MCID: SLM003
MIFTS: 54

Salmonellosis

Categories: Blood diseases, Immune diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Salmonellosis

MalaCards integrated aliases for Salmonellosis:

Name: Salmonellosis 12 74 3 15 71
Salmonella Infections 54 42 17 71
Salmonella Infection 12 3 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060859
ICD9CM 34 003.0
UMLS 71 C0036117 C2945607

Summaries for Salmonellosis

MedlinePlus : 42 Salmonella is the name of a group of bacteria. In the United States, it is a common cause of foodborne illness. Salmonella occurs in raw poultry, eggs, beef, and sometimes on unwashed fruit and vegetables. You also can get infected after handling pets, especially reptiles like snakes, turtles, and lizards. Symptoms include Fever Diarrhea Abdominal cramps Headache Possible nausea, vomiting, and loss of appetite Symptoms usually last 4-7 days. Your health care provider diagnoses the infection with a stool test. Most people get better without treatment. Infection can be more serious in older adults, infants, and people with chronic health problems. If Salmonella gets into the bloodstream, it can be serious. The usual treatment is antibiotics. Typhoid fever, a more serious disease caused by Salmonella, is not common in the United States. It frequently occurs in developing countries. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Salmonellosis, also known as salmonella infections, is related to typhoid fever and gastroenteritis, and has symptoms including fever and pruritus. An important gene associated with Salmonellosis is IL12RB1 (Interleukin 12 Receptor Subunit Beta 1), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Ceftriaxone and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and liver, and related phenotypes are Increased viability and cardiovascular system

Disease Ontology : 12 A primary bacterial infectious disease caused by the bacteria of the genus Salmonella. It has sypmtoms diarrhea, fever, vomiting, and abdominal cramps 12 to 72 hours after infection. In most cases, the illness lasts four to seven days, and most people recover without treatment.

CDC : 3 Salmonella is a bacteria that makes people sick. It was discovered by an American scientist named Dr. Salmon, and has been known to cause illness for over 125 years. The illness people get from a Salmonella infection is called salmonellosis. Most people infected with Salmonella develop diarrhea, fever, and abdominal cramps between 12 and 72 hours after infection. The illness usually lasts 4 to 7 days, and most individuals recover without treatment. In some cases, diarrhea may be so severe that the patient needs to be hospitalized. In these patients, the Salmonella infection may spread from the intestines to the blood stream, and then to other body sites. In these cases, Salmonella can cause death unless the person is treated promptly with antibiotics. The elderly, infants, and those with impaired immune systems are more likely to have a severe illness1.

Wikipedia : 74 Salmonellosis is a symptomatic infection caused by bacteria of the Salmonella type. The most common... more...

Related Diseases for Salmonellosis

Diseases in the Salmonellosis family:

