MCID: SRC011
MIFTS: 31

Sarcocystosis

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Sarcocystosis

MalaCards integrated aliases for Sarcocystosis:

Name: Sarcocystosis 12 59 44 15 73
Sarcosporidiosis 12 59

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:9640
ICD10 33 A07.8
ICD9CM 35 136.5
MeSH 44 D012523
SNOMED-CT 68 88905005
Orphanet 59 ORPHA54368
MESH via Orphanet 45 D012523
UMLS via Orphanet 74 C0036231
ICD10 via Orphanet 34 A07.8
UMLS 73 C0036231

Summaries for Sarcocystosis

Disease Ontology : 12 A coccidiosis that involves infection of the intestine and muscles of humans and animals caused by an intracellular protozoan parasite of genus Sarcocystis. The symptoms include mild fever, diarrhea, chills, vomiting, muscle swelling, erythema, muscle tenderness,cough, arthralgia, transient pruritic rashes, headache, malaise and lymphadenopathy.

MalaCards based summary : Sarcocystosis, also known as sarcosporidiosis, is related to myositis and toxoplasmosis. An important gene associated with Sarcocystosis is SACS (Sacsin Molecular Chaperone), and among its related pathways/superpathways is MECP2 and Associated Rett Syndrome. Affiliated tissues include skeletal muscle and testes, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 76 Sarcocystis is a genus of parasites, the majority of species infecting mammals, and some infecting... more...

Related Diseases for Sarcocystosis

Diseases related to Sarcocystosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 24)
# Related Disease Score Top Affiliating Genes
1 myositis 10.3
2 toxoplasmosis 10.2
3 diabetes mellitus, ketosis-prone 10.0 GAD1 PIK3C2A
4 atrioventricular block 10.0
5 second-degree atrioventricular block 10.0
6 cysticercosis 10.0
7 theileriasis 10.0
8 trichinosis 10.0
9 polyarteritis nodosa, childhood-onset 9.9
10 hepatitis 9.9
11 meningoencephalitis 9.9
12 giardiasis 9.9
13 rabies 9.9
14 cryptosporidiosis 9.9
15 squamous cell carcinoma 9.9
16 coccidiosis 9.9
17 laryngeal squamous cell carcinoma 9.9
18 lymphosarcoma 9.9
19 encephalitis 9.9
20 polyarteritis nodosa 9.9
21 polymyositis 9.9
22 disseminated intravascular coagulation 9.9 F9 PIK3C2A
23 parasitic ectoparasitic infectious disease 9.9 FARSA PYURF
24 interstitial myocarditis 9.9 PIK3C2A PYURF

Graphical network of the top 20 diseases related to Sarcocystosis:



Diseases related to Sarcocystosis

Symptoms & Phenotypes for Sarcocystosis

GenomeRNAi Phenotypes related to Sarcocystosis according to GeneCards Suite gene sharing:

26 (show all 22)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 10.07 IGF1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-114 10.07 IGF1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-123 10.07 TOM1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-13 10.07 TOM1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-132 10.07 TOM1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-138 10.07 IGF1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-157 10.07 F9
8 Increased shRNA abundance (Z-score > 2) GR00366-A-161 10.07 IGF1 TOM1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-163 10.07 IGF1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-164 10.07 F9 IGF1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-176 10.07 F9 IGF1 TOM1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-183 10.07 F9
13 Increased shRNA abundance (Z-score > 2) GR00366-A-208 10.07 F9 IGF1 TOM1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-21 10.07 IGF1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-214 10.07 TOM1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-29 10.07 IGF1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-41 10.07 F9
18 Increased shRNA abundance (Z-score > 2) GR00366-A-44 10.07 F9
19 Increased shRNA abundance (Z-score > 2) GR00366-A-63 10.07 TOM1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-81 10.07 F9
21 Increased shRNA abundance (Z-score > 2) GR00366-A-88 10.07 F9
22 Increased shRNA abundance (Z-score > 2) GR00366-A-99 10.07 IGF1

MGI Mouse Phenotypes related to Sarcocystosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.23 F9 FARSA GAD1 IGF1 PIK3C2A RBFOX1

