Aliases & Classifications for Sarcomatosis

MalaCards integrated aliases for Sarcomatosis:

Name: Sarcomatosis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7615
NCIt 50 C4243
SNOMED-CT 68 189765009 9395006
UMLS 73 C0334451

Summaries for Sarcomatosis

Disease Ontology : 12 A sarcoma that results in the formation of numerous sarcomas or located in various parts of the body.

MalaCards based summary : Sarcomatosis is related to clear cell sarcoma and sarcomatosis of the meninges. An important gene associated with Sarcomatosis is CREB3L1 (CAMP Responsive Element Binding Protein 3 Like 1), and among its related pathways/superpathways are TGF-beta Signaling Pathways and Transcriptional misregulation in cancer. The drugs Cisplatin and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include various parts of the body, spinal cord and brain.

Related Diseases for Sarcomatosis

Graphical network of the top 20 diseases related to Sarcomatosis:



Diseases related to Sarcomatosis

Symptoms & Phenotypes for Sarcomatosis

Drugs & Therapeutics for Sarcomatosis

Drugs for Sarcomatosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved 15663-27-1 84093 441203 2767
2
Doxorubicin Approved, Investigational 23214-92-8 31703
3
Oxaliplatin Approved, Investigational 61825-94-3 5310940 9887054 43805 6857599
4
Melphalan Approved 148-82-3 4053 460612
5
Doxil Approved June 1999 31703
6 Mitomycins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 HIPEC For Peritoneal Surface Malignancies Including Carcinomatosis or Sarcomatosis ‐ Data Registry Recruiting NCT02082886
2 Prospective Follow-up of Outcomes in Patients Receiving Photodynamic Therapy for Neoplastic Diseases Recruiting NCT02159742

Search NIH Clinical Center for Sarcomatosis

Genetic Tests for Sarcomatosis

Anatomical Context for Sarcomatosis

The Foundational Model of Anatomy Ontology organs/tissues related to Sarcomatosis:

19
Various Parts Of The Body

MalaCards organs/tissues related to Sarcomatosis:

41
Spinal Cord, Brain, Lung, Spleen, Liver

Publications for Sarcomatosis

Articles related to Sarcomatosis:

(show top 50) (show all 80)
# Title Authors Year
1
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in seven patients with peritoneal sarcomatosis from uterine sarcoma. ( 29881584 )
2018
2
Peritoneal sarcomatosis 5 years after laparoscopic morcellation of uterine leiomyoma. ( 29338993 )
2018
3
Multi-institutional study of peritoneal sarcomatosis from uterine sarcoma treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. ( 28967566 )
2017
4
Cytoreductive Surgery plus Hyperthermic Intraperitoneal Chemotherapy for Management of Peritoneal Sarcomatosis: A Preliminary Single-Center Experience from Saudi Arabia. ( 27212941 )
2016
5
Long-Term Survival in a Patient With Abdominal Sarcomatosis From Uterine Leiomyosarcoma: Role of Repeated Laparoscopic Surgery in Treatment and Follow-Up. ( 27234428 )
2016
6
Locoregional treatment of peritoneal sarcomatosis A single-centre experience. ( 27680058 )
2016
7
Peritoneal sarcomatosis: site of origin for the establishment of an in vitro and in vivo cell line model to study therapeutic resistance in dedifferentiated liposarcoma. ( 26373732 )
2015
8
Intraperitoneal bleomycin for sarcomatosis-related malignant ascites: Prolonged symptom relief. ( 25833195 )
2015
9
Differences in CT features of peritoneal carcinomatosis, sarcomatosis, and lymphomatosis: Retrospective analysis of 122 cases at a tertiary cancer institution. ( 25308238 )
2014
10
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in sarcomatosis from gastrointestinal stromal tumor. ( 25197876 )
2014
11
Sclerosing epithelioid fibrosarcoma presenting as intraabdominal sarcomatosis with a novel EWSR1-CREB3L1 gene fusion. ( 25123073 )
2014
12
Aggressive locoregional management of recurrent peritoneal sarcomatosis. ( 23386388 )
2013
13
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with peritoneal sarcomatosis: long-term outcome from a single institution experience. ( 24023339 )
2013
14
A comparison between patients with gastrointestinal stromal tumours diagnosed with isolated liver metastases and liver metastases plus sarcomatosis. ( 23458233 )
2013
15
Peritoneal lymphomatosis: CT and PET/CT findings and how to differentiate between carcinomatosis and sarcomatosis. ( 23598428 )
2013
16
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in peritoneal sarcomatosis. ( 23711273 )
2013
17
Peritoneal sarcomatosis in pediatric malignancies. ( 23002005 )
2013
18
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal sarcomatosis. ( 22302269 )
2012
19
Peritoneal sarcomatosis associated with telemetry implants in Sprague Dawley CD rats: a review of eight cases. ( 22083584 )
2012
20
Toxicity of hyperthermic intraperitoneal chemotherapy (HIPEC) in pediatric patients with sarcomatosis/carcinomatosis: early experience and phase 1 results. ( 22492588 )
2012
21
Systematic review on the efficacy of multimodal treatment of sarcomatosis with cytoreduction and intraperitoneal chemotherapy. ( 20697824 )
2011
22
Peritoneal sarcomatosis versus peritoneal carcinomatosis: imaging findings at MDCT. ( 20729420 )
2010
23
Peritoneal sarcomatosis: is there a subset of patients who may benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy? ( 20585874 )
2010
24
Fatal abdominal sarcomatosis secondary to gastrointestinal stromal tumor with bland histology. ( 19882063 )
2009
25
Pulmonary lymphangitic sarcomatosis and a review of the literature. ( 18506585 )
2009
26
Subgroup J avian leukosis virus-induced histiocytic sarcomatosis occurs only in persistently viremic but not immunotolerized meat-type chickens. ( 19261641 )
2009
27
Gigantic fetal tonsillar sarcomatosis. ( 18504389 )
2008
28
The consensus statement on the locoregional treatment of abdominal sarcomatosis. ( 18726899 )
2008
29
Toxicity and outcomes associated with surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with sarcomatosis. ( 17541691 )
2007
30
A phase II trial of intraperitoneal photodynamic therapy for patients with peritoneal carcinomatosis and sarcomatosis. ( 16638861 )
2006
31
Evaluation of intracavitary mitoxantrone and carboplatin for treatment of carcinomatosis, sarcomatosis and mesothelioma, with or without malignant effusions: A retrospective analysis of 12 cases (1997-2002)*. ( 19754772 )
2005
32
Randomized trial of cytoreduction followed by intraperitoneal chemotherapy versus cytoreduction alone in patients with peritoneal sarcomatosis. ( 15975759 )
2005
33
Primary leptomeningeal sarcomatosis; a pathology proven case with challenging MRI and clinical findings. ( 15015662 )
2004
34
Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients. ( 15269134 )
2004
35
Patterns of recurrence in patients treated with photodynamic therapy for intraperitoneal carcinomatosis and sarcomatosis. ( 14767557 )
2004
36
Hyperthermic intraperitoneal intraoperative chemotherapy after cytoreductive surgery for the treatment of abdominal sarcomatosis: clinical outcome and prognostic factors in 60 consecutive patients. ( 15112276 )
2004
37
Secondary leptomeningeal sarcomatosis. ( 15504072 )
2004
38
Quantitative prognostic indicators of peritoneal surface malignancy: carcinomatosis, sarcomatosis, and peritoneal mesothelioma. ( 14567023 )
2003
39
Tumor volume as a prognostic factor for sarcomatosis. ( 12015769 )
2002
40
Cytoreduction and intraperitoneal chemotherapy for the management of peritoneal carcinomatosis, sarcomatosis and mesothelioma. ( 11869020 )
2002
41
Abdominal and pelvic CT for detection and volume assessment of peritoneal sarcomatosis. ( 12195759 )
2002
42
Preliminary report of photodynamic therapy for intraperitoneal sarcomatosis. ( 11314943 )
2001
43
Multimodal treatment of peritoneal carcinomatosis and sarcomatosis. ( 11289746 )
2001
44
Hyperthermic intraoperative intraperitoneal chemotherapy for peritoneal carcinomatosis and sarcomatosis using a cardioplegia heat exchanger and a two-pump system: a case report. ( 11131220 )
2000
45
Pulmonary lymphangitic sarcomatosis from cutaneous angiosarcoma: an unusual presentation of diffuse interstitial lung disease. ( 10770568 )
2000
46
Melanotic peritoneal sarcomatosis originating from clear cell sarcoma. ( 10504528 )
1999
47
Clear cell sarcoma of the abdominal wall with peritoneal sarcomatosis: CT features. ( 10525863 )
1999
48
Intraperitoneal chemotherapy and cytoreductive surgery for the prevention and treatment of peritoneal carcinomatosis and sarcomatosis. ( 9548609 )
1998
49
A low incidence of histiocytic sarcomatosis associated with infection of chickens with the HPRS-103 strain of subgroup J avian leukosis virus. ( 9454931 )
1997
50
Classics in cytology. VIII: Diffuse meningeal sarcomatosis with invasion of the spinal cord and the spinal roots. Positive cytological results, especially of the cerebrospinal fluid. 1904. ( 9218908 )
1997

Variations for Sarcomatosis

Expression for Sarcomatosis

Search GEO for disease gene expression data for Sarcomatosis.

Pathways for Sarcomatosis

Pathways related to Sarcomatosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.14 ATF1 CREB3L1
2 11.07 ATF1 EWSR1 WT1
3 10.75 ATF1 CREB3L1

GO Terms for Sarcomatosis

Biological processes related to Sarcomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.46 ATF1 CREB3L1 EWSR1 WT1
2 transcription, DNA-templated GO:0006351 9.26 ATF1 CREB3L1 EWSR1 WT1
3 transcription by RNA polymerase II GO:0006366 8.8 ATF1 CREB3L1 WT1

Molecular functions related to Sarcomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0001228 8.62 ATF1 CREB3L1

Sources for Sarcomatosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....