MCID: RGH001
MIFTS: 48

Right Bundle Branch Block

Categories: Cardiovascular diseases

Aliases & Classifications for Right Bundle Branch Block

MalaCards integrated aliases for Right Bundle Branch Block:

Name: Right Bundle Branch Block 12 29 55 6 15 72
Right Bundle Branch Block with Left Posterior Fascicular Block 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13209
ICD9CM 35 426.51
SNOMED-CT 68 46319007
UMLS 72 C0085615 C0155704

Summaries for Right Bundle Branch Block

MalaCards based summary : Right Bundle Branch Block, also known as right bundle branch block with left posterior fascicular block, is related to ventricular fibrillation, paroxysmal familial, 1 and brugada syndrome 2. An important gene associated with Right Bundle Branch Block is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5), and among its related pathways/superpathways are Activation of cAMP-Dependent PKA and Developmental Biology. The drugs Carvedilol and Enalapril have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and lung, and related phenotype is cardiovascular system.

Wikipedia : 75 A right bundle branch block (RBBB) is a heart block in the right bundle branch of the electrical... more...

Related Diseases for Right Bundle Branch Block

Diseases related to Right Bundle Branch Block via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 133)
# Related Disease Score Top Affiliating Genes
1 ventricular fibrillation, paroxysmal familial, 1 33.2 SCN5A CACNA1C
2 brugada syndrome 2 33.0 SCN5A GPD1L
3 brugada syndrome 5 32.7 SCN5A SCN1B
4 atrioventricular block 31.5 TRPM4 SCN5A HCN4
5 first-degree atrioventricular block 30.6 SCN5A DSG4
6 sick sinus syndrome 30.5 SCN5A HCN4 CACNA1C
7 sinoatrial node disease 30.5 SCN5A HCN4
8 familial progressive cardiac conduction defect 30.3 TRPM4 SCN5A SCN1B
9 third-degree atrioventricular block 30.0 SCN5A HCN4 DSG4
10 cardiac arrhythmia 29.9 SCN5A CACNA1C
11 heart disease 29.5 SCN5A HCN4 CACNA1C BMPR2
12 brugada syndrome 29.2 TRPM4 SCN5A SCN3B SCN2B SCN1B KCND3
13 atrial fibrillation 29.0 SCN5A SCN3B SCN2B SCN1B HCN4
14 long qt syndrome 27.8 TRPM4 SCN5A SCN1B KCND3 HCN4 GPD1L
15 progressive familial heart block, type ib 12.6
16 brugada syndrome 1 12.4
17 progressive familial heart block, type ia 12.3
18 brugada syndrome 3 11.5
19 brugada syndrome 4 11.5
20 brugada syndrome 6 11.5
21 brugada syndrome 7 11.5
22 brugada syndrome 8 11.5
23 brugada syndrome 9 11.5
24 left bundle branch hemiblock 10.9
25 acute myocardial infarction 10.8
26 heart septal defect 10.8
27 tetralogy of fallot 10.7
28 ventricular septal defect 10.7
29 myocardial infarction 10.7
30 cardiac conduction defect 10.7
31 syncope 10.7
32 atrial standstill 1 10.6
33 wolff-parkinson-white syndrome 10.6
34 congestive heart failure 10.6
35 atrial heart septal defect 10.5
36 ischemia 10.5
37 arrhythmogenic right ventricular cardiomyopathy 10.5
38 coronary heart disease 1 10.5
39 anteroseptal myocardial infarction 10.5
40 pulmonary embolism 10.5
41 atrioventricular dissociation 10.4
42 hyperlipoproteinemia, type iii 10.4
43 cardiac arrest 10.4
44 coronary artery anomaly 10.4
45 second-degree atrioventricular block 10.4
46 inferior myocardial infarction 10.4
47 hypertrophic cardiomyopathy 10.4
48 cardiogenic shock 10.4
49 familial sick sinus syndrome 10.4 SCN5A HCN4
50 chagas disease 10.3

Comorbidity relations with Right Bundle Branch Block via Phenotypic Disease Network (PDN): (show all 27)


Acute Cystitis Aortic Valve Disease 1
Atrioventricular Block Benign Essential Hypertension
Bronchitis Chronic Pulmonary Heart Disease
Deficiency Anemia Esophagitis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Intermediate Coronary Syndrome
Left Bundle Branch Hemiblock Mitral Valve Disease
Mobitz Type Ii Atrioventricular Block Peripheral Vascular Disease
Postinflammatory Pulmonary Fibrosis Progressive Familial Heart Block, Type Ia
Prostatic Hypertrophy Pulmonary Hypertension, Primary, 1
Respiratory Failure Sinoatrial Node Disease
Third-Degree Atrioventricular Block Transient Cerebral Ischemia
Tricuspid Valve Disease

Graphical network of the top 20 diseases related to Right Bundle Branch Block:



Diseases related to Right Bundle Branch Block

Symptoms & Phenotypes for Right Bundle Branch Block

MGI Mouse Phenotypes related to Right Bundle Branch Block:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.23 BMPR2 CACNA1C CACNB2 HCN4 KCND3 SCN3B

Drugs & Therapeutics for Right Bundle Branch Block

Drugs for Right Bundle Branch Block (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carvedilol Approved, Investigational Phase 4 72956-09-3 2585
2
Enalapril Approved, Vet_approved Phase 4 75847-73-3 5362032 40466924
3
Enalaprilat Approved Phase 4 76420-72-9 6917719
4
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
5 Neurotransmitter Agents Phase 4
6 Antihypertensive Agents Phase 4
7 Natriuretic Peptide, Brain Phase 4
8 Hormones Phase 4
9 Antioxidants Phase 4
10 Adrenergic alpha-Antagonists Phase 4
11 HIV Protease Inhibitors Phase 4
12 Adrenergic beta-Antagonists Phase 4
13
protease inhibitors Phase 4
14 Adrenergic alpha-1 Receptor Antagonists Phase 4
15 Angiotensin-Converting Enzyme Inhibitors Phase 4
16 Adrenergic Agents Phase 4
17 Adrenergic Antagonists Phase 4
18 Protective Agents Phase 4
19 Vasodilator Agents Phase 4
20 calcium channel blockers Phase 4
21 Calcium, Dietary Phase 4
22 Bronchodilator Agents

Interventional clinical trials:

(show all 19)
# Name Status NCT ID Phase Drugs
1 A Randomized Trial of Carvedilol After Renin-angiotensin System Inhibition in Chronic Chagas Cardiomyopathy Completed NCT01557140 Phase 4 RASi plus carvedilol
2 Prevention of Early Readmission in Elderly Congestive Heart Failure Patients Completed NCT00000475 Phase 2
3 Congenital or Idiopathic Complete Right Bundle Branch Block: Physiological Significance and Molecular Characterization Unknown status NCT00173342
4 Clinical Profile of Patients With Pulmonary Hypertension Due to Lung Diseases ( Single Center Experience) Unknown status NCT02774928
5 Postoperative Right Bundle Branch Block - Long-term Effect on the Right Ventricle in Children Operated for Ventricular Septal Defect Completed NCT01480908
6 Prevalence of Chagas Disease in Immigrant Patients With Conduction Abnormalities on Electrocardiogram Completed NCT00453700
7 SL-AF Trial - (Six Lead Identification of Atrial Fibrillation [AF]) Completed NCT02401451
8 Risk of Cardiovascular Disease in Soccer Referees: a Cross Sectional Study Completed NCT03171285
9 Novel Methods for Arrhythmia Detection: Chest Strap ECG and Wrist Band Photoplethysmography Compared to Holter-device for Atrial Fibrillation Detection Completed NCT03721601
10 Predicting Hypoglycaemia and Arrhythmias in the Vulnerable Patient With Diabetes and Chronic Kidney Disease Completed NCT02315300
11 Biventricular Pacing in Children After Surgery for Congenital Heart Disease Completed NCT02806245
12 Predicting Hypoglycaemia and Arrhythmias in the Vulnerable Patient With Diabetes and Chronic Kidney Disease - Validation Study Completed NCT02778269
13 Right Ventricular Septal Pacing in Patients With Right Bundle Branch Block and Heart Failure, a Pilot Clinical Trial (The SPARK Trial) Recruiting NCT02441101
14 Ventricular Electrical Synchronization by Stimulating Left and Right Bundle Branches Area in Pacing-indicated Patients Recruiting NCT04023890
15 Permanent Left Bundle Branch Area Pacing for Atrioventricular Block Recruiting NCT03851315
16 Bifocal Right Ventricular PAcing in Right Bundle Branch blocK and Heart Failure With Reduced Ejection Fraction Recruiting NCT03524001
17 Chest Strap and PPG-device Compared to Holter-device for Atrial Fibrillation Detection: 24 Hour Study Recruiting NCT03507335
18 Imaging of Ventricular Reversed Remodeling After Double Lung Transplantation in Patients With Pulmonary Arterial Hypertension Enrolling by invitation NCT02391441
19 Pacing Affects Cardiovascular Endpoints in Patients With Right Bundle-Branch Block (The PACE-RBBB Trial) Terminated NCT01169493

