophic Factor (CNTF) for Participants With Retinitis Pigmentosa Using Visual Acuity as the Primary Outcome Completed NCT00447993 Phase 2 NT-501;NT-501

Search NIH Clinical Center for Retinitis

Genetic Tests for Retinitis

Anatomical Context for Retinitis

MalaCards organs/tissues related to Retinitis:

40
Retina, Eye, Bone, Testes, T Cells, Brain, Kidney

Publications for Retinitis

Articles related to Retinitis:

(show top 50) (show all 11779)
# Title Authors PMID Year
1
Effects of prolonged dark adaptation in patients with retinitis pigmentosa of Bothnia type: an electrophysiological study. 54 61
17922155 2008
2
The retinal ciliopathies. 54 61
17896309 2007
3
Homozygous deletion related to Alu repeats in RLBP1 causes retinitis punctata albescens. 54 61
17065479 2006
4
Common and divergent roles for members of the mouse DCX superfamily. 54 61
16628014 2006
5
Towards mutation-independent silencing of genes involved in retinal degeneration by RNA interference. 54 61
15877050 2005
6
Novel mutation in RLBP1 gene in a Japanese patient with retinitis punctata albescens. 54 61
15953459 2005
7
A novel compound heterozygous mutation in the cellular retinaldehyde-binding protein gene (RLBP1) in a patient with retinitis punctata albescens. 54 61
15234312 2004
8
Novel mutations in the cellular retinaldehyde-binding protein gene (RLBP1) associated with retinitis punctata albescens: evidence of interfamilial genetic heterogeneity and fundus changes in heterozygotes. 54 61
14718298 2004
9
Antisense oligonucleotides for cancer therapy-an overview. 54 61
12867066 2003
10
Identification and characterisation of the retinitis pigmentosa 1-like1 gene (RP1L1): a novel candidate for retinal degenerations. 54 61
12634863 2003
11
Retinitis pigmentosa-associated rhodopsin mutations in three membrane-located cysteine residues present three different biochemical phenotypes. 54 61
12359230 2002
12
Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene. 54 61
11960024 2002
13
Clinical features and mutations in patients with dominant retinitis pigmentosa-1 (RP1). 54 61
11527933 2001
14
Antisense therapy in oncology: new hope for an old idea? 54 61
11513935 2001
15
Fundus albipunctatus and retinitis punctata albescens in a pedigree with an R150Q mutation in RLBP1. 54 61
11453974 2001
16
Evaluation of RLBP1 in 50 autosomal recessive retinitis pigmentosa and 4 retinitis punctata albescens Spanish families. 54 61
11262646 2001
17
Full-length human L1 insertions retain the capacity for high frequency retrotransposition in cultured cells. 54 61
10401005 1999
18
Mutations in the gene encoding 11-cis retinol dehydrogenase cause delayed dark adaptation and fundus albipunctatus. 54 61
10369264 1999
19
Recessive mutations in the RLBP1 gene encoding cellular retinaldehyde-binding protein in a form of retinitis punctata albescens. 54 61
10102299 1999
20
Retinitis punctata albescens associated with the Arg135Trp mutation in the rhodopsin gene. 54 61
8554077 1996
21
Beneficial effects of saffron (Crocus sativus L.) in ocular pathologies, particularly neurodegenerative retinal diseases. 61
31997799 2020
22
Genome Editing in Patient iPSCs Corrects the Most Prevalent USH2A Mutations and Reveals Intriguing Mutant mRNA Expression Profiles. 61
31909088 2020
23
Multiple cytokine analyses of aqueous humor from the patients with retinitis pigmentosa. 61
31810025 2020
24
Bilateral retinitis after influenza virus infection in a case report. 61
31956727 2020
25
Cytomegalovirus disease in a retinoblastoma cohort: The role of preemptive screening. 61
31793213 2020
26
Parthanatos-associated proteins are stimulated intraocularly during development of experimental murine cytomegalovirus retinitis in mice with retrovirus-induced immunosuppression. 61
31670405 2020
27
(Z)-7,4'-Dimethoxy-6-hydroxy-aurone-4-O-β-glucopyranoside mitigates retinal degeneration in Rd10 mouse model through inhibiting oxidative stress and inflammatory responses. 61
31648555 2020
28
Phenotypic expansion of autosomal dominant retinitis pigmentosa associated with the D477G mutation in RPE65. 61
32014860 2020
29
RNA Splicing Factor Mutations That Cause Retinitis Pigmentosa Result in Circadian Dysregulation. 61
31726916 2020
30
New Nrf2-Inducer Compound ITH12674 Slows the Progression of Retinitis Pigmentosa in the Mouse Model rd10. 61
32028545 2020
31
Expanding the retinal phenotype of RP1: from retinitis pigmentosa to a novel and singular macular dystrophy. 61
31079053 2020
32
Retinitis Pigmentosa Associated with Bardet-Biedl Syndrome with BBS9 Gene Mutation in a Korean Patient. 61
32037757 2020
33
Thiol/disulfide homeostasis in retinitis pigmentosa patients. 61
32024375 2020
34
Novel REEP6 gene mutation associated with autosomal recessive retinitis pigmentosa. 61
31538292 2020
35
Retinitis pigmentosa prior to familial ALS caused by a homozygous cilia and flagella-associated protein 410 mutation. 61
31431468 2020
36
Rhodopsin Genomic Loci DNA Nanoparticles Improve Expression and Rescue of Retinal Degeneration in a Model for Retinitis Pigmentosa. 61
31879189 2020
37
Permanent visual work disabilities: 321 cases review. 61
32035740 2020
38
Retinal vascular inflammatory and occlusive changes in infectious and non-infectious uveitis. 61
32016664 2020
39
[Retinitis pigmentosa]. 61
32030928 2020
40
Sector retinitis pigmentosa. 61
31948687 2020
41
ER complex proteins are required for rhodopsin biosynthesis and photoreceptor survival in Drosophila and mice. 61
31263175 2020
42
The functional impact of the C/N-terminal extensions of the mouse retinal IMPDH1 isoforms: a kinetic evaluation. 61
31838626 2020
43
Clinical-grade production and safe delivery of human ESC derived RPE sheets in primates and rodents. 61
31732225 2020
44
Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration. 61
32028070 2020
45
Expanding the phenotypic spectrum in RDH12-associated retinal disease. 61
32014858 2020
46
Successful treatment of an AIDS patient with prolonged Mycobacterium avium bacteremia, high HIV RNA, HBV infection, Kaposi's sarcoma and cytomegalovirus retinitis. 61
31543435 2020
47
Clinical Features of Ocular Syphilis: a Retrospective Clinical Study in an Italian Referral Centre. 61
32036734 2020
48
Posterior column ataxia with retinitis pigmentosa (PCARP) in an Iranian patient associated with the FLVCR1 gene. 61
32039643 2020
49
Barriers in utilisation of low vision assistive products. 61
31388131 2020
50
Collapsin Response-Mediator Protein 5-Associated Retinitis, Vitritis, and Optic Disc Edema. 61
31676123 2020

