Aliases & Classifications for Retinitis

MalaCards integrated aliases for Retinitis:

Name: Retinitis 12 56 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3612
MeSH 45 D012173
NCIt 51 C115993
SNOMED-CT 69 35426003
ICD10 34 H30.9
UMLS 74 C0035333

Summaries for Retinitis

MalaCards based summary : Retinitis is related to retinitis pigmentosa 2 and retinitis pigmentosa 28. An important gene associated with Retinitis is RPGR (Retinitis Pigmentosa GTPase Regulator). The drugs Cidofovir and Ganciclovir have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and bone, and related phenotypes are nervous system and vision/eye

Related Diseases for Retinitis

Diseases related to Retinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1960)
# Related Disease Score Top Affiliating Genes
1 retinitis pigmentosa 2 34.1 RP2 RPGR
2 retinitis pigmentosa 28 33.9 FAM161A FLVCR1
3 retinitis pigmentosa 25 33.9 EYS RP9
4 retinitis pigmentosa 7 33.8 PRPH2 RHO RP9
5 retinitis pigmentosa 6 33.8 RHO RP9
6 retinitis pigmentosa 10 33.7 IMPDH1 RHO RP9
7 retinitis pigmentosa 9 33.7 IMPDH1 RP9
8 retinitis pigmentosa 1 33.6 PRPH2 RHO RP1 RP1L1
9 peripheral retinal degeneration 33.5 PRPH2 RPGR
10 fundus albipunctatus 33.4 PRPH2 RHO RLBP1
11 retinal degeneration 33.4 PRPH2 RHO RLBP1 RP2 RPGR RPGRIP1
12 retinitis pigmentosa 18 33.2 IMPDH1 PRPF3 RP9
13 retinitis pigmentosa 13 33.1 IMPDH1 PRPF3 RP9 RPGR
14 cone-rod dystrophy 2 32.9 CERKL FAM161A PRPH2 RHO RPGR RPGRIP1
15 retinal disease 32.7 IMPDH1 PRPF3 PRPH2 RHO RLBP1 RPGR
16 cone dystrophy 32.7 RHO RLBP1 RPGR
17 leber congenital amaurosis 32.5 IMPDH1 PRPH2 RHO RP2 RPGR RPGRIP1
18 bestrophinopathy 32.3 PRPH2 RLBP1
19 stargardt disease 32.2 EYS PRPH2 RHO RPGR
20 usher syndrome, type iid 32.1 RHO RPGR
21 laurence-moon syndrome 31.7 RPGR RPGRIP1
22 fundus dystrophy 30.9 ABHD12 CERKL EYS PRPH2 RHO RLBP1
23 stargardt macular degeneration 29.9 PRPH2 RHO
24 retinitis pigmentosa 28.9 ABHD12 CERKL EYS FAM161A FLVCR1 IMPDH1
25 retinal detachment 12.5
26 retinitis pigmentosa 3 12.5
27 retinal dystrophy with inner retinal dysfunction and ganglion cell abnormalities 12.5
28 retinitis pigmentosa 27 12.4
29 retinitis pigmentosa 12 12.4
30 doyne honeycomb retinal dystrophy 12.4
31 retinitis pigmentosa 50 12.4
32 retinitis pigmentosa 4 12.4
33 retinitis pigmentosa 41 12.4
34 retinitis pigmentosa 11 12.4
35 retinitis pigmentosa 67 12.4
36 central retinal vein occlusion 12.4
37 retinitis pigmentosa 38 12.4
38 retinitis pigmentosa 14 12.4
39 retinitis pigmentosa 46 12.4
40 retinitis pigmentosa 17 12.4
41 retinitis pigmentosa 30 12.4
42 retinitis pigmentosa 19 12.4
43 retinitis pigmentosa 33 12.4
44 retinitis pigmentosa 20 12.4
45 retinitis pigmentosa 40 12.4
46 retinitis pigmentosa 31 12.4
47 retinitis pigmentosa 36 12.4
48 retinitis pigmentosa 26 12.4
49 retinitis pigmentosa 35 12.4
50 retinitis pigmentosa 57 12.4

