MCID: SLM003
MIFTS: 54

Salmonellosis

Categories: Blood diseases, Immune diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Salmonellosis

MalaCards integrated aliases for Salmonellosis:

Name: Salmonellosis 12 74 3 15 71
Salmonella Infections 54 42 17 71
Salmonella Infection 12 3 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060859
ICD9CM 34 003.0
UMLS 71 C0036117 C2945607

Summaries for Salmonellosis

MedlinePlus : 42 Salmonella is the name of a group of bacteria. In the United States, it is a common cause of foodborne illness. Salmonella occurs in raw poultry, eggs, beef, and sometimes on unwashed fruit and vegetables. You also can get infected after handling pets, especially reptiles like snakes, turtles, and lizards. Symptoms include Fever Diarrhea Abdominal cramps Headache Possible nausea, vomiting, and loss of appetite Symptoms usually last 4-7 days. Your health care provider diagnoses the infection with a stool test. Most people get better without treatment. Infection can be more serious in older adults, infants, and people with chronic health problems. If Salmonella gets into the bloodstream, it can be serious. The usual treatment is antibiotics. Typhoid fever, a more serious disease caused by Salmonella, is not common in the United States. It frequently occurs in developing countries. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Salmonellosis, also known as salmonella infections, is related to immunodeficiency 27b and immunodeficiency 27a, and has symptoms including fever and pruritus. An important gene associated with Salmonellosis is IL12RB1 (Interleukin 12 Receptor Subunit Beta 1), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Vaccines and Amoxicillin have been mentioned in the context of this disorder. Affiliated tissues include liver, small intestine and colon, and related phenotypes are Increased viability and cardiovascular system

Disease Ontology : 12 A primary bacterial infectious disease caused by the bacteria of the genus Salmonella. It has sypmtoms diarrhea, fever, vomiting, and abdominal cramps 12 to 72 hours after infection. In most cases, the illness lasts four to seven days, and most people recover without treatment.

CDC : 3 Salmonella is a bacteria that makes people sick. It was discovered by an American scientist named Dr. Salmon, and has been known to cause illness for over 125 years. The illness people get from a Salmonella infection is called salmonellosis. Most people infected with Salmonella develop diarrhea, fever, and abdominal cramps between 12 and 72 hours after infection. The illness usually lasts 4 to 7 days, and most individuals recover without treatment. In some cases, diarrhea may be so severe that the patient needs to be hospitalized. In these patients, the Salmonella infection may spread from the intestines to the blood stream, and then to other body sites. In these cases, Salmonella can cause death unless the person is treated promptly with antibiotics. The elderly, infants, and those with impaired immune systems are more likely to have a severe illness1.

Wikipedia : 74 Salmonellosis is a symptomatic infection caused by bacteria of the Salmonella type. The most common... more...

Related Diseases for Salmonellosis

Diseases in the Salmonellosis family:

Rare Form of Salmonellosis

Diseases related to Salmonellosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 606)
# Related Disease Score Top Affiliating Genes
1 immunodeficiency 27b 32.4 STAT1 IL12RB1 IFNGR1
2 immunodeficiency 27a 32.1 STAT1 IFNGR1 IFNG
3 gastroenteritis 31.6 LACTB IL1B IFNG ALB
4 typhoid fever 31.6 TLR4 SPI1 SLC11A1 IL1B IFNGR1 IFNG
5 diarrhea 31.4 TLR4 IL1B IFNG GPT ALB
6 shigellosis 31.2 TLR4 IL1B IL18 CASP1 ALB
7 dysentery 31.2 IL1B GPT CCR6 ALB
8 schistosomiasis 31.0 IFNGR1 IFNG GPT ALB
9 brucellosis 30.9 TLR4 SLC11A1 IL18 IFNG
10 osteomyelitis 30.9 TLR4 STAT1 IL1B IFNGR1 IFNG CASP1
11 appendicitis 30.8 TLR4 IL1B IFNG ALB
12 listeriosis 30.8 IL1B IL18 CCR6
13 campylobacteriosis 30.8 VDR TLR4 STAT1 SLC11A1 JUN IL1B
14 peritonitis 30.8 TLR4 IL1B IL18 ALB
15 septic arthritis 30.7 TLR4 IFNG DEFB4A
16 cholecystitis 30.7 TLR4 GPT ALB
17 acute kidney failure 30.6 IL18 GPT ALB
18 reactive arthritis 30.6 TLR4 SLC11A1 IL1B IFNG CCR6
19 ulcerative colitis 30.6 TLR4 IL1B IFNG CCR6
20 allergic disease 30.6 TLR4 IL1B IL18 IL12RB1 IFNG CCR6
21 toxic shock syndrome 30.6 TLR4 IL1B IFNG
22 lung abscess 30.5 LACTB IL1B IFNG ALB
23 bronchopneumonia 30.5 TLR4 IL1B GPT ALB
24 histoplasmosis 30.5 STAT1 IL12RB1 IFNG CCR6
25 chronic kidney disease 30.5 VDR TLR4 IL1B IL18 ALB
26 plague 30.5 TLR4 IL1B CASP1 ALB
27 neutropenia 30.5 TLR4 IL1B IFNG GPT ALB
28 endocarditis 30.5 LACTB IFNG ALB
29 acquired immunodeficiency syndrome 30.5 IL1B IL15 IFNG CCR6 CASP1 ALB
30 splenic abscess 30.4 LACTB GPT ALB
31 erythema nodosum 30.4 VDR IL1B IFNG
32 intestinal perforation 30.4 TLR4 GPT ALB
33 measles 30.4 TLR4 STAT1 IL1B IFNG
34 helicobacter pylori infection 30.4 JUN IL1B IFNGR1
35 chronic granulomatous disease 30.3 SLC11A1 IL1B IL18 IFNG CASP1
36 spondylitis 30.3 IL1B IFNG CCR6
37 endophthalmitis 30.3 IL1B DEFB1 ALB
38 acute pancreatitis 30.3 TLR4 IL1B IL18 GPT CASP1
39 cellulitis 30.3 LACTB GPT DEFB4A CCR6 ALB
40 necrotizing fasciitis 30.3 IL1B IL18 ALB
41 urethritis 30.3 TLR4 IL1B DEFB4A DEFA5
42 clostridium difficile colitis 30.3 IL1B CCR6 ALB
43 gastritis 30.3 TLR4 IL1B DEFB4A DEFB1 DEFA5 CCR6
44 leptospirosis 30.3 IL1B IL18 IFNG
45 cryoglobulinemia 30.3 IL1B IFNG GPT
46 klebsiella pneumonia 30.3 TLR4 IL1B CCR6 ALB
47 myocarditis 30.3 TLR4 IL1B IL18 IL12RB1 IFNG
48 pyelonephritis 30.3 TLR4 IL1B IFNG GPT ALB
49 nocardiosis 30.3 LACTB IL12RB1 IFNG
50 viral hepatitis 30.3 TLR4 IL1B IFNG GPT ALB

Comorbidity relations with Salmonellosis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Salmonellosis:



Diseases related to Salmonellosis

Symptoms & Phenotypes for Salmonellosis

UMLS symptoms related to Salmonellosis:


fever, pruritus

GenomeRNAi Phenotypes related to Salmonellosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability GR00386-A-1 8.92 DEFB1 IL18 LACTB STAT1

