Aliases & Classifications for Ross River Fever

MalaCards integrated aliases for Ross River Fever:

Name: Ross River Fever 12 15 73
Ross River Virus Infection 73
Ross River Virus Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050518
ICD10 33 B33.1

Summaries for Ross River Fever

Disease Ontology : 12 A viral infectious disease that results in infection located in joint, has material basis in Ross River virus, which is transmitted by Culex, and transmitted by Aedes mosquitoes. The infection has symptom fever, has symptom arthralgia, and has symptom rash.

MalaCards based summary : Ross River Fever, also known as ross river virus infection, is related to q fever and mycetoma, and has symptoms including fever, arthralgia and rash. An important gene associated with Ross River Fever is COMP (Cartilage Oligomeric Matrix Protein), and among its related pathways/superpathways is Malaria. The drugs Aluminum hydroxide and Formaldehyde have been mentioned in the context of this disorder. Affiliated tissues include joint, brain and bone, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 76 Ross River fever is a mosquito-borne infectious disease caused by infection with the Ross River virus.... more...

Related Diseases for Ross River Fever

Diseases related to Ross River Fever via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 q fever 10.1
2 mycetoma 9.9 COMT IL10
3 traumatic brain injury 9.8 COMT IL10
4 brain injury 9.8 COMT IL10
5 reactive arthritis 9.8 COMP IL10
6 bone inflammation disease 9.8 COMP IL10
7 chronic fatigue syndrome 9.8 COMT IL10
8 rheumatoid arthritis 9.6 COMP IL10

Graphical network of the top 20 diseases related to Ross River Fever:



Diseases related to Ross River Fever

Symptoms & Phenotypes for Ross River Fever

Symptoms:

12
  • fever
  • arthralgia
  • rash

GenomeRNAi Phenotypes related to Ross River Fever according to GeneCards Suite gene sharing:

26 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 9.4 IL10
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 9.4 IL10
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-211 9.4 COMT
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-26 9.4 COMT
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.4 COMT
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.4 IL10
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.4 COMT IL10
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.4 IL10
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.4 IL10
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.4 COMT
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.4 COMT

MGI Mouse Phenotypes related to Ross River Fever:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 8.8 COMP COMT IL10

Drugs & Therapeutics for Ross River Fever

Drugs for Ross River Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aluminum hydroxide Approved, Investigational Phase 3 21645-51-2
2
Formaldehyde Approved, Vet_approved Phase 3,Phase 1,Phase 2 50-00-0 712
3 Adjuvants, Immunologic Phase 3
4 Immunologic Factors Phase 3,Phase 1,Phase 2
5 Anti-Ulcer Agents Phase 3
6 Antacids Phase 3
7 Vaccines Phase 3,Phase 1,Phase 2
8 Gastrointestinal Agents Phase 3
9 Disinfectants Phase 1, Phase 2
10 Anti-Infective Agents Phase 1, Phase 2
11
Ivermectin Approved, Investigational, Vet_approved Not Applicable 70288-86-7 6474909
12
Albendazole Approved, Vet_approved Not Applicable 54965-21-8 2082
13
Mebendazole Approved, Vet_approved Not Applicable 31431-39-7 4030

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Ross River Virus (RRV) Vaccine Study Completed NCT01242670 Phase 3
2 Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801 Completed NCT01604746 Phase 3
3 Safety and Immunogenicity Study of a Ross River Virus (RRV) Vaccine Completed NCT00717834 Phase 1, Phase 2
4 The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands Completed NCT01080989 Not Applicable

Search NIH Clinical Center for Ross River Fever

Genetic Tests for Ross River Fever

Anatomical Context for Ross River Fever

The Foundational Model of Anatomy Ontology organs/tissues related to Ross River Fever:

19
Joint

MalaCards organs/tissues related to Ross River Fever:

41
Brain, Bone, Heart, T Cells

Publications for Ross River Fever

Articles related to Ross River Fever:

(show all 49)
# Title Authors Year
1
Mosquito and Virus Surveillance as a Predictor of Human Ross River Virus Infection in South-West Western Australia: How Useful Is It? ( 30182918 )
2018
2
Increased Proinflammatory Cytokine Levels in Prolonged Arthralgia in Ross River Virus Infection. ( 28322700 )
2017
3
Re-evaluating the residual risk of transfusion-transmitted Ross River virus infection. ( 26748600 )
2016
4
Ross River virus infection in a Thuringian traveller returning from south-east Australia. ( 25380568 )
2015
5
CD8+ T cells control Ross River virus infection in musculoskeletal tissues of infected mice. ( 25488988 )
2015
6
First reported case of transfusion-transmitted Ross River virus infection. ( 25758699 )
2015
7
Neurocognitive disturbances associated with acute infectious mononucleosis, Ross River fever and Q fever: A preliminary investigation of inflammatory and genetic correlates. ( 24211375 )
2014
8
Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection. ( 24429363 )
2014
9
Ross River virus infection surveillance in the Greater Perth Metropolitan area--has there been an increase in cases in the winter months? ( 25222206 )
2014
10
The seroprevalence and factors associated with Ross river virus infection in western grey kangaroos (Macropus fuliginosus) in Western Australia. ( 25325318 )
2014
11
Geographic Information Systems used to describe the link between the risk of Ross River virus infection and proximity to the Leschenault estuary, WA. ( 22672028 )
2012
12
Ross River virus infection in a traveller returning from northern Australia. ( 19727811 )
2009
13
Predictive indicators for Ross River virus infection in the Darwin area of tropical northern Australia, using long-term mosquito trapping data. ( 18482196 )
2008
14
Disease suspected to be caused by Ross River virus infection of horses. ( 18782422 )
2008
15
Itching bites may limit Ross River virus infection. ( 12558494 )
2003
16
Itching bites may limit Ross River virus infection. ( 12776734 )
2003
17
Itching bites may limit Ross River virus infection. ( 12358594 )
2002
18
Persistent Ross River virus infection of murine macrophages: an in vitro model for the study of viral relapse and immune modulation during long-term infection. ( 12359430 )
2002
19
Detection of viral ribonucleic acid and histologic analysis of inflamed synovium in Ross River virus infection. ( 10693876 )
2000
20
Specific ablation of antiviral gene expression in macrophages by antibody-dependent enhancement of Ross River virus infection. ( 10954537 )
2000
21
Ross River virus infection: FactSheet. ( 12105475 )
2000
22
A cluster of locally-acquired Ross River virus infection in outer western Sydney. ( 12105476 )
2000
23
Corticosteroids for the complications of Ross River virus infection. ( 9469192 )
1998
24
Ross River virus infection in the north-west outskirts of the Sydney basin. ( 9648366 )
1998
25
Surveillance for Ross River virus infection using blood donors. ( 9660453 )
1998
26
Corticosteroids for the complications of Ross River virus infection. ( 9729132 )
1998
27
Communicable diseases surveillance. Ross River virus infection reports increasing. ( 9079591 )
1997
28
Ross River virus infection. Diagnosis and treatment by general practitioners in South Australia. ( 9197059 )
1997
29
Health impact assessments of malaria and Ross River virus infection in the Southern Highlands Province of Papua New Guinea. ( 10365566 )
1997
30
IgG avidity in the diagnosis of acute Ross River virus infection. ( 8718789 )
1996
31
Ross River virus infection on the North Coast of New South Wales. ( 8799074 )
1996
32
Transfusions: how many cases of Ross River virus infection do we cause? ( 7565220 )
1995
33
Acute symptoms and sequelae of Ross River virus infection in South-Western Australia: a follow-up study. ( 15566808 )
1995
34
Development of a candidate vaccine against Ross River virus infection. ( 7998422 )
1994
35
Ross River virus infection. ( 8193015 )
1994
36
Update on Ross River fever. ( 8280003 )
1993
37
Evidence for meningitis in Ross River virus infection. ( 8412935 )
1993
38
Specific IgA antibody response in Ross River virus infection. ( 2834291 )
1987
39
Ross River virus infection and epidemic polyarthritis. ( 3032136 )
1987
40
Ross River virus infection of human synovial cells in vitro. ( 2994612 )
1985
41
Absence of intrauterine infection following Ross River virus infection during pregnancy. ( 6089601 )
1984
42
Absence of intrauterine infection following Ross River virus infection during pregnancy. ( 6305223 )
1983
43
Ross River Virus infection--an acute polyarthritis caused by arbovirus. ( 6319696 )
1983
44
Experimental viral polymyositis: age dependency and immune responses to Ross River virus infection in mice. ( 6264346 )
1981
45
An epidemic of Ross River virus infection in Fiji, 1979. ( 7283004 )
1981
46
Epidemic polyarthritis (Ross River) virus infection in the Cook Islands. ( 7325286 )
1981
47
Possible genetic determinants in epidemic polyarthritis caused by Ross River virus infection. ( 6260071 )
1980
48
Pathogenesis of Ross River virus infection in mice. I. Ependymal infection, cortical thinning, and hydrocephalus. ( 4632038 )
1973
49
Pathogenesis of Ross River virus infection in mice. II. Muscle, heart, and brown fat lesions. ( 4632039 )
1973

Variations for Ross River Fever

Expression for Ross River Fever

Search GEO for disease gene expression data for Ross River Fever.

Pathways for Ross River Fever

Pathways related to Ross River Fever according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.31 COMP IL10

GO Terms for Ross River Fever

Biological processes related to Ross River Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.26 COMT IL10
2 regulation of gene expression GO:0010468 9.16 COMP IL10
3 response to lipopolysaccharide GO:0032496 8.96 COMT IL10
4 regulation of sensory perception of pain GO:0051930 8.62 COMT IL10

Sources for Ross River Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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