Graphical network of the top 20 diseases related to Retinitis:



Diseases related to Retinitis

Symptoms & Phenotypes for Retinitis

MGI Mouse Phenotypes related to Retinitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.9 ABHD12 FAM161A PRPH2 RHO RLBP1 RP1
2 vision/eye MP:0005391 9.47 ABHD12 CERKL FAM161A IMPDH1 PRPF3 PRPH2
3 pigmentation MP:0001186 9.43 PRPF3 PRPH2 RHO RLBP1 RPGR SEMA4A

Drugs & Therapeutics for Retinitis

Drugs for Retinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 240)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cidofovir Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 113852-37-2 60613
2
Ganciclovir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 82410-32-0 3454
3
Foscarnet Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 4428-95-9, 63585-09-1 3415
4
Probenecid Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 57-66-9 4911
5
Phosphonoacetic Acid Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 4408-78-0 546
6 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
7 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
8 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
9 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
10 Ganciclovir triphosphate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
11 Anti-Retroviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
12 Reverse Transcriptase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
13 Renal Agents Phase 4,Phase 2,Phase 1,Not Applicable
14
Valganciclovir Approved, Investigational Phase 3,Phase 2,Not Applicable 175865-60-8 64147
15
Eplerenone Approved Phase 2, Phase 3 107724-20-9 443872 150310
16
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
17
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
18
leucovorin Approved Phase 3,Phase 1,Phase 2 58-05-9 143 6006
19
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 2 1177-87-3
20
Pyrimethamine Approved, Investigational, Vet_approved Phase 3 58-14-0 4993
21
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
22
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
23
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
24
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2 50-02-2 5743
25
Sulfadiazine Approved, Investigational, Vet_approved Phase 3 68-35-9 5215
26
Sargramostim Approved, Investigational Phase 3,Not Applicable 123774-72-1, 83869-56-1
27
Tocopherol Approved, Investigational Phase 3 1406-66-2 14986
28
Acyclovir Approved Phase 3,Not Applicable 59277-89-3 2022
29
Celecoxib Approved, Investigational Phase 3 169590-42-5 2662
30
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 1,Phase 2,Early Phase 1 59-30-3 6037
31
Vitamin D Approved, Nutraceutical, Vet_approved Phase 3 1406-16-2
32
Lutein Approved, Investigational, Nutraceutical Phase 3,Phase 1,Phase 2 127-40-2 6433159
33
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3,Phase 1 68-26-8, 22737-96-8, 11103-57-4 9904001 445354
34
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
35
Beta carotene Approved, Nutraceutical Phase 2, Phase 3,Phase 1 7235-40-7
36
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7
37 Tocotrienol Investigational Phase 3 6829-55-6
38 Hormone Antagonists Phase 2, Phase 3,Phase 3,Phase 1
39 Diuretics, Potassium Sparing Phase 2, Phase 3,Phase 1
40 Natriuretic Agents Phase 2, Phase 3,Phase 1
41 Antihypertensive Agents Phase 2, Phase 3,Phase 3,Phase 1
42 diuretics Phase 2, Phase 3,Phase 1
43 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3,Phase 3,Phase 1
44 Hormones Phase 2, Phase 3,Phase 3,Phase 1
45 Mineralocorticoid Receptor Antagonists Phase 2, Phase 3,Phase 1
46 Mineralocorticoids Phase 2, Phase 3,Phase 1
47 Protective Agents Phase 3,Phase 2,Phase 1
48 glucocorticoids Phase 3,Phase 2
49 Clindamycin phosphate Phase 3
50 Neuroprotective Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 264)
# Name Status NCT ID Phase Drugs
1 Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis Completed NCT00000894 Phase 4 Cidofovir;Probenecid;Ganciclovir
2 The Role of Capsular Tension Ring (CTR) in Anterior Capsular Contraction Completed NCT00717080 Phase 4
3 A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium) Completed NCT00002125 Phase 4 Foscarnet sodium
4 Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Completed NCT01866397 Phase 4
5 Use of Cidofovir for Recurrent Respiratory Papillomatosis Completed NCT00205374 Phase 4 Cidofovir;Placebo
6 Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection Unknown status NCT00017784 Phase 3 Valganciclovir
7 A Study of the Beneficial Effects of Eplerenone on Central Serous Chorioretinopathy Unknown status NCT02215330 Phase 2, Phase 3 Eplerenone;Maltodextrin
8 To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis Unknown status NCT00372294 Phase 3 pyrimethamine-sulfadiazine + prednisolone;Clindamycin+Dexamethasone
9 Clinical Trial of Lutein for Patients With Retinitis Pigmentosa Receiving Vitamin A Completed NCT00346333 Phase 3 Lutein
10 Randomized Trial for Retinitis Pigmentosa Completed NCT00000116 Phase 3 Vitamin A;Nutritional Supplement
