MCID: RSS001
MIFTS: 28

Ross River Fever

Categories: Bone diseases, Infectious diseases

Aliases & Classifications for Ross River Fever

MalaCards integrated aliases for Ross River Fever:

Name: Ross River Fever 12 15 70
Ross River Virus Infection 70
Ross River Virus Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050518
UMLS 70 C0035865 C0919833

Summaries for Ross River Fever

Disease Ontology : 12 A viral infectious disease that results in infection located in joint, has material basis in Ross River virus, which is transmitted by Culex, and transmitted by Aedes mosquitoes. The infection has symptom fever, has symptom arthralgia, and has symptom rash.

MalaCards based summary : Ross River Fever, also known as ross river virus infection, is related to chikungunya and exanthem, and has symptoms including fever, arthralgia and rash. An important gene associated with Ross River Fever is MXRA8 (Matrix Remodeling Associated 8), and among its related pathways/superpathways are Lung fibrosis and amb2 Integrin signaling. The drugs Aluminum hydroxide and Formaldehyde have been mentioned in the context of this disorder. Affiliated tissues include joint and t cells.

Wikipedia : 73 Ross River fever is a mosquito-borne infectious disease caused by infection with the Ross River virus.... more...

Related Diseases for Ross River Fever

Graphical network of the top 20 diseases related to Ross River Fever:



Diseases related to Ross River Fever

Symptoms & Phenotypes for Ross River Fever

Symptoms:

12
  • fever
  • arthralgia
  • rash

Drugs & Therapeutics for Ross River Fever

Drugs for Ross River Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aluminum hydroxide Approved, Investigational Phase 3 21645-51-2
2
Formaldehyde Approved, Vet_approved Phase 3 50-00-0 712
3 Vaccines Phase 3
4 Disinfectants Phase 1, Phase 2
5 Anti-Infective Agents Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase 3 Study to Assess the Immunogenicity, Safety, and Consistency of Lot Manufacture of Ross River Virus (RRV) Vaccine in Healthy Male and Female Subjects 16 Years of Age and Older Completed NCT01242670 Phase 3
2 Open-label Phase 3b Study to Investigate the Safety of Ross River Virus (RRV) Vaccine From 6 to 12 Months After the Third Vaccination in Healthy Adults (Follow up to Precursor Study 880801) Completed NCT01604746 Phase 3
3 A Blinded Phase 1/2 Dose Escalation Study to Assess Safety and Immunogenicity and Investigate the Optimal Dose Level of a Formalin-Treated, UV-Inactivated, Vero Cell-Derived Ross River Virus (RRV) Vaccine in Healthy Volunteers Aged 18 to 40 Years Completed NCT00717834 Phase 1, Phase 2

Search NIH Clinical Center for Ross River Fever

Genetic Tests for Ross River Fever

Anatomical Context for Ross River Fever

The Foundational Model of Anatomy Ontology organs/tissues related to Ross River Fever:

19
Joint

MalaCards organs/tissues related to Ross River Fever:

40
T Cells

Publications for Ross River Fever

Articles related to Ross River Fever:

(show top 50) (show all 82)
# Title Authors PMID Year
1
Ross River Virus Infection: A Cross-Disciplinary Review with a Veterinary Perspective. 61
33802851 2021
2
Plasmacytoid Dendritic Cells Mediate Control of Ross River Virus Infection via a Type I Interferon-Dependent, MAVS-Independent Mechanism. 61
33361425 2021
3
Species Traits and Hotspots Associated with Ross River Virus Infection in Nonhuman Vertebrates in South East Queensland. 61
32996845 2021
4
Ross River Virus Infection of Horses: Appraisal of Ecological and Clinical Consequences. 61
32972681 2020
5
Associations Between Ross River Virus Infection in Humans and Vector-Vertebrate Community Ecology in Brisbane, Australia. 61
32366183 2020
6
The geography of Ross River virus infection in South Australia, 2000-2013. 61
32418511 2020
7
Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease. 61
32365139 2020
8
A Factor I-Like Activity Associated with Chikungunya Virus Contributes to Its Resistance to the Human Complement System. 61
31941783 2020
9
Ecological and life history traits are associated with Ross River virus infection among sylvatic mammals in Australia. 61
30646881 2019
10
Mosquito and Virus Surveillance as a Predictor of Human Ross River Virus Infection in South-West Western Australia: How Useful Is It? 61
30182918 2018
11
Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes. 61
29377936 2018
12
Increased Proinflammatory Cytokine Levels in Prolonged Arthralgia in Ross River Virus Infection. 61
28322700 2017
13
An overview of the epidemiology of notifiable infectious diseases in Australia, 1991-2011. 61
27586156 2016
14
Re-evaluating the residual risk of transfusion-transmitted Ross River virus infection. 61
26748600 2016
15
Ross River virus infection in a Thuringian traveller returning from south-east Australia. 61
25380568 2015
16
First reported case of transfusion-transmitted Ross River virus infection. 61
25758699 2015
17
Purpuric exanthem caused by Ross River virus infection. 61
25551310 2015
18
CD8+ T cells control Ross River virus infection in musculoskeletal tissues of infected mice. 61
25488988 2015
19
Osteoblasts from osteoarthritis patients show enhanced susceptibility to Ross River virus infection associated with delayed type I interferon responses. 61
25407789 2014
20
The seroprevalence and factors associated with Ross river virus infection in western grey kangaroos (Macropus fuliginosus) in Western Australia. 61
25325318 2014
21
Ross River virus infection surveillance in the Greater Perth Metropolitan area--has there been an increase in cases in the winter months? 61
25222206 2014
22
Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection. 61
24429363 2014
23
Neurocognitive disturbances associated with acute infectious mononucleosis, Ross River fever and Q fever: a preliminary investigation of inflammatory and genetic correlates. 61
24211375 2014
24
Geographic Information Systems used to describe the link between the risk of Ross River virus infection and proximity to the Leschenault estuary, WA. 61
22672028 2012
25
Ross River virus infection in a traveller returning from northern Australia. 61
19727811 2009
26
Disease suspected to be caused by Ross River virus infection of horses. 61
18782422 2008
27
Predictive indicators for Ross River virus infection in the Darwin area of tropical northern Australia, using long-term mosquito trapping data. 61
18482196 2008
28
Ross River virus and Barmah Forest virus infections: a review of history, ecology, and predictive models, with implications for tropical northern Australia. 61
18279007 2008
29
Climate change and the transmission of vector-borne diseases: a review. 61
19124300 2008
30
Ross River virus disease reemergence, Fiji, 2003-2004. 61
15829203 2005
31
Reactive arthritis and vasculitis in a child due to Ross River virus infection. 61
15588219 2004
32
Itching bites may limit Ross River virus infection. 61
12558494 2003
33
Itching bites may limit Ross River virus infection. 61
12776734 2003
34
Itching bites may limit Ross River virus infection. 61
12358594 2002
35
Persistent Ross River virus infection of murine macrophages: an in vitro model for the study of viral relapse and immune modulation during long-term infection. 61
12359430 2002
36
Geographic variation of notified Ross River virus infections in Queensland, Australia, 1985-1996. 61
11561698 2001
37
Specific ablation of antiviral gene expression in macrophages by antibody-dependent enhancement of Ross River virus infection. 61
10954537 2000
38
A cluster of locally-acquired Ross River virus infection in outer western Sydney. 61
12105476 2000
39
Ross River virus infection: FactSheet. 61
12105475 2000
40
Detection of viral ribonucleic acid and histologic analysis of inflamed synovium in Ross River virus infection. 61
10693876 2000
41
[Increased travelling--increased risk of imported viruses. A review of the diagnostic capacity of the Swedish Institute for Infectious Disease Control]. 61
10405531 1999
42
Corticosteroids for the complications of Ross River virus infection. 61
9729132 1998
43
Ross River virus infection in the north-west outskirts of the Sydney basin. 61
9648366 1998
44
Surveillance for Ross River virus infection using blood donors. 61
9660453 1998
45
Corticosteroids for the complications of Ross River virus infection. 61
9469192 1998
46
Self-reported morbidity of Barmah Forest virus infection on the north coast of New South Wales. 61
9397039 1997
47
Australia's notifiable diseases status, 1996. Annual report of the National Notifiable Diseases Surveillance System. 61
9339602 1997
48
Ross River virus infection. Diagnosis and treatment by general practitioners in South Australia. 61
9197059 1997
49
Health impact assessments of malaria and Ross River virus infection in the Southern Highlands Province of Papua New Guinea. 61
10365566 1997
50
Communicable diseases surveillance. Ross River virus infection reports increasing. 61
9079591 1997

Variations for Ross River Fever

Expression for Ross River Fever

Search GEO for disease gene expression data for Ross River Fever.

Pathways for Ross River Fever

Pathways related to Ross River Fever according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.96 PTX3 IL6
2 10.64 JAM2 IL6
3 10.19 IL6 HPR

GO Terms for Ross River Fever

Biological processes related to Ross River Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 maintenance of permeability of blood-brain barrier GO:0035633 8.62 JAM2 IL6

Sources for Ross River Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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