MGI Mouse Phenotypes related to Salmonellosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.21 ALB CASP1 IFNG IFNGR1 IL15 IL18
2 hematopoietic system MP:0005397 10.21 CASP1 CCR6 IFNG IFNGR1 IL12RB1 IL15
3 homeostasis/metabolism MP:0005376 10.17 ALB CASP1 CCR6 IFNG IFNGR1 IL12RB1
4 immune system MP:0005387 10.13 ALB CASP1 CCR6 IFNG IFNGR1 IL12RB1
5 digestive/alimentary MP:0005381 10.06 ALB CASP1 IFNG IFNGR1 IL18 SLC11A1
6 integument MP:0010771 9.9 CASP1 IFNG IFNGR1 IL12RB1 IL18 IL1B
7 neoplasm MP:0002006 9.61 ALB CASP1 IFNG IFNGR1 IL1B SLC11A1
8 skeleton MP:0005390 9.32 GPT IFNG IFNGR1 IL12RB1 IL1B JUN

Drugs & Therapeutics for Salmonellosis

Drugs for Salmonellosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 3
2
Amoxicillin Approved, Vet_approved 26787-78-0 33613
3
Ceftriaxone Approved 73384-59-5 5479530 5361919
4
Ampicillin Approved, Vet_approved 69-53-4 6249
5
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
6
tannic acid Approved 1401-55-4
7 Anti-Infective Agents
8 Anti-Bacterial Agents
9 Calcium, Dietary
10
Calcium Nutraceutical 7440-70-2 271

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Immunogenicity and Safety of a Single Dose of SP093 Typhoid Vi Polysaccharide Vaccine Given in Japanese Subjects Completed NCT01608815 Phase 3
2 Interaction Between Non-typhoid Salmonella, Host Microbiota, and Immune System During Acute Infection and Remission Unknown status NCT03494101
3 The Potential Role of the Household Environment as the Reservoir for Invasive Salmonellosis in Children, Kisangani, DR Congo. Completed NCT03073707
4 NCCLS Interpretive Criteria for Salmonella Completed NCT00177658
5 Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients Completed NCT00002052 Ceftriaxone sodium;Ampicillin sodium;Amoxicillin trihydrate
6 IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres Completed NCT02689193
7 Effect on Pregnancy Outcomes, Infant Growth and Development of an Egg Intervention During Pregnancy in Indonesia Not yet recruiting NCT04694235
8 Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR Congo: a Cohort Study Not yet recruiting NCT04289688

Search NIH Clinical Center for Salmonellosis

Inferred drug relations via UMLS 71 / NDF-RT 51 :


Chloramphenicol sodium succinate

Genetic Tests for Salmonellosis

Anatomical Context for Salmonellosis

MalaCards organs/tissues related to Salmonellosis:

40
Liver, Small Intestine, Colon, Kidney, Breast, T Cells, Spleen

Publications for Salmonellosis

Articles related to Salmonellosis:

(show top 50) (show all 7070)
# Title Authors PMID Year
1
A 3-Year-Old With Fever and Abdominal Pain: Availability Bias in the Time of COVID-19. 42
33047983 2021
2
A Systematic Review on Antimicrobial Resistance among Salmonella Typhi Worldwide. 42
32996447 2020
3
Salmonella enteritis spondylitis of thoracic spine: a case report and review of the literature. 42
32767972 2020
4
Toll-like receptor 2 variants are associated with acute reactive arthritis. 61 54
18975326 2008
5
Antimicrobial therapy of salmonelloses--current state and perspectives. 61 54
16918048 2006
6
The protective role of interleukin-18 in Salmonella infection. 61 54
11964842 2001
7
Impairment of STAT activation by IL-12 in a patient with atypical mycobacterial and staphylococcal infections. 54 61
11034424 2000
8
Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients. 54 61
9603733 1998
9
Salmonella inactivation and sponge/microfiber mediated cross-contamination during papaya wash with chlorine or peracetic acid as sanitizer. 61
33397611 2021
10
Potentially probiotic or postbiotic pre-converted nitrite from celery produced by an axenic culture system with probiotic lacticaseibacilli strain. 61
33373850 2021
11
Characterization of a novel class 1 integron InSW39 and a novel transposon Tn5393k identified in an imipenem-nonsusceptible Salmonella Typhimurium strain in Sichuan, China. 61
33248418 2021
12
Retail fresh vegetables as a potential source of Salmonella infection in the Mekong Delta, Vietnam. 61
33493824 2021
13
Oral co-administration of bivalent protein r-BL with U-Omp19 elicits mucosal immune responses and reduces S. Typhimurium shedding in BALB/c mice. 61
33460704 2021
14
Bacteriophage as an alternative to prevent reptile-associated Salmonella transmission. 61
33455089 2021
15
Salmonella enterica Serovars Dublin and Enteritidis Comparative Proteomics Reveals Differential Expression of Proteins Involved in Stress Resistance, Virulence, and Anaerobic Metabolism. 61
33361201 2021
16
Whole-genome sequencing analysis and CRISPR genotyping of rare antibiotic-resistant Salmonella enterica serovars isolated from food and related sources. 61
32912589 2021
17
Active vitamin D3 attenuates the severity of Salmonella colitis in mice by orchestrating innate immunity. 61
33559391 2021
18
An unusual case of sepsis due to Salmonella enterica serovar Weltevreden, an emerging pathogen of non-typhoidal salmonellosis. 61
33530877 2021
19
Prevalence and antimicrobial resistance profiles of Salmonella species and Escherichia coli isolates from poultry feeds in Ruiru Sub-County, Kenya. 61
33526077 2021
20
Perspectives for the use of latex peptidases from Calotropis procera for control of inflammation derived from Salmonella infections. 61
33418044 2021
21
Repurposing of FDA approved drugs and their validation against potential drug targets for Salmonella enterica through molecular dynamics simulation. 61
33525976 2021
22
Causes of neonatal calf diarrhea and mortality in pasture-based dairy herds in Uruguay: a farm-matched case-control study. 61
33575990 2021
23
Effect of Feeding a Postbiotic Derived from Saccharomyces cerevisiae Fermentation as a Preharvest Food Safety Hurdle for Reducing Salmonella Enteritidis in the Ceca of Layer Pullets. 61
32977331 2021
24
Prevalence and antimicrobial susceptibility profiles of non-typhoidal Salmonella isolated from chickens in Rajshahi, Bangladesh. 61
33527778 2021
25
Rapid estimation of Salmonella enterica contamination level in ground beef - Application of the time-to-positivity method using a combination of molecular detection and direct plating. 61
32912587 2021
26