Search NIH Clinical Center for Right Bundle Branch Block

Genetic Tests for Right Bundle Branch Block

Genetic tests related to Right Bundle Branch Block:

# Genetic test Affiliating Genes
1 Right Bundle Branch Block 29

Anatomical Context for Right Bundle Branch Block

MalaCards organs/tissues related to Right Bundle Branch Block:

41
Heart, Testes, Lung, Kidney, Brain, Atrioventricular Node, Spinal Cord

Publications for Right Bundle Branch Block

Articles related to Right Bundle Branch Block:

(show top 50) (show all 3255)
# Title Authors PMID Year
1
Brugada disease: chronology of discovery and paternity. Preliminary observations and historical aspects. 9 38
16943925 2003
2
A novel SCN5A mutation associated with idiopathic ventricular fibrillation without typical ECG findings of Brugada syndrome. 9 38
10940383 2000
3
Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts. 9 38
10662748 2000
4
ECG clues for false ST-segment elevation myocardial infarction activations. 38
30694822 2019
5
J-Wave Elevation in the Inferior Leads Predicts Lethal Ventricular Arrhythmia Initiated by Premature Ventricular Contractions With Right Bundle Branch Block and Superior Axis. 38
31391386 2019
6
Trastuzumab-Induced Cardiomyopathy and Intermittent Left Bundle Branch Block. 38
31413780 2019
7
Conduction Abnormalities and Long-Term Mortality Following Septal Myectomy in Patients With Obstructive Hypertrophic Cardiomyopathy. 38
31370956 2019
8
Clinical implications of electrocardiographic bundle branch block in primary care. 38
31129608 2019
9
Heartbeat: pacer risk in patients with right bundle branch block. 38
31308094 2019
10
Isolated right bundle branch block in asymptomatic patients: not inconsequential as previously thought? 38
31129610 2019
11
Electrical parameters with His bundle pacing: considerations for automated programming. 38
31377421 2019
12
Ischemic ventricular tachycardia from below the posteromedial papillary muscle, a particular entity: Substrate characterization and challenges for catheter ablation. 38
31085181 2019
13
Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function. 38
31366290 2019
14
Right bundle branch block: Prevalence, incidence, and cardiovascular morbidity and mortality in the general population. 38
31339387 2019
15
Prenatal diagnosis of a bundle branch block based on the fetal ECG. 38
31266761 2019
16
Transient high-degree right bundle branch block masking the type 1 Brugada ECG pattern associated with possible transient early repolarization syndrome. 38
31343106 2019
17
Cardiac conduction abnormalities associated with pacemaker implantation after transcatheter aortic valve replacement. 38
30977144 2019
18
Interesting case of narrow QRS tachycardia. What is the mechanism? 38
31037743 2019
19
The characteristics of the electrocardiogram and the intracardiac electrogram in left bundle branch pacing. 38
31094058 2019
20
Prognostic Implication of Ventricular Conduction Disturbance Pattern in Hospitalized Patients with Acute Heart Failure Syndrome. 38
30891964 2019
21
A case of elusive cardiac dysrhythmia in high-risk syncope. 38
31387810 2019
22
Predicting the outcome of acute pulmonary embolism by dynamic changes of the QRS complex in lead V1. 38
31203174 2019
23
Transient left anterior and septal fascicular blocks after self-expandable percutaneous transcatheter aortic valve implantation. 38
29675905 2019
24
Electrocardiographic and Electrophysiologic Characteristics of Idiopathic Ventricular Arrhythmias Originating From the Basal Inferoseptal Left Ventricle. 38
31320012 2019
25
HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure. 38
31286141 2019
26
Effect of Left Ventricular Conduction Delay on All-Cause and Cardiovascular Mortality (from the PRECISION Trial). 38
