MCID: SLP003
MIFTS: 39

Salpingitis

Categories: Reproductive diseases

Aliases & Classifications for Salpingitis

MalaCards integrated aliases for Salpingitis:

Name: Salpingitis 12 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5733
ICD10 33 N70.91 N70.9
MeSH 44 D012488
NCIt 50 C26880
SNOMED-CT 68 88157006
UMLS 73 C0036130

Summaries for Salpingitis

Disease Ontology : 12 A fallopian tube disease that is characterized by inflammation of the fallopian tube.

MalaCards based summary : Salpingitis is related to chronic salpingitis and acute salpingitis. An important gene associated with Salpingitis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), and among its related pathways/superpathways are Legionellosis and Apoptosis-related network due to altered Notch3 in ovarian cancer. The drugs Isoniazid and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include uterus, lymph node and ovary, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : 76 Salpingitis is an infection and inflammation in the Fallopian tubes. It is often used synonymously with... more...

Related Diseases for Salpingitis

Diseases in the Salpingitis family:

Acute Salpingitis Chronic Salpingitis

Diseases related to Salpingitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 134)
# Related Disease Score Top Affiliating Genes
1 chronic salpingitis 33.5 OVGP1 TNF
2 acute salpingitis 33.4 OVGP1 TCOF1 TNF
3 fallopian tube disease 31.9 OVGP1 POC1A
4 chlamydia 30.8 CRP HSPD1 TNF
5 peritonitis 30.7 CRP TNF
6 pelvic inflammatory disease 30.4 CRP HSPD1
7 appendicitis 30.2 CRP TNF
8 tuberculous peritonitis 30.1 CRP TNF
9 inclusion conjunctivitis 30.0 OVGP1 TNF
10 pericarditis 29.7 CRP TNF
11 salpingitis isthmica nodosa 12.5
12 chronic gonococcal salpingitis 12.5
13 tuberculous salpingitis 12.2
14 acute gonococcal salpingitis 12.2
15 acute eustachian salpingitis 12.1
16 chronic eustachian salpingitis 12.1
17 otosalpingitis 11.8
18 chronic salpingo-oophoritis 11.5
19 salpingo-oophoritis 11.4
20 acute salpingo-oophoritis 11.4
21 infertility 10.5
22 endometritis 10.4
23 ectopic pregnancy 10.4
24 endometriosis 10.3
25 trachoma 10.1 HSPD1 TNF
26 haemophilus influenzae 10.1
27 testicular disease 10.1 HSPD1 TNF
28 mixed connective tissue disease 10.1 HSPD1 TNF
29 leprosy 3 10.1 HSPD1 TNF
30 geographic tongue 10.1 AKTIP TNF
31 pyosalpinx 10.1
32 mesenteric lymphadenitis 10.0 CRP HSPD1
33 endocardium disease 10.0 CRP HSPD1
34 sphenoid sinusitis 10.0 CRP TCOF1
35 leiomyoma, uterine 10.0
36 crohn's disease 10.0
37 leiomyoma 10.0
38 fallopian tube carcinoma 10.0
39 cervicitis 10.0
40 adenocarcinoma 10.0
41 endocervicitis 10.0
42 fitz-hugh-curtis syndrome 10.0
43 drug reaction with eosinophilia and systemic symptoms 10.0 CRP TNF
44 tenosynovitis 10.0 AKTIP CRP
45 burns 10.0 CRP TNF
46 melancholia 10.0 CRP TNF
47 tendinitis 10.0 AKTIP CRP
48 relapsing fever 10.0 CRP TNF
49 central nervous system vasculitis 10.0 CRP TNF
50 louse-borne relapsing fever 10.0 CRP TNF

Graphical network of the top 20 diseases related to Salpingitis:



Diseases related to Salpingitis

Symptoms & Phenotypes for Salpingitis

GenomeRNAi Phenotypes related to Salpingitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.23 AKTIP ESPL1 TCOF1 TNF
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.23 AKTIP ESPL1 TCOF1 TNF

MGI Mouse Phenotypes related to Salpingitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 reproductive system MP:0005389 9.02 ESPL1 HSPD1 OVGP1 POC1A TNF

