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MCID: SCB001
MIFTS: 50

Scabies

Categories: Infectious diseases, Mental diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Scabies

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MalaCards integrated aliases for Scabies:

Name: Scabies 12 74 42 3 44 15 71 32
Infestation by Sarcoptes Scabiei Var Hominis 12
Infestation by Sarcoptes Scabiei 12
Sarcoptic Itch 12

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Skin diseases Mental diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:8295
ICD9CM 34 133.0
MeSH 44 D012532
NCIt 50 C34998
SNOMED-CT 67 266224002
ICD10 32 B86
UMLS 71 C0036262
Sources

Summaries for Scabies

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MedlinePlus : 42 Scabies is an itchy skin condition caused by the microscopic mite Sarcoptes scabei. It is common all over the world, and can affect anyone. Scabies spreads quickly in crowded conditions where there is frequent skin-to-skin contact between people. Hospitals, child-care centers, and nursing homes are examples. Scabies can easily infect sex partners and other household members. Sharing clothes, towels, and bedding can sometimes spread scabies. This can happen much more easily when the infested person has crusted scabies. You cannot get scabies from a pet. Pets get a different mite infection called mange. Symptoms are Pimple-like irritations or a rash Intense itching, especially at night Sores caused by scratching Your health care provider diagnoses scabies by looking at the skin rash and finding burrows in the skin. Several lotions are available to treat scabies. The infected person's clothes, bedding and towels should be washed in hot water and dried in a hot dryer. Treatment is also recommended for household members and sexual partners. Centers for Disease Control and Prevention

MalaCards based summary : Scabies, also known as infestation by sarcoptes scabiei var hominis, is related to norwegian scabies and hypereosinophilic syndrome, and has symptoms including fever, pruritus and exanthema. An important gene associated with Scabies is IL10 (Interleukin 10), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Azithromycin and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and spinal cord, and related phenotype is immune system.

Disease Ontology : 12 A mite infestation that is a contagious ectoparasite skin infection caused by human itch mite Sarcoptes scabiei type hominis, which burrows into the upper layer of the skin but never below the stratum corneum causing severe itching and a rash found on the hands, folds of the wrist, elbow or knee, penis, breast, and shoulder blades.

CDC : 3 Scabies is an infestation of the skin by the human itch mite (Sarcoptes scabiei var. hominis). The microscopic scabies mite burrows into the upper layer of the skin where it lives and lays its eggs. The most common symptoms of scabies are intense itching and a pimple-like skin rash. The scabies mite usually is spread by direct, prolonged, skin-to-skin contact with a person who has scabies. Scabies is found worldwide and affects people of all races and social classes. Scabies can spread rapidly under crowded conditions where close body and skin contact is frequent. Institutions such as nursing homes, extended-care facilities, and prisons are often sites of scabies outbreaks. Child-care facilities also are a common site of scabies infestations.

Wikipedia : 74 Scabies (also known as the seven-year itch) is a contagious skin infestation by the mite Sarcoptes... more...

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Related Diseases for Scabies