31395295 2019
27
Cardiac Resynchronization Defibrillator Therapy for Nonspecific Intraventricular Conduction Delay Versus Right Bundle Branch Block. 38
31221257 2019
28
Complete atrioventricular block caused by pulmonary embolism: A case report and review of literature. 38
31248624 2019
29
Use of Cardiac Resynchronization Therapy Defibrillator in US Hospitals. 38
31215970 2019
30
ECG anomaly class identification using LSTM and error profile modeling. 38
31030180 2019
31
Late Cardiac Complications of Sulfur Mustard Poisoning in 38 Iranian Veterans. 38
30242562 2019
32
Congenital myopathies are mainly associated with a mild cardiac phenotype. 38
30874888 2019
33
Pacemaker Dependency after Transcatheter Aortic Valve Implantation: Incidence, Predictors and Long-term outcomes. 38
31217147 2019
34
Outcomes of Acute Conduction Abnormalities Following Transcatheter Aortic Valve Implantation With a Balloon Expandable Valve and Predictors of Delayed Conduction System Abnormalities in Follow-up. 38
30922540 2019
35
Prognostic Value of Electrocardiography in Elderly Patients with Acute Pulmonary Embolism. 38
31247179 2019
36
Association of Newly Developed Right Bundle Branch Block with Graft Rejection Following Heart Transplantation. 38
31016903 2019
37
Interference dissociation during a baseline complete left bundle-branch block with advanced right bundle-branch block. 38
30974222 2019
38
Diagnosis of right bundle branch block: a concordance study. 38
31060516 2019
39
New ECG criteria for differential diagnosis of wide QRS complex tachycardias with right bundle branch block pattern. 38
31094481 2019
40
Impact of the repositionable Evolut R CoreValve system on the need for a permanent pacemaker after transcatheter aortic valve implantation in patients with severe aortic stenosis. 38
31062927 2019
41
Ambulatory Rhythm Monitoring to Detect Late High-Grade Atrioventricular Block Following Transcatheter Aortic Valve Replacement. 38
31118148 2019
42
Prospective evaluation of feasibility, electrophysiologic and echocardiographic characteristics of left bundle branch area pacing. 38
31136869 2019
43
Electrocardiographic changes in spondyloarthritis and use of anti-TNF-α drugs: a retrospective study with 100 patients. 38
30942280 2019
44
Intracardiac Delineation of Septal Conduction in Left Bundle-Branch Block Patterns. 38
30704273 2019
45
Ablation of ventricular arrhythmias with predominant monophasic "R" waves in precordial leads from the left sinus of Valsalva: Electrocardiographic and electrophysiologic characteristics. 38
30661263 2019
46
Transcatheter aortic valve replacement and cardiac conduction. 38
30912984 2019
47
New postoperative conduction abnormalities after the implantation of a rapid-deployment aortic valve prosthesis. 38
30412244 2019
48
Permanent left bundle branch area pacing for atrioventricular block: Feasibility, safety, and acute effect. 38
31048065 2019
49
Integration of cardiac magnetic resonance imaging, electrocardiographic imaging, and coronary venous computed tomography angiography for guidance of left ventricular lead positioning. 38
30590434 2019
50
Unique electrocardiographic pattern "w" wave in lead I of idiopathic ventricular arrhythmias arising from the distal great cardiac vein. 38
30987582 2019

Variations for Right Bundle Branch Block

ClinVar genetic disease variations for Right Bundle Branch Block:

6
# Gene Variation Type Significance SNP ID GRCh37 Pos GRCh38 Pos
1 BMPR2 NM_001204.7(BMPR2): c.2948G> A (p.Arg983Gln) single nucleotide variant Likely benign rs148099152 2:203424500-203424500 2:202559777-202559777

Expression for Right Bundle Branch Block

Search GEO for disease gene expression data for Right Bundle Branch Block.

Pathways for Right Bundle Branch Block

Pathways related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.23 SCN5A SCN3B SCN2B SCN1B CACNB2 CACNA1C
2
Show member pathways
13.19 SCN5A SCN3B SCN2B SCN1B DSG4 CACNB2
3
Show member pathways
12.71 SCN5A SCN3B SCN2B SCN1B CACNB2 CACNA1C
4
Show member pathways
12.57 TRPM4 SCN5A SCN1B CACNB2 CACNA1C
5
Show member pathways
12.53 SCN5A SCN3B SCN2B SCN1B KCND3 CACNB2
6
Show member pathways
12.35 SCN5A SCN3B SCN2B SCN1B
7 12.06 KCND3 CACNB2 CACNA1C
8 11.86 SCN5A SCN3B GPD1L
9
Show member pathways
11.72 SCN5A SCN3B SCN2B SCN1B
10
Show member pathways
11.31 SCN5A SCN3B SCN2B SCN1B CACNB2 CACNA1C
11 11.23 CACNB2 CACNA1C
12 11.08 CACNB2 CACNA1C
13 10.97 SCN5A SCN3B SCN2B SCN1B KCND3 HCN4
14 10.93 SCN5A SCN3B SCN2B SCN1B

GO Terms for Right Bundle Branch Block

Cellular components related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.9 TRPM4 SCN5A SCN3B SCN1B KCND3 HCN4
2 Z disc GO:0030018 9.63 SCN5A SCN3B CACNA1C
3 intercalated disc GO:0014704 9.51 SCN5A SCN1B
4 T-tubule GO:0030315 9.49 SCN5A SCN1B
5 voltage-gated calcium channel complex GO:0005891 9.48 CACNB2 CACNA1C
6 L-type voltage-gated calcium channel complex GO:1990454 9.43 CACNB2 CACNA1C
7 sodium channel complex GO:0034706 9.37 TRPM4 SCN1B
8 spanning component of plasma membrane GO:0044214 9.32 TRPM4 BMPR2
9 sarcolemma GO:0042383 9.26 SCN5A KCND3 CACNB2 CACNA1C
10 voltage-gated sodium channel complex GO:0001518 8.92 SCN5A SCN3B SCN2B SCN1B
11 integral component of membrane GO:0016021 10.1 TRPM4 SCN5A SCN3B SCN2B SCN1B KCND3
12 membrane GO:0016020 10.03 TRPM4 SCN5A SCN3B SCN2B SCN1B KCND3

Biological processes related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

