MCID: RHN004
MIFTS: 62

Rhinitis

Categories: Bone diseases, Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Rhinitis

MalaCards integrated aliases for Rhinitis:

Name: Rhinitis 12 29 55 44 15 73
Runny Nose 12 3

Classifications:



External Ids:

Disease Ontology 12 DOID:4483
MeSH 44 D012220
NCIt 50 C34986
SNOMED-CT 68 70076002
UMLS 73 C0035455

Summaries for Rhinitis

CDC : 3 Sore throat and runny nose are usually the first signs of a cold, followed by coughing and sneezing. Most people recover in about 7-10 days. You can help reduce your risk of getting a cold: wash your hands often, avoid close contact with sick people, and don’t touch your face with unwashed hands.

MalaCards based summary : Rhinitis, also known as runny nose, is related to allergic rhinitis and ige responsiveness, atopic, and has symptoms including rhinorrhea, sneezing and sinus congestion. An important gene associated with Rhinitis is IL13 (Interleukin 13), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Allegra and Allegra-D have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells, and related phenotypes are growth/size/body region and hematopoietic system

Disease Ontology : 12 A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.

Wikipedia : 76 Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose.... more...

Related Diseases for Rhinitis

Diseases in the Rhinitis family:

Chronic Rhinitis

Diseases related to Rhinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 308)
# Related Disease Score Top Affiliating Genes
1 allergic rhinitis 33.2 CCL11 CXCL8 EPX FOXJ1 HRH1 ICAM1
2 ige responsiveness, atopic 32.9 IGHE IL13 IL4 IL4R IL5 RNASE3
3 pollen allergy 32.4 EPX ICAM1 IL13 IL4R IL5 RNASE3
4 common cold 32.0 CCL11 CCL5 CXCL8 ICAM1 IL13 IL5
5 respiratory syncytial virus infectious disease 32.0 CCL5 IL13 IL5
6 allergic conjunctivitis 31.9 CCL11 CXCL8 HRH1 ICAM1 IL13 IL4
7 giant papillary conjunctivitis 31.8 CCL11 CXCL8 IL4 RNASE3
8 bronchiolitis 31.4 CCL11 CCL5 CXCL8 IGHE IL13 IL4
9 dermatitis 31.1 CCL11 IGHE IL13 IL4 IL5
10 sinusitis 30.9 CXCL8 CYSLTR1 IL4R IL5 RNASE3
11 urticaria 30.9 HRH1 IGHE RNASE3
12 pneumonia 30.6 CCL11 CCL5 CXCL8 IL13 IL5
13 otitis media 30.6 CCL11 CXCL8 IGHE IL4 RNASE3
14 food allergy 30.5 EPX IL13 IL4 IL5 RNASE3
15 allergic asthma 30.5 CCL11 CCL5 EPX IGHE IL13 IL4
16 bronchitis 30.4 CCL11 CXCL8 IL5 RNASE3
17 dermatitis, atopic 30.4 CCL11 CCL5 CXCL8 CYSLTR1 EPX HRH1
18 conjunctivitis 30.3 CCL11 CXCL8 EPX HRH1 ICAM1 IL13
19 esophagitis, eosinophilic, 1 30.3 CCL11 IL13 IL5
20 pulmonary disease, chronic obstructive 30.2 CCL11 CCL5 CXCL8 IL13 NR3C1 RNASE3
21 hypereosinophilic syndrome 30.2 CCL11 EPX IGHE IL13 IL4 IL5
22 allergic bronchopulmonary aspergillosis 30.2 EPX IL4 IL5
23 esophagitis 30.2 CCL11 CXCL8 IL13 IL5
24 intrinsic asthma 30.1 IL4 IL5 RNASE3
25 respiratory allergy 30.1 CCL11 IGHE IL13 IL4 IL4R IL5
26 blepharoconjunctivitis 29.9 CCL11 IL4 RNASE3
27 asthma 29.9 CCL11 CCL5 CXCL8 CYSLTR1 EPX HRH1
28 milk allergy 29.9 IL4 IL5 RNASE3
29 vulvovaginitis 29.8 CCL11 CCL5 CXCL8
30 cough variant asthma 29.8 IL4 IL5 NGF RNASE3
31 latex allergy 29.8 IGHE IL13 IL4 IL5 RNASE3
32 leishmaniasis 29.8 CXCL8 IL13 IL4 IL5
33 lung disease 29.7 CCL5 CXCL8 IL13 IL5 RNASE3
34 keratoconjunctivitis 29.6 CCL11 CXCL8 ICAM1 IL13 IL4 IL5
35 allergic hypersensitivity disease 29.4 CCL11 CCL5 EPX HRH1 IGHE IL13
36 vernal keratoconjunctivitis 29.4 CCL11 CCL5 ICAM1 IL13 IL4 IL5
37 rheumatoid arthritis 29.4 CCL5 CXCL8 ICAM1 IL4 VCAM1
38 chronic rhinitis 12.6
39 vasomotor rhinitis 12.6
40 atrophic rhinitis 12.6
41 asthma-related traits 4 11.9
42 olfactory neuroblastoma 11.4
43 actinobacillosis 11.3
44 measles 11.3
45 influenza 11.2
46 hemicrania continua 11.2
47 swine influenza 11.1
48 pertussis 11.1
49 bordetella parapertussis whooping cough 11.1
50 croup 11.1

