MCID: SLP003
MIFTS: 38

Salpingitis

Categories: Reproductive diseases

Aliases & Classifications for Salpingitis

MalaCards integrated aliases for Salpingitis:

Name: Salpingitis 12 54 43 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:5733
MeSH 43 D012488
NCIt 49 C26880
SNOMED-CT 67 88157006
ICD10 32 N70.91
UMLS 71 C0036130

Summaries for Salpingitis

Disease Ontology : 12 A fallopian tube disease that is characterized by inflammation of the fallopian tube.

MalaCards based summary : Salpingitis is related to chronic salpingitis and salpingo-oophoritis. An important gene associated with Salpingitis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), and among its related pathways/superpathways are Legionellosis and Malaria. The drugs Levofloxacin and Ofloxacin have been mentioned in the context of this disorder. Affiliated tissues include testes, uterus and ovary.

Wikipedia : 74 Salpingitis is an infection and inflammation in the Fallopian tubes (salpinges). It is often used... more...

Related Diseases for Salpingitis

Diseases in the Salpingitis family:

Acute Salpingitis Chronic Salpingitis

Diseases related to Salpingitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 435)
# Related Disease Score Top Affiliating Genes
1 chronic salpingitis 34.1 TNF ODF3 MFN2
2 salpingo-oophoritis 33.0 MFN2 AMH
3 pyosalpinx 31.4 ODF3 MFN2 ENSG00000262202 CRP C1QTNF3
4 endometritis 30.9 TNF TLR2 SIGLEC5
5 inclusion conjunctivitis 30.8 NAT9 HSPD1 CD40LG
6 chlamydia 30.7 TNF TLR2 HSPD1 CRP CD40LG
7 hemometra 30.6 MFN2 ENSG00000262202
8 haemophilus influenzae 30.4 TNF TLR2
9 vaginal discharge 30.3 TNF CRP CD40LG CD4
10 acute gonococcal endometritis 30.1 VDAC1 CEACAM1 CD40LG
11 miliary tuberculosis 29.7 TNF CRP CD40LG CD4
12 syphilis 29.7 TNF CRP CD40LG CD4
13 exanthem 29.7 TNF CRP CD40LG CD4
14 pericarditis 29.7 TNF CRP CD40LG CD4
15 cervicitis 29.7 TNF TLR2 NAT9 HSPD1 CD4
16 pelvic inflammatory disease 29.5 TLR2 SIGLEC5 NAT9 MFN2 HSPD1 CRP
17 toxic shock syndrome 29.5 TNF TLR2 HSPD1 CRP CD40LG
18 crohn's disease 29.5 TNF TLR2 CRP CD4
19 vaginitis 29.4 TNF TLR2 CD4
20 genital herpes 29.4 TLR2 CD40LG CD4
21 viral hepatitis 29.3 TNF TLR2 CRP CD40LG
22 mycobacterium tuberculosis 1 29.2 TNF TLR2 HSPD1 CRP CD4
23 fallopian tube disease 29.1 VDAC1 TNF TLR2 SIGLEC5 NAT9 MFN2
24 amebiasis 29.1 TNF TLR2 CD40LG CD4
25 acute cystitis 28.8 TNF TLR2 CRP CD40LG CD4
26 eye disease 28.7 TNF TLR2 CRP CD40LG CD4
27 chlamydia pneumonia 28.6 TNF TLR2 HSPD1 CRP CD40LG CD4
28 bacterial infectious disease 28.6 TNF TLR2 HSPD1 CRP CD40LG CD4
29 urethritis 28.4 VDAC1 TNF TLR2 NAT9 HSPD1 CRP
30 salpingitis isthmica nodosa 12.6
31 chronic gonococcal salpingitis 12.6
32 acute salpingitis 12.4
33 tuberculous salpingitis 12.4
34 acute gonococcal salpingitis 12.4
35 acute eustachian salpingitis 12.2
36 chronic eustachian salpingitis 12.2
37 chronic salpingo-oophoritis 11.9
38 otosalpingitis 11.8
39 acute salpingo-oophoritis 11.7
40 infertility 10.7
41 peritonitis 10.7
42 ectopic pregnancy 10.7
43 endometriosis 10.6
44 appendicitis 10.5
45 urogenital tuberculosis 10.5 MFN2 CRP
46 drug reaction with eosinophilia and systemic symptoms 10.5 TNF CRP
47 posterior scleritis 10.4 TNF CRP
48 japanese spotted fever 10.4 CRP CD40LG
49 ross river fever 10.4 NAT9 CD40LG
50 chronic orbital inflammation 10.4 CRP CD40LG

Graphical network of the top 20 diseases related to Salpingitis:



Diseases related to Salpingitis

Symptoms & Phenotypes for Salpingitis

Drugs & Therapeutics for Salpingitis

Drugs for Salpingitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
2
Ofloxacin Approved Phase 4 82419-36-1 4583
3
Lidocaine Approved, Vet_approved 137-58-6 3676
4
Cetrorelix Approved, Investigational 120287-85-6 16129715 25074887
5
Ganirelix Approved 123246-29-7, 124904-93-4 25081094
6
Menotropins Approved 61489-71-2, 9002-68-0 5360545
7
Imidacloprid Vet_approved 105827-78-9 86418
8 Sodium Channel Blockers
9 Analgesics
10 Anti-Arrhythmia Agents
11 Anesthetics, Local
12 Diuretics, Potassium Sparing
13 Hormone Antagonists
14 Hormones
15 Antineoplastic Agents, Hormonal
16 Prolactin Release-Inhibiting Factors
17 Contraceptive Agents
18 Chorionic Gonadotropin
19 Triptorelin Pamoate
20 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess the Efficacy and Safety of Morinidazole With Levofloxacin and Sequential of Levofloxacin in Women With Pelvic Inflammatory Disease Unknown status NCT03391440 Phase 4 morinidazole
2 Analgesic Efficacy of Intrauterine Lidocaine Flushing in Hysterosalpingo-foam Sonography: A Double-blind Randomized Controlled Trial Recruiting NCT04433611 2% lidocaine;0.9 % normal saline
3 Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Women With Infertility Problems Recruiting NCT04071574 Human Chorionic Gonadotropin (hCG);Gonadotropins;GNRH-A Triptorelin;GnRH antagonist
4 Feasibility of Balloon Dilation of the Eustachian Tubes for Dilatory Dysfunction Under Local Anesthesia Not yet recruiting NCT04055714

Search NIH Clinical Center for Salpingitis

Cochrane evidence based reviews: salpingitis

Genetic Tests for Salpingitis

Anatomical Context for Salpingitis

MalaCards organs/tissues related to Salpingitis:

40
Testes, Uterus, Ovary, Cervix, Colon, Lymph Node, Kidney

Publications for Salpingitis

Articles related to Salpingitis:

(show top 50) (show all 1463)
# Title Authors PMID Year
1
PID: clinical and laparoscopic aspects. 61 54
10818418 2000
2
Serological responses of patients with ectopic pregnancy to epitopes of the Chlamydia trachomatis 60 kDa heat shock protein. 54 61
9619577 1998
3
Antibodies to the chlamydial 60 kd heat-shock protein are associated with laparoscopically confirmed perihepatitis. 54 61
9125613 1997
4
Proliferative response to conserved epitopes of the Chlamydia trachomatis and human 60-kilodalton heat-shock proteins by lymphocytes from women with salpingitis. 61 54
7520213 1994
5
Etiology, epidemiology, pathology, and advances in diagnosis, vaccine development, and treatment of Gallibacterium anatis infection in poultry: a review. 61
31902298 2020
6
Effects of three abnormal conditions of fallopian tube on outcomes of the in vitro fertilization and embryo transfer technique. 61
32500588 2020
7
ACR Appropriateness Criteria® Female Infertility. 61
32370955 2020
8
Molecular characterization of variant infectious bronchitis virus in China, 2019: Implications for control programmes. 61
31943814 2020
9
Whole genome sequence comparison of avian pathogenic Escherichia coli from acute and chronic salpingitis of egg laying hens. 61
32434525 2020
10
[Gynecological Lemierre's syndrome: A case report and literature review]. 61
32371121 2020
11
Reproductive tract diseases in female backyard chickens (Gallus gallus domesticus) - diagnostic imaging and final outcome during a decade. 61
32325525 2020
12
An unusual case of fulminant generalized peritonitis secondary to purulent salpingitis caused by Prevotella bivia - case report with literature review. 61
32274360 2020
13
Adrenomedullin insufficiency alters macrophage activities in fallopian tube: a pathophysiologic explanation of tubal ectopic pregnancy. 61
32203061 2020
14
Neisseria gonorrhoeae-induced salpingitis is targeted by circular RNA EIF3K via miR-139-5p and regulating MAPK/NF-κB signaling pathway to promotes apoptosis and autophagy bacterial cells. 61
32045642 2020
15
Peritoneal and upper genital tract tuberculosis. 61
31663322 2020
16
Chlamydia trachomatis and Anti-MUC1 Serology and Subsequent Risk of High-Grade Serous Ovarian Cancer: A Population-Based Case-Control Study in Northern Sweden. 61
31805519 2020
17
Comparison and assessment of necropsy lesions in end-of-lay laying hens from different housing systems in Denmark. 61
32416793 2020
18
Fortuitous diagnosis of Trichomoniasis by PCR using panfungal primers. 61
31726227 2020
19
Infectious potential of human derived uropathogenic Escherichia coli UTI89 in the reproductive tract of laying hens. 61
31767071 2019
20
Tubal cancer in a young woman camouflaged as bilateral salpingitis. 61
31791170 2019
21
First Report of Isolation of Gallibacterium anatis from Layer Chickens in Morocco with Decrease in Laying Performance. 61
31865689 2019
22
Longitudinal Study on Causes of Mortality in Danish Broiler Breeders. 61
31967422 2019
23
Comparison and assessment of necropsy lesions in end-of-lay laying hens from different housing systems in Denmark. 61
31557304 2019
24
Role of Antisperm Antibodies in Infertility, Pregnancy, and Potential forContraceptive and Antifertility Vaccine Designs: Research Progress and Pioneering Vision. 61
31527552 2019
25
Xanthogranulomatous Salpingitis. 61
31433377 2019
26
Therapeutic effect of human umbilical cord mesenchymal stem cells on tubal factor infertility using a chronic salpingitis murine model. 61
31190174 2019
27
Salpingitis Impairs Bovine Tubal Function and Sperm-Oviduct Interaction. 61
31350463 2019
28
Benefits of second-look laparoscopy in the management of pelvic inflammatory disease. 61
30910760 2019
29
B cell activation factor (BAFF) induces inflammation in the human fallopian tube leading to tubal pregnancy. 61
31088412 2019
30
Risk Factors for Tinnitus in 37,692 Patients Followed in General Practices in Germany. 61
30870350 2019
31
Specific Chicken Egg Yolk Antibody Improves the Protective Response against Gallibacterium anatis Infection. 61
30559219 2019
32
[Infertility caused by salpingitis treated based on theory of kidney deficiency and blood stasis]. 61
30989970 2019
33
Sarcoidosis of the fallopian tube: A rare case study with confirmed Propionibacterium acnes infection. 61
30178596 2019
34
RETROSPECTIVE STUDY OF MORTALITY IN CAPTIVE STRUTHIONIFORMES IN A FRENCH ZOO (1974-2015). 61
30592921 2018
35
Appendicitis in non-typhoidal salmonella bacteraemia. 61
30364447 2018
36
Diagnostic performance of abdominal point of care ultrasound performed by an emergency physician in acute right iliac fossa pain. 61
30467798 2018
37
Adult bilateral idiopathic occlusion of foramina of Monro: is foraminoplasty really safe and effective? 61
30366894 2018
38
Data on the epidemiology and pathology of anatipestifer disease in Hungary (2010-2014). 61
30264612 2018
39
Autosomal Dominant Polycystic Kidney Disease and Pericardial Effusion. 61
30210723 2018
40
A G1-lineage H9N2 virus with oviduct tropism causes chronic pathological changes in the infundibulum and a long-lasting drop in egg production. 61
30157967 2018
41
An integrative investigation of the therapeutic mechanism of Ainsliaea fragrans Champ. in cervicitis using liquid chromatography tandem mass spectrometry based on a rat plasma metabolomics strategy. 61
29729635 2018
42
Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis. 61
29805512 2018
43
Virulence of Escherichia coli Isolates Obtained from Layer Chickens with Colibacillosis Associated with Pericarditis, Perihepatitis, and Salpingitis in Experimentally Infected Chicks and Embryonated Eggs. 61
29944397 2018
44
Histopathologic Features of Postablation Tubal Sterilization Syndrome. 61
29505424 2018
45
Isolation, characterization, and antibiotic sensitivity assessment of Gallibacterium anatis biovar haemolytica, from diseased Egyptian chicken flocks during the years 2013 and 2015. 61
29471426 2018
46
Vaccination with outer membrane vesicles and the fimbrial protein FlfA offers improved protection against lesions following challenge with Gallibacterium anatis. 61
29615242 2018
47
Fitz-Hugh-Curtis syndrome associated with tuberculous salpingitis and peritonitis: a case presentation and review of literature. 61
29558895 2018
48
[Characteristics of the reproductive health of female population in Ukraine]. 61
30737944 2018
49
Identification, differentiation and antibiotic susceptibility of Gallibacterium isolates from diseased poultry. 61
29441195 2018
50
Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice. 61
29624589 2018

Variations for Salpingitis

Expression for Salpingitis

Search GEO for disease gene expression data for Salpingitis.

Pathways for Salpingitis

Pathways related to Salpingitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.89 TNF TLR2 HSPD1
2 10.5 TNF TLR2 CD40LG

GO Terms for Salpingitis

Cellular components related to Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.43 TNF TLR2 HSPD1 CEACAM1 CD40LG CD4
2 membrane raft GO:0045121 9.02 VDAC1 TNF TLR2 HSPD1 CD4

Biological processes related to Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of inflammatory response GO:0050729 9.61 TNF TLR2 HSPD1
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.56 TNF TLR2 CD40LG AMH
3 positive regulation of interleukin-6 production GO:0032755 9.54 TNF TLR2 HSPD1
4 negative regulation of lipid storage GO:0010888 9.4 TNF CRP
5 positive regulation of interleukin-6 secretion GO:2000778 9.33 TNF TLR2 HSPD1
6 regulation of immunoglobulin secretion GO:0051023 9.32 TNF CD40LG
7 positive regulation of interleukin-12 production GO:0032735 9.13 TLR2 HSPD1 CD40LG
8 positive regulation of interleukin-10 production GO:0032733 8.8 TLR2 HSPD1 CD40LG

Molecular functions related to Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.17 VDAC1 TNF TLR2 CRP CEACAM1 CD4

Sources for Salpingitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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