11 Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) Completed NCT00000142 Phase 2, Phase 3 Cidofovir
12 Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) Completed NCT00000135 Phase 2, Phase 3 MSL-109
13 A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00000688 Phase 3 Ganciclovir
14 Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) Completed NCT00000134 Phase 3 Ganciclovir;Foscarnet
15 A Treatment Protocol for the Use of Intravenous Ganciclovir in AIDS Patients With Immediately Sight-Threatening CMV Retinitis Completed NCT00000698 Phase 3 Ganciclovir
16 Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis Completed NCT00002070 Phase 3 Sargramostim;Ganciclovir
17 Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) Completed NCT00000136 Phase 3 Foscarnet;Ganciclovir
18 Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa Completed NCT00000114 Phase 3 Vitamin E;Vitamin A
19 Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Completed NCT00000143 Phase 3 Cidofovir intravenous
20 Ganciclovir Implant Study for Cytomegalovirus Retinitis Completed NCT00000118 Phase 3
21 A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Completed NCT00002377 Phase 3 Valganciclovir;Ganciclovir
22 Valganciclovir in Prevention of Cytomegalovirus (CMV) Reactivation Following Allogeneic-Stem Cell Transplantation (SCT) Completed NCT00330018 Phase 3 Valganciclovir;Acyclovir
23 Ozurdex for Macular Edema Post Membrane Peeling Completed NCT01273727 Phase 2, Phase 3 Dexamethasone;dexamethasone
24 Laser and Medical Treatment of Diabetic Macular Edema Completed NCT00050479 Phase 3 Celecoxib (Celebrex)
25 Letermovir (MK-8228) Versus Placebo in the Prevention of Clinically-Significant Cytomegalovirus (CMV) Infection in Adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients (MK-8228-001) Completed NCT02137772 Phase 3 Letermovir;Placebo
26 A Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Recruiting NCT03116113 Phase 2, Phase 3
27 The Effect of Oral Administration of 9-cis β Carotene Rich Powder of the Alga Dunaliella Bardawil Recruiting NCT01680510 Phase 2, Phase 3
28 Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Patients With Moderate to Severe Obesity Recruiting NCT03746522 Phase 3 Setmelanotide;Placebos
29 Setmelanotide Phase 2 Treatment Trial in Patients With Rare Genetic Disorders of Obesity Recruiting NCT03013543 Phase 2, Phase 3 Setmelanotide
30 Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis Active, not recruiting NCT00999609 Phase 3
31 Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome Active, not recruiting NCT03184584 Phase 2, Phase 3 PBI-4050
32 Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis: Treatment Outcomes Not yet recruiting NCT03586284 Phase 2, Phase 3 Valganciclovir Hydrochloride;Ganciclovir Sodium;Placebo Oral Tablet;Topical placebo
33 Phase III Efficacy and Safety Clinical Study of UF-021 for Treatment of Retinitis Pigmentosa Terminated NCT01786395 Phase 3 UF-021;Placebo
34 Aflibercept for Macular Oedema With Underlying Retinitis Pigmentosa (AMOUR) Study Unknown status NCT02661711 Phase 2 Aflibercept
35 Clinical Study to Evaluate Safety and Efficacy of BMMNC in Retinitis Pigmentosa Unknown status NCT01914913 Phase 1, Phase 2
36 Intravitreal Dexamethasone Implant in Retinitis Pigmentosa-related Macular Edema- a Retrospective Study Unknown status NCT02804360 Phase 2
37 Autologous Bone Marrow-Derived Stem Cells Transplantation For Retinitis Pigmentosa Completed NCT01560715 Phase 2
38 Trial of Oral Valproic Acid for Retinitis Pigmentosa Completed NCT01233609 Phase 2 Valproic Acid;Placebo
39 Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis Pigmentosa Completed NCT02140164 Phase 1, Phase 2 Minocycline
40 A Study of Encapsulated Cell Technology (ECT) Implant for Patients With Late Stage Retinitis Pigmentosa Completed NCT00447993 Phase 2 NT-501;NT-501
41 Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis Pigmentosa Completed NCT02320812 Phase 1, Phase 2
42 Safety Study in Retinal Transplantation for Retinitis Pigmentosa. Completed NCT00345917 Phase 2
43 A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa Completed NCT00447980 Phase 2 NT-501;NT-501
44 CMV Retinitis Retreatment Trial Completed NCT00000766 Phase 2 Foscarnet sodium;Ganciclovir
45 Effects of Lutein in Retinitis Pigmentosa Completed NCT00029289 Phase 1, Phase 2 Lutein (10 or 30 mg/day) capsules
46 Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema Completed NCT02609165 Phase 2 rhNGF 180 µg/ml eye drops solution;vehicle eye drops
47 A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR ) Completed NCT00002156 Phase 2 Fomivirsen sodium;Ganciclovir
48 A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis Completed NCT00002169 Phase 2 Nelfinavir mesylate
49 DHA and X-Linked Retinitis Pigmentosa Completed NCT00100230 Phase 2 docosahexaenoic acid OR corn/soy oil placebo
50 A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure Completed NCT00000691 Phase 2 Foscarnet sodium