Graphical network of the top 20 diseases related to Rhinitis:



Diseases related to Rhinitis

Symptoms & Phenotypes for Rhinitis

UMLS symptoms related to Rhinitis:


rhinorrhea, sneezing, sinus congestion, nasal congestion (finding), nasal irritation, posterior rhinorrhea

MGI Mouse Phenotypes related to Rhinitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.03 FOXJ1 HRH1 ICAM1 IL13 IL4 IL4R
2 hematopoietic system MP:0005397 9.93 CCL11 CCL5 EPX HRH1 ICAM1 IL13
3 digestive/alimentary MP:0005381 9.87 FOXJ1 ICAM1 IL13 IL4 IL4R IL5
4 immune system MP:0005387 9.77 CCL11 CCL5 CYSLTR1 EPX HRH1 ICAM1
5 respiratory system MP:0005388 9.23 CCL11 CYSLTR1 FOXJ1 IL13 IL4 IL4R

Drugs & Therapeutics for Rhinitis

FDA approved drugs:

(show all 18)
# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Allegra 18 FEXOFENADINE HYDROCHLORIDE Hoechst Marion Roussel July 1996
2
Allegra-D 18 FEXOFENADINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE Hoechst Marion Roussel March 1998
3
Astelin nasal spray 18 AZELASTINE HYDROCHLORIDE Wallace Laboratories November 1996
4
Atrovent 18 IPRATROPIUM BROMIDE Boehringer Ingelheim January 1996
5
Clarinex 18 DESLORATADINE Schering-Plough February 2002
6
Clemastine fumarate syrup 18 CLEMASTINE FUMARATE Morton Grove Pharmaceuticals March 1998
7
Dymista 18 AZELASTINE HYDROCHLORIDE; FLUTICASONE PROPIONATE Meda Pharmaceuticals Inc May 2012
8
Flonase Nasal Spray 18 FLUTICASONE PROPIONATE GlaxoSmithKline November 1997
9
Grastek 18 Timothy Grass Pollen Allergen Extract Merck April 2014
10
Nasacort AQ Nasal Spray 18 TRIAMCINOLONE ACETONIDE Phone-Poulenc Rorer October 1997
11
Oralair 18 Greer Labs April 2014
12
Patanase 18 OLOPATADINE HYDROCHLORIDE Alcon April 2008
13
Qnasl 18 BECLOMETHASONE DIPROPIONATE Teva Pharmaceutical March 2012
14
Ragwitek 18 Merck April 2014
15
Rhinocort Aqua Nasal Spray 18 BUDESONIDE AstraZeneca October 1999
16
Tri-Nasal Spray 18 Muro Pharmaceutical February 2000
17
Xyzal 18 LEVOCETIRIZINE DIHYDROCHLORIDE UCB May 2007
18
Zyrtec 18 CETIRIZINE HYDROCHLORIDE Pfizer December 1995

