MCID: RHM009
MIFTS: 34

Rheumatoid Lung Disease

Categories: Respiratory diseases, Immune diseases, Bone diseases

Aliases & Classifications for Rheumatoid Lung Disease

Summaries for Rheumatoid Lung Disease

MalaCards based summary : Rheumatoid Lung Disease, also known as rheumatoid lung, is related to arthritis and rheumatoid arthritis. An important gene associated with Rheumatoid Lung Disease is MMP3 (Matrix Metallopeptidase 3), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Allograft rejection. Affiliated tissues include lung.

Wikipedia : 76 Rheumatoid Lung Disease, also called Rheumatoid Lung is a disease of the lung associated with RA,... more...

Related Diseases for Rheumatoid Lung Disease

Diseases related to Rheumatoid Lung Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 arthritis 28.7 IL17A MMP3 TNF TNFRSF1B
2 rheumatoid arthritis 27.7 CD40LG IL17A MMP3 TNF TNFRSF1B
3 trench fever 10.6 CD40LG TNF
4 encephalitozoonosis 10.6 CD40LG TNF
5 miller fisher syndrome 10.6 CD40LG TNF
6 osteosclerotic myeloma 10.6 CD40LG TNF
7 jejunoileitis 10.6 CD40LG TNF
8 monoclonal gammopathy of uncertain significance 10.6 CD40LG TNF
9 coccidiosis 10.5 CD40LG TNF
10 hemorrhagic fever 10.5 CD40LG TNF
11 streptococcal meningitis 10.5 CD40LG TNF
12 pustulosis palmaris et plantaris 10.5 CD40LG TNF
13 scrub typhus 10.5 CD40LG TNF
14 lichen disease 10.5 CD40LG TNF
15 orbital granuloma 10.5 CD40LG MUC1
16 multiple cranial nerve palsy 10.5 CD40LG MMP3
17 middle ear disease 10.5 CD40LG TNF
18 plasmodium vivax malaria 10.5 CD40LG TNF
19 hepatitis e 10.5 CD40LG TNF
20 progressive multifocal leukoencephalopathy 10.5 CD40LG TNF
21 commensal bacterial infectious disease 10.5 CD40LG TNF
22 q fever 10.5 CD40LG TNF
23 skin sarcoidosis 10.5 TNF TNFRSF1B
24 churg-strauss syndrome 10.5 CD40LG TNF
25 chronic gonococcal salpingitis 10.5 TNF TNFRSF1B
26 scleral disease 10.5 TNF TNFRSF1B
27 pustulosis of palm and sole 10.5 TNF TNFRSF1B
28 chickenpox 10.5 CD40LG MUC1
29 peroneal neuropathy 10.5 TNF TNFRSF1B
30 hemorrhagic fever with renal syndrome 10.4 CD40LG TNF
31 periodic fever, familial, autosomal dominant 10.4 TNF TNFRSF1B
32 rheumatic fever 10.4 CD40LG TNF
33 louping ill 10.4 CD40LG ERVW-1
34 pulmonary hemosiderosis 10.4 CD40LG MUC1
35 sweat gland disease 10.4 TNF TNFRSF1B
36 idiopathic neutropenia 10.4 CD40LG TNF
37 kyasanur forest disease 10.4 CD40LG ERVW-1
38 chikungunya 10.4 CD40LG TNF
39 cutaneous lupus erythematosus 10.4 CD40LG TNF
40 post-transplant lymphoproliferative disease 10.4 TNF TNFRSF1B
41 iritis 10.4 CD40LG TNFRSF1B
42 mixed connective tissue disease 10.4 CD40LG TNF
43 fasciitis 10.4 MUC1 TNF
44 murray valley encephalitis 10.4 CD40LG ERVW-1
45 legionellosis 10.4 CD40LG TNF
46 chronic salpingitis 10.4 TNF TNFRSF1B
47 phlebotomus fever 10.4 CD40LG ERVW-1
48 transient arthritis 10.4 CD40LG ERVW-1
49 leptospirosis 10.4 CD40LG TNF
50 lung disease 10.4

