Sarcoid Meningitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Sarcoid Meningitis

MalaCards integrated aliases for Sarcoid Meningitis:

Name: Sarcoid Meningitis ¹² ¹⁵ ⁷¹

Meningitis in Sarcoidosis ¹²

Classifications:

MalaCards categories:
Anatomical: Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:12055

ICD9CM ³⁴ 321.4

ICD10 ³² D86.81

UMLS ⁷¹ C0154648

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Summaries for Sarcoid Meningitis

MalaCards based summary : Sarcoid Meningitis, also known as meningitis in sarcoidosis, is related to neurosarcoidosis and meningitis. An important gene associated with Sarcoid Meningitis is ADIRF (Adipogenesis Regulatory Factor), and among its related pathways/superpathways is VEGF Pathway (Tocris). Affiliated tissues include kidney and skin, and related phenotypes are growth/size/body region and hematopoietic system

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Related Diseases for Sarcoid Meningitis

Diseases related to Sarcoid Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)

#	Related Disease	Score	Top Affiliating Genes
1	neurosarcoidosis	30.1	TNFRSF1B ACE
2	meningitis	10.2
3	acute anterolateral myocardial infarction	10.1	PIK3C2A ACE
4	orbital plasma cell granuloma	10.1	TNFRSF1B PIK3C2A
5	granulomatous myositis	10.1	PIK3C2A ACE
6	left bundle branch hemiblock	10.1	PIK3C2A ACE
7	coronary artery vasospasm	10.1	PIK3C2A ACE
8	cardiac tamponade	10.1	PIK3C2A ACE
9	anuria	10.1	PIK3C2A ACE
10	pseudohyperkalemia, familial, 2, due to red cell leak	10.1	PIK3C2A ACE
11	childhood type dermatomyositis	10.1	TNFRSF1B PIK3C2A
12	acute kidney tubular necrosis	10.1	PIK3C2A ACE
13	aspiration pneumonia	10.1	PIK3C2A ACE
14	chronic orbital inflammation	10.1	TNFRSF1B ACE
15	anterior scleritis	10.1	TNFRSF1B ACE
16	skin sarcoidosis	10.1	TNFRSF1B ACE
17	optic papillitis	10.1	TNFRSF1B ACE
18	granulomatous hepatitis	10.0	TNFRSF1B ACE
19	intermediate coronary syndrome	10.0	PIK3C2A ACE
20	granulomatous dermatitis	10.0	TNFRSF1B ACE
21	angina pectoris	10.0	PIK3C2A ACE
22	scleral disease	10.0	TNFRSF1B ACE
23	iritis	10.0	TNFRSF1B ACE
24	chorioretinitis	10.0	TNFRSF1B ACE
25	endocardium disease	10.0	PIK3C2A ACE
26	iridocyclitis	10.0	TNFRSF1B ACE
27	macular dystrophy, dominant cystoid	10.0	TNFRSF1B ACE
28	pericardial effusion	10.0	PIK3C2A ACE
29	retinal vasculitis	10.0	TNFRSF1B ACE
30	extrinsic cardiomyopathy	10.0	PIK3C2A ACE
31	panuveitis	10.0	TNFRSF1B ACE
32	chronic meningitis	10.0
33	atrioventricular block	10.0	PIK3C2A ACE
34	coronary stenosis	10.0	PIK3C2A ACE
35	angiokeratoma of fordyce	10.0	FLT1 ACE
36	hypersensitivity reaction type iv disease	10.0	TNFRSF1B ACE
37	peripartum cardiomyopathy	9.9	FLT1 ACE
38	retinal artery occlusion	9.9	FLT1 ACE
39	uveal disease	9.9	TNFRSF1B ACE
40	sarcoidosis 1	9.8
41	hydrocephalus	9.8
42	cauda equina syndrome	9.8
43	dementia	9.8
44	communicating hydrocephalus	9.8
45	polyradiculopathy	9.8
46	subacute delirium	9.8
47	headache	9.8
48	eclampsia	9.8	FLT1 ACE
49	ectopic pregnancy	9.8	PIK3C2A FLT1
50	post-transplant lymphoproliferative disease	9.8	TNFRSF1B B2M