Search NIH Clinical Center for Retinitis

Genetic Tests for Retinitis

Anatomical Context for Retinitis

MalaCards organs/tissues related to Retinitis:

42
Eye, Retina, Bone, T Cells, Testes, Brain, Bone Marrow

Publications for Retinitis

Articles related to Retinitis:

(show top 50) (show all 4569)
# Title Authors Year
1
Cytomegalovirus retinitis, in a diabetic immunocompetent patient, after intravitreal ranibizumab injection. ( 29747535 )
2019
2
Aqueous cytomegalovirus DNA and interleukin-8 determination in management of cytomegalovirus retinitis. ( 30187638 )
2019
3
Active cytomegalovirus retinitis after the start of antiretroviral therapy. ( 30196272 )
2019
4
Use of Letermovir as Salvage Therapy for Drug-Resistant Cytomegalovirus Retinitis. ( 30642941 )
2019
5
Cytomegalovirus Retinitis during Maintenance Therapy in child with Acute Lymphoblastic Leukemia. ( 31086168 )
2019
6
Abnormal levels of aqueous humor trace elements in patients with cytomegalovirus retinitis. ( 31065104 )
2019
7
Relationship Between Opacity of Cytomegalovirus Retinitis Lesion Borders and Severity of Immunodeficiency Among People With AIDS. ( 31042791 )
2019
8
A Lymphoma Patient with Cytomegalovirus Retinitis and Post-Autologous Hematopoietic Cell Transplantation Immune Reconstitution Uveitis: A Case Report and Review of the Literature. ( 31033155 )
2019
9
SOCS and Herpesviruses, With Emphasis on Cytomegalovirus Retinitis. ( 31031749 )
2019
10
Polymerase chain reaction analysis of aqueous humor specimens in the diagnosis of cytomegalovirus retinitis in AIDS patients. ( 30968705 )
2019
11
Cytomegalovirus Retinitis Associated with Lenalidomide Use for Multiple Myeloma in an Immunocompetent Patient. ( 30937202 )
2019
12
Concurrent cerebral toxoplasmosis and cytomegalovirus retinitis in a patient with human immunodeficiency virus. ( 30851795 )
2019
13
A cross-sectional study of cytomegalovirus retinitis in HIV-1 infected adults in Nigeria. ( 30837414 )
2019
14
Macular oedema due to immune reconstitution uveitis occurring in an HIV-negative patient without cytomegalovirus retinitis. ( 30009623 )
2019
15
CD4+ cells as a potential biomarker for cytomegalovirus retinitis in children with acute lymphocytic leukemia. ( 30681505 )
2019
16
Intraocular cytokine profile and autoimmune reactions in retinitis pigmentosa, age-related macular degeneration, glaucoma and cataract. ( 30298670 )
2019
17
Drosophila melanogaster: A Valuable Genetic Model Organism to Elucidate the Biology of Retinitis Pigmentosa. ( 30324448 )
2019
18
Cytomegalovirus Retinitis in Children and Adolescents with Acute Leukemia following allogeneic Hematopoietic Stem Cell Transplantation. ( 30972869 )
2019
19
Generation of gene-corrected human induced pluripotent stem cell lines derived from retinitis pigmentosa patient with Ser331Cysfs*5 mutation in MERTK. ( 30612079 )
2019
20
Establishment and characterization of an iPSC line (FRIMOi001-A) derived from a retinitis pigmentosa patient carrying PDE6A mutations. ( 30685614 )
2019
21
Classification of disease severity in retinitis pigmentosa. ( 30705041 )
2019
22
Optical Coherence Tomography Angiography of RPGR-Associated Retinitis Pigmentosa Suggests Foveal Avascular Zone is a Biomarker for Vision Loss. ( 30768229 )
2019
23
Correction: Novel PDE6B Mutation Presenting with Retinitis Pigmentosa - A Case Series of Three Patients. ( 30769346 )
2019
24