Drugs & Therapeutics for Salpingitis

Drugs for Salpingitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Isoniazid Approved, Investigational Phase 3 54-85-3 3767
2 Anti-Bacterial Agents Phase 3
3 Lipid Regulating Agents Phase 3
4 Anti-Infective Agents Phase 3
5 Antimetabolites Phase 3
6 Hypolipidemic Agents Phase 3
7 Antitubercular Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO) Completed NCT00495651 Phase 3 Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis;Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis
2 Pilot Study of Short Term Aspirin on the Biologic and Immunologic Changes of the Fallopian Tube Not yet recruiting NCT03771651 Early Phase 1 Aspirin 81 mg

Search NIH Clinical Center for Salpingitis

Cochrane evidence based reviews: salpingitis

Genetic Tests for Salpingitis

Anatomical Context for Salpingitis

MalaCards organs/tissues related to Salpingitis:

41
Uterus, Lymph Node, Ovary, Bone, Heart, Tongue, Pancreas

Publications for Salpingitis

Articles related to Salpingitis:

(show top 50) (show all 478)
# Title Authors Year
1
Virulence of Escherichia coli Isolates Obtained from Layer Chickens with Colibacillosis Associated with Pericarditis, Perihepatitis, and Salpingitis in Experimentally Infected Chicks and Embryonated Eggs. ( 29944397 )
2018
2
Fitz-Hugh-Curtis syndrome associated with tuberculous salpingitis and peritonitis: a case presentation and review of literature. ( 29558895 )
2018
3
Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis. ( 29805512 )
2018
4
Streptococcus pyogenes: an unusual cause of salpingitis. Case report and review of the literature. ( 28283947 )
2017
5
Pelvic inflammatory disease and salpingitis: incidence of primary and repeat episodes in England. ( 27678278 )
2017
6
Tracing GFP-labeled WJMSCs in vivo using a chronic salpingitis model: an animal experiment. ( 29191249 )
2017
7
Treatment evaluation of Wharton's jelly-derived mesenchymal stem cells using a chronic salpingitis model: an animal experiment. ( 29041961 )
2017
8
An incidental finding of chronic salpingitis complications: Tubo-uterine fistula. ( 28976128 )
2017
9
A rare case of tuberculous salpingitis. ( 28203396 )
2016
10
Congenital Tuberculosis after in-vitro Fertilization in a Woman Previously Undiagnosed with Tuberculosis Salpingitis. ( 27234420 )
2016
11
Experimental induced avian E. coli salpingitis: Significant impact of strain and host factors on the clinical and pathological outcome. ( 27139030 )
2016
12
Pathology and Molecular Characterization of Escherichia Coli Associated With the Avian Salpingitis-Peritonitis Disease Syndrome. ( 26953937 )
2016
13
An odyssey through salpingitis isthmica nodosa. ( 25463639 )
2015
14
Acute Salpingitis in a Nonsexually Active Adolescent. ( 26626893 )
2015
15
Pseudoxanthomatous salpingitis as an ex vivo model of fallopian tube serous carcinogenesis: a clinicopathologic study of 49 cases. ( 25760905 )
2015
16
Isolated Tubal Torsion in Patient With Chronic Salpingitis: A Challenging Diagnosis. ( 27678759 )
2015
17
Recurrent Pelvic Infections and Salpingitis after Perforated Appendicitis. ( 26342348 )
2015
18
Therapeutic influence of intraperitoneal injection of Wharton's jelly-derived mesenchymal stem cells on oviduct function and fertility in rats with acute and chronic salpingitis. ( 25966129 )
2015
19
Untreated chronic tuberculous salpingitis followed by successful in vitro fertilization conception and congenital tuberculosis. ( 25638787 )
2015
20
Ultrastructure damage of oviduct telocytes in rat model of acute salpingitis. ( 25753567 )
2015
21
Occurrence of weak mutators among avian pathogenic Escherichia coli (APEC) isolates causing salpingitis and peritonitis in broiler breeders. ( 24230977 )
2014
22
Incidental FDG uptake in bilateral salpingitis due to Morgagni cyst hydatids on PET/CT scan in a patient with solitary pulmonary nodule. ( 24866052 )
2014
23
Salpingitis isthmica nodosa and recurrent ectopic pregnancy. ( 25093466 )