Rare Form of Salmonellosis

Diseases related to Salmonellosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 573)
# Related Disease Score Top Affiliating Genes
1 typhoid fever 32.4 TLR4 SPI1 SLC11A1 IL1B IFNGR1 IFNG
2 gastroenteritis 31.8 LACTB IL1B IFNG CP ALB
3 diarrhea 31.8 TLR4 IL1B IFNG GPT ALB
4 dysentery 31.6 TLR4 IL1B CCR6 ALB
5 shigellosis 31.6 TLR4 IL1B IL18 CASP1 ALB
6 schistosomiasis 31.3 IFNGR1 IFNG GPT ALB
7 brucellosis 31.2 TLR4 SLC11A1 IL18 IFNG
8 listeriosis 31.2 TLR4 IL18 CCR6
9 appendicitis 31.2 TLR4 IL1B IFNG ALB
10 osteomyelitis 31.2 TLR4 STAT1 IL1B IFNGR1 IFNG CASP1
11 septic arthritis 31.1 TLR4 IFNG DEFB4A
12 peritonitis 31.1 TLR4 IL1B IL18 IFNG ALB
13 campylobacteriosis 31.0 VDR TLR4 STAT1 SLC11A1 JUN IL1B
14 acute kidney failure 31.0 IL18 GPT ALB
15 lung abscess 31.0 LACTB IFNG ALB
16 cholecystitis 31.0 TLR4 GPT CP ALB
17 ulcerative colitis 30.9 TLR4 IL1B IFNG CCR6
18 bronchopneumonia 30.9 TLR4 GPT ALB
19 histoplasmosis 30.9 STAT1 IFNG CCR6
20 acquired immunodeficiency syndrome 30.9 IL1B IFNG CCR6 CASP1 ALB
21 reactive arthritis 30.9 TLR4 SLC11A1 IL1B IFNG CCR6
22 pericarditis 30.9 IL1B IFNG ALB
23 plague 30.9 TLR4 CASP1 ALB
24 splenic abscess 30.8 LACTB GPT ALB
25 toxic shock syndrome 30.8 TLR4 IL1B IFNG
26 acute cystitis 30.8 TLR4 IL18 GPT CCR6 ALB
27 endocarditis 30.7 LACTB IFNG ALB
28 nocardiosis 30.7 LACTB IL12RB1 IFNGR1
29 rheumatic disease 30.7 IL1B IL18 IFNG CCR6
30 measles 30.7 TLR4 STAT1 IL1B IFNG
31 colitis 30.7 TLR4 IL1B IL18 IFNG DEFA5 CCR6
32 chronic granulomatous disease 30.7 SLC11A1 IL1B IFNG CASP1
33 leptospirosis 30.6 IL1B IL18 IFNG
34 pyelonephritis 30.6 TLR4 IL1B IFNG GPT ALB
35 crohn's colitis 30.6 IL1B IFNG DEFA5 CCR6
36 cysticercosis 30.6 TLR4 IL1B IL18
37 nutmeg liver 30.6 GPT CP
38 viral hepatitis 30.5 TLR4 IFNG GPT CP ALB
39 melioidosis 30.5 TLR4 IL18 IFNG
40 urethritis 30.5 TLR4 DEFB4A DEFA5
41 keratitis, hereditary 30.5 TLR4 IL1B CCR6
42 helicobacter pylori infection 30.5 JUN IL1B IFNGR1
43 myocarditis 30.5 TLR4 IL1B IL18 IL12RB1 IFNG ALB
44 meningitis 30.5 TLR4 LACTB IL1B IL18 IFNG ALB
45 klebsiella pneumonia 30.5 LACTB CCR6 ALB
46 fatty liver disease 30.5 TLR4 IL1B GPT ALB
47 tularemia 30.5 TLR4 SLC11A1 IL18 CASP1
48 clostridium difficile colitis 30.4 IL1B CCR6 ALB
49 paratyphoid fever 30.4 SPI1 SLC11A1 IL1B IFNGR1 IFNG CASP1
50 chronic graft versus host disease 30.4 IFNG ALB

Comorbidity relations with Salmonellosis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Salmonellosis:



Diseases related to Salmonellosis

Symptoms & Phenotypes for Salmonellosis

UMLS symptoms related to Salmonellosis:


fever, pruritus

GenomeRNAi Phenotypes related to Salmonellosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability GR00386-A-1 9.4 ALB CASP1 DEFA5 DEFB1 IL18 IL1B

MGI Mouse Phenotypes related to Salmonellosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.32 ALB CASP1 CCR6 CP IFNG IFNGR1
2 hematopoietic system MP:0005397 10.25 CASP1 CCR6 CP IFNG IFNGR1 IL12RB1
3 homeostasis/metabolism MP:0005376 10.24 ALB CASP1 CCR6 CP IFNG IFNGR1
4 cellular MP:0005384 10.2 ALB CASP1 CP IFNG IFNGR1 IL18
5 immune system MP:0005387 10.2 ALB CASP1 CCR6 CP IFNG IFNGR1
6 digestive/alimentary MP:0005381 10.09 ALB CASP1 IFNG IFNGR1 IL18 SLC11A1
7 integument MP:0010771 9.96 CASP1 IFNG IFNGR1 IL12RB1 IL18 IL1B
8 liver/biliary system MP:0005370 9.76 ALB CP IFNG IFNGR1 JUN SPI1
9 neoplasm MP:0002006 9.61 ALB CASP1 IFNG IFNGR1 IL1B SLC11A1
10 nervous system MP:0003631 9.4 CASP1 CCR6 CP IFNG IFNGR1 IL18

Drugs & Therapeutics for Salmonellosis

Drugs for Salmonellosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
2 Anti-Infective Agents Phase 4
3 Vaccines Phase 4
4 Immunologic Factors Phase 4
5 Anti-Bacterial Agents Phase 2
6 Pharmaceutical Solutions Phase 2
7
Isoleucine Investigational, Nutraceutical Phase 2 73-32-5, 443-79-8 6306
8
Ampicillin Approved, Vet_approved 69-53-4 6249
9
Amoxicillin Approved, Vet_approved 26787-78-0 33613

