Aliases & Classifications for Ross River Fever

MalaCards integrated aliases for Ross River Fever:

Name: Ross River Fever 12 15 73
Ross River Virus Infection 73
Ross River Virus Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050518
ICD10 33 B33.1

Summaries for Ross River Fever

Disease Ontology : 12 A viral infectious disease that results in infection located in joint, has material basis in Ross River virus, which is transmitted by Culex, and transmitted by Aedes mosquitoes. The infection has symptom fever, has symptom arthralgia, and has symptom rash.

MalaCards based summary : Ross River Fever, also known as ross river virus infection, is related to q fever and immunoglobulin a deficiency 1, and has symptoms including fever, arthralgia and rash. An important gene associated with Ross River Fever is CD40LG (CD40 Ligand), and among its related pathways/superpathways are Toxoplasmosis and IL4-mediated signaling events. The drugs Aluminum hydroxide and Formaldehyde have been mentioned in the context of this disorder. Affiliated tissues include joint, and related phenotypes are cardiovascular system and immune system

Wikipedia : 76 Ross River fever is a mosquito-borne infectious disease caused by infection with the Ross River virus.... more...

Related Diseases for Ross River Fever

Diseases related to Ross River Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Related Disease Score Top Affiliating Genes
1 q fever 30.2 CD40LG IL10
2 immunoglobulin a deficiency 1 10.1 CD40LG IL10
3 sporotrichosis 10.1 CD40LG IL10
4 necrotizing ulcerative gingivitis 10.1 CD40LG IL10
5 buruli ulcer 10.1 CD40LG IL10
6 primary systemic mycosis 10.1 CD40LG IL10
7 cystic echinococcosis 10.1 CD40LG IL10
8 coccidiosis 10.1 CD40LG IL10
9 hemorrhagic fever 10.1 CD40LG IL10
10 mycetoma 10.1 COMT IL10
11 traumatic brain injury 10.1 COMT IL10
12 panuveitis 10.1 CD40LG IL10
13 scrub typhus 10.1 CD40LG IL10
14 plasmodium vivax malaria 10.1 CD40LG IL10
15 churg-strauss syndrome 10.1 CD40LG IL10
16 hemorrhagic fever with renal syndrome 10.1 CD40LG IL10
17 extrinsic cardiomyopathy 10.1 CD40LG IL10
18 idiopathic neutropenia 10.1 CD40LG IL10
19 opportunistic mycosis 10.1 CD40LG IL10
20 brain injury 10.1 COMT IL10
21 mixed connective tissue disease 10.1 CD40LG IL10
22 echinococcosis 10.1 CD40LG IL10
23 leptospirosis 10.1 CD40LG IL10
24 secondary progressive multiple sclerosis 10.1 CD40LG IL10
25 brucellosis 10.1 CD40LG IL10
26 parasitic helminthiasis infectious disease 10.1 CD40LG IL10
27 upper respiratory tract disease 10.1 CD40LG IL10
28 primary sjögren syndrome 10.1 CD40LG IL10
29 dengue hemorrhagic fever 10.1 CD40LG IL10
30 human immunodeficiency virus infectious disease 10.1 CD40LG IL10
31 leprosy 3 10.0 CD40LG IL10
32 parasitic protozoa infectious disease 10.0 CD40LG IL10
33 rubella 10.0 CD40LG IL10
34 primary bacterial infectious disease 10.0 CD40LG IL10
35 toxoplasmosis 10.0 CD40LG IL10
36 chlamydia 10.0 CD40LG IL10
37 hypersensitivity reaction disease 10.0 CD40LG IL10
38 schistosomiasis 10.0 CD40LG IL10
39 chronic fatigue syndrome 10.0 COMT IL10
40 respiratory system disease 10.0 CD40LG IL10
41 bronchiolitis 10.0 CD40LG IL10
42 otitis media 10.0 CD40LG IL10
43 rheumatic disease 10.0 CD40LG IL10
44 acquired immunodeficiency syndrome 9.9 CD40LG IL10
45 immune system disease 9.9 CD40LG IL10
46 meningitis 9.9 CD40LG IL10
47 transient arthritis 9.9 CD40LG COMP
48 tetanus 9.9 CD40LG IL10
49 gastrointestinal system disease 9.9 CD40LG IL10
50 demyelinating disease 9.9 CD40LG IL10

Graphical network of the top 20 diseases related to Ross River Fever:



Diseases related to Ross River Fever

Symptoms & Phenotypes for Ross River Fever

Symptoms:

12
  • fever
  • arthralgia
  • rash

MGI Mouse Phenotypes related to Ross River Fever:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.26 CD40LG COMP COMT IL10
2 immune system MP:0005387 8.92 CD40LG COMP COMT IL10

Drugs & Therapeutics for Ross River Fever

Drugs for Ross River Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aluminum hydroxide Approved, Investigational Phase 3,Phase 1,Phase 2 21645-51-2
2
Formaldehyde Approved, Vet_approved Phase 3,Phase 1,Phase 2 50-00-0 712
3 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
4 Antacids Phase 3,Phase 1,Phase 2
5 Anti-Ulcer Agents Phase 3,Phase 1,Phase 2
6 Gastrointestinal Agents Phase 3,Phase 1,Phase 2
7 Vaccines Phase 3,Phase 1,Phase 2
8 Anti-Infective Agents Phase 1, Phase 2
9 Disinfectants Phase 1, Phase 2
10
Albendazole Approved, Vet_approved Not Applicable 54965-21-8 2082
11
Ivermectin Approved, Investigational, Vet_approved Not Applicable 70288-86-7 6474909
12
Mebendazole Approved, Vet_approved Not Applicable 31431-39-7 4030

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Ross River Virus (RRV) Vaccine Study Completed NCT01242670 Phase 3
2 Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801 Completed NCT01604746 Phase 3
3 Safety and Immunogenicity Study of a Ross River Virus (RRV) Vaccine Completed NCT00717834 Phase 1, Phase 2
4 The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands Completed NCT01080989 Not Applicable

Search NIH Clinical Center for Ross River Fever

Genetic Tests for Ross River Fever

Anatomical Context for Ross River Fever

The Foundational Model of Anatomy Ontology organs/tissues related to Ross River Fever:

19
Joint

Publications for Ross River Fever

Articles related to Ross River Fever:

# Title Authors Year
1
Neurocognitive disturbances associated with acute infectious mononucleosis, Ross River fever and Q fever: A preliminary investigation of inflammatory and genetic correlates. ( 24211375 )
2014
2
Update on Ross River fever. ( 8280003 )
1993

Variations for Ross River Fever

Expression for Ross River Fever

Search GEO for disease gene expression data for Ross River Fever.

Pathways for Ross River Fever

Pathways related to Ross River Fever according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.53 CD40LG IL10
2 10.96 CD40LG IL10
3 10.68 CD40LG IL10
4 10.49 CD40LG COMP IL10

GO Terms for Ross River Fever

Biological processes related to Ross River Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.33 CD40LG COMP IL10
2 response to lipopolysaccharide GO:0032496 9.32 COMT IL10
3 B cell differentiation GO:0030183 9.26 CD40LG IL10
4 B cell proliferation GO:0042100 8.96 CD40LG IL10
5 regulation of sensory perception of pain GO:0051930 8.62 COMT IL10

Sources for Ross River Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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