Comorbidity relations with Rheumatoid Lung Disease via Phenotypic Disease Network (PDN):


Acute Cystitis Bronchitis
Deficiency Anemia Heart Disease
Idiopathic Interstitial Pneumonia Osteoporosis
Postinflammatory Pulmonary Fibrosis Respiratory Failure
Rheumatoid Arthritis

Graphical network of the top 20 diseases related to Rheumatoid Lung Disease:



Diseases related to Rheumatoid Lung Disease

Symptoms & Phenotypes for Rheumatoid Lung Disease

Drugs & Therapeutics for Rheumatoid Lung Disease

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Active Rheumatoid Arthritis Terminated NCT01261403 Phase 2 Vehicle Controlled Placebo
2 Analysis of Respiratory Mechanics in Patients With Rheumatoid Arthritis Unknown status NCT01641705

Search NIH Clinical Center for Rheumatoid Lung Disease

Genetic Tests for Rheumatoid Lung Disease

Anatomical Context for Rheumatoid Lung Disease

MalaCards organs/tissues related to Rheumatoid Lung Disease:

41
Lung

Publications for Rheumatoid Lung Disease

Articles related to Rheumatoid Lung Disease:

(show all 35)
# Title Authors Year
1
Diagnostic performances of high resolution trans-thoracic lung ultrasonography in pulmonary alveoli-interstitial involvement of rheumatoid lung disease. ( 23936595 )
2013
2
Rheumatoid lung disease: prognostic analysis of 54 biopsy-proven cases. ( 22560113 )
2012
3
Massive spontaneous hemopneumothorax complicating rheumatoid lung disease. ( 17383372 )
2007
4
Rheumatoid lung disease as seen on PET/CT scan. ( 17710040 )
2007
5
Rheumatoid lung disease. ( 17684286 )
2007
6
Role of KL-6 in evaluating the disease severity of rheumatoid lung disease: comparison with HRCT. ( 15526815 )
2004
7
Gold-induced pulmonary disease: clinical features, outcome, and differentiation from rheumatoid lung disease. ( 9116980 )
1997
8
Rheumatoid arthritis: classical rheumatoid lung disease. ( 8519069 )
1993
9
Bronchoalveolar lavage in patients with mild and severe rheumatoid lung disease. ( 2169654 )
1990
10
Spontaneous pneumothorax complicating rheumatoid lung disease. ( 2638671 )
1989
11
CT appearances of rheumatoid lung disease. ( 6470256 )
1984
12
Bilateral pneumothoraces and pleural effusions in rheumatoid lung disease. ( 6710432 )
1984
13
Bilateral pneumothoraces and pleural effusions complicating rheumatoid lung disease. ( 6857576 )
1983
14
Rheumatoid lung disease, pneumothorax, and eosinophilia. ( 7073341 )
1982
15
Broncho-pleural fistula complicating rheumatoid lung disease. ( 7100049 )
1982
16
Rheumatoid lung disease. (A clinical, physiological and histological study in 33 patients). ( 7209294 )
1980
17
Roentgenogram of the month. Productive cough and hemoptysis in rheumatoid lung disease. ( 1269277 )
1976
18
Cavitary pulmonary lymphosarcoma masquerading as rheumatoid lung disease. ( 1083917 )
1976
19
Rheumatoid lung disease; granulomas, fibrosis, pulmonary effusion. ( 1055882 )
1975
20
Rheumatoid lung disease with pulmonary fibrosis necrobiotic nodules and pleural effusion. ( 4715613 )
1973
21
Scar cancer of lung complicating rheumatoid lung disease. ( 4357248 )
1973
22
Interstitial rheumatoid lung disease. A reassessment and review of the literature. ( 5066501 )
1972
23
Empyema in rheumatoid lung disease. ( 5315083 )
1971
24
Cytoplasmic lamellar inclusions resembling tissue mast cel granules in suspected rheumatoid lung disease. ( 5347074 )
1969
25
Rheumatoid lung disease. ( 6037347 )
1967
26
Pyopneumothorax in rheumatoid lung disease. ( 5914995 )
1966
27
Rheumatoid lung disease with report of a case. ( 5924576 )
1966
28
Cholesterol pleural effusion in rheumatoid lung disease. ( 5972525 )
1966
29
Rheumatoid lung disease with cavitary nodules, pneumothorax and eosinophilia. ( 5918107 )
1966
30
PYOPNEUMOTHORAX COMPLICATING RHEUMATOID LUNG DISEASE. ( 14267640 )
1965
31
RHEUMATOID LUNG DISEASE. ( 14274833 )
1965
32
Diffuse interstitial pulmonary fibrosis associated with arthritis, with comments on the definition of rheumatoid lung disease. ( 13886829 )
1962
33
Rheumatoid lung disease. A case report which includes respiratory function studies and a lung biopsy. ( 13718774 )
1961
34
Nodular rheumatoid lung disease. ( 13742213 )
1961
35
Rheumatoid lung disease: report of a case which developed in childhood. ( 13804478 )
1959

