MCID: RTR004
MIFTS: 36

Retroperitoneum Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Retroperitoneum Carcinoma

MalaCards integrated aliases for Retroperitoneum Carcinoma:

Name: Retroperitoneum Carcinoma 12 15
Retroperitoneal Neoplasms 44 73
Retroperitoneal Cancer 12 15
Malignant Neoplasm of Retroperitoneum and Peritoneum 12
Malignant Tumor of Peritoneum and Retroperitoneum 12
Malignant Neoplasm of Retroperitoneum 12
Carcinoma of the Retroperitoneum 12
Malignant Retroperitoneal Cancer 12
Neoplasm of the Retroperitoneum 12
Carcinoma of Retroperitoneum 12
Neoplasm of Retroperitoneum 12
Retroperitoneal Neoplasm 12
Tumor of Retroperitoneum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12342 DOID:5875
ICD10 33 C48 C48.0
ICD9CM 35 158 158.0
MeSH 44 D012186
SNOMED-CT 68 94092006

Summaries for Retroperitoneum Carcinoma

Disease Ontology : 12 An organ system cancer located in the retroperitoneal space that is manifested in retroperitoneal space in the abdominal cavity behind the peritoneum.

MalaCards based summary : Retroperitoneum Carcinoma, also known as retroperitoneal neoplasms, is related to retroperitoneal sarcoma and malignant peripheral nerve sheath tumor, and has symptoms including sister mary joseph's nodule An important gene associated with Retroperitoneum Carcinoma is MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9), and among its related pathways/superpathways are Transcription Ligand-dependent activation of the ESR1/SP pathway and Regulation of retinoblastoma protein. Affiliated tissues include liver, colon and the retroperitoneal space, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Retroperitoneum Carcinoma

Graphical network of the top 20 diseases related to Retroperitoneum Carcinoma:



Diseases related to Retroperitoneum Carcinoma

Symptoms & Phenotypes for Retroperitoneum Carcinoma

UMLS symptoms related to Retroperitoneum Carcinoma:


sister mary joseph's nodule

GenomeRNAi Phenotypes related to Retroperitoneum Carcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.53 MAP3K9
2 Decreased viability GR00221-A-1 9.53 CDKN2A SMARCB1
3 Decreased viability GR00221-A-2 9.53 MAP3K9 SMARCB1
4 Decreased viability GR00221-A-3 9.53 CDKN2A MAP3K9 SMARCB1
5 Decreased viability GR00221-A-4 9.53 CDKN2A
6 Decreased viability GR00342-S-1 9.53 MAP3K9
7 Decreased viability GR00342-S-2 9.53 MAP3K9
8 Decreased viability GR00342-S-3 9.53 MAP3K9
9 Decreased viability GR00381-A-1 9.53 SMARCB1
10 Decreased viability GR00402-S-2 9.53 CDKN2A MAP3K9 SMARCB1

MGI Mouse Phenotypes related to Retroperitoneum Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.77 CASZ1 CDKN2A CREBBP SMARCB1 SMTN
2 growth/size/body region MP:0005378 9.73 CASZ1 CDKN2A CREBBP SMARCB1 SMTN UPK2
3 digestive/alimentary MP:0005381 9.72 CDKN2A CREBBP MAP3K9 SMARCB1 SMTN
4 mortality/aging MP:0010768 9.5 CASZ1 CDKN2A CREBBP MAP3K9 SMARCB1 SMTN
5 liver/biliary system MP:0005370 9.46 CASZ1 CDKN2A CREBBP SMARCB1
6 muscle MP:0005369 9.1 CASZ1 CDKN2A CREBBP MAP3K9 SMARCB1 SMTN

Drugs & Therapeutics for Retroperitoneum Carcinoma

Search Clinical Trials , NIH Clinical Center for Retroperitoneum Carcinoma

Cochrane evidence based reviews: retroperitoneal neoplasms

Genetic Tests for Retroperitoneum Carcinoma

Anatomical Context for Retroperitoneum Carcinoma

MalaCards organs/tissues related to Retroperitoneum Carcinoma:

41
Liver, Colon

The Foundational Model of Anatomy Ontology organs/tissues related to Retroperitoneum Carcinoma:

19
The Retroperitoneal Space

Publications for Retroperitoneum Carcinoma

Articles related to Retroperitoneum Carcinoma:

# Title Authors Year
1
Small bowel toxicity after high dose spot scanning-based proton beam therapy for paraspinal/retroperitoneal neoplasms. ( 24052010 )
2013
2
Resection of advanced stage malignant retroperitoneal neoplasms with tumor thrombus extending into the right atrium: report of four cases. ( 21264766 )
2011
3
CT characteristics of primary retroperitoneal neoplasms in children. ( 20591598 )
2010
4
Retroperitoneal neoplasms within the perirenal space in infants and children: differentiation of renal and non-renal origin in enhanced CT images. ( 20598465 )
2010
5
CT characteristics of primary retroperitoneal neoplasms. ( 15554383 )
2004
6
Primary retroperitoneal neoplasms: CT and MR imaging findings with anatomic and pathologic diagnostic clues. ( 12533639 )
2003
7
Clinical utility of endoscopic ultrasound and endscopic ultrasound-guided fine needle aspiration in retroperitoneal neoplasms. ( 10811326 )
2000
8
Primary retroperitoneal neoplasms: how close can we come in making the correct diagnosis. ( 1337801 )
1992
9
Primary retroperitoneal neoplasms: CT findings in 90 cases with clinical and pathologic correlation. ( 2535771 )
1989
10
Regional oxygenation in the diagnosis and management of intra-abdominal and retroperitoneal neoplasms. ( 5833630 )
1965

Variations for Retroperitoneum Carcinoma

Expression for Retroperitoneum Carcinoma

Search GEO for disease gene expression data for Retroperitoneum Carcinoma.

Pathways for Retroperitoneum Carcinoma

Pathways related to Retroperitoneum Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11 CREBBP SMARCB1
2 10.7 CREBBP SMARCB1
3 10.36 CDKN2A CREBBP

GO Terms for Retroperitoneum Carcinoma

Biological processes related to Retroperitoneum Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein destabilization GO:0031648 8.62 CDKN2A CREBBP

Molecular functions related to Retroperitoneum Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 p53 binding GO:0002039 8.62 CREBBP SMARCB1

Sources for Retroperitoneum Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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