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MCID: SLP003
MIFTS: 34

Salpingitis

Categories: Reproductive diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Salpingitis

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MalaCards integrated aliases for Salpingitis:

Name: Salpingitis 12 55 44 15 72

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases
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External Ids:

Disease Ontology 12 DOID:5733
MeSH 44 D012488
NCIt 50 C26880
SNOMED-CT 68 88157006
ICD10 33 N70.91
UMLS 72 C0036130
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Summaries for Salpingitis

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Disease Ontology : 12 A fallopian tube disease that is characterized by inflammation of the fallopian tube.

MalaCards based summary : Salpingitis is related to fallopian tube disease and chlamydia. An important gene associated with Salpingitis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1). The drugs Ofloxacin and Levofloxacin have been mentioned in the context of this disorder. Affiliated tissues include testes, uterus and ovary, and related phenotype is reproductive system.

Wikipedia : 75 Salpingitis is an infection and inflammation in the Fallopian tubes. It is often used synonymously with... more...

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Related Diseases for Salpingitis

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Diseases in the Salpingitis family:

Acute Salpingitis Chronic Salpingitis

Diseases related to Salpingitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)
# Related Disease Score Top Affiliating Genes
1 fallopian tube disease 32.2 POC1A OVGP1
2 chlamydia 31.6 HSPD1 CRP
3 pelvic inflammatory disease 30.8 HSPD1 CRP CD40LG
4 bacterial infectious disease 30.0 HSPD1 CRP
5 salpingitis isthmica nodosa 12.6
6 chronic gonococcal salpingitis 12.6
7 acute salpingitis 12.4
8 tuberculous salpingitis 12.4
9 chronic salpingitis 12.4
10 acute gonococcal salpingitis 12.4
11 acute eustachian salpingitis 12.2
12 chronic eustachian salpingitis 12.2
13 chronic salpingo-oophoritis 11.9
14 otosalpingitis 11.8
15 acute salpingo-oophoritis 11.7
16 salpingo-oophoritis 11.5
17 pyosalpinx 10.9
18 infertility 10.7
19 peritonitis 10.7
20 ectopic pregnancy 10.7
21 endometritis 10.7
22 endometriosis 10.6
23 appendicitis 10.5
24 cervicitis 10.4
25 fitz-hugh-curtis syndrome 10.3
26 vaginal discharge 10.3
27 haemophilus influenzae 10.3
28 urethritis 10.3
29 conjunctivitis 10.3
30 endometrial cancer 10.2
31 inclusion conjunctivitis 10.2
32 47,xyy 10.2
33 mesenteric lymphadenitis 10.2 HSPD1 CRP
34 endocardium disease 10.2 HSPD1 CRP
35 reactive arthritis 10.2 HSPD1 CRP
36 toxic shock syndrome 10.1
37 ovarian cyst 10.1
38 crohn's disease 10.1
39 tuberculous peritonitis 10.1
40 primary bacterial infectious disease 10.1 HSPD1 CRP
41 acrodermatitis chronica atrophicans 10.1 OVGP1 CD40LG
42 endocarditis 10.1 HSPD1 CRP
43 breast cancer 10.1
44 leiomyoma, uterine 10.1
45 immune deficiency disease 10.1
46 adenomyosis 10.1
47 mycobacterium tuberculosis 1 10.1
48 allergic hypersensitivity disease 10.1
49 parametritis 10.1
50 leiomyoma 10.1

Graphical network of the top 20 diseases related to Salpingitis:



Diseases related to Salpingitis
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Symptoms & Phenotypes for Salpingitis

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MGI Mouse Phenotypes related to Salpingitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 reproductive system MP:0005389 9.02 CD40LG ESPL1 HSPD1 OVGP1 POC1A
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Drugs & Therapeutics for Salpingitis