Correlation between Visual Function and Structural Characteristics of the Macula in Advanced Retinitis Pigmentosa. ( 30893682 )
2019
25
Early detection of cone photoreceptor cell loss in retinitis pigmentosa using adaptive optics scanning laser ophthalmoscopy. ( 30937533 )
2019
26
Asymmetric bilateral retinitis in patient with subacute sclerosing panencephalitis. ( 31001903 )
2019
27
Correlation between aqueous flare and residual visual field area in retinitis pigmentosa. ( 29858180 )
2019
28
Functional characterization of CEP250 variant identified in nonsyndromic retinitis pigmentosa. ( 30998843 )
2019
29
Phenotypic spectrum of autosomal recessive retinitis pigmentosa without posterior column ataxia caused by mutations in the FLVCR1 gene. ( 30656474 )
2019
30
Correlation between B-scan optical coherence tomography, en face thickness map ring and hyperautofluorescent ring in retinitis pigmentosa patients. ( 31049658 )
2019
31
Genetic and clinical findings in a large cohort of Chinese patients with suspected retinitis pigmentosa. ( 31054281 )
2019
32
Generation of an induced pluripotent stem cell line from a patient with retinitis pigmentosa caused by RP1 mutation. ( 31059986 )
2019
33
Disrupted plasma membrane protein homeostasis in a Xenopus laevis model of retinitis pigmentosa. ( 31061086 )
2019
34
A novel RP2 missense mutation Q158P identified in an X-linked retinitis pigmentosa family impaired RP2 protein stability. ( 31071385 )
2019
35
Novel non-sense mutation in RP2 (c.843_844insT/p.Arg282fs) is associated with a severe phenotype of retinitis pigmentosa without evidence of primary retinal pigment epithelium involvement. ( 31079036 )
2019
36
Expanding the retinal phenotype of RP1: from retinitis pigmentosa to a novel and singular macular dystrophy. ( 31079053 )
2019
37
Generation of an iPSC line from a retinitis pigmentosa patient carrying a homozygous mutation in CERKL and a healthy sibling. ( 31082679 )
2019
38
Antisense Oligonucleotide-Based Downregulation of the G56R Pathogenic Variant Causing NR2E3-Associated Autosomal Dominant Retinitis Pigmentosa. ( 31083481 )
2019
39
Vascular dysfunction in retinitis pigmentosa. ( 31099494 )
2019
40
Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin. ( 31100078 )
2019
41
Microglia Mediate Synaptic Material Clearance at the Early Stage of Rats With Retinitis Pigmentosa. ( 31105708 )
2019
42
Development of a Molecularly Stable Gene Therapy Vector for the Treatment of RPGR-associated X-linked Retinitis Pigmentosa. ( 31106594 )
2019
43
Altered airway ciliary orientation in patients with X-linked retinitis pigmentosa. ( 31110053 )
2019
44
Metipranolol promotes structure and function of retinal photoreceptors in the rd10 mouse model of human retinitis pigmentosa. ( 30315650 )
2019
45
Sector Retinitis Pigmentosa caused by mutations of the RHO gene. ( 30390055 )
2019
46
Outer retinal layers as predictors of visual acuity in retinitis pigmentosa: a cross-sectional study. ( 30456418 )
2019
47
A novel CRX variant (p.R98X) is identified in a Chinese family of Retinitis pigmentosa with atypical and mild manifestations. ( 30460480 )
2019
48
Spectral domain optical coherence tomography for monitoring candida retinitis. ( 30503346 )
2019
49
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN PATIENTS WITH RETINITIS PIGMENTOSA. ( 30570620 )
2019
50
Simultaneous presentation of ocular surface squamous neoplasia with viral retinitis in HIV-positive patients with low CD4 counts. ( 30574905 )
2019