Interventional clinical trials:

(show all 11)
# Name Status NCT ID Phase Drugs
1 The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis Unknown status NCT01278017 Phase 4 ceftriaxone
2 Effectiveness of a Combined Vi Vaccination and Health Education Program on Reducing the Burden of Typhoid During Childhood: A Demonstration Project in Karachi Completed NCT00125047 Phase 4
3 Immunogenicity and Safety of a Single Dose of SP093 Typhoid Vi Polysaccharide Vaccine Given in Japanese Subjects Completed NCT01608815 Phase 3
4 Exploratory Study to Evaluate the Effect of L-isoleucine Supplemented Oral Rehydration Solution in the Treatment of Acute Diarrhoea in Children and in Inducing Innate Immunity Completed NCT01034228 Phase 2
5 NCCLS Interpretive Criteria for Salmonella Completed NCT00177658
6 Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients Completed NCT00002052 Ceftriaxone sodium;Ampicillin sodium;Amoxicillin trihydrate
7 The Potential Role of the Household Environment as the Reservoir for Invasive Salmonellosis in Children, Kisangani, DR Congo. Completed NCT03073707
8 A Double Blind, Placebo Controlled, Randomised, Single Centred, Parallel Study to Determine the Potential of B-GOS, to Beneficially Influence the Wellbeing and Ageing in Healthy 52-65 Years Old Individuals Completed NCT02716350
9 Interaction Between Non-typhoid Salmonella, Host Microbiota, and Immune System During Acute Infection and Remission Recruiting NCT03494101
10 Exploring the Bottleneck Hypothesis of the Pathogenesis of Bacteraemia in an Ambulatory Outpatient Human Experimental Infection of Salmonella Typhi Recruiting NCT03889067
11 IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres Active, not recruiting NCT02689193

Search NIH Clinical Center for Salmonellosis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Chloramphenicol sodium succinate

Genetic Tests for Salmonellosis

Anatomical Context for Salmonellosis

MalaCards organs/tissues related to Salmonellosis:

40
Testes, Colon, Liver, T Cells, Kidney, Bone, Lymph Node

Publications for Salmonellosis

Articles related to Salmonellosis:

(show top 50) (show all 6834)
# Title Authors PMID Year
1
Infection, colonization and shedding of Campylobacter and Salmonella in animals and their contribution to human disease: A review. 61 42
31179637 2019
2
Helicobacter pylori infection and risk of salmonella infection. 42
30732157 2019
3
Current Challenges and Perspectives for the Use of Aqueous Plant Extracts in the Management of Bacterial Infections: The Case-Study of Salmonellaenterica Serovars. 42
30795544 2019
4
Toll-like receptor 2 variants are associated with acute reactive arthritis. 54 61
18975326 2008
5
Antimicrobial therapy of salmonelloses--current state and perspectives. 54 61
16918048 2006
6
The protective role of interleukin-18 in Salmonella infection. 54 61
11964842 2001
7
Impairment of STAT activation by IL-12 in a patient with atypical mycobacterial and staphylococcal infections. 54 61
11034424 2000
8
Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients. 54 61
9603733 1998
9
Prevalence of Campylobacter and Salmonella in African food animals and meat: A systematic review and meta-analysis. 61
31710971 2020
10
Characterization of Salmonella enterica Isolates from Selected U.S. Swine Feed Mills by Whole-Genome Sequencing. 61
31702400 2020
11
Pathogen Concentration Combined Solid-Phase PCR on Supercritical Angle Fluorescence Microlens Array for Multiplexed Detection of Invasive Nontyphoidal Salmonella Serovars. 61
31904224 2020
12
Atypical Salmonella enterica serovars in murine and human macrophage infection models. 61
32014897 2020
13
Trends in Salmonella serovars and antimicrobial resistance in pigs and poultry in Northern Ireland between 1997 and 2016. 61
31776180 2020
14
Outer membrane protein OmpV mediates Salmonella enterica serovar typhimurium adhesion to intestinal epithelial cells via fibronectin and α1β1 integrin. 61
32017350 2020
15
Zoonotic disease awareness survey of backyard poultry and swine owners in southcentral Pennsylvania. 61
32020787 2020
16
Feed additive blends fed to nursery pigs challenged with Salmonella. 61
31863091 2020
17
Role of yoaE Gene Regulated by CpxR in the Survival of Salmonella enterica Serovar Enteritidis in Antibacterial Egg White. 61
31915212 2020
18
Outbreak Characteristics and Epidemic Curves for Multistate Outbreaks of Salmonella Infections Associated with Produce: United States, 2009-2015. 61
31503506 2020
19
Dietary Supplementation of n-3 LCPUFAs Prevents Salmonellosis in a Murine Model. 61
31825613 2020
20
Characterization of Salmonella Isolates from Wastewater Treatment Plant Influents to Estimate Unreported Cases and Infection Sources of Salmonellosis. 61
31936747 2020
21
A DIVA vaccine strain lacking RpoS and the secondary messenger c-di-GMP for protection against salmonellosis in pigs. 61
31924274 2020
22
Exposures Associated with Non-Typhoidal Salmonella Infections Caused by Newport, Javiana, and Mississippi Serotypes in Tennessee, 2013-2015: A Case-Case Analysis. 61
31991616 2020
23
Single-stranded DNA (ssDNA) Aptamer targeting SipA protein inhibits Salmonella Enteritidis invasion of intestinal epithelial cells. 61
31953175 2020
24
Pathogenic Salmonella weakens avian enriched blood monocytes through ATP depletion, apoptosis induction and phagocytosis inefficiency. 61
31902485 2020
25
Vertical transmission of Salmonella Enteritidis with heterogeneous antimicrobial resistance from breeding chickens to commercial chickens in China. 61
31902488 2020
26
Prevalence of Salmonella serovars isolated from reptiles in Norwegian zoos. 61
31918736 2020
27
Retrospective Analysis of Aetiological Agents Associated with Pulmonary Mycosis Secondary to Enteric Salmonellosis in Six Horses by Panfungal Polymerase Chain Reaction. 61
31955794 2020
28
Evaluating the Risk of Salmonellosis from Dry Roasted Sunflower Seeds. 61
31804872 2020
29
Population Dynamics of Salmonella enterica within Beef Cattle Cohorts Followed from Single-Dose Metaphylactic Antibiotic Treatment until Slaughter. 61
31519659 2019
30
Prevalence and Genetic Analysis of Salmonella enterica from a Cross-Sectional Survey of the New Zealand Egg Production Environment. 61
31742446 2019
31
Onsite investigation at a mail-order hatchery following a multistate Salmonella illness outbreak linked to live poultry-United States, 2018. 61
31579916 2019
32
Molecular diversity and antibiotic resistance gene profile of Salmonella enterica serovars isolated from humans and food animals in Lagos, Nigeria. 61
31658835 2019
33
Salmonella effector SpvB interferes with intracellular iron homeostasis via regulation of transcription factor NRF2. 61
31569998 2019
34
An investigation of Salmonella Fluntern illnesses linked to leopard geckos-United States, 2018. 61
31512375 2019
35
Source Attribution of Salmonella in Macadamia Nuts to Animal and Environmental Reservoirs in Queensland, Australia. 61
31804848 2019
36
Salmonella Infection in Mesenteric Lymph Nodes of Breeding Sows. 61
31809191 2019
37
Genotypic characterization and antimicrobial resistance profile of Salmonella isolated from chicken, pork and the environment at abattoirs and supermarkets in Chongqing, China. 61
31852466 2019
38
High-content screening image dataset and quantitative image analysis of Salmonella infected human cells. 61
31843016 2019
39
Risk factors of Salmonella infection in laying hens in Menoua Division, Western region of Cameroon (Central Africa). 61
31630034 2019
40
The role of parameterization in comparing source attribution models based on microbial subtyping for salmonellosis. 61
31478354 2019
41
Complete Genome Sequences of Two Salmonella enterica subsp. enterica Serovar Anatum Strains Isolated from Papaya. 61
31806740 2019
42
Adhesive mechanism of different Salmonella fimbrial adhesins. 61
31521802 2019
43
Multiplex ligation reaction based on probe melting curve analysis: a pragmatic approach for the identification of 30 common Salmonella serovars. 61
31805936 2019
44
The Simultaneous Administration of a Probiotic or Prebiotic with Live Salmonella Vaccine Improves Growth Performance and Reduces Fecal Shedding of the Bacterium in Salmonella-Challenged Broilers. 61
31906020 2019
45
Occurrence of Salmonella infection and antimicrobial susceptibility for local Salmonella isolates from different sources in a cross-sectional study. 61
31897402 2019
46
Salmonella Infantis and Salmonella Enteritidis specific bacteriophages isolated form poultry faeces as a complementary tool for cleaning and disinfection against Salmonella. 61
31887484 2019
47
Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System. 61
31611347 2019
48
Prevalence and molecular characterization of Salmonella species associated with piglet diarrhea in North East India. 61
31867930 2019
49
Traditional Salmonella Typhimurium typing tools (phage typing and MLVA) are sufficient to resolve well-defined outbreak events only. 61
31421774 2019
50
Reference parameters of peripheral immune cell populations in broiler chickens using a large database. 61
31774310 2019

Variations for Salmonellosis

Expression for Salmonellosis

Search GEO for disease gene expression data for Salmonellosis.

