Rocky Mountain Spotted Fever (RMSF)

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Orphanet: ⁵⁸ A rare, acquired, life-threatening, infectious disease due to the tick-borne bacteria Rickettsia rickettsii characterized by an acute onset of fever, malaise, and severe headache, variably accompanied by myalgia, anorexia, nausea, vomiting, abdominal pain, and photophobia, associating (2-5 days after fever onset) a typically erythematous, blanching or non-blanching, maculopapluar rash with petechiae, starting on the wrists and ankles and progressing centrifugally to the palms and soles and centripetally to the arms, legs and trunk. Additonal variable features may include conjunctivitis, mucosal ulcers, post-inflammatory hyperpigmentation, jaundice, pneumonia, hepatomegaly, renal failure, meningismus, amnesia, optic disc edema, and ocular arterial occlusion.

MalaCards based summary: Rocky Mountain Spotted Fever, also known as exanthematic typhus of sao paulo, is related to queensland tick typhus and israeli tick typhus, and has symptoms including fever, abdominal pain and headache. An important gene associated with Rocky Mountain Spotted Fever is SLC17A5 (Solute Carrier Family 17 Member 5). The drugs Azithromycin and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include endothelial, salivary gland and skin.

GARD: ¹⁹ Rocky mountain spotted fever refers to an infection caused by the bacterium Rickettsia rickettsia. This particular bacterium is carried by certain species of ticks and spread to humans through the bites of infected ticks. Signs and symptoms of the condition generally develop approximately 2 to 14 days following the tick bite and may include fever, rash, headache, muscle pain, chills, and/or confusion. Some affected people may also experience diarrhea, nausea, vomiting, light sensitivity, hallucinations, and/or excessive thirst. Most cases occur in the spring and summer and are found in children. Risk factors for developing the condition include recent hiking or exposure to ticks in an area where the disease is known to occur.

Disease Ontology: ¹¹ A spotted fever that has material basis in Rickettsia rickettsii, which is transmitted by ticks (Dermacentor variabilis and Dermacentor andersoni). The infection has symptom fever, has symptom headache, has symptom abdominal pain, and has symptom maculopapular rash progressing into papular or petechial rash.

CDC: ² Rocky Mountain spotted fever (RMSF) is a bacterial disease spread through the bite of an infected tick. Most people who get sick with RMSF will have a fever, headache, and rash. RMSF can be deadly if not treated early with the right antibiotic.

Wikipedia: ⁷⁵ Rocky Mountain spotted fever (RMSF) is a bacterial disease spread by ticks. It typically begins with a... more...

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