(show all 34)
# Name GO ID Score Top Affiliating Genes
1 sodium ion transport GO:0006814 9.95 SCN5A SCN3B SCN2B SCN1B HCN4
2 sodium ion transmembrane transport GO:0035725 9.88 SCN5A SCN3B SCN2B SCN1B HCN4
3 cardiac muscle contraction GO:0060048 9.86 SCN5A SCN3B SCN2B SCN1B
4 calcium ion transport GO:0006816 9.82 TRPM4 CACNB2 CACNA1C
5 calcium ion transmembrane transport GO:0070588 9.82 TRPM4 CACNB2 CACNA1C
6 regulation of sodium ion transmembrane transporter activity GO:2000649 9.8 SCN3B SCN2B SCN1B GPD1L
7 regulation of heart rate GO:0002027 9.77 SCN5A HCN4 GPD1L
8 membrane depolarization GO:0051899 9.76 SCN5A SCN3B SCN1B
9 positive regulation of sodium ion transport GO:0010765 9.76 SCN5A SCN3B SCN1B GPD1L
10 regulation of ion transmembrane transport GO:0034765 9.76 SCN5A SCN3B SCN2B SCN1B KCND3 HCN4
11 ventricular cardiac muscle cell action potential GO:0086005 9.75 SCN5A SCN3B GPD1L
12 regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 9.74 SCN5A SCN3B GPD1L
13 cardiac conduction GO:0061337 9.73 TRPM4 SCN3B SCN1B CACNA1C
14 SA node cell action potential GO:0086015 9.71 SCN5A SCN3B HCN4
15 regulation of atrial cardiac muscle cell membrane depolarization GO:0060371 9.71 SCN5A SCN3B SCN2B SCN1B
16 membrane depolarization during Purkinje myocyte cell action potential GO:0086047 9.7 TRPM4 SCN5A SCN1B
17 membrane depolarization during atrial cardiac muscle cell action potential GO:0098912 9.69 SCN5A CACNB2 CACNA1C
18 chemical synaptic transmission GO:0007268 9.66 SCN2B CACNB2
19 calcium ion import GO:0070509 9.66 CACNB2 CACNA1C
20 regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 9.65 SCN5A SCN1B
21 positive regulation of heart rate GO:0010460 9.65 TRPM4 SCN3B
22 cardiac muscle cell action potential involved in contraction GO:0086002 9.65 SCN5A SCN3B SCN2B SCN1B CACNA1C
23 membrane depolarization during action potential GO:0086010 9.64 SCN5A SCN3B
24 sodium ion import across plasma membrane GO:0098719 9.63 TRPM4 HCN4
25 regulation of ventricular cardiac muscle cell action potential GO:0098911 9.63 TRPM4 CACNA1C
26 atrial cardiac muscle cell action potential GO:0086014 9.62 SCN5A SCN3B
27 membrane depolarization during AV node cell action potential GO:0086045 9.62 TRPM4 SCN5A CACNB2 CACNA1C
28 membrane depolarization during SA node cell action potential GO:0086046 9.61 SCN5A HCN4
29 response to pyrethroid GO:0046684 9.61 SCN2B SCN1B
30 membrane depolarization during bundle of His cell action potential GO:0086048 9.6 TRPM4 SCN5A
31 membrane depolarization during cardiac muscle cell action potential GO:0086012 9.43 SCN5A SCN3B SCN2B SCN1B HCN4 CACNA1C
32 regulation of heart rate by cardiac conduction GO:0086091 9.28 TRPM4 SCN5A SCN3B SCN2B SCN1B KCND3
33 transmembrane transport GO:0055085 10.02 TRPM4 SCN5A KCND3 HCN4 CACNA1C
34 ion transport GO:0006811 10.02 TRPM4 SCN5A SCN3B SCN2B SCN1B KCND3

Molecular functions related to Right Bundle Branch Block according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 ion channel binding GO:0044325 9.77 SCN5A SCN3B SCN1B KCND3 GPD1L
2 ion channel activity GO:0005216 9.73 TRPM4 SCN5A HCN4 CACNA1C
3 calmodulin binding GO:0005516 9.71 TRPM4 SCN5A CACNA1C
4 calcium channel activity GO:0005262 9.7 TRPM4 CACNB2 CACNA1C
5 sodium channel regulator activity GO:0017080 9.62 SCN3B SCN2B SCN1B GPD1L
6 voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0086006 9.56 SCN5A SCN3B SCN2B SCN1B
7 voltage-gated calcium channel activity GO:0005245 9.55 CACNB2 CACNA1C
8 voltage-gated sodium channel activity GO:0005248 9.55 SCN5A SCN3B SCN2B SCN1B HCN4
9 high voltage-gated calcium channel activity GO:0008331 9.51 CACNB2 CACNA1C
10 voltage-gated ion channel activity GO:0005244 9.5 SCN5A SCN3B SCN2B SCN1B KCND3 HCN4
11 sodium channel inhibitor activity GO:0019871 9.49 SCN3B SCN1B
12 voltage-gated calcium channel activity involved in cardiac muscle cell action potential GO:0086007 9.48 CACNB2 CACNA1C
13 voltage-gated calcium channel activity involved in AV node cell action potential GO:0086056 9.46 CACNB2 CACNA1C
14 voltage-gated sodium channel activity involved in Purkinje myocyte action potential GO:0086062 9.4 SCN5A SCN1B
15 sodium channel activity GO:0005272 9.02 SCN5A SCN3B SCN2B SCN1B HCN4

Sources for Right Bundle Branch Block

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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