MCID: SRC011
MIFTS: 32

Sarcocystosis

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Sarcocystosis

MalaCards integrated aliases for Sarcocystosis:

Name: Sarcocystosis 12 60 45 15 17 74
Sarcosporidiosis 12 60

Classifications:

Orphanet: 60  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:9640
ICD9CM 36 136.5
MeSH 45 D012523
SNOMED-CT 69 88905005
ICD10 34 A07.8
MESH via Orphanet 46 D012523
ICD10 via Orphanet 35 A07.8
UMLS via Orphanet 75 C0036231
Orphanet 60 ORPHA54368
UMLS 74 C0036231

Summaries for Sarcocystosis

Disease Ontology : 12 A coccidiosis that involves infection of the intestine and muscles of humans and animals caused by an intracellular protozoan parasite of genus Sarcocystis. The symptoms include mild fever, diarrhea, chills, vomiting, muscle swelling, erythema, muscle tenderness,cough, arthralgia, transient pruritic rashes, headache, malaise and lymphadenopathy.

MalaCards based summary : Sarcocystosis, also known as sarcosporidiosis, is related to myositis and toxoplasmosis. An important gene associated with Sarcocystosis is SACS (Sacsin Molecular Chaperone), and among its related pathways/superpathways are Alanine, aspartate and glutamate metabolism and Alanine and aspartate metabolism. Affiliated tissues include testes and skeletal muscle, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 77 Sarcocystis is a genus of parasites, the majority of species infecting mammals, and some infecting... more...

Related Diseases for Sarcocystosis

Graphical network of the top 20 diseases related to Sarcocystosis:



Diseases related to Sarcocystosis

Symptoms & Phenotypes for Sarcocystosis

GenomeRNAi Phenotypes related to Sarcocystosis according to GeneCards Suite gene sharing:

27 (show all 22)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.77 IGF1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.77 IGF1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.77 TOM1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.77 TOM1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-132 9.77 TOM1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.77 IGF1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.77 F9
8 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.77 IGF1 TOM1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.77 IGF1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.77 F9 IGF1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.77 F9 IGF1 TOM1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-183 9.77 F9
13 Increased shRNA abundance (Z-score > 2) GR00366-A-208 9.77 F9 IGF1 TOM1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.77 IGF1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.77 TOM1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.77 IGF1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-41 9.77 F9
18 Increased shRNA abundance (Z-score > 2) GR00366-A-44 9.77 F9
19 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.77 TOM1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.77 F9
21 Increased shRNA abundance (Z-score > 2) GR00366-A-88 9.77 F9
22 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.77 IGF1

MGI Mouse Phenotypes related to Sarcocystosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.28 F9 FARSA GAD1 IGF1 PIK3C2A RBFOX1

Drugs & Therapeutics for Sarcocystosis

Search Clinical Trials , NIH Clinical Center for Sarcocystosis

Cochrane evidence based reviews: sarcocystosis

Genetic Tests for Sarcocystosis

Anatomical Context for Sarcocystosis

MalaCards organs/tissues related to Sarcocystosis:

42
Testes, Skeletal Muscle

Publications for Sarcocystosis

Articles related to Sarcocystosis:

(show top 50) (show all 190)
# Title Authors Year
1
Fatal hepatic sarcocystosis in a free-ranging grizzly bear cub associated with Sarcocystis canis-like infection. ( 30698508 )
2019
2
Atypical Presentation of Human Acute Muscular Sarcocystosis: Sarcocystis Nesbitti Confirmed on Molecular Testing. ( 30971680 )
2019
3
Spatial Analysis of a Cat-Borne Disease Reveals That Soil pH and Clay Content Are Risk Factors for Sarcocystosis in Sheep. ( 31069240 )
2019
4
Sarcosporidiosis: An Emerging Disease in Yaks (Bos grunniens) on the Qinghai Tibetan Plateau (QTP), China. ( 30778839 )
2019
5
Sarcocystosis in South American camelids: The state of play revisited. ( 29510746 )
2018
6
An update on sarcocystosis in one-humped camels (Camelus dromedarius). ( 29866208 )
2018
7
Immunoprotective responses against murine sarcocystosis by β - Irradiated sporocysts. ( 29964018 )
2018
8
Seroprevalence of sarcocystosis in the local communities of Pangkor and Tioman Islands using recombinant surface antigens 3 (rSAG3) of Sarcocystis falcatula. ( 30286271 )
2018
9
Acute fatal sarcocystosis hepatitis in an Indo-Pacific bottlenose dolphin (Tursiops aduncus) in Hong Kong. ( 28215870 )
2017
10
First report of human intestinal sarcocystosis in Cambodia. ( 28476340 )
2017
11
Muscular sarcocystosis: an index case in a native Malaysian. ( 28747414 )
2017
12
Diagnosis of bovine sarcocystosis by immunoflourescent antibody technique. ( 28848280 )
2017
13
Atypical fatal sarcocystosis associated with Sarcocystis neurona in a White-nosed coati (Nasua narica molaris). ( 29080770 )
2017
14
Prevalence of Muscular Sarcosporidiosis in Slaughtered Domestic Pigs in Perak, Peninsular Malaysia. ( 28228924 )
2017
15
Sarcocystosis in wild red deer (Cervus elaphus) in Patagonia, Argentina. ( 26779923 )
2016
16
Pathology, immunohistochemistry, and ultrastructural findings associated with neurological sarcocystosis in cattle. ( 27198793 )
2016
17
Human intestinal sarcocystosis in Iran: there but not seen. ( 27637226 )
2016
18
Cross-sectional investigation on sheep sarcosporidiosis in Sardinia, Italy. ( 31014493 )
2016
19
Meningoencephalitis associated with disseminated sarcocystosis in a free-ranging moose (Alces alces) calf. ( 26246636 )
2015
20
Prolonged clinical course of muscular sarcocystosis and effectiveness of cotrimoxazole among travelers to Tioman Island, Malaysia, 2011-2014. ( 25301217 )
2015
21
In the United States, negligible rates of zoonotic sarcocystosis occur in feral swine that, by contrast, frequently harbour infections with Sarcocystis miescheriana, a related parasite contracted from canids. ( 25363485 )
2015
22
Avoid haste in defining human muscular sarcocystosis. ( 25537869 )
2015
23
Detection of sarcocystosis in goats in Malaysia by light microscopy, histology, and PCR. ( 25740651 )
2015
24
Human Invasive Muscular Sarcocystosis Induces Th2 Cytokine Polarization and Biphasic Cytokine Changes, Based on an Investigation among Travelers Returning from Tioman Island, Malaysia. ( 25903356 )
2015
25
Human Extraintestinal Sarcocystosis: What We Know, and What We don't Know. ( 26115699 )
2015
26
Foray of Cytologically Diagnosed Intramuscular Sarcocystosis- A Rarity. ( 26155487 )
2015
27
A review of sarcocystosis in camels and redescription of Sarcocystis cameli and Sarcocystis ippeni sarcocysts from the one-humped camel (Camelus dromedarius). ( 26416197 )
2015
28
Sarcocystosis in Cervus elaphus: Comparison of diagnostic methods. ( 26767167 )
2015
29
Sarcocystis nesbitti causes acute, relapsing febrile myositis with a high attack rate: description of a large outbreak of muscular sarcocystosis in Pangkor Island, Malaysia, 2012. ( 24854350 )
2014
30
Muscular sarcocystosis in two arctic foxes (Vulpes lagopus) due to Sarcocystis arctica n. sp.: sarcocyst morphology, molecular characteristics and phylogeny. ( 24297693 )
2014
31
Current status of epidemiology and diagnosis of human sarcocystosis. ( 24759707 )
2014
32
Suspected new wave of muscular sarcocystosis in travellers returning from Tioman Island, Malaysia, May 2014. ( 24906376 )
2014
33
Acute muscular sarcocystosis: an international investigation among ill travelers returning from Tioman Island, Malaysia, 2011-2012. ( 25091309 )
2014
34
Sarcocystosis in a stillborn lamb. ( 25220847 )
2014
35
Neglected tropical diseases among two indigenous subtribes in peninsular Malaysia: highlighting differences and co-infection of helminthiasis and sarcocystosis. ( 25248116 )
2014
36
What is your neurologic diagnosis? Sarcocystosis in a horse. ( 24004221 )
2013
37
Human and animal invasive muscular sarcocystosis in Malaysia--recent cases, review and hypotheses. ( 24189667 )
2013
38
Sarcocystis and sarcocystosis in India: status and emerging perspectives. ( 24431532 )
2013
39
High prevalence of muscular sarcocystosis in cattle and water buffaloes from Selangor, Malaysia. ( 24522140 )
2013
40
Notes from the field: acute muscular sarcocystosis among returning travelers - Tioman Island, Malaysia, 2011. ( 22258418 )
2012
41
Laryngeal sarcocystosis accompanying laryngeal squamous cell carcinoma: case report and literature review. ( 22299431 )
2011
42
First report of naturally acquired clinical sarcocystosis in a pig breeding stock. ( 21145659 )
2011
43
Fatal hepatic sarcocystosis in a captive black bear (Ursus americanus) associated with Sarcocystis canis-like infection. ( 21398469 )
2011
44
Mineral status of myocardial sarcocystosis. ( 22347283 )
2011
45
Systemic sarcocystosis in a striped skunk (Mephitis mephitis). ( 20375428 )
2010
46
Sarcocystosis among wild captive and zoo animals in Malaysia. ( 20877499 )
2010
47
Muscular sarcocystosis in wild carnivores in Honshu, Japan. ( 19841942 )
2009
48
Clinical presentation and pathology of sarcocystosis in psittaciform birds: 11 cases. ( 18459322 )
2008
49
Systemic sarcocystosis in a patient with acquired immune deficiency syndrome. ( 18602666 )
2008
50
An outbreak of sarcocystosis in psittacines and a pigeon in a zoological collection in Brazil. ( 19166069 )
2008

Variations for Sarcocystosis

Expression for Sarcocystosis

Search GEO for disease gene expression data for Sarcocystosis.

Pathways for Sarcocystosis

Pathways related to Sarcocystosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.51 GAD1 GPT
2
Show member pathways
9.74 GAD1 GPT

GO Terms for Sarcocystosis

Biological processes related to Sarcocystosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuromuscular process controlling balance GO:0050885 9.26 RBFOX1 RBFOX2
2 phosphatidylinositol-mediated signaling GO:0048015 9.16 IGF1 PIK3C2A
3 regulation of RNA splicing GO:0043484 8.96 RBFOX1 RBFOX2
4 phosphatidylinositol 3-kinase signaling GO:0014065 8.62 IGF1 PIK3C2A

Molecular functions related to Sarcocystosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pyridoxal phosphate binding GO:0030170 8.62 GAD1 GPT

Sources for Sarcocystosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....