MCID: RHB002
MIFTS: 42

Rhabdoid Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Rhabdoid Meningioma

MalaCards integrated aliases for Rhabdoid Meningioma:

Name: Rhabdoid Meningioma 12 15 73
Papillary Meningioma 12 55 73
Meningioma, Rhabdoid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5058
NCIt 50 C6909

Summaries for Rhabdoid Meningioma

MalaCards based summary : Rhabdoid Meningioma, also known as papillary meningioma, is related to ganglioglioma and chordoma. An important gene associated with Rhabdoid Meningioma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Glioblastoma Multiforme and Cytoskeletal Signaling. The drugs Fentanyl and Donepezil have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and bone, and related phenotypes are Decreased cell migration and Increased proliferation

Related Diseases for Rhabdoid Meningioma

Diseases related to Rhabdoid Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Related Disease Score Top Affiliating Genes
1 ganglioglioma 29.8 BRAF GFAP SMARCB1
2 chordoma 29.7 GFAP SMARCB1 VIM
3 meningioma, familial 29.7 GFAP NF2 SMARCB1
4 papillary meningioma of the cerebellum 12.2
5 adult papillary meningioma 12.2
6 papillary tumor of the pineal region 10.1 BRAF VIM
7 adenofibroma 10.1 BRAF VIM
8 primitive neuroectodermal tumor of the cervix uteri 10.1 GFAP VIM
9 cutaneous leiomyosarcoma 10.1 GFAP VIM
10 pilocytic astrocytoma 10.1 BRAF GFAP
11 cerebral convexity meningioma 10.1 GFAP NF2
12 intraventricular meningioma 10.1 GFAP NF2
13 parachordoma 10.1 GFAP VIM
14 chordoid meningioma 10.1 GFAP VIM
15 clear cell ependymoma 10.1 GFAP VIM
16 plexiform schwannoma 10.1 GFAP NF2
17 juvenile xanthogranuloma 10.1 BRAF VIM
18 spinal cancer 10.1 GFAP NF2
19 cornea cancer 10.1 GFAP NF2
20 clear cell meningioma 10.1 GFAP VIM
21 metanephric adenoma 10.1 BRAF VIM
22 ependymoblastoma 10.1 GFAP VIM
23 myxopapillary ependymoma 10.1 GFAP VIM
24 astroblastoma 10.1 GFAP VIM
25 chordoid glioma 10.1 GFAP NF2
26 melanotic neuroectodermal tumor 10.1 GFAP VIM
27 syringoma 10.1 GFAP VIM
28 amelanotic melanoma 10.1 BRAF VIM
29 benign ependymoma 10.1 GFAP NF2
30 atypical neurofibroma 10.1 GFAP NF2
31 malignant peritoneal mesothelioma 10.1 NF2 VIM
32 angiocentric glioma 10.1 GFAP VIM
33 medulloepithelioma 10.1 GFAP VIM
34 fibrous meningioma 10.1 NF2 VIM
35 trigeminal nerve neoplasm 10.1 GFAP NF2
36 pilomyxoid astrocytoma 10.1 BRAF GFAP
37 neurilemmoma of the fifth cranial nerve 10.1 GFAP NF2
38 melanotic medulloblastoma 10.1 GFAP SMARCB1
39 malignant ependymoma 10.1 GFAP NF2
40 nodular medulloblastoma 10.1 GFAP SMARCB1
41 granular cell tumor 10.0 GFAP VIM
42 cerebral ventricle cancer 10.0 GFAP SMARCB1
43 monosomy 22 10.0 NF2 SMARCB1
44 schwannomatosis 1 10.0 NF2 SMARCB1
45 spindle cell sarcoma 10.0 NF2 VIM
46 giant cell glioblastoma 10.0 BRAF GFAP
47 nevus of ota 10.0 BAP1 BRAF
48 choroid plexus cancer 10.0 GFAP SMARCB1
49 optic nerve glioma 10.0 GFAP VIM
50 small cell sarcoma 10.0 NF2 SMARCB1

Graphical network of the top 20 diseases related to Rhabdoid Meningioma:



Diseases related to Rhabdoid Meningioma

Symptoms & Phenotypes for Rhabdoid Meningioma

GenomeRNAi Phenotypes related to Rhabdoid Meningioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 9.13 BRAF NF2 VIM
2 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Rhabdoid Meningioma:

46 (show all 13)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.93 BAP1 BRAF GFAP NF2 SMARCB1 VIM
2 behavior/neurological MP:0005386 9.92 BRAF GFAP NF2 SMARCB1 VIM
3 cardiovascular system MP:0005385 9.91 BAP1 BRAF GFAP SMARCB1 VIM
4 immune system MP:0005387 9.91 BAP1 BRAF GFAP NF2 SMARCB1 VIM
5 embryo MP:0005380 9.88 BAP1 BRAF NF2 SMARCB1 VIM
6 mortality/aging MP:0010768 9.88 BAP1 BRAF GFAP NF2 SMARCB1 VIM
7 digestive/alimentary MP:0005381 9.8 BAP1 BRAF GFAP SMARCB1
8 muscle MP:0005369 9.77 BAP1 BRAF GFAP SMARCB1 VIM
9 nervous system MP:0003631 9.65 BRAF GFAP NF2 SMARCB1 VIM
10 neoplasm MP:0002006 9.62 BAP1 BRAF NF2 SMARCB1
11 reproductive system MP:0005389 9.55 BAP1 BRAF NF2 SMARCB1 VIM
12 respiratory system MP:0005388 9.26 BAP1 BRAF NF2 VIM
13 vision/eye MP:0005391 9.02 BRAF GFAP NF2 SMARCB1 VIM

Drugs & Therapeutics for Rhabdoid Meningioma

Drugs for Rhabdoid Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 71)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
2
Donepezil Approved Phase 3 120014-06-4 3152
3 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
4 Cola Phase 3,Phase 1
5 Central Nervous System Depressants Phase 3,Phase 2
6 Adjuvants, Anesthesia Phase 3
7 Liver Extracts Phase 3,Phase 1
8 Anesthetics, Intravenous Phase 3
9 Analgesics, Opioid Phase 3
10 Peripheral Nervous System Agents Phase 3,Phase 2
11 Anesthetics, General Phase 3
12 Analgesics Phase 3,Phase 2
13 Narcotics Phase 3
14 Anesthetics Phase 3
15 Neurotransmitter Agents Phase 3
16 Nootropic Agents Phase 3,Phase 2
17 Cholinergic Agents Phase 3
18 Cholinesterase Inhibitors Phase 3
19
Hydroxyurea Approved Phase 2 127-07-1 3657
20
Bevacizumab Approved, Investigational Phase 2 216974-75-3
21
Armodafinil Approved, Investigational Phase 2 112111-43-0
22
Modafinil Approved, Investigational Phase 2 68693-11-8 4236
23 Piracetam Approved, Investigational Phase 2 7491-74-9
24
Pregabalin Approved, Illicit, Investigational Phase 2 148553-50-8 5486971
25
Trabectedin Approved, Investigational Phase 2 114899-77-3 108150
26 Etiracetam Investigational Phase 2 33996-58-6
27
Vatalanib Investigational Phase 2 212141-54-3 151194
28 Imatinib Mesylate Phase 2 220127-57-1 123596
29 Nucleic Acid Synthesis Inhibitors Phase 2
30 Protein Kinase Inhibitors Phase 2
31 Antibodies, Monoclonal Phase 2
32 Immunoglobulins Phase 2
33 Angiogenesis Inhibitors Phase 2
34 Immunologic Factors Phase 2
35 Angiogenesis Modulating Agents Phase 2
36 Antibodies Phase 2
37 Anticonvulsants Phase 2,Phase 1
38 Wakefulness-Promoting Agents Phase 2
39 Central Nervous System Stimulants Phase 2
40 Cytochrome P-450 CYP3A Inducers Phase 2
41 Psychotropic Drugs Phase 2
42 Anti-Anxiety Agents Phase 2
43 Calcium, Dietary Phase 2
44 Neuroprotective Agents Phase 2
45 Tranquilizing Agents Phase 2
46 calcium channel blockers Phase 2
47 Protective Agents Phase 2
48 Alkylating Agents Phase 2,Phase 1
49 Antineoplastic Agents, Alkylating Phase 2,Phase 1
50
Verteporfin Approved, Investigational Phase 1 129497-78-5

Interventional clinical trials:

