MCID: SGT001
MIFTS: 34

Sagittal Sinus Thrombosis

Categories: Cardiovascular diseases, Neuronal diseases, Blood diseases

Aliases & Classifications for Sagittal Sinus Thrombosis

MalaCards integrated aliases for Sagittal Sinus Thrombosis:

Name: Sagittal Sinus Thrombosis 12 55 44 15 73
Thrombosis of Superior Longitudinal Sinus 12
Thrombosis of Superior Sagittal Sinus 12
Thrombosis Superior Sagittal Sinus 55

Classifications:



External Ids:

Disease Ontology 12 DOID:3576
MeSH 44 D020225
SNOMED-CT 68 192760003 70607008
UMLS 73 C0338575

Summaries for Sagittal Sinus Thrombosis

MalaCards based summary : Sagittal Sinus Thrombosis, also known as thrombosis of superior longitudinal sinus, is related to heparin-induced thrombocytopenia and thrombosis. An important gene associated with Sagittal Sinus Thrombosis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include brain, myeloid and b cells.

Related Diseases for Sagittal Sinus Thrombosis

Diseases related to Sagittal Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 192)
# Related Disease Score Top Affiliating Genes
1 heparin-induced thrombocytopenia 30.6 F3 SERPINC1
2 thrombosis 30.2 F2 F3 F5 SERPINC1
3 homocystinuria 29.6 F5 SERPINC1
4 purpura 29.5 F2 F3 SERPINC1
5 protein c deficiency 29.5 F2 F5 SERPINC1
6 antithrombin iii deficiency 29.3 F2 F5 SERPINC1
7 dysfibrinogenemia 29.3 F2 F5 SERPINC1
8 protein s deficiency 29.2 F2 F3 F5 SERPINC1
9 intracranial hypertension 29.0 F2 F3 F5 SERPINC1
10 pulmonary embolism 28.7 F2 F3 F5 SERPINC1
11 thrombophilia due to thrombin defect 28.5 F2 F3 F5 SERPINC1
12 budd-chiari syndrome 28.5 F2 F3 F5 SERPINC1
13 antiphospholipid syndrome 28.5 F2 F3 F5 SERPINC1
14 angina pectoris 10.4 F3 SERPINC1
15 blood protein disease 10.4 F2 SERPINC1
16 alpha-2-plasmin inhibitor deficiency 10.4 F2 SERPINC1
17 coronary thrombosis 10.4 F3 SERPINC1
18 intermediate coronary syndrome 10.3 F3 SERPINC1
19 anterior spinal artery syndrome 10.3 F2 SERPINC1
20 cerebral falx meningioma 10.3 F2 F3
21 subendocardial myocardial infarction 10.3 F2 SERPINC1
22 pulmonary immaturity 10.3 F3 SERPINC1
23 qualitative platelet defect 10.3 F2 F3
24 esophageal varix 10.3 F2 SERPINC1
25 von willebrand disease, type 1 10.3 F2 F3
26 femoral neuropathy 10.3 F2 F3
27 alcohol-related birth defect 10.3 F2 F3
28 hantavirus pulmonary syndrome 10.3 F2 F3
29 hypersplenism 10.3 F2 SERPINC1
30 anterior cranial fossa meningioma 10.3 F2 F3
31 hepatic veno-occlusive disease 10.3 F3 SERPINC1
32 splenic disease 10.3 F2 F3
33 sticky platelet syndrome 10.2 F5 SERPINC1
34 nephrotic syndrome 10.2
35 hemophilia 10.2 F2 F3
36 acquired hemophilia a 10.2 F3 F5
37 leukemia 10.2
38 head injury 10.2
39 acquired hemophilia 10.2 F3 F5
40 endocardium disease 10.2 F2 F3
41 meningococcemia 10.2 F5 SERPINC1
42 analbuminemia 10.2 F2 F3
43 cerebritis 10.2
44 headache 10.2
45 catastrophic antiphospholipid syndrome 10.2 F3 F5
46 legg-calve-perthes disease 10.2 F5 SERPINC1
47 squamous cell papilloma 10.1 F2 F3
48 intermittent claudication 10.1 F2 SERPINC1
49 paracetamol poisoning 10.1 F2 F5
50 livedoid vasculopathy 10.1 F2 F5

Graphical network of the top 20 diseases related to Sagittal Sinus Thrombosis:



Diseases related to Sagittal Sinus Thrombosis

Symptoms & Phenotypes for Sagittal Sinus Thrombosis

Drugs & Therapeutics for Sagittal Sinus Thrombosis

Search Clinical Trials , NIH Clinical Center for Sagittal Sinus Thrombosis

Cochrane evidence based reviews: sagittal sinus thrombosis

Genetic Tests for Sagittal Sinus Thrombosis

Anatomical Context for Sagittal Sinus Thrombosis

MalaCards organs/tissues related to Sagittal Sinus Thrombosis:

41
Brain, Myeloid, B Cells, T Cells, Bone, Bone Marrow

Publications for Sagittal Sinus Thrombosis

Articles related to Sagittal Sinus Thrombosis:

(show top 50) (show all 202)
# Title Authors Year
1
Superior sagittal sinus thrombosis in a case of Mixed Connective Tissue Disease. ( 29848537 )
2018
2
Congenital dysfibrinogenemia in a Japanese family with fibrinogen Naples (BI^Ala68Thr) manifesting as superior sagittal sinus thrombosis. ( 28537987 )
2017
3
Sagittal sinus thrombosis in JAK2-V617F mutation without overt myeloproliferative disorder. ( 28228434 )
2017
4
Papilledema secondary to a superior sagittal sinus thrombosis. Mantle cell lymphoma paraneoplastic syndrome. ( 26596713 )
2016
5
Superior sagittal sinus thrombosis in a patient with acute lymphoblastic leukemia. ( 28038855 )
2016
6
Superior sagittal sinus thrombosis after intrathecal chemotherapy and intravenous high-dose cytarabine in an acute myeloid leukemia case with t(8;21)(q22;q22). ( 27169454 )
2016
7
Superior Sagittal Sinus Thrombosis Related to the Use of Tamoxifen: A Case Report and Review of Literature. ( 29782786 )
2016
8
Treatment of the Superior Sagittal Sinus Thrombosis with the Mechanical Thrombectomy Using Stent-Retriever Device. ( 27651872 )
2016
9
Multiple Dural and Pial Arteriovenous Fistulae in a Twenty-Four-Year-Old Woman in the Setting of Superior Sagittal Sinus Thrombosis: Case Report and Review of Literature. ( 27544867 )
2016
10
Superior sagittal sinus thrombosis as the initial presentation of renal cell carcinoma. ( 25829662 )
2015
11
Sagittal sinus thrombosis in puerperium. ( 26229306 )
2015
12
Postdural Puncture Superior Sagittal Sinus Thrombosis in a Juvenile Case of Clinically Isolated Syndrome. ( 26558127 )
2015
13
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. ( 24692369 )
2014
14
Antegrade rheolytic thrombectomy and thrombolysis for superior sagittal sinus thrombosis using burr hole access. ( 24699566 )
2014
15
Acquired Pial and Dural Arteriovenous Fistulae following Superior Sagittal Sinus Thrombosis in Patients with Protein S Deficiency: A Report of Two Cases. ( 24162240 )
2013
16
Acute presentation of sagittal sinus thrombosis following closed head injury without overlying fracture. ( 23307334 )
2013
17
Macrocephaly-capillary malformation syndrome in a newborn with tetralogy of fallot and sagittal sinus thrombosis. ( 22451530 )
2013
18
Pseudotumor cerebri in a case of ulcerative colitis with sagittal sinus thrombosis. ( 23549165 )
2013
19
Right Atrial Thrombosis associated with Sagittal Sinus Thrombosis caused by Protein C-S Deficiency. ( 24362664 )
2013
20
Superior sagittal sinus thrombosis as a treatment complication of nonsyndromic KleeblattschAodel. ( 24220397 )
2013
21
Sagittal sinus thrombosis with malignant brain oedema: pathophysiology of cortical veins after decompressive craniectomy. ( 23397272 )
2013
22
Post-traumatic sagittal sinus thrombosis: case report. ( 23588984 )
2013
23
Comparison of anticoagulation and thrombolysis treatments in a rat model of superior sagittal sinus thrombosis. ( 24195615 )
2013
24
Transient ischaemic attack: an exceptional presenting syndrome of a superior sagittal sinus thrombosis. ( 24265341 )
2013
25
An unusual case of transient cortical blindness with sagittal sinus thrombosis in a case of Henoch-Schonlein purpura. ( 22864046 )
2012
26
The role of hyperthyroidism as the predisposing factor for superior sagittal sinus thrombosis. ( 23210057 )
2012
27