Variations for Retinitis

Expression for Retinitis

Search GEO for disease gene expression data for Retinitis.

Pathways for Retinitis

GO Terms for Retinitis

Cellular components related to Retinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell projection GO:0042995 9.91 FAM161A RHO RP1 RP1L1 RP2 RPGR
2 cilium GO:0005929 9.73 FAM161A RP1 RP1L1 RP2 RPGR RPGRIP1
3 ciliary basal body GO:0036064 9.62 FAM161A RP2 RPGR TOPORS
4 axoneme GO:0005930 9.58 RP1 RP1L1 RPGRIP1
5 photoreceptor inner segment GO:0001917 9.46 CERKL FAM161A RHO RP1
6 photoreceptor connecting cilium GO:0032391 9.35 FAM161A RP1 RP1L1 RPGRIP1 TOPORS
7 photoreceptor outer segment GO:0001750 9.1 PRPH2 CERKL RHO RP1 RP1L1 RPGR

Biological processes related to Retinitis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 response to stimulus GO:0050896 9.76 EYS FAM161A RHO RLBP1 RP1 RP1L1
2 cell projection organization GO:0030030 9.67 FAM161A RP1 RP1L1 RPGR
3 axoneme assembly GO:0035082 9.51 RP1 RP1L1
4 cellular response to light stimulus GO:0071482 9.49 RHO RP1
5 photoreceptor cell outer segment organization GO:0035845 9.48 RP1 TOPORS
6 retinal cone cell development GO:0046549 9.46 RP1 TOPORS
7 retinal rod cell development GO:0046548 9.43 RP1 TOPORS
8 photoreceptor cell maintenance GO:0045494 9.43 RHO RP1 RP1L1
9 phototransduction, visible light GO:0007603 9.4 RHO RP1
10 retina development in camera-type eye GO:0060041 9.35 PRPH2 RHO RP1 RP1L1 RPGRIP1
11 photoreceptor cell development GO:0042461 9.32 RP1 RP1L1
12 visual perception GO:0007601 9.32 RPGRIP1 RPGR RP2 RP1 PRPH2 EYS

Molecular functions related to Retinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 11-cis retinal binding GO:0005502 8.62 RHO RLBP1

Sources for Retinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....