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Diseases related to Scabies via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 529)
# Related Disease Score Top Affiliating Genes
1 norwegian scabies 32.5 CD4 AADACL3
2 hypereosinophilic syndrome 30.7 IL10 CXCL8 CCL11
3 pustulosis of palm and sole 30.7 CXCL8 CCR6
4 pyoderma 30.7 CXCL8 CSF3 CCR6
5 rheumatic fever 30.6 MBL2 IL1A IL10
6 exanthem 30.1 IL10 CXCL8 CSF3 CD4 CCR6
7 chronic graft versus host disease 30.1 IL1A IL10
8 irritant dermatitis 30.1 IL31 IL1A CXCL8
9 mite infestation 30.1 IL31 CD4 AADACL3
10 dermatitis herpetiformis 30.0 IL31 IL10 CXCL8 CCL11
11 candidiasis 30.0 MBL2 IL10 CXCL8
12 acquired immunodeficiency syndrome 30.0 IL10 GSTM1 CD4 CCR6
13 dermatophytosis 30.0 CD4 CCR6
14 leprosy 3 29.9 IL10 CXCL8 CD4 CCR6
15 endocarditis 29.9 IL1A IL10 CXCL8
16 tinea corporis 29.9 IL31 AADACL3
17 interstitial lung disease 29.8 IL1A IL10 CXCL8
18 severe acute respiratory syndrome 29.7 MBL2 IL10 CXCL8
19 cellulitis 29.7 CSF3 CD4 CCR6
20 osteomyelitis 29.7 IL1A IL10 CXCL8 CSF3
21 human immunodeficiency virus type 1 29.7 IL10 CFP CD4 CCL11
22 disease by infectious agent 29.7 MBL2 IL10 CD4 CCR6
23 skin disease 29.7 IL31 IL1A IL10 CXCL8 CD4 CCR6
24 autoimmune disease 29.6 MBL2 IL1A IL10 CXCL8 CCR6
25 chickenpox 29.6 IL10 CD4 CCR6
26 rosacea 29.6 GSTM1 CXCL8 CCR6
27 bacterial vaginosis 29.6 MBL2 IL1A IL10 CXCL8
28 pyomyositis 29.6 CSF3 CD4
29 severe congenital neutropenia 29.5 KITLG IL1A CXCL8 CSF3
30 hyper ige syndrome 29.5 IL10 CXCL8 CCR6 CCL11
31 tungiasis 29.5 IL10 CXCL8 CD4
32 urethritis 29.5 IL10 CXCL8 CD4
33 immune deficiency disease 29.3 MBL2 IL1A IL10 CD4 CCR6
34 lung disease 29.3 MBL2 IL1A IL10 CXCL8 CSF3
35 psoriasis 29.3 IL31 IL1A IL10 CXCL8 CD4 CCR6
36 dermatitis 29.3 IL31 IL1A IL10 CXCL8 CD4 CCR6
37 genital herpes 29.3 IL10 CD4 CCR6
38 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 29.3 IL10 CD4 CCR6
39 herpes zoster 29.2 IL10 CD4 CCR6
40 folliculitis 29.2 CD4 CCR6 CCL11
41 neutropenia 29.2 MBL2 KITLG IL1A IL10 CXCL8 CSF3
42 pneumocystosis 29.2 CSF3 CD4 CCR6
43 contact dermatitis 29.2 IL31 IL1A IL10 CXCL8 CD4 CCR6
44 chronic mucocutaneous candidiasis 29.2 IL10 CD4 CCR6
45 allergic contact dermatitis 29.1 IL31 IL10 CXCL8 CD4 CCR6
46 immunoglobulin alpha deficiency 29.1 MBL2 CD4 CCR6
47 lymphadenitis 29.1 IL10 CXCL8 CD4 CCR6
48 parasitic helminthiasis infectious disease 29.1 IL10 CD4 CCR6 CCL11
49 myelodysplastic syndrome 29.0 KITLG IL1A IL10 GSTM1 CXCL8 CSF3
50 bacterial infectious disease 29.0 MBL2 IL1A IL10 CXCL8 CSF3 CFP

Comorbidity relations with Scabies via Phenotypic Disease Network (PDN):


Acute Cystitis Alzheimer Disease
Decubitus Ulcer Deficiency Anemia
Heart Disease Protein-Energy Malnutrition
Schizophreniform Disorder

Graphical network of the top 20 diseases related to Scabies:



Diseases related to Scabies
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Symptoms & Phenotypes for Scabies

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UMLS symptoms related to Scabies:


fever, pruritus, exanthema

MGI Mouse Phenotypes related to Scabies:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.28 CCL11 CCR6 CD4 CFP CSF3 IL10
Sources