Periorbital cellulitis, subgaleal abscess and superior sagittal sinus thrombosis: a rare combination of complications arising from unilateral frontal sinusitis. ( 23020898 )
2012
28
A novel protein S gene mutation combined with protein S Tokushima mutation in a patient with superior sagittal sinus thrombosis. ( 21647728 )
2012
29
Superior sagittal sinus thrombosis complicating typhoid Fever in a teenager. ( 23227403 )
2012
30
Bilateral optic disc swelling as a presenting sign of superior sagittal sinus thrombosis. ( 22987907 )
2012
31
Sagittal sinus thrombosis while on tamoxifen requiring craniectomy. ( 22720357 )
2012
32
Isolated inferior sagittal sinus thrombosis caused by a rare combination of elevated lipoprotein (a) and iron deficiency anemia. ( 23022905 )
2012
33
A rare complication in a child undergoing chemotherapy for acute lymphoblastic leukemia: superior sagittal sinus thrombosis. ( 21463850 )
2011
34
Pulmonary embolus from acute superior sagittal sinus thrombosis secondary to skull fracture: case report. ( 21389895 )
2011
35
Superior sagittal sinus thrombosis complicating neck dissection. ( 20298643 )
2010
36
Intracranial hypertension caused by a depressed skull fracture resulting in superior sagittal sinus thrombosis in a pediatric patient: treatment with ventriculoperitoneal shunt insertion. ( 20593983 )
2010
37
A case of superior sagittal sinus thrombosis in pregnancy despite prophylactic antenatal heparin. ( 21126134 )
2010
38
Sagittal sinus thrombosis due to L-asparaginase. ( 21042505 )
2010
39
Anesthesia for cesarean delivery in the term pregnant following acute onset severe intracranial superior sagittal sinus thrombosis. ( 19961118 )
2009
40
Superior sagittal sinus thrombosis presenting as a continuous headache: a case report and review of the literature. ( 20062608 )
2009
41
Susceptibility-weighted magnetic resonance imaging detects impaired cerebral hemodynamics in the superior sagittal sinus thrombosis--case report. ( 19556733 )
2009
42
Cortical blindness due to sagittal sinus thrombosis in acute lymphoblastic leukaemia. ( 19006563 )
2009
43
Detection of superior sagittal sinus thrombosis on FDG PET. ( 19352280 )
2009
44
[Sagittal sinus thrombosis as a rare cause of postpartum headache: a case report]. ( 18853684 )
2008
45
Protein S deficiency, epileptic seizures, sagittal sinus thrombosis and hemorrhagic infarction after ingestion of dimenhydrinate. ( 18382986 )
2008
46
Hyperemesis gravidarum and first trimester sagittal sinus thrombosis. ( 18604696 )
2008
47
Bulky scalp metastasis and superior sagittal sinus thrombosis from a cervical adenocarcinoma: an unusual case. ( 18373834 )
2008
48
Superior sagittal sinus thrombosis: subtle signs on neuroimaging. ( 18536826 )
2008
49
Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage. ( 17582771 )
2007
50
Superior sagittal sinus thrombosis and bilateral sixth-nerve palsy in a child with nephrotic syndrome. ( 17333003 )
2007

Variations for Sagittal Sinus Thrombosis

Expression for Sagittal Sinus Thrombosis

Search GEO for disease gene expression data for Sagittal Sinus Thrombosis.

Pathways for Sagittal Sinus Thrombosis

GO Terms for Sagittal Sinus Thrombosis

Cellular components related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.65 BLVRA CTSH F2 F3 SERPINC1
2 extracellular region GO:0005576 9.55 CTSH F2 F3 F5 SERPINC1
3 endoplasmic reticulum lumen GO:0005788 9.13 F2 F5 SERPINC1
4 extracellular space GO:0005615 9.02 CTSH F2 F3 F5 SERPINC1

Biological processes related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.46 CTSH F2 F5 SERPINC1
2 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.32 CTSH F3
3 regulation of blood coagulation GO:0030193 9.26 F2 SERPINC1
4 blood coagulation GO:0007596 9.26 F2 F3 F5 SERPINC1
5 hemostasis GO:0007599 8.92 F2 F3 F5 SERPINC1

Molecular functions related to Sagittal Sinus Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 8.8 CTSH F2 F3

Sources for Sagittal Sinus Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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