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Drugs for Salpingitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ofloxacin Approved Phase 4 82419-36-1 4583
2
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
3 Cytochrome P-450 Enzyme Inhibitors Phase 4
4 Renal Agents Phase 4
5 Topoisomerase Inhibitors Phase 4
6 Anti-Bacterial Agents Phase 4
7 Anti-Infective Agents, Urinary Phase 4
8 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
9 Anti-Infective Agents Phase 4
10 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Open-Lable Multicenter Prospective Non-Randomized Trial to Assess the Efficacy and Safety of Morinidazole With Levofloxacin and Sequential of Levofloxacin in Women With Pelvic Inflammatory Disease Recruiting NCT03391440 Phase 4 morinidazole
2 Feasibility of Balloon Dilation of the Eustachian Tubes for Dilatory Dysfunction Under Local Anesthesia Not yet recruiting NCT04055714

Search NIH Clinical Center for Salpingitis

Cochrane evidence based reviews: salpingitis

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Genetic Tests for Salpingitis

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Anatomical Context for Salpingitis

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MalaCards organs/tissues related to Salpingitis:

41
Testes, Uterus, Ovary, Cervix, Colon, Kidney, Lymph Node
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Publications for Salpingitis

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Articles related to Salpingitis:

(show top 50) (show all 1444)
# Title Authors PMID Year
1
PID: clinical and laparoscopic aspects. 9 38
10818418 2000
2
Serological responses of patients with ectopic pregnancy to epitopes of the Chlamydia trachomatis 60 kDa heat shock protein. 9 38
9619577 1998
3
Antibodies to the chlamydial 60 kd heat-shock protein are associated with laparoscopically confirmed perihepatitis. 9 38
9125613 1997
4
Proliferative response to conserved epitopes of the Chlamydia trachomatis and human 60-kilodalton heat-shock proteins by lymphocytes from women with salpingitis. 9 38
7520213 1994
5
Therapeutic effect of human umbilical cord mesenchymal stem cells on tubal factor infertility using a chronic salpingitis murine model. 38
31190174 2019
6
Xanthogranulomatous Salpingitis. 38
31433377 2019
7
Salpingitis Impairs Bovine Tubal Function and Sperm-Oviduct Interaction. 38
31350463 2019
8
Benefits of second-look laparoscopy in the management of pelvic inflammatory disease. 38
30910760 2019
9
B cell activation factor (BAFF) induces inflammation in the human fallopian tube leading to tubal pregnancy. 38
31088412 2019
10
Risk Factors for Tinnitus in 37,692 Patients Followed in General Practices in Germany. 38
30870350 2019
11
[Infertility caused by salpingitis treated based on theory of kidney deficiency and blood stasis]. 38
30989970 2019
12
Specific Chicken Egg Yolk Antibody Improves the Protective Response against Gallibacterium anatis Infection. 38
30559219 2019
13
Risk Factors for Tinnitus in 37,692 Patients Followed in General Practices in Germany. 38
30789569 2019
14
Sarcoidosis of the fallopian tube: A rare case study with confirmed Propionibacterium acnes infection. 38
30178596 2019
15
RETROSPECTIVE STUDY OF MORTALITY IN CAPTIVE STRUTHIONIFORMES IN A FRENCH ZOO (1974-2015). 38
30592921 2018
16
Appendicitis in non-typhoidal salmonella bacteraemia. 38
30364447 2018
17
Diagnostic performance of abdominal point of care ultrasound performed by an emergency physician in acute right iliac fossa pain. 38
30467798 2018
18
Adult bilateral idiopathic occlusion of foramina of Monro: is foraminoplasty really safe and effective? 38
30366894 2018
19
Data on the epidemiology and pathology of anatipestifer disease in Hungary (2010-2014). 38
30264612 2018
20
Autosomal Dominant Polycystic Kidney Disease and Pericardial Effusion. 38
30210723 2018
21
A G1-lineage H9N2 virus with oviduct tropism causes chronic pathological changes in the infundibulum and a long-lasting drop in egg production. 38
30157967 2018
22
An integrative investigation of the therapeutic mechanism of Ainsliaea fragrans Champ. in cervicitis using liquid chromatography tandem mass spectrometry based on a rat plasma metabolomics strategy. 38
29729635 2018
23
Clinical significance of expression of hsa-mir-1247 and hsa-mir-1269a in ectopic pregnancy due to salpingitis. 38