Antimicrobial Resistance and Molecular Characterization of Class 1 Integron in Salmonella Isolates Recovered from Pig Farms in Chongqing, China. 61
33493405 2021
27
Draft Genome Sequence of Salmonella enterica subsp. enterica Serovar Livingstone 1236H, a Desiccation-Resistant Strain That Poses a Salmonellosis Hazard in Low-Moisture Foods. 61
33414333 2021
28
Influence of air temperature and implemented veterinary measures on the incidence of human salmonellosis in the Czech Republic during 1998-2017. 61
33407314 2021
29
Impact of Salmonella Control Programmes in Poultry on Human Salmonellosis Burden in Greece. 61
33525354 2021
30
Non-typhoidal human salmonellosis in Rio Grande do Sul, Brazil: A combined source attribution study of microbial subtyping and outbreak data. 61
33285359 2021
31
Clinical features and risk factors associated with bacteremia of nontyphoidal salmonellosis in pediatric patients, 2010-2018. 61
32389417 2021
32
Salmonella Infection in Nursery Piglets and Its Role in the Spread of Salmonellosis to Further Production Periods. 61
33504097 2021
33
Human ABO Blood Groups and Their Associations with Different Diseases. 61
33564677 2021
34
Anti-IFN-γ Immunodeficiency Syndrome Presenting as Blurred Vision and Salmonellosis. 61
33155085 2021
35
Isolation and Identification of Salmonella in Pork. 61
32894498 2021
36
Diverse lineages of multidrug resistant clinical Salmonella enterica and a cryptic outbreak in New Hampshire, USA revealed from a year-long genomic surveillance. 61
33246085 2021
37
Prevalence, serovars and factors associated with Salmonella contamination of chicken carcasses sold in outlets of the  informal  market in Gauteng Province, South Africa. 61
33428739 2021
38
Integrated Whole-Genome Sequencing Infrastructure for Outbreak Detection and Source Tracing of Salmonella enterica Serotype Enteritidis. 61
33450161 2021
39
Infections in Patients with Chronic Granulomatous Disease Treated with Tumor Necrosis Factor Alpha Blockers for Inflammatory Complications. 61
33150502 2021
40
Frankliniella occidentalis facilitate Salmonella enterica survival in the phyllosphere. 61
33606799 2021
41
Resistance to colistin and production of extended-spectrum β-lactamases and/or AmpC enzymes in Salmonella isolates collected from healthy pigs in Northwest Spain in two periods: 2008-2009 and 2018. 61
33243630 2021
42
The Phylogenetic Structure of Reptile, Avian and Uropathogenic Escherichia coli with Particular Reference to Extraintestinal Pathotypes. 61
33530493 2021
43
Prevalence, Virulence and Antimicrobial Susceptibility of Salmonella spp., Yersinia enterocolitica and Listeria monocytogenes in European Wild Boar (Sus scrofa) Hunted in Tuscany (Central Italy). 61
33498307 2021
44
Food Safety Challenges in Refugee Camps: What do we know? 61
33411925 2021
45
Identification of Natural Mutations Responsible for Altered Infection Phenotypes of Salmonella enterica Clinical Isolates by Using Cell Line Infection Screens. 61
33127819 2021
46
Serotyping of sub-Saharan Africa Salmonella strains isolated from poultry feces using multiplex PCR and whole genome sequencing. 61
33468047 2021
47
Whole-Genome Sequencing Analysis of SalmonellaEnterica Serotype Enteritidis Isolated from Poultry Sources in South Korea, 2010-2017. 61
33430364 2021
48
Salmonella Prevalence Alone Is Not a Good Indicator of Poultry Food Safety. 61
32691435 2021
49
Inventory of biosecurity measures and antibiotics therapy practices on laying hen farms in Benin. 61
33487987 2020
50
Use of a Novel Sanitizer To Inactivate Salmonella Typhimurium and Spoilage Microorganisms during Flume Washing of Diced Tomatoes. 61
32692851 2020

