MCID: SLM003
MIFTS: 54

Salmonellosis

Categories: Blood diseases, Immune diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Salmonellosis

MalaCards integrated aliases for Salmonellosis:

Name: Salmonellosis 12 73 3 15 70
Salmonella Infections 54 42 17 70
Salmonella Infection 12 3 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060859
ICD9CM 34 003.0
UMLS 70 C0036117 C2945607

Summaries for Salmonellosis

MedlinePlus : 42 Salmonella is the name of a group of bacteria. In the United States, it is a common cause of foodborne illness. Salmonella occurs in raw poultry, eggs, beef, and sometimes on unwashed fruit and vegetables. You also can get infected after handling pets, especially reptiles like snakes, turtles, and lizards. Symptoms include Fever Diarrhea Abdominal cramps Headache Possible nausea, vomiting, and loss of appetite Symptoms usually last 4-7 days. Your health care provider diagnoses the infection with a stool test. Most people get better without treatment. Infection can be more serious in older adults, infants, and people with chronic health problems. If Salmonella gets into the bloodstream, it can be serious. The usual treatment is antibiotics. Typhoid fever, a more serious disease caused by Salmonella, is not common in the United States. It frequently occurs in developing countries. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Salmonellosis, also known as salmonella infections, is related to immunodeficiency 27b and immunodeficiency 27a, and has symptoms including fever and pruritus. An important gene associated with Salmonellosis is IL12RB1 (Interleukin 12 Receptor Subunit Beta 1), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Vaccines and Ceftriaxone have been mentioned in the context of this disorder. Affiliated tissues include liver, kidney and bone, and related phenotypes are Increased viability and cardiovascular system

Disease Ontology : 12 A primary bacterial infectious disease caused by the bacteria of the genus Salmonella. It has sypmtoms diarrhea, fever, vomiting, and abdominal cramps 12 to 72 hours after infection. In most cases, the illness lasts four to seven days, and most people recover without treatment.

CDC : 3 Salmonella is a bacteria that makes people sick. It was discovered by an American scientist named Dr. Salmon, and has been known to cause illness for over 125 years. The illness people get from a Salmonella infection is called salmonellosis. Most people infected with Salmonella develop diarrhea, fever, and abdominal cramps between 12 and 72 hours after infection. The illness usually lasts 4 to 7 days, and most individuals recover without treatment. In some cases, diarrhea may be so severe that the patient needs to be hospitalized. In these patients, the Salmonella infection may spread from the intestines to the blood stream, and then to other body sites. In these cases, Salmonella can cause death unless the person is treated promptly with antibiotics. The elderly, infants, and those with impaired immune systems are more likely to have a severe illness1.

Wikipedia : 73 Salmonellosis is a symptomatic infection caused by bacteria of the Salmonella type. The most common... more...

Related Diseases for Salmonellosis

Diseases in the Salmonellosis family:

Rare Form of Salmonellosis

Diseases related to Salmonellosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 616)
# Related Disease Score Top Affiliating Genes
1 immunodeficiency 27b 32.3 STAT1 IL12RB1 IFNGR1
2 immunodeficiency 27a 32.1 STAT1 IFNGR1 IFNG
3 typhoid fever 31.6 TLR4 SPI1 SLC11A1 IL1B IFNGR1 IFNG
4 gastroenteritis 31.6 LACTB IL1B IFNG ALB
5 diarrhea 31.4 TLR4 STAT1 IL1B IFNG GPT ALB
6 shigellosis 31.3 TLR4 IL1B IL18 CASP1 ALB
7 dysentery 31.2 IL1B GPT CCR6 ALB
8 schistosomiasis 31.0 IFNGR1 IFNG GPT ALB
9 brucellosis 30.9 TLR4 SLC11A1 IL18 IFNG
10 osteomyelitis 30.9 TLR4 STAT1 IL1B IFNGR1 IFNG CASP1
11 listeriosis 30.9 IL1B IL18 CCR6
12 peritonitis 30.9 TLR4 IL1B IL18 ALB
13 appendicitis 30.8 TLR4 IL1B IFNG ALB
14 campylobacteriosis 30.8 VDR TLR4 STAT1 SLC11A1 JUN IL1B
15 septic arthritis 30.7 TLR4 IFNG DEFB4A
16 cholecystitis 30.7 TLR4 GPT ALB
17 acute kidney failure 30.7 IL18 GPT ALB
18 reactive arthritis 30.6 TLR4 SLC11A1 IL1B IFNG CCR6
19 lung abscess 30.6 LACTB IFNG ALB
20 allergic disease 30.6 TLR4 IL1B IL18 IL12RB1 IFNG CCR6
21 meningoencephalitis 30.6 IL1B CCR6 ALB
22 ulcerative colitis 30.6 TLR4 IL1B IFNG CCR6
23 toxic shock syndrome 30.6 TLR4 IL1B IFNG
24 pericarditis 30.5 IL1B IFNG ALB
25 histoplasmosis 30.5 STAT1 IL12RB1 IFNG CCR6
26 bronchopneumonia 30.5 TLR4 IL1B GPT ALB
27 plague 30.5 TLR4 IL1B CASP1 ALB
28 acquired immunodeficiency syndrome 30.5 IL1B IL15 IFNG CCR6 CASP1 ALB
29 endocarditis 30.4 LACTB IFNG ALB
30 splenic abscess 30.4 LACTB GPT ALB
31 erythema nodosum 30.4 VDR IL1B IFNG
32 intestinal perforation 30.4 TLR4 GPT ALB
33 chronic granulomatous disease 30.4 SLC11A1 IL1B IL18 IFNG CASP1
34 measles 30.4 TLR4 STAT1 IL1B IFNG
35 helicobacter pylori infection 30.4 JUN IL1B IFNGR1
36 acute pancreatitis 30.3 TLR4 IL1B IL18 GPT CASP1
37 spondylitis 30.3 IL1B IFNG CCR6
38 cellulitis 30.3 LACTB GPT DEFB4A CCR6 ALB
39 endophthalmitis 30.3 IL1B DEFB1 ALB
40 gastritis 30.3 TLR4 IL1B DEFB4A DEFB1 DEFA5 CCR6
41 necrotizing fasciitis 30.3 IL1B IL18 ALB
42 clostridium difficile colitis 30.3 IL1B CCR6 ALB
43 klebsiella pneumonia 30.3 TLR4 IL1B CCR6 ALB
44 leptospirosis 30.3 IL1B IL18 IFNG
45 urethritis 30.3 TLR4 IL1B DEFB4A DEFA5
46 myocarditis 30.3 TLR4 IL1B IL18 IL12RB1 IFNG
47 cryoglobulinemia 30.3 IL1B IFNG GPT
48 pyelonephritis 30.3 TLR4 IL1B IFNG GPT ALB
49 aphthous stomatitis 30.3 TLR4 IL1B IL18 IFNG
50 viral hepatitis 30.3 TLR4 IL1B IFNG GPT ALB

Comorbidity relations with Salmonellosis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Salmonellosis:



Diseases related to Salmonellosis

Symptoms & Phenotypes for Salmonellosis

UMLS symptoms related to Salmonellosis:


fever; pruritus

GenomeRNAi Phenotypes related to Salmonellosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability GR00386-A-1 8.92 DEFB1 IL18 LACTB STAT1

MGI Mouse Phenotypes related to Salmonellosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.21 ALB CASP1 IFNG IFNGR1 IL15 IL18
2 hematopoietic system MP:0005397 10.21 CASP1 CCR6 IFNG IFNGR1 IL12RB1 IL15
3 homeostasis/metabolism MP:0005376 10.17 ALB CASP1 CCR6 IFNG IFNGR1 IL12RB1
4 immune system MP:0005387 10.13 ALB CASP1 CCR6 IFNG IFNGR1 IL12RB1
5 digestive/alimentary MP:0005381 10.06 ALB CASP1 IFNG IFNGR1 IL18 SLC11A1
6 integument MP:0010771 9.9 CASP1 IFNG IFNGR1 IL12RB1 IL18 IL1B
7 neoplasm MP:0002006 9.61 ALB CASP1 IFNG IFNGR1 IL1B SLC11A1
8 skeleton MP:0005390 9.32 GPT IFNG IFNGR1 IL12RB1 IL1B JUN

Drugs & Therapeutics for Salmonellosis

Drugs for Salmonellosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 3
2
Ceftriaxone Approved 73384-59-5 5479530 5361919
3
Amoxicillin Approved, Vet_approved 26787-78-0 33613
4
Ampicillin Approved, Vet_approved 69-53-4 6249
5
tannic acid Approved 1401-55-4
6
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
7 Anti-Bacterial Agents
8 Anti-Infective Agents
9 Calcium, Dietary
10
Calcium Nutraceutical 7440-70-2 271

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Immunogenicity and Safety of a Single Dose of SP093 Typhoid Vi Polysaccharide Vaccine Given in Japanese Subjects Completed NCT01608815 Phase 3
2 Interaction Between Non-typhoid Salmonella, Host Microbiota, and Immune System During Acute Infection and Remission Unknown status NCT03494101
3 The Potential Role of the Household Environment as the Reservoir for Invasive Salmonellosis in Children, Kisangani, DR Congo. Completed NCT03073707
4 NCCLS Interpretive Criteria for Salmonella Completed NCT00177658
5 Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients Completed NCT00002052 Ceftriaxone sodium;Ampicillin sodium;Amoxicillin trihydrate
6 IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres Completed NCT02689193
7 Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR Congo: a Cohort Study Recruiting NCT04289688
8 Effect on Pregnancy Outcomes, Infant Growth and Development of an Egg Intervention During Pregnancy in Indonesia Recruiting NCT04694235

Search NIH Clinical Center for Salmonellosis

Inferred drug relations via UMLS 70 / NDF-RT 51 :


Chloramphenicol sodium succinate

Genetic Tests for Salmonellosis

Anatomical Context for Salmonellosis

MalaCards organs/tissues related to Salmonellosis:

40
Liver, Kidney, Bone, Myeloid, Skin, Small Intestine, Colon

Publications for Salmonellosis

Articles related to Salmonellosis:

(show top 50) (show all 7114)
# Title Authors PMID Year
1
The human health burden of non-typhoidal Salmonella enterica and Vibrio parahaemolyticus foodborne gastroenteritis in Shanghai, east China. 42 61
33186379 2020
2
Characterization of Salmonella Isolates from Various Geographical Regions of the Caucasus and Their Susceptibility to Bacteriophages. 42
33321823 2020
3
Epidemiology of streptomycin resistant Salmonella from humans and animals in Ethiopia: A systematic review and meta-analysis. 42
33332438 2020
4
Toll-like receptor 2 variants are associated with acute reactive arthritis. 61 54
18975326 2008
5
Antimicrobial therapy of salmonelloses--current state and perspectives. 54 61
16918048 2006
6
The protective role of interleukin-18 in Salmonella infection. 61 54
11964842 2001
7
Impairment of STAT activation by IL-12 in a patient with atypical mycobacterial and staphylococcal infections. 54 61
11034424 2000
8
Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients. 61 54
9603733 1998
9
Salmonella inactivation and sponge/microfiber mediated cross-contamination during papaya wash with chlorine or peracetic acid as sanitizer. 61
33397611 2021
10
The Safety, Tolerability and Efficacy of Probiotic Bacteria for Equine Use. 61
33781424 2021
11
Potentially probiotic or postbiotic pre-converted nitrite from celery produced by an axenic culture system with probiotic lacticaseibacilli strain. 61
33373850 2021
12
One-step differential detection of Salmonella enterica serovar Typhi, serovar Paratyphi A and other Salmonella spp. by using a quadruplex real-time PCR assay. 61
33662480 2021
13
Multiresistant and blaCTX-M-14-Carrying Salmonella ser. Typhimurium Isolated During a Salmonellosis Outbreak in an Equine Hospital in Argentina. 61
33781422 2021
14
Bacteriophage as an alternative to prevent reptile-associated Salmonella transmission. 61
33455089 2021
15
Treatment and management of Salmonella prostatitis in a heartworm-positive intact male dog: a case report. 61
33785042 2021
16
Protection Conferred by Drinking Water Administration of a Nanoparticle-Based Vaccine against Salmonella Enteritidis in Hens. 61
33802556 2021
17
Mitracarpus frigidus (Rubiaceae) inhibits inflammatory and oxidative stress mediators in Salmonella sp. mouse infection. 61
33791804 2021
18
Salmonella spp. in Pet Reptiles in Portugal: Prevalence and Chlorhexidine Gluconate Antimicrobial Efficacy. 61
33808891 2021
19
Oral co-administration of bivalent protein r-BL with U-Omp19 elicits mucosal immune responses and reduces S. Typhimurium shedding in BALB/c mice. 61
33460704 2021
20
Acidification and extended storage at room temperature of mayonnaise reduce Salmonella Typhimurium virulence and viability. 61
33641984 2021
21
Small Indian Mongooses (Herpestes auropunctatus) Serve As Reservoirs of Bartonella henselae and Rickettsia felis Vectored by Ctenocephalides felis. 61
33646062 2021
22
In vitro invasiveness and antimicrobial resistance of Salmonella enterica subspecies isolated from wild and captive reptiles. 61
33655685 2021
23
Prevalence and Molecular Characterization of Salmonella Isolated from Broiler Farms at the Tolima Region-Colombia. 61
33807224 2021
24
Retail fresh vegetables as a potential source of Salmonella infection in the Mekong Delta, Vietnam. 61
33493824 2021
25
Integrative and Conjugative Element-Mediated Azithromycin Resistance in Multidrug-Resistant Salmonella enterica serovar Albany. 61
33685895 2021
26
Salmonella spp. prevalence and antimicrobial resistance in broiler chicken and turkey flocks in Canada from 2013 to 2018. 61
33780135 2021
27
Isolation, Characterization, and Application in Poultry Product of a Specific Salmonella Bacteriophage S55. 61
33710342 2021
28
Economic evaluation of whole genome sequencing for pathogen identification and surveillance - results of case studies in Europe and the Americas 2016 to 2019. 61
33663647 2021
29
Characterization of a novel class 1 integron InSW39 and a novel transposon Tn5393k identified in an imipenem-nonsusceptible Salmonella Typhimurium strain in Sichuan, China. 61
33248418 2021
30
Generation of TCRα-transduced T cells for adoptive transfer therapy of salmonellosis in mice. 61
33748782 2021
31
Advances in the development of Salmonella-based vaccine strategies for protection against Salmonellosis in humans. 61
33665941 2021
32
Paneth Cell Alertness to Pathogens Maintained by Vitamin D Receptors. 61
33217447 2021
33
The potential role of nontyphoidal salmonellosis in gastric cancer: a nationwide matched cohort study. 61
33130973 2021
34
A Significant Decrease in the Incidence of Shigellosis in Israel during COVID-19 Pandemic. 61
33809746 2021
35
Natural Antimicrobials Suitable for Combating Desiccation-Resistant Salmonella enterica in Milk Powder. 61
33670672 2021
36
Rapid estimation of Salmonella enterica contamination level in ground beef - Application of the time-to-positivity method using a combination of molecular detection and direct plating. 61
32912587 2021
37
Monoassociation of Preterm Germ-Free Piglets with Bifidobacterium animalis Subsp. lactis BB-12 and Its Impact on Infection with Salmonella Typhimurium. 61
33670419 2021
38
Effect of Feeding a Postbiotic Derived from Saccharomyces cerevisiae Fermentation as a Preharvest Food Safety Hurdle for Reducing Salmonella Enteritidis in the Ceca of Layer Pullets. 61
32977331 2021
39
Competitive Exclusion of Intra-Genus Salmonella in Neonatal Broilers. 61
33670039 2021
40
Causes of neonatal calf diarrhea and mortality in pasture-based dairy herds in Uruguay: a farm-matched case-control study. 61
33575990 2021
41
Salmonella enterica Serovars Dublin and Enteritidis Comparative Proteomics Reveals Differential Expression of Proteins Involved in Stress Resistance, Virulence, and Anaerobic Metabolism. 61
33361201 2021
42
Predictive Modeling for the Growth of Salmonella spp. in Liquid Egg White and Application of Scenario-Based Risk Estimation. 61
33669000 2021
43
Repurposing of FDA approved drugs and their validation against potential drug targets for Salmonella enterica through molecular dynamics simulation. 61
33525976 2021
44
Prevalence and antimicrobial susceptibility profiles of non-typhoidal Salmonella isolated from chickens in Rajshahi, Bangladesh. 61
33527778 2021
45
Whole-genome sequencing analysis and CRISPR genotyping of rare antibiotic-resistant Salmonella enterica serovars isolated from food and related sources. 61
32912589 2021
46
Prevalence and antimicrobial resistance profiles of Salmonella species and Escherichia coli isolates from poultry feeds in Ruiru Sub-County, Kenya. 61
33526077 2021
47
Perspectives for the use of latex peptidases from Calotropis procera for control of inflammation derived from Salmonella infections. 61
33418044 2021
48
The European Union One Health 2019 Zoonoses Report. 61
33680134 2021
49
Association between Salmonella infection and colon cancer: a nationwide registry-based cohort study. 61
33551005 2021
50
Active vitamin D3 attenuates the severity of Salmonella colitis in mice by orchestrating innate immunity. 61
33559391 2021

Variations for Salmonellosis

Expression for Salmonellosis

Search GEO for disease gene expression data for Salmonellosis.

Pathways for Salmonellosis

Pathways related to Salmonellosis according to GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14 TLR4 STAT1 SLC11A1 JUN IL1B IL18
2
Show member pathways
13.71 TLR4 JUN IL1B IL18 IL15 IL12RB1
3
Show member pathways
13.57 STAT1 JUN IL1B IL18 IL15 IL12RB1
4
Show member pathways
13.4 STAT1 IL1B IL18 IL15 IL12RB1 IFNGR1
5
Show member pathways
13.33 JUN IL1B IL18 IL15 IL12RB1 CCR6
6
Show member pathways
13.22 TLR4 STAT1 JUN IL1B IL18 IFNGR1
7 12.88 STAT1 SPI1 JUN IL15 IL12RB1 IFNGR1
8
Show member pathways
12.82 TLR4 STAT1 JUN IL1B IL18 IFNGR1
9
Show member pathways
12.81 TLR4 JUN IL1B IFNGR1 IFNG
10
Show member pathways
12.77 TLR4 JUN IL1B IL18 CASP1
11
Show member pathways
12.7 STAT1 SPI1 JUN IL1B IFNGR1 IFNG
12
Show member pathways
12.69 STAT1 JUN IL1B IFNGR1 IFNG
13
Show member pathways
12.67 JUN IL18 IL12RB1 IFNGR1 IFNG
14
Show member pathways
12.64 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
15
Show member pathways
12.62 STAT1 IL1B IL18 IL12RB1 IFNG
16
Show member pathways
12.57 TLR4 STAT1 JUN IL1B IL18 IL12RB1
17
Show member pathways
12.47 TLR4 JUN IL1B IL18 CASP1
18
Show member pathways
12.46 STAT1 IL15 IL12RB1 IFNGR1 IFNG
19 12.45 TLR4 JUN IL1B IL18 CASP1
20
Show member pathways
12.38 SLC11A1 DEFB4A DEFB1 DEFA5 CCR6
21
Show member pathways
12.36 JUN IL1B IFNG DEFB4A
22
Show member pathways
12.34 TLR4 STAT1 SPI1 JUN IL1B IFNGR1
23
Show member pathways
12.3 STAT1 IL1B IL18 IL15 IFNG
24
Show member pathways
12.3 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
25
Show member pathways
12.26 STAT1 JUN IL1B IL18
26
Show member pathways
12.25 STAT1 JUN IL1B CASP1
27
Show member pathways
12.23 TLR4 STAT1 IL1B IFNGR1 IFNG CASP1
28 12.22 TLR4 STAT1 IFNGR1 IFNG
29 12.13 TLR4 JUN IL1B IL18 CASP1
30 12.12 VDR TLR4 STAT1 IL1B IL18 IFNGR1
31
Show member pathways
12.08 TLR4 STAT1 JUN IL1B
32
Show member pathways
12.02 TLR4 STAT1 JUN IL1B IFNGR1 IFNG
33 12.02 TLR4 STAT1 JUN IL1B IL18 DEFB4A
34
Show member pathways
12.01 STAT1 JUN IL1B IL18 IL12RB1 IFNG
35
Show member pathways
11.91 TLR4 STAT1 IL1B IL12RB1 IFNG
36
Show member pathways
11.87 STAT1 IL1B IFNGR1 IFNG CASP1
37 11.85 STAT1 SPI1 JUN IFNG
38 11.81 TLR4 JUN IL1B CASP1
39 11.81 TLR4 JUN IL1B IL18 IL15 IFNG
40 11.77 SPI1 IL1B IFNG
41 11.72 TLR4 SPI1 CCR6
42
Show member pathways
11.69 JUN IL1B IFNG
43 11.67 TLR4 IL1B IL18 CASP1
44 11.65 STAT1 JUN IFNG
45 11.61 TLR4 IL1B IL18 IFNG
46
Show member pathways
11.59 JUN IFNGR1 IFNG
47 11.57 TLR4 IL1B IL18 IFNG
48 11.56 JUN IL1B IFNG
49 11.54 VDR JUN IL1B IFNG
50 11.48 IL1B IL18 CASP1

GO Terms for Salmonellosis

Cellular components related to Salmonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 IL1B IL18 IL15 IFNG DEFB4A DEFB1
2 extracellular space GO:0005615 9.28 IL1B IL18 IL15 IFNG GPT DEFB4A

Biological processes related to Salmonellosis according to GeneCards Suite gene sharing:

(show all 43)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.27 TLR4 STAT1 IL1B IL18 IL15 IL12RB1
2 positive regulation of transcription by RNA polymerase II GO:0045944 10.19 VDR TLR4 STAT1 SPI1 SLC11A1 JUN
3 inflammatory response GO:0006954 10.03 TLR4 SLC11A1 IL1B IL18 IL15
4 defense response to bacterium GO:0042742 9.95 TLR4 SLC11A1 DEFB4A DEFB1 DEFA5
5 cellular response to lipopolysaccharide GO:0071222 9.91 TLR4 IL1B DEFA5 CASP1
6 positive regulation of gene expression GO:0010628 9.91 VDR TLR4 SLC11A1 IL1B IL18 IFNGR1
7 defense response GO:0006952 9.9 STAT1 DEFB4A DEFB1 DEFA5
8 response to lipopolysaccharide GO:0032496 9.89 TLR4 SLC11A1 JUN IL1B CASP1
9 cytokine-mediated signaling pathway GO:0019221 9.88 STAT1 IL1B IL18 IL12RB1 IFNGR1 CASP1
10 positive regulation of tumor necrosis factor production GO:0032760 9.87 TLR4 IFNGR1 IFNG
11 response to bacterium GO:0009617 9.86 TLR4 SLC11A1 DEFB1 CASP1
12 cellular response to mechanical stimulus GO:0071260 9.85 TLR4 IL1B CASP1
13 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.85 DEFB4A DEFB1 DEFA5
14 interferon-gamma-mediated signaling pathway GO:0060333 9.84 STAT1 IFNGR1 IFNG
15 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.84 IL18 IL15 IFNG
16 cellular response to interferon-gamma GO:0071346 9.84 TLR4 STAT1 IL12RB1 CASP1
17 cellular response to organic cyclic compound GO:0071407 9.83 STAT1 IL1B IL18
18 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.83 TLR4 IL1B IL18
19 positive regulation of smooth muscle cell proliferation GO:0048661 9.82 STAT1 JUN IL18
20 positive regulation of interleukin-1 beta production GO:0032731 9.8 TLR4 IFNG CASP1
21 positive regulation of nitric oxide biosynthetic process GO:0045429 9.77 TLR4 IL1B IFNG
22 antimicrobial humoral response GO:0019730 9.76 SLC11A1 DEFB4A DEFB1 DEFA5
23 lipopolysaccharide-mediated signaling pathway GO:0031663 9.74 TLR4 IL1B IL18
24 positive regulation of cytokine production GO:0001819 9.73 SLC11A1 IL15 IFNG CASP1
25 macrophage differentiation GO:0030225 9.7 SPI1 IL15 IFNG
26 positive regulation of neuroinflammatory response GO:0150078 9.69 IL1B IL18
27 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.69 TLR4 STAT1 IFNG
28 negative regulation of amyloid-beta clearance GO:1900222 9.68 IFNGR1 IFNG
29 positive regulation of MHC class II biosynthetic process GO:0045348 9.68 TLR4 IFNG
30 positive regulation of T-helper 1 type immune response GO:0002827 9.68 SLC11A1 IL12RB1
31 T-helper 1 type immune response GO:0042088 9.67 TLR4 IL18
32 positive regulation of natural killer cell proliferation GO:0032819 9.65 IL18 IL15
33 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.65 STAT1 IFNGR1 IFNG
34 positive regulation of inflammatory response GO:0050729 9.65 TLR4 IL1B IL18 IL15 IFNG
35 interleukin-1 beta production GO:0032611 9.64 TLR4 CASP1
36 positive regulation of tissue remodeling GO:0034105 9.62 IL18 IL15
37 positive regulation of phagocytosis GO:0050766 9.62 SLC11A1 IL1B IL15 IFNG
38 positive regulation of T-helper 1 cell cytokine production GO:2000556 9.61 IL1B IL18
39 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.58 IL1B IFNG
40 positive regulation of flagellated sperm motility involved in capacitation GO:0060474 9.58 DEFB1 CCR6
41 defense response to Gram-negative bacterium GO:0050829 9.55 TLR4 SLC11A1 DEFB4A DEFB1 DEFA5
42 positive regulation of interferon-gamma production GO:0032729 9.35 TLR4 SLC11A1 IL1B IL18 IL12RB1
43 immune response GO:0006955 9.28 TLR4 SLC11A1 IL1B IL18 IL15 IFNG

Molecular functions related to Salmonellosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 IL1B IL18 IL15 IFNG
2 CCR6 chemokine receptor binding GO:0031731 8.62 DEFB4A DEFB1

Sources for Salmonellosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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