Drugs & Therapeutics for Scabies

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Drugs for Scabies (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4 83905-01-5 55185 447043
2 Anti-Bacterial Agents Phase 4
3
Diethylcarbamazine Approved, Investigational, Vet_approved Phase 3 90-89-1 3052
4
Albendazole Approved, Vet_approved Phase 3 54965-21-8 2082
5
Malathion Approved, Investigational Phase 3 121-75-5 4004
6
Ivermectin Approved, Investigational, Vet_approved Phase 3 70288-86-7 6474909
7
Permethrin Approved, Investigational Phase 3 52645-53-1 40326
8 Anthelmintics Phase 3
9 Neurotransmitter Agents Phase 3
10 Cholinesterase Inhibitors Phase 3
11 Cholinergic Agents Phase 3
12 Antimitotic Agents Phase 3
13 Antiprotozoal Agents Phase 3
14 Tubulin Modulators Phase 3
15 Anti-Infective Agents Phase 3
16 Antiparasitic Agents Phase 3
17 Emollients Phase 3
18
Benzocaine Approved, Investigational Phase 2 1994-09-7, 94-09-7 2337
19
tannic acid Approved Phase 2 1401-55-4
20
Fennel Approved, Experimental Phase 2
21 Milbemycin Phase 2
22 English Lavender Phase 2
23 Liver Extracts
24 Vaccines
25 Dermatologic Agents

Interventional clinical trials:

(show all 24)
# Name Status NCT ID Phase Drugs
1 Impact of Combined Azithromycin and Ivermectin Mass Drug Administration for Yaws and Scabies - Impact on Impetigo and Skin Microbiology Completed NCT02775617 Phase 4 Ivermectin;Azithromycin;Permethrin
2 A Randomized Controlled Trial Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon Completed NCT04205669 Phase 4 Benzyl Benzoate 25% Topical Application Lotion
3 Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children: a Cluster Multicenter Randomized Trial Unknown status NCT02407782 Phase 3 Ivermectin;Permethrin
4 A Randomized, Double-Blind, Parallel-Design, Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% to Elimiteâ„¢ Cream 5% in the Treatment of Scabies Completed NCT02572986 Phase 3 Permethrin
5 A Double Blind, Two Arm, Multicenter, Randomized, Parallel Group, Bioequivalence Study With Clinical Endpoints to Evaluate the Safety and Therapeutic Equivalence of Permethrin Cream 5% & Elimiteâ„¢ in Subjects With Scabies Completed NCT03973775 Phase 3 Permethrin Cream 5%
6 A Randomized, Double-Blind, Parallel-Design, Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% (Encube Ethicals) Compared to Elimiteâ„¢ Cream (Permethrin) 5% (Prestium Pharma, Inc.) in the Treatment of Scabies Completed NCT03178942 Phase 3 Permethrin Cream, 5%;Elimiteâ„¢ Cream (permethrin) 5%
7 A Phase 3, Randomized, Double Blind, Placebo-Controlled Study to Assess the Safety, Efficacy and Pharmacokinetics of Natrobaâ„¢ (Spinosad) for the Treatment of Scabies Completed NCT02485717 Phase 3 spinosad topical suspension, 0.9%
8 A Phase 3, Randomized, Double Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Natrobaâ„¢ (Spinosad) for the Treatment of Scabies Completed NCT02485704 Phase 3 spinosad topical suspension, 0.9%
9 A Multi-center, Double-blind, Randomized, Parallel-group Study Comparing Permethrin Cream, 5% With Elimiteâ„¢ in Patients With Active Scabies. Completed NCT02978508 Phase 3 Permethrin Cream, 5%;Elimite
10 Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands Completed NCT03236168 Phase 3 Ivermectin;Permethrin 5%;Malathion Shampoo 0.5%
11 A Cluster Randomised Trial of the Safety of Co-Administration of IDA (Ivermectin, Diethylcarbamazine and Albendazole) & Azithromycin for Integrated Treatment of Neglected Tropical Diseases Completed NCT03676140 Phase 3 Albendazole on Day 1;Ivermectin on Day 1;Diethylcarbamazine on day 1;Azithromycin on Day 1;Azithromycin on Day 8
12 A Randomized Controlled Double-blind Trial Assessing the Efficacy of a 400µg/kg Ivermectin /5% Permethrin / Emollient Cream Regimen in Patients With Crusted Scabies as Compared to a 200µg/kg Ivermectin /5% Permethrin /Emollient Cream Regimen Recruiting NCT02841215 Phase 3 Ivermectin 200 µg/kg;Ivermectin 400 µg/kg
13 A Multicenter, Randomized, Double-Blind, Parallel Group Comparison Study of the Safety and Efficacy of Permethrin Foam, 5% Versus Permethrin Foam, 4% Versus Vehicle in Subjects With Sarcoptes Scabiei Completed NCT02094716 Phase 2 Permethrin Foam 4%;Permethrin Foam 5%;Vehicle Foam
14 A Randomised, Double Blind, Double Dummy Study to Compare the Efficacy and Safety of a Single Administration of Ivermectin to a Single Administration of Permethrin for the Treatment of Scabies Completed NCT00262418 Phase 2 Administration of ivermectin or permethrin
15 A Phase II, Randomized, Double-blind, Parallel Group Dose Finding Study of Single Oral Doses of Moxidectin in Adults With Scabies Recruiting NCT03905265 Phase 2 Moxidectin Oral Product
16 A Randomised, Double-blind, Placebo-controlled Trial to Assess the Safety, Pharmacokinetics, and Efficacy of Escalating Doses of Oral Ivermectin in Scabies Infected Children Weighing 5 to Less Than 15 Kilograms Not yet recruiting NCT04332068 Phase 2 Oral ivermectin;Permethrin Cream
17 Community Based Safety Study of 2-drug (Diethylcarbamazine and Albendazole) Versus 3-drug (Ivermectin, Diethylcarbamazine and Albendazole) Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji Completed NCT03177993 3 drug dose - IDA;3 drug dose - IDA with second dose of ivermectin;2 drug dose - DA
18 Veron Scabies Education and Eradication Program Completed NCT00604084 Ivermectin;Permethrin 5% lotion
19 PCR (Polymerase Chain Reaction) Assay for Diagnosis of Sarcoptes Scabiei Completed NCT02254564
20 East Arnhem Healthy Skin Project: A Regional Collaboration to Reduce Scabies, Skin Sores and Associated Chronic Diseases, Including Rheumatic Fever and Renal Disease, Among Australian Aboriginal Communities Completed NCT00884728
21 The Epidemiology of Group A Streptococcal Infections in Fiji (Fiji GrASP) Part 3: The Incidence of Group A Streptococcal Pharyngitis and the Prevalence of Pyoderma and Scabies in School Children in Fiji, and Establishing Immunologic Correlates of Protection for a J8 Vaccine Completed NCT00284882
22 The Epidemiology of Group A Streptococcal Infections in Fiji (Fiji GrASP) Part 1: The Prevalence of Rheumatic Heart Disease, Pyoderma and Scabies in School Children in Fiji Completed NCT00284843
23 The Epidemiology of Group A Streptococcal Infections in Fiji (Fiji GrASP) - Part 4 -The Prevalence of Group A Streptococcal Pyoderma and Scabies in Infants in Fiji Completed NCT00436891
24 Contagious Itch, Disgust and Empathy in Patients and Medical Staff Recruiting NCT04557644

Search NIH Clinical Center for Scabies

Inferred drug relations via UMLS 71 / NDF-RT 51 :


ANISE OIL/CORIANDER OIL/LEMON OIL/ORANGE OIL
crotamiton
Ivermectin
Lindane
Permethrin
Piperonyl Butoxide

Cochrane evidence based reviews: scabies

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Genetic Tests for Scabies

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Anatomical Context for Scabies