Pathways for Salmonellosis

Pathways related to Salmonellosis according to GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.03 TLR4 STAT1 SLC11A1 JUN IL1B IL18
2
Show member pathways
13.71 TLR4 JUN IL1B IL18 IL12RB1 IFNGR1
3
Show member pathways
13.38 STAT1 IL1B IL18 IL12RB1 IFNGR1 IFNG
4
Show member pathways
13.15 TLR4 STAT1 JUN IL1B IL18 IFNGR1
5 12.87 STAT1 SPI1 JUN IL12RB1 IFNGR1 IFNG
6
Show member pathways
12.83 TLR4 STAT1 JUN IL1B IL18 IFNGR1
7
Show member pathways
12.78 TLR4 IL1B IL18 IFNG CASP1
8
Show member pathways
12.69 STAT1 JUN IL1B IFNGR1 IFNG
9
Show member pathways
12.66 JUN IL18 IL12RB1 IFNGR1 IFNG
10
Show member pathways
12.64 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
11
Show member pathways
12.62 STAT1 IL1B IL18 IL12RB1 IFNG
12
Show member pathways
12.57 TLR4 STAT1 JUN IL1B IL18 IL12RB1
13 12.43 TLR4 JUN IL1B IL18 CASP1
14
Show member pathways
12.38 SLC11A1 DEFB4A DEFB1 DEFA5 CCR6
15
Show member pathways
12.37 STAT1 IL12RB1 IFNGR1 IFNG
16
Show member pathways
12.35 JUN IL1B IFNG DEFB4A
17
Show member pathways
12.35 TLR4 STAT1 SPI1 JUN IL1B IFNGR1
18 12.34 TLR4 JUN IL1B IL18 CASP1
19
Show member pathways
12.3 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
20
Show member pathways
12.27 STAT1 JUN IL1B IL18 CP
21
Show member pathways
12.25 TLR4 STAT1 IL1B IFNGR1 IFNG CASP1
22
Show member pathways
12.24 STAT1 JUN IL1B CASP1
23 12.21 TLR4 STAT1 IFNGR1 IFNG
24 12.17 VDR TLR4 STAT1 IL1B IL18 IFNGR1
25 12.08 STAT1 SPI1 JUN IL1B IFNGR1 IFNG
26
Show member pathways
12.07 TLR4 STAT1 JUN IL1B
27 12.05 TLR4 JUN IL1B IL18 CASP1
28
Show member pathways
12.02 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
29 12.02 TLR4 STAT1 JUN IL1B IL18 DEFB4A
30
Show member pathways
12.01 STAT1 JUN IL1B IL18 IL12RB1 IFNG
31 11.93 STAT1 IL12RB1 IFNGR1 IFNG
32 11.92 TLR4 JUN IL1B IL18 IFNG
33
Show member pathways
11.87 STAT1 IL1B IFNGR1 IFNG CASP1
34 11.86 STAT1 SPI1 JUN IFNG
35 11.81 TLR4 JUN IL1B CASP1
36 11.77 SPI1 IL1B IFNG
37 11.74 IL1B IL18 IFNG
38 11.7 SPI1 IL1B IL18 IL12RB1 IFNG CCR6
39
Show member pathways
11.68 JUN IL1B IFNG
40 11.67 TLR4 IL1B IL18 CASP1
41 11.65 STAT1 JUN IFNG
42 11.61 TLR4 IL1B IL18 IFNG
43 11.58 TLR4 IL1B IL18 IFNG
44
Show member pathways
11.57 JUN IFNGR1 IFNG
45 11.55 JUN IL1B IFNG
46 11.54 VDR JUN IL1B IFNG
47 11.47 IL1B IL18 CASP1
48 11.42 IL1B IL18 IFNG
49 11.4 TLR4 JUN IL1B IL18 IFNGR1 IFNG
50 11.37 STAT1 SPI1 IL1B IFNGR1 IFNG

GO Terms for Salmonellosis

Cellular components related to Salmonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.28 IL1B IL18 IFNG GPT DEFB4A DEFB1