2014
24
Recurrent pyometra and xanthogranulomatous salpingitis: A rare pathologic association in a postmenopausal lady. ( 25317003 )
2014
25
Enterobius vermicularis salpingitis seen in the setting of ectopic pregnancy in a Malaysian patient. ( 24989613 )
2014
26
Genetic diversity and virulence profiles of Escherichia coli causing salpingitis and peritonitis in broiler breeders. ( 23201240 )
2013
27
Ultrasound for diagnosing acute salpingitis: a prospective observational diagnostic study. ( 23503942 )
2013
28
Salpingitis isthmica nodosa: a case report. ( 24392408 )
2013
29
Histopathological features of an incidental case of cytomegalovirus salpingitis in a patient with inflammatory bowel disease. ( 23901687 )
2013
30
Tuberculous salpingitis: a case report. ( 23905137 )
2013
31
Xanthogranulomatous salpingitis and oophoritis associated with endometriosis and uterine leiomyoma presenting as intestinal obstruction. ( 22568924 )
2012
32
"Tubal ostium sunshine": hysteroscopic sign of chronic salpingitis. ( 23084667 )
2012
33
Xanthogranulomatous salpingitis with enterobial appendicitis. ( 21281012 )
2011
34
Endometrial histopathology in patients with laparoscopic proven salpingitis and HIV-1 infection. ( 21941427 )
2011
35
Xanthogranulomatous salpingitis as a rare pathologic aspect of chronic active pelvic inflammatory disease. ( 21393899 )
2011
36
Endometriosis with salpingitis simulating acute appendicitis. ( 27365797 )
2011
37
Formation of Fitz-Hugh Curtis adhesions due to perihepatitis associated with salpingitis. ( 20569533 )
2010
38
Xanthogranulomatous salpingitis associated with a large uterine leiomyoma. ( 20981281 )
2010
39
Histologically proven isoniazid hepatoxicity in complicated tuberculous salpingitis. ( 19723821 )
2009
40
Salpingitis isthmica nodosa. ( 19679986 )
2009
41
Salpingitis in geese associated with Mycoplasma sp. strain 1220. ( 19468942 )
2009
42
Xanthogranulomatous salpingitis: report of three cases and comparison with a case of pseudoxanthomatous salpingitis. ( 19205448 )
2008
43
Salpingitis. A rare cause of acute abdomen in a sexually inactive girl: a case report. ( 19017411 )
2008
44
Xanthogranulomatous salpingitis associated with fallopian tube mucosal endometriosis: a clue to the pathogenesis. ( 17349571 )
2007
45
Effect of human immunodeficiency virus-1 infection on treatment outcome of acute salpingitis. ( 16582116 )
2006
46
Acute peritonitis and salpingitis associated with streptococcal toxic shock syndrome caused by Lancefield group G alpha-haemolytic Streptococcus dysgalactiae subsp. equisimilis. ( 16772425 )
2006
47
A unique case of descending salpingitis and functioning endometrium in a MA1llerian remnant in a woman with Mayer-Rokitansky-KA1ster-Hauser syndrome. ( 15866600 )
2005
48
Observations on salpingitis, peritonitis and salpingoperitonitis in a layer breeder flock. ( 16272543 )
2005
49
Detection of Mycoplasma genitalium in women with laparoscopically diagnosed acute salpingitis. ( 16326847 )
2005
50
Microlaparoscopy and a GnRH agonist: a combined minimally invasive approach for the diagnosis and treatment of occlusive salpingitis isthmica nodosa associated with endometriosis. ( 16381361 )
2005

Variations for Salpingitis

Expression for Salpingitis

Search GEO for disease gene expression data for Salpingitis.

Pathways for Salpingitis

Pathways related to Salpingitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.9 HSPD1 TNF
3 9.9 CRP TNF

GO Terms for Salpingitis

Biological processes related to Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to glucocorticoid GO:0051384 9.26 HSPD1 TNF
2 positive regulation of interleukin-6 production GO:0032755 9.16 HSPD1 TNF
3 positive regulation of interferon-gamma production GO:0032729 8.96 HSPD1 TNF
4 negative regulation of lipid storage GO:0010888 8.62 CRP TNF

Sources for Salpingitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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