Drugs & Therapeutics for Sarcocystosis

Search Clinical Trials , NIH Clinical Center for Sarcocystosis

Cochrane evidence based reviews: sarcocystosis

Genetic Tests for Sarcocystosis

Anatomical Context for Sarcocystosis

MalaCards organs/tissues related to Sarcocystosis:

41
Skeletal Muscle, Testes

Publications for Sarcocystosis

Articles related to Sarcocystosis:

(show top 50) (show all 183)
# Title Authors Year
1
Immunoprotective responses against murine sarcocystosis by I^ - Irradiated sporocysts. ( 29964018 )
2018
2
Sarcocystosis in South American camelids: The state of play revisited. ( 29510746 )
2018
3
An update on sarcocystosis in one-humped camels (Camelus dromedarius). ( 29866208 )
2018
4
Seroprevalence of sarcocystosis in the local communities of Pangkor and Tioman Islands using recombinant surface antigens 3 (rSAG3) of Sarcocystis falcatula. ( 30286271 )
2018
5
Diagnosis of bovine sarcocystosis by immunoflourescent antibody technique. ( 28848280 )
2017
6
First report of human intestinal sarcocystosis in Cambodia. ( 28476340 )
2017
7
Acute fatal sarcocystosis hepatitis in an Indo-Pacific bottlenose dolphin (Tursiops aduncus) in Hong Kong. ( 28215870 )
2017
8
Muscular sarcocystosis: an index case in a native Malaysian. ( 28747414 )
2017
9
Atypical fatal sarcocystosis associated with Sarcocystis neurona in a White-nosed coati (Nasua narica molaris). ( 29080770 )
2017
10
Prevalence of Muscular Sarcosporidiosis in Slaughtered Domestic Pigs in Perak, Peninsular Malaysia. ( 28228924 )
2017
11
Pathology, immunohistochemistry, and ultrastructural findings associated with neurological sarcocystosis in cattle. ( 27198793 )
2016
12
Sarcocystosis in wild red deer (Cervus elaphus) in Patagonia, Argentina. ( 26779923 )
2016
13
Human intestinal sarcocystosis in Iran: there but not seen. ( 27637226 )
2016
14
Foray of Cytologically Diagnosed Intramuscular Sarcocystosis- A Rarity. ( 26155487 )
2015
15
A review of sarcocystosis in camels and redescription of Sarcocystis cameli and Sarcocystis ippeni sarcocysts from the one-humped camel (Camelus dromedarius). ( 26416197 )
2015
16
Meningoencephalitis associated with disseminated sarcocystosis in a free-ranging moose (Alces alces) calf. ( 26246636 )
2015
17
Detection of sarcocystosis in goats in Malaysia by light microscopy, histology, and PCR. ( 25740651 )
2015
18
Avoid haste in defining human muscular sarcocystosis. ( 25537869 )
2015
19
Human Extraintestinal Sarcocystosis: What We Know, and What We don't Know. ( 26115699 )
2015
20
Human invasive muscular sarcocystosis induces Th2 cytokine polarization and biphasic cytokine changes - an investigation among returning travelers from Tioman Island, Malaysia. ( 25903356 )
2015
21
Sarcocystosis in Cervus elaphus: Comparison of diagnostic methods. ( 26767167 )
2015
22
Sarcocystis nesbitti causes acute, relapsing febrile myositis with a high attack rate: description of a large outbreak of muscular sarcocystosis in Pangkor Island, Malaysia, 2012. ( 24854350 )
2014
23
Current status of epidemiology and diagnosis of human sarcocystosis. ( 24759707 )
2014
24
In the United States, negligible rates of zoonotic sarcocystosis occur in feral swine that, by contrast, frequently harbour infections with Sarcocystis miescheriana, a related parasite contracted from canids. ( 25363485 )
2014
25
Prolonged Clinical Course of Muscular Sarcocystosis and Effectiveness of Cotrimoxazole Among Travelers to Tioman Island, Malaysia, 2011-2014. ( 25301217 )
2014
26
Acute muscular sarcocystosis: an international investigation among ill travelers returning from tioman island, malaysia, 2011-2012. ( 25091309 )
