RCVS
MCID: RVR002
MIFTS: 28

Reversible Cerebral Vasoconstriction Syndrome (RCVS)

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Reversible Cerebral Vasoconstriction Syndrome

MalaCards integrated aliases for Reversible Cerebral Vasoconstriction Syndrome:

Name: Reversible Cerebral Vasoconstriction Syndrome 52 58 71
Rcvs 52 58

Characteristics:

Orphanet epidemiological data:

58
reversible cerebral vasoconstriction syndrome
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

ICD10 via Orphanet 33 I67.8
UMLS via Orphanet 72 C3544214
Orphanet 58 ORPHA284388
UMLS 71 C3544214

Summaries for Reversible Cerebral Vasoconstriction Syndrome

NIH Rare Diseases : 52 The following summary is from Orphanet , a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 284388 Definition Reversible cerebral vasoconstriction syndrome (RCVS) is an infrequent cerebrovascular disorder characterized by severe headaches with or without focal neurological deficits or seizures , and a reversible segmental and multifocal vasoconstriction of cerebral arteries. Epidemiology RCVS occurs predominantly in females before the age of 50. Clinical description The most common clinical feature of RCVS is severe acute headache. The major complication of RCVS is ischemic or hemorrhagic stroke. Etiology The exact pathophysiology of RCVS remains unknown and the prevailing hypothesis involves a transient disturbance in the control of cerebral vascular tone. RCVS may occur spontaneously or be provoked by various precipitating factors, the most common being postpartum and exposure to various vasoactive substances such as illicit drugs and selective serotonin-reuptake inhibitors. Visit the Orphanet disease page for more resources.

MalaCards based summary : Reversible Cerebral Vasoconstriction Syndrome, also known as rcvs, is related to headache and thunderclap headache. The drugs Immunologic Factors and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and heart.

Wikipedia : 74 Reversible cerebral vasoconstriction syndrome (RCVS, sometimes called Call-Fleming syndrome) is a... more...

Related Diseases for Reversible Cerebral Vasoconstriction Syndrome

Diseases related to Reversible Cerebral Vasoconstriction Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 headache 11.0
2 thunderclap headache 11.0
3 vasculitis 10.7
4 encephalopathy 10.7
5 migraine with or without aura 1 10.6
6 primary angiitis of the central nervous system 10.6
7 central nervous system vasculitis 10.5
8 brain edema 10.4
9 systemic lupus erythematosus 10.4
10 lupus erythematosus 10.4
11 pre-eclampsia 10.3
12 eclampsia 10.3
13 thrombophilia due to thrombin defect 10.3
14 aphasia 10.3
15 hemiplegia 10.3
16 visual epilepsy 10.3
17 intracranial hypertension 10.3
18 seizure disorder 10.3
19 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.2
20 ocular motor apraxia 10.2
21 yemenite deaf-blind hypopigmentation syndrome 10.2
22 paraganglioma 10.2
23 cerebrovascular disease 10.2
24 carotid artery dissection 10.2
25 mast cell activation syndrome 10.2
26 polysubstance abuse 10.1
27 aplastic anemia 10.1
28 leukemia, acute lymphoblastic 10.1
29 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 10.1
30 lymphocytic leukemia 10.1
31 thrombotic thrombocytopenic purpura 10.1
32 amnestic disorder 10.1
33 pituitary apoplexy 10.1
34 cortical blindness 10.1
35 carotid stenosis 10.1
36 transient global amnesia 10.1
37 myoma 10.1
38 antiphospholipid syndrome 10.1
39 purpura 10.1
40 intracranial hypotension 10.1
41 hypertensive encephalopathy 10.1
42 spinal cord injury 10.1
43 porphyria, acute intermittent 10.1
44 porphyria 10.1
45 disease of mental health 10.1
46 new daily-persistent headache 10.1
47 clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly 10.0
48 multiple sclerosis 10.0
49 fibromuscular dysplasia 10.0
50 schimke immunoosseous dysplasia 10.0