Variations for Rheumatoid Lung Disease

Expression for Rheumatoid Lung Disease

Search GEO for disease gene expression data for Rheumatoid Lung Disease.

Pathways for Rheumatoid Lung Disease

Pathways related to Rheumatoid Lung Disease according to GeneCards Suite gene sharing:

(show all 21)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.54 CD40LG IL17A MMP3 MUC1 TNF TNFRSF1B
2
Show member pathways
12.52 CD40LG IL17A TNF TNFRSF1B
3
Show member pathways
12.37 CD40LG TNF TNFRSF1B
4
Show member pathways
12.14 CD40LG TNF TNFRSF1B
5 12.14 CD40LG IL17A TNF TNFRSF1B
6
Show member pathways
12.13 CD40LG IL17A TNF
7
Show member pathways
12 IL17A MMP3 TNF
8 11.9 CD40LG TNF TNFRSF1B
9 11.61 MMP3 TNF TNFRSF1B
10 11.5 IL17A MMP3 TNF
11 11.32 TNF TNFRSF1B
12
Show member pathways
11.3 CD40LG TNF TNFRSF1B
13
Show member pathways
11.28 TNF TNFRSF1B
14 11.27 TNF TNFRSF1B
15 11.26 CD40LG TNF
16 11.15 MMP3 MUC1
17
Show member pathways
11.13 CD40LG MMP3 TNF
18 11.08 IL17A MMP3 MUC1 TNF TNFRSF1B
19 11.05 CD40LG TNFRSF1B
20 11.03 TNF TNFRSF1B
21 11.02 IL17A TNF

GO Terms for Rheumatoid Lung Disease

Cellular components related to Rheumatoid Lung Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 CD40LG IL17A MMP3 MUC1 TNF
2 external side of plasma membrane GO:0009897 9.13 CD40LG IL17A TNF
3 extracellular region GO:0005576 9.1 CD40LG IL17A MMP3 MUC1 TNF TNFRSF1B

Biological processes related to Rheumatoid Lung Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.62 CD40LG IL17A TNF TNFRSF1B
2 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.46 TNF TNFRSF1B
3 inflammatory response GO:0006954 9.46 CD40LG IL17A TNF TNFRSF1B
4 extrinsic apoptotic signaling pathway GO:0097191 9.43 TNF TNFRSF1B
5 tumor necrosis factor-mediated signaling pathway GO:0033209 9.43 CD40LG TNF TNFRSF1B
6 positive regulation of osteoclast differentiation GO:0045672 9.4 IL17A TNF
7 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.37 TNF TNFRSF1B
8 cytokine-mediated signaling pathway GO:0019221 9.02 IL17A MMP3 MUC1 TNF TNFRSF1B
9 regulation of immunoglobulin secretion GO:0051023 8.96 CD40LG TNF

Molecular functions related to Rheumatoid Lung Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor receptor binding GO:0005164 8.96 CD40LG TNF
2 cytokine activity GO:0005125 8.8 CD40LG IL17A TNF

Sources for Rheumatoid Lung Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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