Drugs for Rhinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 402)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-45-6, 75614-87-8 774
2
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
3
mometasone furoate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83919-23-7
4
Dexlansoprazole Approved, Investigational Phase 4 103577-45-3, 138530-94-6 9578005
5
Capsaicin Approved Phase 4,Phase 2,Phase 1,Not Applicable 404-86-4 1548943
6
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 90566-53-3 62924
7
Azelastine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58581-89-8 2267
8
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 158966-92-8 5281040
9
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83881-51-0 2678
10
Nitric Oxide Approved Phase 4,Phase 1,Phase 2,Not Applicable 10102-43-9 145068
11
Levocetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 130018-77-8 1549000
12
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90-82-4 7028
13
Xylometazoline Approved, Investigational Phase 4,Not Applicable 526-36-3 5709
14
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
15
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3 2921-57-5
16
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
17
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3 302-25-0
18
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 299-42-3 9294
19
Desloratadine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 100643-71-8 124087
20
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-42-7 6041
21
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1491-59-4 4636
22
Loratadine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 79794-75-5 3957
23
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
24
Omalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 242138-07-4
25
Ciclesonide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 141845-82-1, 126544-47-6 444033
26
Budesonide Approved Phase 4,Phase 3,Phase 2,Not Applicable 51333-22-3 63006 5281004
27
Fexofenadine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 83799-24-0 3348
28
Resveratrol Approved, Experimental, Investigational Phase 4,Phase 3 501-36-0 445154
29
Triamcinolone Approved, Vet_approved Phase 4,Phase 3 124-94-7 31307
30
Adenosine Approved, Investigational Phase 4,Phase 2,Phase 1 58-61-7 60961
31
Doxazosin Approved Phase 4 74191-85-8 3157
32
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 329-65-7 838
33
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816
34
Ethanol Approved Phase 4,Phase 2,Phase 1,Not Applicable 64-17-5 702
35
Diphenhydramine Approved, Investigational Phase 4,Phase 3,Phase 1 147-24-0, 58-73-1 3100
36
Promethazine Approved, Investigational Phase 4,Phase 3,Phase 1 60-87-7 4927
37
Prazosin Approved Phase 4 19216-56-9 4893
38
Theophylline Approved Phase 4,Phase 2 58-55-9 2153
39
Ebastine Approved, Investigational Phase 4 90729-43-4 3191
40
Pimecrolimus Approved, Investigational Phase 4 137071-32-0 6447131 17753757
41
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
42
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Not Applicable 50-14-6 5280793
43
Vitamin D3 Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Not Applicable 67-97-0 5280795 6221
44
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 1406-16-2
45
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2 77-92-9 311
46
Prednisolone hemisuccinate Experimental Phase 4,Phase 3 2920-86-7
47
Tranilast Investigational Phase 4 53902-12-8 93543
48 Andrographolide Investigational Phase 4 5508-58-7
49 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Histamine H1 Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 1124)
# Name Status NCT ID Phase Drugs
1 Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis Unknown status NCT02014623 Phase 4 Control
2 Efficacy of Allergen Immunotherapy for Allergic Rhinitis in Thais Unknown status NCT01115595 Phase 4
3 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