Biological processes related to Salmonellosis according to GeneCards Suite gene sharing:

(show all 41)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.27 VDR TLR4 STAT1 IL1B IL18 IL12RB1
2 positive regulation of transcription by RNA polymerase II GO:0045944 10.11 VDR TLR4 STAT1 SPI1 SLC11A1 JUN
3 defense response to bacterium GO:0042742 9.92 TLR4 SLC11A1 DEFB4A DEFB1 DEFA5
4 response to lipopolysaccharide GO:0032496 9.91 TLR4 SLC11A1 JUN IL1B
5 defense response GO:0006952 9.89 STAT1 DEFB4A DEFB1 DEFA5
6 positive regulation of inflammatory response GO:0050729 9.86 TLR4 IL1B IL18
7 cellular response to lipopolysaccharide GO:0071222 9.85 VDR TLR4 IL1B DEFA5 CASP1
8 cellular response to mechanical stimulus GO:0071260 9.84 TLR4 IL1B CASP1
9 interferon-gamma-mediated signaling pathway GO:0060333 9.83 STAT1 IFNGR1 IFNG
10 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.82 DEFB4A DEFB1 DEFA5
11 cellular response to organic cyclic compound GO:0071407 9.81 STAT1 IL1B IL18
12 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.81 TLR4 IL1B IL18
13 positive regulation of smooth muscle cell proliferation GO:0048661 9.8 STAT1 JUN IL18
14 cellular response to interferon-gamma GO:0071346 9.8 TLR4 STAT1 IL12RB1 CASP1
15 cytokine-mediated signaling pathway GO:0019221 9.8 STAT1 IL1B IL18 IL12RB1 IFNGR1 CASP1
16 positive regulation of gene expression GO:0010628 9.8 VDR TLR4 SLC11A1 IL1B IL18 IFNGR1
17 positive regulation of phagocytosis GO:0050766 9.77 SLC11A1 IL1B IFNG
18 positive regulation of nitric oxide biosynthetic process GO:0045429 9.76 TLR4 IL1B IFNG
19 positive regulation of epithelial cell migration GO:0010634 9.75 JUN IFNG CCR6
20 lipopolysaccharide-mediated signaling pathway GO:0031663 9.74 TLR4 IL1B IL18
21 microglial cell activation GO:0001774 9.71 JUN IFNGR1 IFNG
22 positive regulation of neuroinflammatory response GO:0150078 9.68 IL1B IL18
23 positive regulation of interferon-alpha production GO:0032727 9.68 TLR4 STAT1
24 positive regulation of chemokine biosynthetic process GO:0045080 9.68 IL1B IFNG
25 macrophage activation GO:0042116 9.67 TLR4 SLC11A1
26 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 9.67 IL1B IL18
27 antimicrobial humoral response GO:0019730 9.67 SLC11A1 DEFB4A DEFB1 DEFA5
28 negative regulation of amyloid-beta clearance GO:1900222 9.66 IFNGR1 IFNG
29 positive regulation of MHC class II biosynthetic process GO:0045348 9.66 TLR4 IFNG
30 T-helper 1 type immune response GO:0042088 9.65 TLR4 IL18
31 positive regulation of T-helper 1 type immune response GO:0002827 9.65 SLC11A1 IL12RB1
32 astrocyte activation GO:0048143 9.65 IL1B IFNGR1 IFNG
33 interleukin-6 production GO:0032635 9.62 IL1B IL18
34 positive regulation of T-helper 1 cell cytokine production GO:2000556 9.61 IL1B IL18
35 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.61 TLR4 STAT1 IFNG
36 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.58 STAT1 IFNGR1 IFNG
37 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.56 IL1B IFNG
38 immune response GO:0006955 9.56 TLR4 SLC11A1 IL1B IL18 IFNG DEFB4A
39 positive regulation of flagellated sperm motility involved in capacitation GO:0060474 9.55 DEFB1 CCR6
40 defense response to Gram-negative bacterium GO:0050829 9.55 TLR4 SLC11A1 DEFB4A DEFB1 DEFA5
41 positive regulation of interferon-gamma production GO:0032729 9.02 TLR4 SLC11A1 IL1B IL18 IL12RB1

Molecular functions related to Salmonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.17 TLR4 STAT1 LACTB JUN DEFB1 CASP1
2 CCR6 chemokine receptor binding GO:0031731 8.96 DEFB4A DEFB1

Sources for Salmonellosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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