Graphical network of the top 20 diseases related to Reversible Cerebral Vasoconstriction Syndrome:



Diseases related to Reversible Cerebral Vasoconstriction Syndrome

Symptoms & Phenotypes for Reversible Cerebral Vasoconstriction Syndrome

Drugs & Therapeutics for Reversible Cerebral Vasoconstriction Syndrome

Drugs for Reversible Cerebral Vasoconstriction Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunologic Factors
2 Antibodies
3 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 RCVS: The Rational Approach to Diagnosis and Treatment Withdrawn NCT03150524 Phase 4 Nimodipine;Verapamil ER
2 Perfusion MRI in Reversible Cerebral Vasoconstriction Syndrome Unknown status NCT02756416
3 Reversible Cerebral Vasoconstriction Syndrome With Concomitant Transient Global Amnesia : a Serie of 3 Cases Report Completed NCT03739008
4 Non Invasive Assessment of Morphological and Functional Retinal Patterns in Reversible Cerebral Vasoconstriction Syndrome Using Transorbital Echotomography Doppler, Retinography and Retinal Vessel Analyser Completed NCT03204110
5 Circadian Variation of Cardiac Troponin Completed NCT02091427
6 Identification of Reversible Cerebral Vasoconstriction Syndrome's Precipitating Factors. Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome Recruiting NCT04179383
7 Association Between Reversible Cerebral Vasoconstriction Syndrome and Herpes Zoster Infection Recruiting NCT03509701
8 Intracranial Artery Stenosis Magnetic Resonance Imaging: Aetiology and Progression (ICASMAP) Recruiting NCT03417063

Search NIH Clinical Center for Reversible Cerebral Vasoconstriction Syndrome

Genetic Tests for Reversible Cerebral Vasoconstriction Syndrome

Anatomical Context for Reversible Cerebral Vasoconstriction Syndrome

MalaCards organs/tissues related to Reversible Cerebral Vasoconstriction Syndrome:

40
Brain, Testes, Heart, Bone, Kidney, T Cells, Endothelial

Publications for Reversible Cerebral Vasoconstriction Syndrome

Articles related to Reversible Cerebral Vasoconstriction Syndrome:

(show top 50) (show all 946)
# Title Authors PMID Year
1
Clinical Application of Overlapping Confidence Intervals for Monitoring Changes in Serial Clinical Chemistry Test Results. 61
31858759 2020
2
RCVS urged to adopt 'complete openness'. 61
32029651 2020
3
Standard of proof at RCVS disciplinary hearings. 61
32029670 2020
4
Niall Connell, president of the RCVS, responds. 61
32029672 2020
5
Is the RCVS council transparent enough? 61
32001575 2020
6
RCVS at early stage of disciplinary changes. 61
32001587 2020
7
A Systematic Approach to Improve Scatter Sensitivity of a Flow Cytometer for Detection of Extracellular Vesicles. 61
32017331 2020
8
Long-Term Outcomes After Reversible Cerebral Vasoconstriction Syndrome. 61
31842705 2020
9
Concomitant reversible cerebral vasoconstriction syndrome and transient global amnesia. 61
31650256 2020
10
[Reversible cerebral vasoconstriction syndrome - a common cause of thunderclap headache]. 61
32009625 2020
11
Urine metabolomics signatures in reversible cerebral vasoconstriction syndrome. 61
31910660 2020
12
Reversible cerebral vasoconstriction syndrome: perhaps not so reversible? 61
32001224 2020
13
Grief-induced reversible cerebral vasoconstriction syndrome (RCVS). 61
31996381 2020
14
Why join the RCVS Fellowship? 61
31953300 2020
15
Experiences of recent graduates: reframing reflection as purposeful, social activity. 61
31826933 2019
16
Evaluation on the risk controlling value of urban soil organic pollutants based on land-use planning in China. 61
31076981 2019
17
The Spectrum of Nontraumatic Convexity Subarachnoid Hemorrhage. 61
31677961 2019
18
Neurovascular disorders in pregnancy: A review. 61
31853255 2019
19
Status epilepticus in pregnancy - Can we frame a uniform treatment protocol? 61
31303443 2019
20
Intra-Arterial Verapamil Treatment in Oral Therapy-Refractory Reversible Cerebral Vasoconstriction Syndrome. 61
31879333 2019
21
Reply to "Reversible Cerebral Vasoconstriction Syndrome Responsive to Intravenous Milrinone". 61
31863420 2019
22
Reply to "Reversible Cerebral Vasoconstriction Syndrome Responsive to Intravenous Milrinone". 61
31863421 2019
23
Reversible cerebral vasoconstriction syndrome after sudden caffeine withdrawal. 61
31822176 2019
24
Reversible cerebral vasoconstriction syndrome during caesarean section. 61
31811105 2019
25
Cesarean section under general anesthesia for antepartum reversible cerebral vasoconstriction syndrome: A case report. 61
31463978 2019
26
Fatal reversible cerebral vasoconstriction syndrome: A systematic review of case series and case reports. 61
31416730 2019
27
Leuprolide acetate pseudomenopause therapy as a cause of reversible cerebral vasoconstriction syndrome. 61
31671338 2019
28
Reversible cerebral vasoconstriction with thunderclap headache: A case report. 61
31804357 2019
29
Analysis of postpartum reversible cerebral vasoconstriction syndrome in China: A case report and literature review. 61
31702607 2019
30
Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome: Distinct Clinical Entities with Overlapping Pathophysiology. 61
31582040 2019
31
Reversible Cerebral Vasoconstriction Syndrome and Sickle Cell Disease: A Case Report. 61
31789782 2019
32
Fulminant Reversible Cerebral Vasoconstriction Syndrome After Carotid Endarterectomy for Asymptomatic Stenosis. 61
31733386 2019
33
Vessel Wall Imaging of Cerebrovascular Disorders. 61
31728661 2019
34
Urgent guidance on exports agreed by RCVS. 61
31676609 2019
35
RCVS and TGA: a common pathophysiology? 61
31385018 2019
36
Fast 0/1-h algorithm for detection of NSTEMI: are current high-sensitivity cardiac troponin assays fit for purpose? An EQA-based evaluation. 61
31326959 2019
37
Spreading word of the Practice Standards Scheme. 61
31780501 2019
38
Lara Carim, head of digital and communications at RCVS Knowledge, responds. 61
31604875 2019
39
RCVS makes amendments to its new CPD policy. 61
31628222 2019
40
Melissa Donald, chair of the RCVS standards committee, responds. 61
31582492 2019
41
RCVS signs recognition agreement with Ireland. 61
31604851 2019
42
Surrey vet school gains RCVS accreditation. 61
31604852 2019
43
RCVS accreditation for grenada's vet school. 61
31604887 2019
44
Malignant PRES and RCVS after brain surgery in the early postpartum period. 61
31470358 2019
45
Acute Headache in the Emergency Setting. 61
31589569 2019
46
Is the Presence of Headache Indispensable in Diagnosing Reversible Cerebral Vasoconstriction Syndrome? 61
31591855 2019
47
Caution over RCVS review. 61
31582491 2019
48
Reversible cerebral vasoconstriction syndrome associated with a traditional Japanese training method under a waterfall named Takigyo: a case report. 61
31592108 2019
49
[Reversible Cerebral Vasoconstriction Syndrome with Cortical Subarachnoid Hemorrhage due to Acute Cortical Infarction Beneath the Sulcus:A Case Report]. 61
31666424 2019
50
Reversible cerebral vasoconstrictive syndrome preceded by minor head trauma. 61
31650858 2019

Variations for Reversible Cerebral Vasoconstriction Syndrome

Expression for Reversible Cerebral Vasoconstriction Syndrome

Search GEO for disease gene expression data for Reversible Cerebral Vasoconstriction Syndrome.

Pathways for Reversible Cerebral Vasoconstriction Syndrome

GO Terms for Reversible Cerebral Vasoconstriction Syndrome

Sources for Reversible Cerebral Vasoconstriction Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....