MCID: SLP003
MIFTS: 37

Salpingitis

Categories: Reproductive diseases

Aliases & Classifications for Salpingitis

MalaCards integrated aliases for Salpingitis:

Name: Salpingitis 12 54 43 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:5733
MeSH 43 D012488
NCIt 49 C26880
SNOMED-CT 67 88157006
ICD10 32 N70.91
UMLS 71 C0036130

Summaries for Salpingitis

Disease Ontology : 12 A fallopian tube disease that is characterized by inflammation of the fallopian tube.

MalaCards based summary : Salpingitis is related to salpingitis isthmica nodosa and chronic gonococcal salpingitis. An important gene associated with Salpingitis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), and among its related pathways/superpathways are Legionellosis and Malaria. The drugs Levofloxacin and Ofloxacin have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and uterus.

Wikipedia : 74 Salpingitis is an infection and inflammation in the Fallopian tubes. It is often used synonymously with... more...

Related Diseases for Salpingitis

Diseases in the Salpingitis family:

Acute Salpingitis Chronic Salpingitis

Diseases related to Salpingitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 328)
# Related Disease Score Top Affiliating Genes
1 salpingitis isthmica nodosa 33.9 MFN2 AMH
2 chronic gonococcal salpingitis 33.8 CEACAM3 CEACAM1
3 acute salpingitis 33.5 CEACAM3 CD40LG
4 chronic salpingitis 33.0 ODF3 MFN2 CEACAM3 CEACAM1
5 salpingo-oophoritis 32.7 MFN2 AMH
6 pyosalpinx 31.2 ODF3 MFN2 ENSG00000262202 CRP C1QTNF3
7 endometritis 31.1 TNF TLR2 SIGLEC5
8 chlamydia 30.9 TNF TLR2 HSPD1 CRP CD40LG
9 haemophilus influenzae 30.6 TNF TLR2
10 peritonitis 30.6 TNF TLR2 CRP
11 cervicitis 30.6 TLR2 NAT9 HSPD1 ESCO2
12 hemometra 30.5 MFN2 ENSG00000262202
13 inclusion conjunctivitis 30.5 NAT9 HSPD1 ESCO2 CD40LG
14 pelvic inflammatory disease 30.2 TLR2 NAT9 MFN2 HSPD1 ESCO2 CRP
15 miliary tuberculosis 30.0 TNF CRP CD40LG
16 exanthem 30.0 TNF CRP CD40LG
17 pericarditis 30.0 TNF CRP CD40LG
18 acute gonococcal endometritis 30.0 VDAC1 CEACAM1 CD40LG
19 vaginitis 29.9 TNF TLR2 SIGLEC5
20 mycobacterium tuberculosis 1 29.8 TNF TLR2 HSPD1 CRP
21 amebiasis 29.7 TNF TLR2 CD40LG
22 toxic shock syndrome 29.6 TNF TLR2 HSPD1 CRP CD40LG
23 candidiasis 29.5 TNF TLR2 CD40LG
24 acute cystitis 29.5 TNF TLR2 CRP CD40LG
25 viral hepatitis 29.4 TNF TLR2 CRP CD40LG
26 bacterial infectious disease 29.3 TNF TLR2 HSPD1 CRP CD40LG
27 chlamydia pneumonia 29.3 TNF TLR2 HSPD1 CRP CD40LG
28 fallopian tube disease 28.9 VDAC1 TNF TLR2 NAT9 MFN2 CRP
29 urethritis 28.6 VDAC1 TNF TLR2 NAT9 HSPD1 ESCO2
30 tuberculous salpingitis 12.4
31 acute gonococcal salpingitis 12.4
32 acute eustachian salpingitis 12.2
33 chronic eustachian salpingitis 12.2
34 chronic salpingo-oophoritis 11.9
35 otosalpingitis 11.8
36 acute salpingo-oophoritis 11.7
37 infertility 10.7
38 ectopic pregnancy 10.7
39 endometriosis 10.6
40 appendicitis 10.5
41 intestinal tuberculosis 10.4 TNF CRP
42 drug reaction with eosinophilia and systemic symptoms 10.4 TNF CRP
43 ross river fever 10.4 NAT9 CD40LG
44 orbital plasma cell granuloma 10.4 CRP CD40LG
45 granuloma inguinale 10.4 ODF3 NAT9 ESCO2
46 lymphogranuloma venereum 10.4 ODF3 NAT9 ESCO2
47 chronic orbital inflammation 10.4 CRP CD40LG
48 acute retinal necrosis syndrome 10.3 SIGLEC5 CD40LG
49 rheumatoid arthritis interstitial lung disease 10.3 TNF CRP
50 neuroretinitis 10.3 CRP CD40LG

Graphical network of the top 20 diseases related to Salpingitis:



Diseases related to Salpingitis

Symptoms & Phenotypes for Salpingitis

Drugs & Therapeutics for Salpingitis

Drugs for Salpingitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
2
Ofloxacin Approved Phase 4 82419-36-1 4583
3 Anti-Infective Agents Phase 4
4 Renal Agents Phase 4
5 Cytochrome P-450 Enzyme Inhibitors Phase 4
6 Topoisomerase Inhibitors Phase 4
7 Anti-Infective Agents, Urinary Phase 4
8 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
9 Anti-Bacterial Agents Phase 4
10
Menotropins Approved 9002-68-0, 61489-71-2 5360545
11
Ganirelix Approved 124904-93-4, 123246-29-7 25081094
12
Cetrorelix Approved, Investigational 120287-85-6 16129715 25074887
13
Deslorelin Investigational, Vet_approved 57773-65-6
14
Imidacloprid Vet_approved 105827-78-9 86418
15 Fertility Agents
16 Contraceptive Agents
17 Hormone Antagonists
18 Luteolytic Agents
19 Antineoplastic Agents, Hormonal
20 Triptorelin Pamoate
21 Hormones
22 Prolactin Release-Inhibiting Factors
23 Chorionic Gonadotropin
24 Anesthetics
25 Central Nervous System Depressants

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess the Efficacy and Safety of Morinidazole With Levofloxacin and Sequential of Levofloxacin in Women With Pelvic Inflammatory Disease Unknown status NCT03391440 Phase 4 morinidazole
2 Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Women With Infertility Problems Recruiting NCT04071574 Human Chorionic Gonadotropin (hCG);Gonadotropins;GNRH-A Triptorelin;GnRH antagonist
3 Feasibility of Balloon Dilation of the Eustachian Tubes for Dilatory Dysfunction Under Local Anesthesia Not yet recruiting NCT04055714

Search NIH Clinical Center for Salpingitis

Cochrane evidence based reviews: salpingitis

Genetic Tests for Salpingitis

Anatomical Context for Salpingitis

MalaCards organs/tissues related to Salpingitis:

40
Lung, Testes, Uterus, Ovary, Colon, Lymph Node, Bone

Publications for Salpingitis

Articles related to Salpingitis:

(show top 50) (show all 1454)
# Title Authors PMID Year
1
PID: clinical and laparoscopic aspects. 54 61
10818418 2000
2
Serological responses of patients with ectopic pregnancy to epitopes of the Chlamydia trachomatis 60 kDa heat shock protein. 54 61
9619577 1998
3
Antibodies to the chlamydial 60 kd heat-shock protein are associated with laparoscopically confirmed perihepatitis. 54 61
9125613 1997
4
Proliferative response to conserved epitopes of the Chlamydia trachomatis and human 60-kilodalton heat-shock proteins by lymphocytes from women with salpingitis. 54 61
7520213 1994
5
Etiology, epidemiology, pathology, and advances in diagnosis, vaccine development, and treatment of Gallibacterium anatis infection in poultry: a review. 61
31902298 2020
6
Peritoneal and upper genital tract tuberculosis. 61
31663322 2020
7
Chlamydia trachomatis and Anti-MUC1 Serology and Subsequent Risk of High-Grade Serous Ovarian Cancer: A Population-Based Case-Control Study in Northern Sweden. 61
31805519 2020
8
Fortuitous diagnosis of Trichomoniasis by PCR using panfungal primers. 61
31726227 2020
9
Molecular characterization of variant infectious bronchitis virus in China, 2019: Implications for control programmes. 61
31943814 2020
10
First Report of Isolation of Gallibacterium anatis from Layer Chickens in Morocco with Decrease in Laying Performance. 61
31865689 2019
11
Infectious potential of human derived uropathogenic Escherichia coli UTI89 in the reproductive tract of laying hens. 61
31767071 2019
12
Tubal cancer in a young woman camouflaged as bilateral salpingitis. 61
31791170 2019
13
Longitudinal Study on Causes of Mortality in Danish Broiler Breeders. 61
31967422 2019
14
Comparison and assessment of necropsy lesions in end-of-lay laying hens from different housing systems in Denmark. 61
31557304 2019
15
Role of Antisperm Antibodies in Infertility, Pregnancy, and Potential forContraceptive and Antifertility Vaccine Designs: Research Progress and Pioneering Vision. 61
31527552 2019
16
Xanthogranulomatous Salpingitis. 61
31433377 2019
17
Therapeutic effect of human umbilical cord mesenchymal stem cells on tubal factor infertility using a chronic salpingitis murine model. 61
31190174 2019
18
Salpingitis Impairs Bovine Tubal Function and Sperm-Oviduct Interaction. 61
31350463 2019
19
Benefits of second-look laparoscopy in the management of pelvic inflammatory disease. 61
30910760 2019
20
B cell activation factor (BAFF) induces inflammation in the human fallopian tube leading to tubal pregnancy. 61
31088412 2019
21
Risk Factors for Tinnitus in 37,692 Patients Followed in General Practices in Germany. 61
30870350 2019
22
Specific Chicken Egg Yolk Antibody Improves the Protective Response against Gallibacterium anatis Infection. 61
30559219 2019
23
[Infertility caused by salpingitis treated based on theory of kidney deficiency and blood stasis]. 61
30989970 2019
24
Sarcoidosis of the fallopian tube: A rare case study with confirmed Propionibacterium acnes infection. 61
30178596 2019
25
RETROSPECTIVE STUDY OF MORTALITY IN CAPTIVE STRUTHIONIFORMES IN A FRENCH ZOO (1974-2015). 61
30592921 2018
26
Appendicitis in non-typhoidal salmonella bacteraemia. 61
30364447 2018
27
Diagnostic performance of abdominal point of care ultrasound performed by an emergency physician in acute right iliac fossa pain. 61
30467798 2018
28
Adult bilateral idiopathic occlusion of foramina of Monro: is foraminoplasty really safe and effective? 61
30366894 2018
29
Data on the epidemiology and pathology of anatipestifer disease in Hungary (2010-2014). 61
30264612 2018
30
Autosomal Dominant Polycystic Kidney Disease and Pericardial Effusion. 61
30210723 2018
31
A G1-lineage H9N2 virus with oviduct tropism causes chronic pathological changes in the infundibulum and a long-lasting drop in egg production. 61
30157967 2018
32
An integrative investigation of the therapeutic mechanism of Ainsliaea fragrans Champ. in cervicitis using liquid chromatography tandem mass spectrometry based on a rat plasma metabolomics strategy. 61
29729635 2018
33
Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis. 61
29805512 2018
34
Virulence of Escherichia coli Isolates Obtained from Layer Chickens with Colibacillosis Associated with Pericarditis, Perihepatitis, and Salpingitis in Experimentally Infected Chicks and Embryonated Eggs. 61
29944397 2018
35
Histopathologic Features of Postablation Tubal Sterilization Syndrome. 61
29505424 2018
36
Isolation, characterization, and antibiotic sensitivity assessment of Gallibacterium anatis biovar haemolytica, from diseased Egyptian chicken flocks during the years 2013 and 2015. 61
29471426 2018
37
Vaccination with outer membrane vesicles and the fimbrial protein FlfA offers improved protection against lesions following challenge with Gallibacterium anatis. 61
29615242 2018
38
Fitz-Hugh-Curtis syndrome associated with tuberculous salpingitis and peritonitis: a case presentation and review of literature. 61
29558895 2018
39
Identification, differentiation and antibiotic susceptibility of Gallibacterium isolates from diseased poultry. 61
29441195 2018
40
[Characteristics of the reproductive health of female population in Ukraine]. 61
30737944 2018
41
Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice. 61
29624589 2018
42
Chlamydia trachomatis as the Cause of Infectious Infertility: Acute, Repetitive or Persistent Long-Term Infection? 61
27370345 2018
43
The impact of HSF on endometrium. 61
29489973 2017
44
Tracing GFP-labeled WJMSCs in vivo using a chronic salpingitis model: an animal experiment. 61
29191249 2017
45
Treatment evaluation of Wharton's jelly-derived mesenchymal stem cells using a chronic salpingitis model: an animal experiment. 61
29041961 2017
46
Streptococcus pyogenes: an unusual cause of salpingitis. Case report and review of the literature. 61
28283947 2017
47
Causes of Normal Mortality in Commercial Egg-Laying Chickens. 61
28957010 2017
48
An incidental finding of chronic salpingitis complications: Tubo-uterine fistula. 61
28976128 2017
49
Longitudinal study of transmission of Escherichia coli from broiler breeders to broilers. 61
28757012 2017
50
Assessment of health and welfare of Austrian laying hens at slaughter demonstrates influence of husbandry system and season. 61
28084805 2017

Variations for Salpingitis

Expression for Salpingitis

Search GEO for disease gene expression data for Salpingitis.

Pathways for Salpingitis

Pathways related to Salpingitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.89 TNF TLR2 HSPD1
2 10.5 TNF TLR2 CD40LG

GO Terms for Salpingitis

Biological processes related to Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-positive bacterium GO:0050830 9.58 TNF TLR2 CRP
2 positive regulation of interleukin-6 production GO:0032755 9.5 TNF TLR2 HSPD1
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.46 TNF TLR2 CD40LG AMH
4 negative regulation of lipid storage GO:0010888 9.37 TNF CRP
5 regulation of immunoglobulin secretion GO:0051023 9.26 TNF CD40LG
6 positive regulation of interleukin-12 production GO:0032735 9.13 TLR2 HSPD1 CD40LG
7 positive regulation of interleukin-10 production GO:0032733 8.8 TLR2 HSPD1 CD40LG

Sources for Salpingitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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