Variations for Retinitis

Expression for Retinitis

Search GEO for disease gene expression data for Retinitis.

Pathways for Retinitis

GO Terms for Retinitis

Cellular components related to Retinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell projection GO:0042995 9.91 RPGRIP1 RPGR RP2 RP1 RHO FAM161A
2 cilium GO:0005929 9.73 RPGRIP1 RPGR RP2 RP1 FAM161A EYS
3 ciliary basal body GO:0036064 9.62 TOPORS RPGR RP2 FAM161A
4 photoreceptor inner segment GO:0001917 9.46 RP1 RHO FAM161A CERKL
5 photoreceptor disc membrane GO:0097381 9.4 RHO PDE6A
6 photoreceptor connecting cilium GO:0032391 9.26 TOPORS RPGRIP1 RP1 FAM161A
7 photoreceptor outer segment GO:0001750 9.1 RPGR RP1 RHO PRPH2 EYS CERKL

Biological processes related to Retinitis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 response to stimulus GO:0050896 9.81 RPGRIP1 RPGR RPE65 RP1 RLBP1 RHO
2 detection of light stimulus involved in visual perception GO:0050908 9.52 RPE65 EYS
3 cellular response to light stimulus GO:0071482 9.51 RP1 RHO
4 retinoid metabolic process GO:0001523 9.5 RPE65 RLBP1 RHO
5 retinal cone cell development GO:0046549 9.49 TOPORS RP1
6 rhodopsin mediated signaling pathway GO:0016056 9.48 RHO PDE6A
7 retina morphogenesis in camera-type eye GO:0060042 9.46 RPE65 RP1
8 retinal rod cell development GO:0046548 9.43 TOPORS RP1
9 retina development in camera-type eye GO:0060041 9.43 RPGRIP1 RPE65 RP1 RHO PRPH2 PDE6A
10 photoreceptor cell outer segment organization GO:0035845 9.4 TOPORS RP1
11 phototransduction, visible light GO:0007603 9.37 RP1 RHO
12 visual perception GO:0007601 9.36 RPGRIP1 RPGR RPE65 RP2 RP1 RLBP1
13 vitamin A metabolic process GO:0006776 9.26 RPE65 RLBP1

Molecular functions related to Retinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 11-cis retinal binding GO:0005502 8.62 RLBP1 RHO

Sources for Retinitis

3 CDC
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10 dbSNP
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17 EFO
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33 ICD10 via Orphanet
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57 OMIM via Orphanet
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63 QIAGEN
68 SNOMED-CT via HPO
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70 Tocris
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72 UMLS via Orphanet
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