Graphical network of the top 20 diseases related to Sarcoid Meningitis:

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Symptoms & Phenotypes for Sarcoid Meningitis

MGI Mouse Phenotypes related to Sarcoid Meningitis:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	growth/size/body region	MP:0005378	9.63	ACE B2M FLT1 ITGAE PIK3C2A TNFRSF1B
2	hematopoietic system	MP:0005397	9.43	ACE B2M FLT1 ITGAE PIK3C2A TNFRSF1B
3	immune system	MP:0005387	9.1	ACE B2M FLT1 ITGAE PIK3C2A TNFRSF1B

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Drugs & Therapeutics for Sarcoid Meningitis

Search Clinical Trials , NIH Clinical Center for Sarcoid Meningitis

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Genetic Tests for Sarcoid Meningitis

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Anatomical Context for Sarcoid Meningitis

MalaCards organs/tissues related to Sarcoid Meningitis:

⁴⁰

Kidney, Skin

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Publications for Sarcoid Meningitis

Articles related to Sarcoid Meningitis:

#	Title	Authors	PMID	Year
1	Sarcoid meningitis with fulminant delirium and markedly abnormal cerebrospinal fluid. ⁶¹	Noble JM...Adams DJ	17210821	2007
2	Role of radiotherapy in the treatment of neurosarcoidosis. ⁶¹	Menninger MD...Marcus RB	12902908	2003
3	Shunt-responsive dementia in sarcoid meningitis: role of magnetic resonance imaging and cisternography. ⁶¹	Scott TF...Brillman J	10918749	2000
4	Cerebral herniation after lumbar puncture in sarcoid meningitis. ⁶¹	Scott TF	10717399	2000
5	Biopsy-proven isolated sarcoid meningitis. Case report. ⁶¹	Mayer SA...Marder K	8487086	1993
6	Progression of hydrocephalus during corticosteroid therapy for neurosarcoidosis. ⁶¹	Foley KT...Junck L	2602241	1989
7	Sarcoid meningitis, high adenosine deaminase levels in CSF and results of cranial irradiation. ⁶¹	Garcia-Monco C...Berciano J	3221231	1988
8	Treatment of sarcoid meningitis with radiotherapy. ⁶¹	Grizzanti JN...Williams MH	6812421	1982

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Genes for Sarcoid Meningitis

Genes related to Sarcoid Meningitis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ADIRF	Adipogenesis Regulatory Factor	Protein Coding	4.32	DISEASES inferred ¹⁵
2	ITGAE	Integrin Subunit Alpha E	Protein Coding	4.32	DISEASES inferred ¹⁵
3	PIK3C2A	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha	Protein Coding	4.19	DISEASES inferred ¹⁵
4	ACE	Angiotensin I Converting Enzyme	Protein Coding	3.8	DISEASES inferred ¹⁵
5	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	3.7	DISEASES inferred ¹⁵
6	B2M	Beta-2-Microglobulin	Protein Coding	3.68	DISEASES inferred ¹⁵
7	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	3.59	DISEASES inferred ¹⁵

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Variations for Sarcoid Meningitis

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Expression for Sarcoid Meningitis

Search GEO for disease gene expression data for Sarcoid Meningitis.

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Pathways for Sarcoid Meningitis

Pathways related to Sarcoid Meningitis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	VEGF Pathway (Tocris) ⁶⁰ Show member pathways VEGF Pathway ⁷⁰	10.54	PIK3C2A FLT1

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GO Terms for Sarcoid Meningitis

Biological processes related to Sarcoid Meningitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of protein binding	GO:0032092	8.96	B2M ACE
2	antigen processing and presentation of peptide antigen via MHC class I	GO:0002474	8.62	B2M ACE

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Sources for Sarcoid Meningitis

¹ BioSystems

² BitterDB

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⁴ Cell Signaling Technology

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²³ GeneHancer via GeneCards

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²⁵ Genetics Home Reference

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²⁷ GEO DataSets

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³³ ICD10 via Orphanet

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³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

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⁴⁰ MalaCards

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⁴⁷ NCBI Bookshelf

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⁵¹ NIH Clinical Center

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⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

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⁶¹ PubMed

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⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia