MCID: SCR024
MIFTS: 28

Sacrococcygeal Teratoma

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Sacrococcygeal Teratoma

MalaCards integrated aliases for Sacrococcygeal Teratoma:

Name: Sacrococcygeal Teratoma 20 58 70

Classifications:



External Ids:

ICD10 via Orphanet 33 C41.4
Orphanet 58 ORPHA494421
UMLS 70 C0559459

Summaries for Sacrococcygeal Teratoma

GARD : 20 A sacrococcygeal teratoma is a tumor that grows at the base of the spine in a developing fetus. It occurs in one in 40,000 newborns and girls are four times more likely to be affected than boys. Though it is usually benign, there is a possibility that the teratoma could become malignant. As such, the recommended treatment of a teratoma is complete removal of the tumor by surgery, performed soon after the birth. If not all of the tumor is removed during the initial surgery, the teratoma may grow back ( recur ) and additional surgeries may be needed. Studies have found that sacrococcygeal teratomas recur in up to 22% of cases.

MalaCards based summary : Sacrococcygeal Teratoma is related to teratoma and chromosomal triplication. An important gene associated with Sacrococcygeal Teratoma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways is Glucocorticoid receptor regulatory network. Affiliated tissues include Primitive Streak, bone and spinal cord.

Wikipedia : 73 Sacrococcygeal teratoma (SCT) is a type of tumor known as a teratoma that develops at the base of the... more...

Related Diseases for Sacrococcygeal Teratoma

Diseases related to Sacrococcygeal Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 172)
# Related Disease Score Top Affiliating Genes
1 teratoma 30.8 MNX1 CGB7 CGA AFP
2 chromosomal triplication 30.3 CGB7 AFP
3 meningocele 30.3 MNX1 AFP
4 benign teratoma 30.1 MNX1 AFP
5 oligohydramnios 29.9 CGA AFP
6 hydrocele 29.7 CGA AFP
7 neural tube defects 29.3 MNX1 CGB7 AFP
8 scott syndrome 10.7
9 mature teratoma 10.6
10 polyhydramnios 10.6
11 hydrops fetalis, nonimmune 10.5
12 lymphatic malformation 7 10.5
13 neurogenic bladder 10.5
14 hydronephrosis 10.5
15 constipation 10.5
16 endodermal sinus tumor 10.4
17 myelomeningocele 10.4
18 germ cells tumors 10.4
19 testicular yolk sac tumor 10.4
20 rare tumor 10.3
21 malignant teratoma 10.3
22 pre-eclampsia 10.2
23 cystic teratoma 10.2
24 mucinous adenocarcinoma 10.2
25 embryonal carcinoma 10.2
26 appendix adenocarcinoma 10.2
27 diaphragmatic hernia, congenital 10.2
28 currarino syndrome 10.2
29 vesicoureteral reflux 1 10.2
30 schinzel-giedion midface retraction syndrome 10.2
31 patau syndrome 10.2
32 hemangioma 10.2
33 extragonadal germ cell cancer 10.2
34 urinary tract obstruction 10.2
35 paraplegia 10.2
36 neuroblastoma 10.2
37 extragonadal teratoma 10.2
38 cornelia de lange syndrome 1 10.1
39 renal hypodysplasia/aplasia 1 10.1
40 wilms tumor 1 10.1
41 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.1
42 lipomyelomeningocele 10.1
43 proteinuria, chronic benign 10.1
44 deficiency anemia 10.1
45 cardiac arrest 10.1
46 urinary tract infection 10.1
47 hypospadias 10.1
48 microcephaly 10.1
49 disseminated intravascular coagulation 10.1
50 pyelonephritis 10.1

Graphical network of the top 20 diseases related to Sacrococcygeal Teratoma:



Diseases related to Sacrococcygeal Teratoma

Symptoms & Phenotypes for Sacrococcygeal Teratoma

Drugs & Therapeutics for Sacrococcygeal Teratoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Improving Prenatal Parental Counseling in Cases of Sacrococcygeal Teratoma: a Multicenter Retrospective Study With Review of the Literature Recruiting NCT04623658

Search NIH Clinical Center for Sacrococcygeal Teratoma

Genetic Tests for Sacrococcygeal Teratoma

Anatomical Context for Sacrococcygeal Teratoma

MalaCards organs/tissues related to Sacrococcygeal Teratoma:

40
Bone, Spinal Cord, Uterus, Pituitary, Eye, Lymph Node, Small Intestine
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Sacrococcygeal Teratoma:
# Tissue Anatomical CompartmentCell Relevance
1 Primitive Streak Primitive Streak Affected by disease

Publications for Sacrococcygeal Teratoma

Articles related to Sacrococcygeal Teratoma:

(show top 50) (show all 812)
# Title Authors PMID Year
1
A review of adopted colorectal patients: a parent's perspective. 61
33475771 2021
2
Posterior urethral valves masquerading as neuropathic bladder following sacrococcygeal teratoma resection. 61
33661045 2021
3
Massive sacrococcygeal teratoma in a preterm infant. 61
33768807 2021
4
A large, highly vascularized sacrococcygeal teratoma in a preterm male infant: A case report. 61
33468376 2021
5
Fetal Sacrococcygeal Teratoma and the Development of Hydrops. 61
33526646 2021
6
Enema-Induced spastic left colon syndrome: An unintended consequence of chronic enema use. 61
33199058 2021
7
Malignant sacrococcygeal germ cell tumors in children in Taiwan: A retrospective single-center case series. 61
33530223 2021
8
Combined laparoscopic and posterior approach resection of large sacrococcygeal cystic teratoma. 61
33438088 2021
9
A Rare Case of Immature Sacrococcygeal Teratoma With Lymph Node Metastasis in a Neonate. 61
33323883 2020
10
Congenital Sacrococcygeal Neuroblastoma: A Report of Two Cases with Summary of Prior Published Cases. 61
33307929 2020
11
Malignant recurrence after mature Sacrococcygeal teratoma: A meta-analysis and review of the literature. 61
33142194 2020
12
Sacrococcygeal teratoma in one twin: a case report and literature review. 61
33267783 2020
13
Neonatal sacrococcygeal teratoma: Our 20-year experience from a tertiary care centre in North India. 61
33356941 2020
14
A case of an asymptomatic sacrococcygeal teratoma diagnosed in adulthood. 61
33294159 2020
15
Adult case of giant sacrococcygeal teratoma: case report. 61
33234106 2020
16
Long-term functional outcome of sacrococcygeal teratoma after resection in neonates and infants: a single-center experience. 61
32990839 2020
17
A novel TSC1 variant associated with tuberous sclerosis and sacrococcygeal teratoma. 61
33298910 2020
18
Prenatal genetic diagnosis: Fetal therapy as a possible solution to a positive test. 61
33170180 2020
19
Significant rate of lower urinary tract dysfunction in patients with sacrococcygeal teratomas. 61
32563692 2020
20
Sacrococcygeal teratoma with intraspinal extension: A case series and review of literature. 61
32115228 2020
21
A Rare Case of Sacrococcygeal Teratoma in Adult. 61
33088141 2020
22
Diagnostic accuracy of serum alpha-fetoprotein levels in diagnosing recurrent sacrococcygeal teratoma: A systematic review. 61
32376010 2020
23
Description of a giant hypothalamic hamartoma associated with an immature ruptured giant sacrococcygeal teratoma: a case report. 61
32978641 2020
24
Evaluation of prenatally diagnosed fetal sacrococcygeal teratomas: A case series of seventeen pregnancies from South-central Turkey. 61
33072420 2020
25
Surgical outcomes of bladder augmentation: A comparison of three different augmentation procedures. 61
32874978 2020
26
Total Laparoscopic Excision of an Altman Type IV Sacrococcygeal Teratoma with the Assistance of Intraoperative Transrectal Sonography. 61
32717419 2020
27
Sacrococcygeal Teratoma: A Case Report. 61
32827016 2020
28
Tunical Gliomatosis: An Uncommon Histological Entity. 61
32720553 2020
29
Sacrococcygeal teratoma with preterm delivery: a case report. 61
32552844 2020
30
Fetal anesthesia: intrauterine therapies and immediate postnatal anesthesia for noncardiac surgical interventions. 61
32324666 2020
31
From Sacrum to Spine: A Complex Case of Sacrococcygeal Teratoma. 61
32457189 2020
32
Preoperative giant sacrococcygeal teratoma embolization in a newborn - A case report and a review. 61
32250074 2020
33
Health-related quality of life and scar satisfaction in a cohort of children operated on for sacrococcygeal teratoma. 61
32303229 2020
34
Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis. 61
32139986 2020
35
Sacrococcygeal teratoma in an adult containing a mucinous adenocarcinoma. 61
32051161 2020
36
Sacrococcygeal teratoma: control of catastrophic haemorrhage. 61
30767354 2020
37
A Vague Gluteal Swelling in a Neonate: Challenges in Its Diagnosis and Management. Short Title-Sacroccoygeal Teratoma. 61
33403226 2020
38
Percutaneous Intratumor Laser Ablation for Fetal Sacrococcygeal Teratoma. 61
31291630 2020
39
Germline Sequencing Identifies Rare Variants in Finnish Subjects with Familial Germ Cell Tumors. 61
32636668 2020
40
Mature Cystic Teratoma of Spinal Cord in a 16-Year-Old Male: A Case Report. 61
32095150 2020
41
Sacrococcygeal Teratoma: Clinical Characteristics, Management, and Long-term Outcomes in a Prospective Study from a Tertiary Care Center. 61
31896894 2020
42
Intraoperative surfactant administration during neonatal sacrococcygeal teratoma resection. 61
31433547 2019
43
Need for urodynamic evaluation as a regular follow-up tool in assessment of long-term urological outcomes in patients with sacrococcygeal teratoma. 61
30686521 2019
44
Differentiating presacral masses in anorectal malformations and isolated sacrococcygeal teratomas. 61
31256295 2019
45
Adult sacrococcygeal teratoma: a retrospective study over eight years at a single institution. 61
31273964 2019
46
Functional outcome and health-related quality of life in patients with sacrococcygeal teratoma - a Swedish multicenter study. 61
30420172 2019
47
Unresectable recurrence malignant sacrococcygeal teratoma in children treated with chemoradiotherapy: Case report and literature review. 61
31293363 2019
48
Sacrococcygeal teratoma: Nationwide survey and guidelines. 61
31359538 2019
49
Japanese clinical practice guidelines for sacrococcygeal teratoma, 2017. 61
30903638 2019
50
Signet ring cell carcinoma arising from sacrococcygeal teratoma: a case report and review of the literature. 61
30832522 2019

Variations for Sacrococcygeal Teratoma

Expression for Sacrococcygeal Teratoma

Search GEO for disease gene expression data for Sacrococcygeal Teratoma.

Pathways for Sacrococcygeal Teratoma

Pathways related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.54 CGA AFP

GO Terms for Sacrococcygeal Teratoma

Molecular functions related to Sacrococcygeal Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 CGB7 CGA

Sources for Sacrococcygeal Teratoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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