29805512 2018
24
Virulence of Escherichia coli Isolates Obtained from Layer Chickens with Colibacillosis Associated with Pericarditis, Perihepatitis, and Salpingitis in Experimentally Infected Chicks and Embryonated Eggs. 38
29944397 2018
25
Histopathologic Features of Postablation Tubal Sterilization Syndrome. 38
29505424 2018
26
Isolation, characterization, and antibiotic sensitivity assessment of Gallibacterium anatis biovar haemolytica, from diseased Egyptian chicken flocks during the years 2013 and 2015. 38
29471426 2018
27
Vaccination with outer membrane vesicles and the fimbrial protein FlfA offers improved protection against lesions following challenge with Gallibacterium anatis. 38
29615242 2018
28
Fitz-Hugh-Curtis syndrome associated with tuberculous salpingitis and peritonitis: a case presentation and review of literature. 38
29558895 2018
29
Chlamydia trachomatis as the Cause of Infectious Infertility: Acute, Repetitive or Persistent Long-Term Infection? 38
27370345 2018
30
Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice. 38
29624589 2018
31
Identification, differentiation and antibiotic susceptibility of Gallibacterium isolates from diseased poultry. 38
29441195 2018
32
[Characteristics of the reproductive health of female population in Ukraine]. 38
30737944 2018
33
The impact of HSF on endometrium. 38
29489973 2017
34
Tracing GFP-labeled WJMSCs in vivo using a chronic salpingitis model: an animal experiment. 38
29191249 2017
35
Treatment evaluation of Wharton's jelly-derived mesenchymal stem cells using a chronic salpingitis model: an animal experiment. 38
29041961 2017
36
Streptococcus pyogenes: an unusual cause of salpingitis. Case report and review of the literature. 38
28283947 2017
37
An incidental finding of chronic salpingitis complications: Tubo-uterine fistula. 38
28976128 2017
38
Causes of Normal Mortality in Commercial Egg-Laying Chickens. 38
28957010 2017
39
Longitudinal study of transmission of Escherichia coli from broiler breeders to broilers. 38
28757012 2017
40
Assessment of health and welfare of Austrian laying hens at slaughter demonstrates influence of husbandry system and season. 38
28084805 2017
41
In vitro adherence and invasion of primary chicken oviduct epithelial cells by Gallibacterium anatis. 38
28619135 2017
42
Bacterial invasion of the uterus and oviducts in bovine pyometra. 38
28257873 2017
43
MRI in pelvic inflammatory disease: a pictorial review. 38
27933478 2017
44
Presence of Ureaplasma diversum in the genital tracts of female dairy cattle in Mato Grosso State, Brazil. 38
27915439 2017
45
Peritoneal and genital coccidioidomycosis in an otherwise healthy Danish female: a case report. 38
28143444 2017
46
Pelvic inflammatory disease and salpingitis: incidence of primary and repeat episodes in England. 38
27678278 2017
47
Abdominal and pelvic actinomycosis due to longstanding intrauterine device: a slow and devastating infection. 38
28536687 2017
48
Correlation of clinical and biological evidence - a dominant therapeutic element of succeeding in ectopic pregnancy. 38
28523313 2017
49
Neisseria gonorrhoeae Challenge Increases Matrix Metalloproteinase-8 Expression in Fallopian Tube Explants. 38
28932707 2017
50
Congenital Tuberculosis after in-vitro Fertilization in a Woman Previously Undiagnosed with Tuberculosis Salpingitis. 38
27234420 2016
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Variations for Salpingitis

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Expression for Salpingitis

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Search GEO for disease gene expression data for Salpingitis.
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Pathways for Salpingitis

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GO Terms for Salpingitis

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Biological processes related to Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to unfolded protein GO:0006986 9.26 MFN2 HSPD1
2 B cell proliferation GO:0042100 9.16 HSPD1 CD40LG
3 positive regulation of interleukin-12 production GO:0032735 8.96 HSPD1 CD40LG
4 positive regulation of interleukin-10 production GO:0032733 8.62 HSPD1 CD40LG
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Sources for Salpingitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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