Variations for Salmonellosis

Expression for Salmonellosis

Search GEO for disease gene expression data for Salmonellosis.

Pathways for Salmonellosis

Pathways related to Salmonellosis according to GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.02 TLR4 STAT1 SLC11A1 JUN IL1B IL18
2
Show member pathways
13.71 TLR4 JUN IL1B IL18 IL15 IL12RB1
3
Show member pathways
13.57 STAT1 JUN IL1B IL18 IL15 IL12RB1
4
Show member pathways
13.39 STAT1 IL1B IL18 IL15 IL12RB1 IFNGR1
5
Show member pathways
13.32 JUN IL1B IL18 IL15 IL12RB1 CCR6
6
Show member pathways
13.08 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
7 12.89 STAT1 SPI1 JUN IL15 IL12RB1 IFNGR1
8
Show member pathways
12.84 TLR4 STAT1 JUN IL1B IL18 IFNGR1
9
Show member pathways
12.77 TLR4 JUN IL1B IL18 CASP1
10
Show member pathways
12.76 TLR4 STAT1 JUN IL1B IL18 CASP1
11
Show member pathways
12.69 STAT1 JUN IL1B IFNGR1 IFNG
12
Show member pathways
12.66 JUN IL18 IL12RB1 IFNGR1 IFNG
13
Show member pathways
12.65 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
14
Show member pathways
12.62 STAT1 IL1B IL18 IL12RB1 IFNG
15
Show member pathways
12.57 TLR4 STAT1 JUN IL1B IL18 IL12RB1
16
Show member pathways
12.46 STAT1 IL15 IL12RB1 IFNGR1 IFNG
17 12.44 TLR4 JUN IL1B IL18 CASP1
18
Show member pathways
12.37 SLC11A1 DEFB4A DEFB1 DEFA5 CCR6
19
Show member pathways
12.36 JUN IL1B IFNG DEFB4A
20
Show member pathways
12.35 TLR4 STAT1 SPI1 JUN IL1B IFNGR1
21
Show member pathways
12.31 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
22
Show member pathways
12.3 STAT1 IL1B IL18 IL15 IFNG
23
Show member pathways
12.24 STAT1 JUN IL1B CASP1
24
Show member pathways
12.24 TLR4 STAT1 IL1B IFNGR1 IFNG CASP1
25 12.22 TLR4 STAT1 IFNGR1 IFNG
26 12.14 TLR4 JUN IL1B IL18 CASP1
27 12.12 VDR TLR4 STAT1 IL1B IL18 IFNGR1
28 12.08 STAT1 SPI1 JUN IL1B IFNGR1 IFNG
29
Show member pathways
12.07 TLR4 STAT1 JUN IL1B
30
Show member pathways
12.02 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
31 12.02 TLR4 STAT1 JUN IL1B IL18 DEFB4A
32
Show member pathways
12.01 STAT1 JUN IL1B IL18 IL12RB1 IFNG
33
Show member pathways
11.92 TLR4 STAT1 IL1B IL12RB1 IFNG
34
Show member pathways
11.87 STAT1 IL1B IFNGR1 IFNG CASP1
35 11.86 STAT1 IFNGR1 IFNG
36 11.85 STAT1 SPI1 JUN IFNG
37 11.81 TLR4 JUN IL1B CASP1
38 11.81 TLR4 JUN IL1B IL18 IL15 IFNG
39 11.77 SPI1 IL1B IFNG
40 11.72 TLR4 SPI1 CCR6
41
Show member pathways
11.69 JUN IL1B IFNG
42 11.68 TLR4 IL1B IL18 CASP1
43 11.65 STAT1 JUN IFNG
44 11.61 TLR4 IL1B IL18 IFNG
45
Show member pathways
11.59 JUN IFNGR1 IFNG
46 11.58 TLR4 IL1B IL18 IFNG
47 11.56 JUN IL1B IFNG
48 11.55 VDR JUN IL1B IFNG
49 11.48 IL1B IL18 CASP1
50 11.43 IL1B IL18 IFNG

GO Terms for Salmonellosis

Cellular components related to Salmonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 IL1B IL18 IL15 IFNG DEFB4A DEFB1
2 extracellular space GO:0005615 9.28 IL1B IL18 IL15 IFNG GPT DEFB4A

Biological processes related to Salmonellosis according to GeneCards Suite gene sharing:

(show all 44)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.27 TLR4 STAT1 IL1B IL18 IL15 IL12RB1
2 positive regulation of transcription by RNA polymerase II GO:0045944 10.19 VDR TLR4 STAT1 SPI1 SLC11A1 JUN
3 inflammatory response GO:0006954 10.03 TLR4 SLC11A1 IL1B IL18 IL15
4 defense response to bacterium GO:0042742 9.95 TLR4 SLC11A1 DEFB4A DEFB1 DEFA5
5 cellular response to lipopolysaccharide GO:0071222 9.91 TLR4 IL1B DEFA5 CASP1
6 positive regulation of gene expression GO:0010628 9.91 VDR TLR4 SLC11A1 IL1B IL18 IFNGR1
7 defense response GO:0006952 9.9 STAT1 DEFB4A DEFB1 DEFA5
8 response to lipopolysaccharide GO:0032496 9.89 TLR4 SLC11A1 JUN IL1B CASP1
9 cytokine-mediated signaling pathway GO:0019221 9.88 STAT1 IL1B IL18 IL12RB1 IFNGR1 CASP1
10 positive regulation of interleukin-6 production GO:0032755 9.87 TLR4 IL1B IFNG
11 positive regulation of tumor necrosis factor production GO:0032760 9.87 TLR4 IFNGR1 IFNG
12 response to bacterium GO:0009617 9.86 TLR4 SLC11A1 DEFB1 CASP1
13 cellular response to mechanical stimulus GO:0071260 9.85 TLR4 IL1B CASP1
14 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.85 DEFB4A DEFB1 DEFA5
15 interferon-gamma-mediated signaling pathway GO:0060333 9.84 STAT1 IFNGR1 IFNG
16 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.84 IL18 IL15 IFNG
17 cellular response to interferon-gamma GO:0071346 9.84 TLR4 STAT1 IL12RB1 CASP1
18 cellular response to organic cyclic compound GO:0071407 9.83 STAT1 IL1B IL18
19 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.83 TLR4 IL1B IL18
20 positive regulation of smooth muscle cell proliferation GO:0048661 9.82 STAT1 JUN IL18
21 positive regulation of interleukin-1 beta production GO:0032731 9.8 TLR4 IFNG CASP1
22 positive regulation of nitric oxide biosynthetic process GO:0045429 9.77 TLR4 IL1B IFNG
23 antimicrobial humoral response GO:0019730 9.76 SLC11A1 DEFB4A DEFB1 DEFA5
24 lipopolysaccharide-mediated signaling pathway GO:0031663 9.74 TLR4 IL1B IL18
25 positive regulation of cytokine production GO:0001819 9.73 SLC11A1 IL15 IFNG CASP1
26 macrophage differentiation GO:0030225 9.7 SPI1 IL15 IFNG
27 positive regulation of neuroinflammatory response GO:0150078 9.69 IL1B IL18
28 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.69 TLR4 STAT1 IFNG
29 negative regulation of amyloid-beta clearance GO:1900222 9.68 IFNGR1 IFNG
30 positive regulation of MHC class II biosynthetic process GO:0045348 9.68 TLR4 IFNG
31 positive regulation of T-helper 1 type immune response GO:0002827 9.68 SLC11A1 IL12RB1
32 T-helper 1 type immune response GO:0042088 9.67 TLR4 IL18
33 positive regulation of natural killer cell proliferation GO:0032819 9.65 IL18 IL15
34 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.65 STAT1 IFNGR1 IFNG
35 positive regulation of inflammatory response GO:0050729 9.65 TLR4 IL1B IL18 IL15 IFNG
36 interleukin-1 beta production GO:0032611 9.64 TLR4 CASP1
37 positive regulation of tissue remodeling GO:0034105 9.62 IL18 IL15
38 positive regulation of phagocytosis GO:0050766 9.62 SLC11A1 IL1B IL15 IFNG
39 positive regulation of T-helper 1 cell cytokine production GO:2000556 9.61 IL1B IL18
40 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.58 IL1B IFNG
41 positive regulation of flagellated sperm motility involved in capacitation GO:0060474 9.58 DEFB1 CCR6
42 defense response to Gram-negative bacterium GO:0050829 9.55 TLR4 SLC11A1 DEFB4A DEFB1 DEFA5
43 positive regulation of interferon-gamma production GO:0032729 9.35 TLR4 SLC11A1 IL1B IL18 IL12RB1
44 immune response GO:0006955 9.28 TLR4 SLC11A1 IL1B IL18 IL15 IFNG

Molecular functions related to Salmonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 IL1B IL18 IL15 IFNG
2 CCR6 chemokine receptor binding GO:0031731 8.62 DEFB4A DEFB1

Sources for Salmonellosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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