(show all 23)
# Name Status NCT ID Phase Drugs
1 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
2 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
3 Hydroxyurea With or Without Imatinib Mesylate in Treating Patients With Recurrent or Progressive Meningioma Unknown status NCT00904735 Phase 2 hydroxyurea;imatinib mesylate
4 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer Completed NCT00492089 Phase 2 bevacizumab;placebo
5 Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningioma Completed NCT00354913 Phase 2 hydroxyurea;imatinib mesylate
6 Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors Completed NCT01032200 Phase 2 Armodafinil
7 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2 levetiracetam;pregabalin
8 Vatalanib in Treating Patients With Recurrent or Progressive Meningioma Completed NCT00348790 Phase 2 vatalanib
9 Trabectedin for Recurrent Grade II/III Meningioma Active, not recruiting NCT02234050 Phase 2 Trabectedin
10 Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas Active, not recruiting NCT01125046 Phase 2
11 Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma Active, not recruiting NCT00895622 Phase 2
12 Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors Unknown status NCT00002647 Phase 1 verteporfin
13 RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma Completed NCT01119599 Phase 1 Gamma-Secretase Inhibitor RO4929097;Temozolomide
14 Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment Completed NCT00544284 Phase 1 bortezomib;temozolomide
15 MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma Completed NCT00020579 Phase 1 entinostat
16 Study of Tissue Samples From Patients With Glioma or Other Brain Tumors Completed NCT00967200
17 Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors Completed NCT00499798
18 Stress Reduction Program in Patients With Malignant Brain Tumors and Their Family Caregivers Completed NCT00376818 Not Applicable
19 Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders Completed NCT00255671
20 Oncological Care for Patients With Meningioma Not yet recruiting NCT02973256
21 Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases Terminated NCT02967380 Not Applicable Gadobenate Dimeglumine;Gadobutrol
22 Yoga Therapy in Treating Patients With Malignant Brain Tumors Terminated NCT01234805 Not Applicable
23 Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors Withdrawn NCT02194452 Not Applicable

Search NIH Clinical Center for Rhabdoid Meningioma

Genetic Tests for Rhabdoid Meningioma

Anatomical Context for Rhabdoid Meningioma

MalaCards organs/tissues related to Rhabdoid Meningioma:

41
Brain, Liver, Bone, Lymph Node, Cerebellum, Cervix, Pineal

Publications for Rhabdoid Meningioma

Articles related to Rhabdoid Meningioma:

(show top 50) (show all 96)
# Title Authors Year
1
Widespread Intra-abdominal Carcinomatosis from a Rhabdoid Meningioma after Placement of a Ventriculoperitoneal Shunt: A Case Report and Review of the Literature. ( 29682040 )
2018
2
Widespread Intra-abdominal Carcinomatosis from a Rhabdoid Meningioma after Placement of a Ventriculoperitoneal Shunt: A Case Report and Review of the Literature. ( 29492156 )
2018
3
Ectopic rhabdoid meningioma of the orbit in a child: case report and review of the literature. ( 29726794 )
2018
4
Giant Pediatric Rhabdoid Meningioma Associated with a Germline BAP1 Pathogenic Variation: A Rare Clinical Case. ( 29981911 )
2018
5
Intraparenchymal supratentorial papillary meningioma: a case report. ( 29564936 )
2018
6
Bilateral rhabdoid meningioma mimicking glioma: an unusual occurrence. ( 28860959 )
2017
7
Rhabdoid Meningioma of Brain - A Rare Aggressive Tumor. ( 28900335 )
2017
8
Rhabdoid Meningioma: Grading and Prognostic Significance of This Uncommon Variant. ( 28521039 )
2017
9
Rhabdoid Meningioma Arising Concurrent in Pulmonary and Intracranial with a Rare Malignant Clinical Progression: Case Report and Literature Review. ( 28797981 )
2017
10
Survival benefit of postoperative radiation in papillary meningioma: Analysis of the National Cancer Data Base. ( 29123457 )
2017
11
Recurrent rhabdoid meningioma with lymph node, pulmonary and bone metastases: a diagnostic and therapeutic challenge. ( 26875176 )
2016
12
Recurrent skull base rhabdoid meningioma in an adolescent patient. ( 27841231 )
2016
13
Leptomeningeal Dissemination of Intraventricular Rhabdoid Meningioma: Imaging Findings. ( 27161477 )
2016
14
Erratum: A rare intracranial tumor consisting of malignant anaplastic and papillary meningioma subtypes. ( 27280054 )
2016
15
A rare intracranial tumor consisting of malignant anaplastic and papillary meningioma subtypes. ( 27382521 )
2016
16
Primary intraspinal papillary meningioma: a rare aggressive variant of meningioma. ( 26972623 )
2016
17
A rare intracranial tumor consisting of malignant anaplastic and papillary meningioma subtypes. ( 26981322 )
2016
18
Papillary meningioma: an aggressive variant meningioma with clinical features and treatment: a retrospective study of 10 cases. ( 26299848 )
2016
19
Rhabdoid meningioma: report of two cases. ( 25859490 )
2015
20
Rhabdoid meningioma in the petroclival region: An atypical meningioma in an atypical site. ( 26425167 )
2015
21
Metastatic rhabdoid meningioma of the parotid - Mimicking primary salivary gland neoplasm. ( 25528037 )
2015
22
Rhabdoid meningioma lacking malignant features: Report of a rare case with review of literature. ( 25972960 )
2015
23
Papillary meningioma in the dog: A clinicopathological case series study. ( 25847284 )
2015
24
Rhabdoid papillary meningioma treated with 177Lu DOTATATE PRRT. ( 25608146 )
2015
25
Systematic Analysis of Outcomes for Surgical Resection and Radiotherapy in Patients with Papillary Meningioma. ( 26225311 )
2015
26
Papillary meningioma of the jugular foramen: A case report. ( 26788186 )
2015
27
Aggressive rhabdoid meningioma with osseous, papillary and chordoma-like appearance. ( 24702318 )
2014
28
Rhabdoid meningioma: analysis of one case. ( 23974967 )
2014
29
Metastatic Rhabdoid Meningioma with BRAF V600E Mutation and Good Response to Personalized Therapy: Case Report and Review of the Literature. ( 25116269 )
2014
30
Intracerebral cystic rhabdoid papillary meningioma in an 11-year-old patient. ( 24952236 )
2014
31
Magnetic resonance imaging findings of intracranial papillary meningioma: a study on eight cases. ( 24993640 )
2014
32
Papillary meningioma with vital abnormal vessels. ( 25006926 )
2014
33
Papillary meningioma: clinical and histopathological observations. ( 23638219 )
2013
34
Intracranial papillary meningioma: a clinicopathologic study of 30 cases at a single institution. ( 23921710 )
2013
35
Crush cytology of a primary intraspinal rhabdoid papillary meningioma: a case report. ( 24021412 )
2013
36
Primary calcified rhabdoid meningioma of the cranio-cervical junction: A case report and review of literature. ( 23741128 )
2012
37
Identification of CD105 (endoglin)-positive stem-like cells in rhabdoid meningioma. ( 21894449 )
2012
38
Intraparenchymal papillary meningioma of brainstem: case report and literature review. ( 22236763 )
2012
39
Hemorrhagic onset of rhabdoid meningioma after initiating treatment for infertility. ( 22350616 )
2012
40
Pediatric rhabdoid meningioma: a morphological, immunohistochemical, ultrastructural and molecular case study. ( 20408963 )
2011
41
Intraspinal rhabdoid meningioma metastasis to the liver. ( 21349724 )
2011
42
Rhabdoid papillary meningioma: a clinicopathologic case series study. ( 21382093 )
2011
43
Papillary meningioma with leptomeningeal seeding. ( 21519503 )
2011
44
Papillary meningioma: a rare malignant variant. ( 21623111 )
2011
45
Rhabdoid meningioma: rapid intraoperative diagnosis on squash smears. ( 19941363 )
2010
46
Clinicopathologic analysis of rhabdoid meningioma. ( 20537897 )
2010
47
Rhabdoid meningioma presenting with subependymal and diffuse meningeal involvement but no mass lesion. ( 20800496 )
2010
48
Rhabdoid meningioma in an eight-year-old child. ( 20514784 )
2010
49
Intracerebral cystic rhabdoid meningioma. ( 19427788 )
2009
50
Cystic papillary meningioma with subarachnoid dissemination: a case report and review of the literature. ( 19307065 )
2009

Variations for Rhabdoid Meningioma

Expression for Rhabdoid Meningioma

Search GEO for disease gene expression data for Rhabdoid Meningioma.

Pathways for Rhabdoid Meningioma

Pathways related to Rhabdoid Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.3 BRAF NF2
2 11.29 BAP1 NF2 VIM
3
Show member pathways
11.19 GFAP VIM
4 10.85 GFAP VIM

GO Terms for Rhabdoid Meningioma

Cellular components related to Rhabdoid Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 9.13 BRAF NF2 VIM
2 cell body GO:0044297 8.8 BRAF GFAP NF2

Biological processes related to Rhabdoid Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.61 BAP1 NF2 SMARCB1
2 negative regulation of neuron projection development GO:0010977 9.4 GFAP VIM
3 positive regulation of stress fiber assembly GO:0051496 9.37 BRAF NF2
4 long-term synaptic potentiation GO:0060291 9.32 BRAF GFAP
5 intermediate filament organization GO:0045109 9.26 GFAP VIM
6 astrocyte development GO:0014002 9.16 GFAP VIM
7 Bergmann glial cell differentiation GO:0060020 8.96 GFAP VIM
8 intermediate filament-based process GO:0045103 8.62 GFAP VIM

Molecular functions related to Rhabdoid Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 GFAP VIM

Sources for Rhabdoid Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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