2014
27
Neglected tropical diseases among two indigenous subtribes in peninsular Malaysia: highlighting differences and co-infection of helminthiasis and sarcocystosis. ( 25248116 )
2014
28
Sarcocystosis in a stillborn lamb. ( 25220847 )
2014
29
Suspected new wave of muscular sarcocystosis in travellers returning from Tioman Island, Malaysia, May 2014. ( 24906376 )
2014
30
Muscular sarcocystosis in two arctic foxes (Vulpes lagopus) due to Sarcocystis arctica n. sp.: sarcocyst morphology, molecular characteristics and phylogeny. ( 24297693 )
2013
31
Human and animal invasive muscular sarcocystosis in Malaysia--recent cases, review and hypotheses. ( 24189667 )
2013
32
Sarcocystis and sarcocystosis in India: status and emerging perspectives. ( 24431532 )
2013
33
High prevalence of muscular sarcocystosis in cattle and water buffaloes from Selangor, Malaysia. ( 24522140 )
2013
34
Notes from the field: acute muscular sarcocystosis among returning travelers - Tioman Island, Malaysia, 2011. ( 22258418 )
2012
35
Mineral status of myocardial sarcocystosis. ( 22347283 )
2011
36
Fatal hepatic sarcocystosis in a captive black bear (Ursus americanus) associated with Sarcocystis canis-like infection. ( 21398469 )
2011
37
Laryngeal sarcocystosis accompanying laryngeal squamous cell carcinoma: case report and literature review. ( 22299431 )
2011
38
First report of naturally acquired clinical sarcocystosis in a pig breeding stock. ( 21145659 )
2011
39
Sarcocystosis among wild captive and zoo animals in Malaysia. ( 20877499 )
2010
40
Systemic sarcocystosis in a striped skunk (Mephitis mephitis). ( 20375428 )
2010
41
Muscular sarcocystosis in wild carnivores in Honshu, Japan. ( 19841942 )
2009
42
Systemic sarcocystosis in a patient with acquired immune deficiency syndrome. ( 18602666 )
2008
43
Clinical presentation and pathology of sarcocystosis in psittaciform birds: 11 cases. ( 18459322 )
2008
44
An outbreak of sarcocystosis in psittacines and a pigeon in a zoological collection in Brazil. ( 19166069 )
2008
45
Chronic polymyositis associated with disseminated Sarcocystosis in a captive-born rhesus macaque. ( 17846244 )
2007
46
The potential usefulness of the modified Kato thick smear technique in the detection of intestinal sarcocystosis during field surveys. ( 17539271 )
2007
47
The Sarcocystis-cyst containing beef and pork as the sources of natural intestinal sarcocystosis in Thai people. ( 18041433 )
2007
48
Fatal hepatic sarcocystosis in a puppy with eosinophilia and eosinophilic peritoneal effusion. ( 16967426 )
2006
49
Neosporosis, toxoplasmosis, and sarcocystosis in ruminants. ( 17071358 )
2006
50
Sarcocystosis of Sarcocystis felis in cats. ( 17153714 )
2006

Variations for Sarcocystosis

Expression for Sarcocystosis

Search GEO for disease gene expression data for Sarcocystosis.

Pathways for Sarcocystosis

Pathways related to Sarcocystosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.42 GAD1 RBFOX1

GO Terms for Sarcocystosis

Biological processes related to Sarcocystosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of alternative mRNA splicing, via spliceosome GO:0000381 9.32 RBFOX1 RBFOX2
2 neuromuscular process controlling balance GO:0050885 9.26 RBFOX1 RBFOX2
3 phosphatidylinositol-mediated signaling GO:0048015 9.16 IGF1 PIK3C2A
4 regulation of RNA splicing GO:0043484 8.96 RBFOX1 RBFOX2
5 phosphatidylinositol 3-kinase signaling GO:0014065 8.62 IGF1 PIK3C2A

Sources for Sarcocystosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....