4 Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites Unknown status NCT01052610 Phase 4 sublingual house dust mites allergen extract;placebo in sublingual applicator
5 Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis Unknown status NCT00825656 Phase 4 Sinol or Sinol-M nasal spray
6 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Unknown status NCT02288156 Phase 4 Capsaicin;placebo
7 Evaluating Factors Involved in Dymista's Superior Clinical Efficacy to Fluticasone Propionate in the Treatment of Seasonal Allergic Rhinitis Unknown status NCT02402465 Phase 4 Placebo;Fluticasone propionate;Fluticasone/Azelastine nasal spray
8 Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis Unknown status NCT00488176 Phase 4 montelukast;cetirizine;montelukast and cetirizine;placebo
9 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
10 AZELASTINE/FLUTICASONE (AZE/FLU) Nasal Spray on Symptom Control, Nasal Mediators and Nasal Hyperresponsiveness in Allergic Rhinitis (AR) Unknown status NCT02238353 Phase 4 azelastine + fluticasone;Placebo
11 Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy Unknown status NCT01062139 Phase 4 Xarlin (Levocetirizine);Cosalin (Petasites hybridus CO2 extract)
12 4"S" - Seasonal Symptoms Suppression Study Unknown status NCT02557269 Phase 4 Xylometazoline - intranasal application;Azelastine - intranasal application;Mometasone furoate - intranasal application;Hydroxyl-propyl-methyl cellulose powder - intranasal application;Bilastine 20 mg;Prednisolone 5 mg
13 POLlinosis and Exhaled Breath Temperature Unknown status NCT01785394 Phase 4 5 grass allergen extract
14 Anti-inflammatory H1 Antihistamines Allergic Rhinitis Completed NCT02507635 Phase 4 Levocetirizine;Desloratadine
15 Sunovion Growth Study Pediatric Subjects With Mild Asthma & Allergic Rhinitis Completed NCT01550471 Phase 4 Alvesco/Omnaris, QVAR/Beconase, Placebo/Placebo;Alvesco/Omnaris, Placebo/Placebo, QVAR/Beconase;QVAR/Beconase, Alvesco/Omnaris, Placebo/Placebo;QVAR/Beconase, Placebo/Placebo, Alvesco/Omnaris;Placebo/Placebo, Alvesco/Omnaris, QVAR/Beconase;Placebo/Placebo, QVAR/Beconase, Alvesco/Omnaris
16 Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction Completed NCT01847131 Phase 4 oxymetazoline;Placebo nasal spray
17 Quality of Life in Patients With Allergic Rhinitis: Clinical Trial With Bilastine or Loratadine Completed NCT02513290 Phase 4 Bilastine;Loratadine
18 Comparison of Effectiveness and Safety of Sublingual Immunotherapy in Children With Allergic Rhinitis Completed NCT00698594 Phase 4
19 Effectiveness Of Therapy With A Thermal Water Nasal Aerosol In Children With Seasonal Allergic Rhinitis Completed NCT01326247 Phase 4
20 Nasal Budesonide Efficacy on Nasal FeNO in Children With Allergic Rhinitis Completed NCT02409563 Phase 4 Budesonide nasal spray (100 mcg bid);Budesonide nasal spray (50 mcg bid
21 Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis Completed NCT02551536 Phase 4 Montelukast;Fexofenadine;Levocetrizine
22 Efficacy & Safety of Loratadine-Betamethasone Oral Solution for Treatment of Severe Perennial Allergic Rhinitis in Children (Study P03428) Completed NCT00963573 Phase 4 Loratadine;Betamethasone
23 Nebulized Resveratrol Plus Carboxymethyl-β-Glucan for Reducing IL-5 in Children With Allergic Rhinitis Completed NCT03349619 Phase 4 Resveratrol plus Carboxymethyl-β-Glucan;Placebo
24 Nebulized Beclometasone Dipropionate Improves Nasal Patency in Children With Allergic Rhinitis Completed NCT02646904 Phase 4 Nasal Beclomethasone Dipropionate;CERCHIO 10 mg/ml OS
25 Assessment of Intranasal Steroids in Allergic Rhinitis When Used Alone or in Combination With an Oral Antihistamine (Study P03270) Completed NCT00834119 Phase 4 Mometasone furoate;Mometasone furoate
26 Efficacy and Safety of Lectranal® in Treatment of Seasonal Allergic Rhinitis Symptoms Completed NCT00460538 Phase 4
27 A Clinical Study To Test A Nasal Spray (Fluticasone Furoate Nasal Spray) For The Treatment Of Perennial (Year-round) Allergic Rhinitis Completed NCT00609674 Phase 4 Fluticasone furoate nasal spray;Placebo
