MCID: SRC007
MIFTS: 23

Sarcomatoid Transitional Cell Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Sarcomatoid Transitional Cell Carcinoma

MalaCards integrated aliases for Sarcomatoid Transitional Cell Carcinoma:

Name: Sarcomatoid Transitional Cell Carcinoma 12 15
Transitional Cell Carcinoma, Spindle Cell 70
Transitional Cell Carcinoma, Sarcomatoid 12
Transitional Spindle Cell Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4014
NCIt 50 C4120
SNOMED-CT 67 112676006
UMLS 70 C0334271

Summaries for Sarcomatoid Transitional Cell Carcinoma

Disease Ontology : 12 A transitional cell carcinoma that has sarcoma-like components arising from the malignant transitional epithelium.

MalaCards based summary : Sarcomatoid Transitional Cell Carcinoma, also known as transitional cell carcinoma, spindle cell, is related to bladder sarcomatoid transitional cell carcinoma and kidney pelvis sarcomatoid transitional cell carcinoma. An important gene associated with Sarcomatoid Transitional Cell Carcinoma is CD68 (CD68 Molecule), and among its related pathways/superpathways is Glioma. Related phenotypes are integument and neoplasm

Related Diseases for Sarcomatoid Transitional Cell Carcinoma

Diseases related to Sarcomatoid Transitional Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 196)
# Related Disease Score Top Affiliating Genes
1 bladder sarcomatoid transitional cell carcinoma 11.7
2 kidney pelvis sarcomatoid transitional cell carcinoma 11.5
3 transitional cell carcinoma 10.4
4 heart lymphoma 10.2 CD68 ALK
5 malignant giant cell tumor of the tendon sheath 10.2 CD68 ALK
6 pseudosarcomatous fibromatosis 10.2 CD68 ALK
7 fibrous histiocytoma 10.2 CD68 ALK
8 maxillary sinus benign neoplasm 10.2 CDH1 ALK
9 pericardium disease 10.2 CD68 ALK
10 reticulosarcoma 10.2 CD68 ALK
11 myoblastoma 10.2 SYP CD68
12 lymphoepithelioma-like carcinoma 10.2 CDH1 ALK
13 pericardial effusion 10.1 CD68 ALK
14 pulmonary large cell neuroendocrine carcinoma 10.1 SYP ALK
15 large cell neuroendocrine carcinoma 10.1 SYP ALK
16 myxoid chondrosarcoma 10.1 SYP CD68
17 large cell medulloblastoma 10.1 SYP ALK
18 autonomic nervous system benign neoplasm 10.1 SYP ALK
19 peripheral nervous system benign neoplasm 10.1 SYP ALK
20 conjunctival pigmentation 10.1 MLANA CD68
21 sarcomatoid squamous cell skin carcinoma 10.1 MLANA CD68
22 breast neuroendocrine neoplasm 10.1 SYP CDH1
23 skin sarcoma 10.1 MLANA CD68
24 balloon cell malignant melanoma 10.1 MLANA CD68
25 malignant granular cell myoblastoma 10.1 MLANA CD68
26 pulmonary sclerosing hemangioma 10.1 SYP CDH1
27 fibrolamellar carcinoma 10.1 SYP CD68
28 bladder sarcoma 10.1 MLANA CD68
29 epithelioid sarcoma 10.1 SYP CD68
30 carcinosarcoma 10.1
31 rare tumor 10.1
32 ganglioneuroblastoma 10.1 SYP ALK
33 cutaneous fibrous histiocytoma 10.1 MLANA CD68
34 spitzoid melanoma 10.1 MLANA ALK
35 tubular adenocarcinoma 10.1 SYP CDH1
36 malignant leptomeningeal tumor 10.0 TYR MLANA
37 meningeal melanoma 10.0 TYR MLANA
38 ciliary body cancer 10.0 TYR MLANA
39 melanoacanthoma 10.0 TYR MLANA
40 halo nevi 10.0 TYR MLANA
41 melanomatosis 10.0 TYR MLANA
42 diffuse meningeal melanocytosis 10.0 TYR MLANA
43 glomangiosarcoma 10.0 SYP MLANA
44 sensory organ benign neoplasm 10.0 SYP MLANA
45 benign perivascular tumor 10.0 SYP MLANA
46 perivascular tumor 10.0 SYP MLANA
47 epithelioid cell melanoma 10.0 TYR MLANA
48 olfactory nerve neoplasm 10.0 SYP MLANA
49 cranial nerve malignant neoplasm 10.0 SYP MLANA
50 cranial nerve neoplasm 10.0 SYP MLANA

Graphical network of the top 20 diseases related to Sarcomatoid Transitional Cell Carcinoma:



Diseases related to Sarcomatoid Transitional Cell Carcinoma

Symptoms & Phenotypes for Sarcomatoid Transitional Cell Carcinoma

MGI Mouse Phenotypes related to Sarcomatoid Transitional Cell Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.72 ALK CDH1 MLANA TP53 TYR
2 neoplasm MP:0002006 9.56 ALK CDH1 TP53 TYR
3 no phenotypic analysis MP:0003012 9.55 CD68 CDH1 MLANA TP53 TYR
4 normal MP:0002873 9.35 ALK CDH1 SYP TP53 TYR
5 pigmentation MP:0001186 8.92 ALK MLANA TP53 TYR

Drugs & Therapeutics for Sarcomatoid Transitional Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Sarcomatoid Transitional Cell Carcinoma

Genetic Tests for Sarcomatoid Transitional Cell Carcinoma

Anatomical Context for Sarcomatoid Transitional Cell Carcinoma

Publications for Sarcomatoid Transitional Cell Carcinoma

Articles related to Sarcomatoid Transitional Cell Carcinoma:

# Title Authors PMID Year
1
Pyonephrosis as a sign of sarcomatoid carcinoma of the renal pelvis. 61
24945010 2014
2
Sarcomatoid carcinoma of the renal pelvis with giant cell tumor-like features: case report with immunohistochemical findings. 61
15733116 2005
3
Fine needle aspiration biopsy of primary renal synovial sarcoma. A case report. 61
12920764 2003
4
Sarcomatoid transitional cell carcinoma of bladder managed with transurethral resection alone. 61
11792937 2002
5
Sarcomatoid transitional cell carcinoma originating from a duplicated renal pelvis. 61
11851772 2001
6
Myxoid and sclerosing sarcomatoid transitional cell carcinoma of the urinary bladder: a clinicopathologic and immunohistochemical study of 25 cases. 61
9310954 1997
7
Sarcomatoid transitional cell carcinoma of the renal pelvis. A report of five cases with clinical, pathological, immunohistochemical and DNA ploidy analysis. 61
9182292 1996

Variations for Sarcomatoid Transitional Cell Carcinoma

Expression for Sarcomatoid Transitional Cell Carcinoma

Search GEO for disease gene expression data for Sarcomatoid Transitional Cell Carcinoma.

Pathways for Sarcomatoid Transitional Cell Carcinoma

Pathways related to Sarcomatoid Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.4 TP53 CDH1 ALK

GO Terms for Sarcomatoid Transitional Cell Carcinoma

Cellular components related to Sarcomatoid Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 9.17 TYR TP53 SYP MLANA CDH1 CD68

Biological processes related to Sarcomatoid Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to UV GO:0009411 8.62 TYR TP53

Molecular functions related to Sarcomatoid Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 copper ion binding GO:0005507 9.16 TYR TP53
2 identical protein binding GO:0042802 9.02 TYR TP53 SYP CDH1 ALK
3 protein self-association GO:0043621 8.96 TP53 SYP

Sources for Sarcomatoid Transitional Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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