28 Efficacy and Tolerability of a Topical Microemulsion in Patients With Allergic Rhinitis Due to Sensitization to Pollen Completed NCT01478425 Phase 4
29 Comparison of Olopatadine 0.6% and Fluticasone Proprionate 50mcg Nasal Sprays in a Two Week Seasonal Allergic Rhinitis Trial Completed NCT00691665 Phase 4 Olopatadine HCL Nasal Spray, 0.6%;Fluticasone Propionate Nasal Spray, 50 mcg
30 Montelukast in Mild Asthmatic Children With Allergic Rhinitis (0476-367) Completed NCT00442559 Phase 4 montelukast sodium;inhaled corticosteroid
31 Study of Triamcinolone Acetonide on the Growth Velocity of Children, Ages 3 to 9, With Perennial Allergic Rhinitis (PAR) Completed NCT00449072 Phase 4 TAA-AQ, Nasacort® AQ;Claritin®
32 A Phase-IV, Open-label Study to Evaluate Safety/Tolerability of Once-daily AVAMYS (TM) Aqueous Nasal Spray 110mcg Among Vietnamese Adult Patients With Established Perennial Allergic Rhinitis Completed NCT01270958 Phase 4 Avamys aqueous nasal spray 110mcg
33 Levocetirizine 5 mg: Reduction of Symptoms, Airway Resistance and Sleep Impairment in Persistent Allergic Rhinitis Completed NCT00355771 Phase 4 Levocetirizine;Placebo
34 Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects Completed NCT00295022 Phase 4 Placebo;Montelukast;Levocetirizine
35 Allergic Rhinitis Changes the Sinus Microbiome Completed NCT01852513 Phase 4 QNASL;Placebo nasal spray
36 Effectiveness of Individualized Homeopathic Treatment in Perennial Allergic Rhinitis Completed NCT00822406 Phase 4 homeopathic medicine;placebo
37 The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine Completed NCT02477293 Phase 4 Hyeonggaeyeongyo-tang
38 Comparison of the Effects of Nasal Steroids and Montelukast on Olfactory Functions in Patients With Allergic Rhinitis Completed NCT02565212 Phase 4 Montelukast,mometazon froat
39 To Evaluate Adenosine Monophosphate and Allergen Challenge in Allergic Rhinitis Completed NCT00679250 Phase 4 levocetirizine;placebo to levocetirizine
40 A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis Completed NCT00682643 Phase 4 fluticasone furoate nasal spray;vehicle placebo nasal spray
41 Fluticasone and Salmeterol in Allergic Rhinitis Completed NCT01388595 Phase 4 FLUTICASONE PROPRIONATE;Salmeterol;PLACEBO
42 Alpha-Blockers in Allergic Rhinitis (MAN 01) Completed NCT01946035 Phase 4 Doxazosin XL
43 POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis) Completed NCT00160537 Phase 4 Levocetirizine
44 Effects of Hypertonic Saline Solution (NACL 3%+NAHCO3) on Nasal Inflammation in Children With AR. RinASol- Pilot Study Completed NCT02729012 Phase 4 hypertonic saline solution (NACL 3%+NAHCO3)
45 Investigation of the Efficacy and Safety of Concomitant Administration of Ciclesonide Nasal Spray and Azelastine Nasal Spray in Patients (18 Years or Older) With Perennial Allergic Rhinitis (PAR) Not Adequately Controlled on an Intranasal Corticosteroid or Antihistamine Monotherapy (BY9010/M1-490) Completed NCT00806754 Phase 4 Ciclesonide nasal spray + placebo Azelastine;Ciclesonide nasal spray + Azelastine
46 Children, Perennial Allergic Rhinitis (PAR), l-t Growth Completed NCT00641212 Phase 4 Budesonide;Placebo
47 The Role of Montelukast in Rhinitis and Sleep Completed NCT00590772 Phase 4 montelukast;placebo
48 A Randomized, Placebo Controlled Study to Determine the Efficacy and Speed of a Nasal Spray in Allergen Induced Seasonal Allergic Rhinitis Completed NCT00561717 Phase 4 Azelastine and placebo;Loratadine and Placebo;Cetirizine and Placebo;Placebo and Placebo (spray and Tablet)
49 A Study of Onset of Action of Loratadine and Fexofenadine in Participants With Seasonal Allergic Rhinitis (P08712) Completed NCT01469234 Phase 4 loratadine;fexofenadine;placebo to loratadine;placebo to fexofenadine
50 Steroid Sparing Effect of Nasal Corticosteroid In Asthma And Rhinitis Completed NCT00903227 Phase 4 Fluticasone Evohaler pMDI;Placebo;Fluticasone Evohaler;Placebo intranasal spray;fluticasone propionate (Flixonase®)

Search NIH Clinical Center for Rhinitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: rhinitis

Genetic Tests for Rhinitis

Genetic tests related to Rhinitis:

# Genetic test Affiliating Genes
1 Rhinitis 29

Anatomical Context for Rhinitis

MalaCards organs/tissues related to Rhinitis:

41
Testes, Skin, T Cells, Eye, Pituitary, Lung, Neutrophil

Publications for Rhinitis

Articles related to Rhinitis:

(show top 50) (show all 3897)
# Title Authors Year
1
Obesity and adiposity indicators in asthma and allergic rhinitis in children. ( 30507714 )
2019
2
The protective role of Piper nigrum fruit extract in an ovalbumin-induced allergic rhinitis by targeting of NFκBp65 and STAT3 signalings. ( 30551446 )
2019
3
Histamine H1 receptor gene polymorphism acts as a biological indicator of the prediction of therapeutic efficacy in patients with allergic rhinitis in the Chinese Han population. ( 30168182 )
2019
4
Comparison of Long-term Efficacy of Subcutaneous Immunotherapy in Pediatric and Adult Patients With Allergic Rhinitis. ( 30479078 )
2019
5
Occupational rhinitis, asthma, and contact urticaria from IgE-mediated allergy to pork. ( 30474282 )
2019
6
Glucocorticoid-Induced Transcription Factor 1 (GLCCI1) Variant Impacts the Short-Term Response to Intranasal Corticosteroids in Chinese Han Patients with Seasonal Allergic Rhinitis. ( 29981236 )
2018
7
Local allergic rhinitis: Implications for management. ( 29900607 )
2018
8
Establishment of the Nasal Microbiota in the first 18 Months of Life - Correlation with Early Onset Rhinitis and Wheezing. ( 29452199 )
2018
9
SOCS3 Is Upregulated and Targeted by miR30a-5p in Allergic Rhinitis. ( 29471302 )
2018
10
Basophils from allergic rhinitis patients show allergen-specific upregulation of thymic stromal lymphopoietin receptor. ( 29413340 )
2018
11
Relationship Between Rhinitis, Asthma, and Eczema and the Presence of Sensitization in Young Swiss Adults. ( 29977657 )
2018
12
Induced pluripotent stem cell-derived mesenchymal stem cells activate quiescent T cells and elevate regulatory T cell response via NF-I_B in allergic rhinitis patients. ( 29921316 )
2018
13
A Randomized, Multicenter, Double-blind, Phase III Study to Evaluate the Efficacy on Allergic Rhinitis and Safety of a Combination Therapy of Montelukast and Levocetirizine in Patients With Asthma and Allergic Rhinitis. ( 29945738 )
2018
14
Reply to the letter to the author concerning: 'Does adenoid hypertrophy affect disease severity in children with allergic rhinitis?' ( 29423746 )
2018
15
Impact of acupuncture on antihistamine use in patients suffering seasonal allergic rhinitis: secondary analysis of results from a randomised controlled trial. ( 29440045 )
2018
16
Efficacy of indoor air purification in treating Artemisia (mugwort) pollen allergic rhinitis: study protocol for a randomised controlled trial. ( 29976165 )
2018
17
Effects of anti-allergic drugs on T cell-mediated nasal hyperresponsiveness in a murine model of allergic rhinitis. ( 29910099 )
2018
18
Gene and protein expression of <i>CXCR4</i> in adult and elderly patients with chronic rhinitis, pharyngitis or sinusitis undergoing thermal water nasal inhalations. ( 29497453 )
2018
19
Evaluation of carbopol as an adjuvant on the effectiveness of progressive atrophic rhinitis vaccine. ( 29909135 )
2018
20
The International Study of the Allergic Rhinitis Survey: outcomes from 4 geographical regions. ( 29423374 )
2018
21
Occupational allergic rhinitis and contact urticaria caused by Gum Arabic in a candy factory worker. ( 29446105 )
2018
22
Economic Burden of the Inadequate Management of Allergic Rhinitis and Urticaria in Asian Countries Based on the GAA^LEN Model. ( 29949833 )
2018
23
Allergic rhinitis management: what's next? ( 29406839 )
2018
24
Cold weather increases respiratory symptoms and functional disability especially among patients with asthma and allergic rhinitis. ( 29973669 )
2018
25
Comparison of Specific Immunoglobulin E with the Skin Prick Test in the Diagnosis of House Dust Mites and Cockroach Sensitization in Patients with Asthma and/or Allergic Rhinitis. ( 29950531 )
2018
26
Validation of the Children's Sleep Habits Questionnaire in a sample of Greek children with allergic rhinitis. ( 29338964 )
2018
27
Correlation between upper and lower airway inflammations in patients with combined allergic rhinitis and asthma syndrome: A comparison of patients initially presenting with allergic rhinitis and those initially presenting with asthma. ( 29434763 )
2018
28
Evaluation of allergic rhinitis with nasal symptoms and nasal mucociliary clearance in patients with fibromyalgia syndrome. ( 29889054 )
2018
29
Changes in basophil activation during immunotherapy with house dust mite and mugwort in patients with allergic rhinitis. ( 29423373 )
2018
30
Associations of TAP1 genetic polymorphisms with atopic diseases: asthma, rhinitis and dermatitis. ( 29416713 )
2018
31
The use of specific immunoglobulin E in nasal secretions for the diagnosis of allergic rhinitis. ( 29417583 )
2018
32
Surgical Management of Nonallergic Rhinitis. ( 29937065 )
2018
33
Radiological comparison of inferior turbinate hypertrophy between allergic and non-allergic rhinitis: does allergy really augment turbinate hypertrophy? ( 29417277 )
2018
34
Distinct Gene Expression Patterns between Nasal Mucosal Cells and Blood Collected from Allergic Rhinitis Sufferers. ( 29920501 )
2018
35
Long-term efficacy of standardised specific subcutaneous immunotherapy in children with persistent allergic rhinitis due to multiple allergens including house dust mites. ( 29374499 )
2018
36
Onset of action for loratadine tablets for the symptomatic control of seasonal allergic rhinitis in adults challenged with ragweed pollen in the Environmental Exposure Unit: a post hoc analysis of total symptom score. ( 29371864 )
2018
37
The asthma-rhinitis multimorbidity is associated with IgE polysensitization in adolescents and adults. ( 29331026 )
2018
38
International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis. ( 29438602 )
2018
39
Otolaryngologist adherence to the AAO-HNSF Allergic Rhinitis Clinical Practice Guideline. ( 29412510 )
2018
40
Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis. ( 29949830 )
2018
41
Use of the Control of Allergic Rhinitis and Asthma Test and pulmonary function tests to assess asthma control in pregnancy. ( 28749014 )
2018
42
Repeatability of nasal allergen challenge results - further validation of the allergic rhinitis clinical investigator collaborative (AR-CIC) protocols. ( 29432965 )
2018
43
Pattern of allergic rhinitis among children in Ekiti, Nigeria. ( 29447897 )
2018
44
Cypress pollen allergy is responsible for two distinct phenotypes of allergic rhinitis different from other pollinosis. ( 29350019 )
2018
45
Effects of H1 antihistamine addition to intranasal corticosteroid for allergic rhinitis: a systematic review and meta-analysis. ( 29917324 )
2018
46
Isolation and profiling of plasma microRNAs: Biomarkers for Asthma and Allergic Rhinitis. ( 29906503 )
2018
47
From rhinitis to asthma: Is small airway disfunction the clue? ( 29914634 )
2018
48
International consensus statement on allergy and rhinology: allergic rhinitis-executive summary. ( 29438600 )
2018
49
Responsiveness of Nasal Provocation Testing-But Not Skin Test and Specific Immunoglobulin E Blood Level-Correlates With Severity of Allergic Rhinitis in Dermatophagoides Species-Sensitized Patients. ( 29909644 )
2018
50
Accuracy of serum-specific IgE test with microfluidic array enzyme-linked immunosorbent assay for diagnosing inhalant allergen sensitization in asthma and/or rhinitis allergy patients in Jakarta, Indonesia. ( 29423377 )
2018

Variations for Rhinitis

Expression for Rhinitis

Search GEO for disease gene expression data for Rhinitis.

Pathways for Rhinitis

Pathways related to Rhinitis according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.95 CCL11 CCL5 CXCL8 EPX ICAM1 IGHE
2
Show member pathways
13.63 CCL11 CCL5 CXCL8 IL13 IL4 IL4R
3
Show member pathways
13.5 CCL11 CCL5 CXCL8 ICAM1 IL13 IL4
4
Show member pathways
13.36 CCL11 CCL5 CXCL8 IL13 IL4 IL4R
5
Show member pathways
13.28 CCL11 CCL5 CXCL8 ICAM1 IGHE IL13
6
Show member pathways
13.24 CCL11 CCL5 CXCL8 IL13 IL4 IL4R
7 12.78 CXCL8 IL13 IL4 IL4R IL5
8
Show member pathways
12.76 CCL11 CXCL8 EPX ICAM1 IL13 IL4
9
Show member pathways
12.74 CCL5 CXCL8 ICAM1 IL13 IL4
10
Show member pathways
12.35 IL13 IL4 IL4R IL5
11
Show member pathways
12.34 CCL11 HRH1 IGHE IL4 IL4R
12
Show member pathways
12.29 CCL11 CCL5 CXCL8 ICAM1
13
Show member pathways
12.27 CCL11 CXCL8 IL13 IL4 IL5
14
Show member pathways
12.22 CXCL8 IL13 IL4 IL5 NGF
15
Show member pathways
12.17 CCL11 CCL5 CXCL8 ICAM1 VCAM1
16 12.14 CXCL8 IL13 NGF NR3C1
17 11.9 CCL5 ICAM1 VCAM1
18 11.85 CXCL8 ICAM1 VCAM1
19 11.83 IL4 IL4R IL5
20 11.82 CXCL8 ICAM1 VCAM1
21
Show member pathways
11.82 CCL11 CCL5 CXCL8 ICAM1 IL13 IL4
22 11.79 CCL5 CXCL8 ICAM1
23 11.73 IL13 IL4 IL5
24
Show member pathways
11.7 CXCL8 IL4 IL5
25 11.68 CCL11 CCL5 IL13 IL4
26 11.65 CCL11 IGHE IL4 IL4R IL5
27
Show member pathways
11.61 CXCL8 ICAM1 NR3C1 VCAM1
28 11.53 CCL11 CCL5 CXCL8 IL13 IL4 IL5
29 11.5 CXCL8 ICAM1 VCAM1
30 11.49 CCL5 CXCL8 ICAM1 IL13 IL4
31 11.44 CXCL8 ICAM1 VCAM1
32 11.41 CXCL8 ICAM1 IL13 IL4 IL5 NR3C1
33 11.38 CCL11 IL13 IL4 IL4R IL5
34 11.33 CCL11 CXCL8 ICAM1 IGHE IL13 IL4
35 11.29 IL4 IL4R IL5
36 11.27 IL13 IL4 IL5
37 11.22 IL13 IL4 IL5
38 11.18 CCL11 CCL5 CXCL8 IL13 IL4 IL5
39 11.16 IL13 IL4 IL5
40 10.94 CCL11 CCL5 CXCL8 IL13 IL4 IL5
41 10.92 CXCL8 POMC
42 10.89 ICAM1 VCAM1