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MalaCards organs/tissues related to Scabies:

40
Skin, Liver, Spinal Cord, Bone Marrow, T Cells, Endothelial, Thymus
Sources

Publications for Scabies

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Articles related to Scabies:

(show top 50) (show all 3637)
# Title Authors PMID Year
1
Case Report: Scabies Invading Gingival Tissue. 61 42
33258442 2021
2
Lepromatous Leprosy with Crusted Scabies. 42 61
33269674 2020
3
Disseminated crusted scabies in an elderly patient. 42 61
33338113 2020
4
Estimating the global burden of scabies: what else do we need? 61
32358799 2021
5
[Parasitoses in childhood]. 61
33599802 2021
6
Scabies outbreak in Turkey in 2018-2019. 61
33539599 2021
7
[Scabies-Renaissance of an ectoparasite infection : Diagnosis and therapy-How to proceed in practice]. 61
33346858 2021
8
Predators in northern Germany are reservoirs for parasites of One Health concern. 61
33547507 2021
9
Scabies-induced lichen simplex chronicus misdiagnosed as psychogenic pruritus: a case report. 61
33593424 2021
10
A novel deletion mutation in the ATP2C1 gene in a case of generalized Hailey-Hailey disease possibly aggravated by scabies infection. 61
33580912 2021
11
[Palmoplantar dermatoses in children]. 61
33580281 2021
12
Public Interest in Dermatologic Symptoms, Conditions, Treatments, and Procedures during the COVID-19 Pandemic: Insights from Google Trends. 61
33595849 2021
13
[Usefulness of dermoscopy in the diagnosis of scabies]. 61
32811754 2021
14
The ink test for scabies. 61
33446379 2021
15
In vivo reflectance confocal microscopy for the diagnosis of scabies. 61
33495171 2021
16
Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies. 61
33450958 2021
17
Common sites for the gray-edged line sign in patients with scabies. 61
33458847 2021
18
Oral ivermectin for a scabies outbreak in a long-term-care facility: Potential value in preventing COVID-19 and associated mortality? 61
33454964 2021
19
Treatment practices in the management of scabies in infants younger than two months. 61
33486822 2021
20
Management of an outbreak of invasive Kingella kingae skeletal infections in a day care center. 61
33309121 2021
21
Case series of elderly patients with scabies topically applied with ivermectin via whole-body bathing. 61
33410137 2021
22
Review of Scabies Infestation and Selected Common Cutaneous Infections. 61
33386302 2021
23
Scabies-infested pregnant women: A critical therapeutic challenge. 61
33411710 2021
24
Itch in Scabies-What Do We Know? 61
33598472 2021
25
Prevalence of scratching during examination among patients with scabies and among patients with other pruritic dermatoses. 61
33252818 2021
26
A unique group of scabies mite pseudoproteases promotes cutaneous blood coagulation and delays plasmin-induced fibrinolysis. 61
33406071 2021
27
Clinical, Parasitological, and Serological Follow-Up of Dogs with Sarcoptic Mange Treated Orally with Lotilaner. 61
33575060 2021
28
A review of ethnomedicinal uses of shea butter for dermatoses in Sub-Saharan Africa. 61
33480103 2021
29
Scabies with Secondary Infection Resembling Kerion-Type Tinea Capitis. 61
33488115 2021
30
Live-interactive teledermatology program in Taiwan: One-year experience serving a district hospital in rural Taitung County. 61
32563581 2021
31
A comprehensive entomological survey and evaluation of the efficacy of different therapies on a suspected delusional parasitosis case. 61
33174366 2021
32
[Noninvasive diagnostic imaging in pediatric skin lesions]. 61
33471130 2021
33
Antimycobacterial, Cytotoxic, and Antioxidant Activities of Abietane Diterpenoids Isolated from Plectranthus madagascariensis. 61
33477744 2021
34
Detailed analysis of the fatty acid composition of six plant-pathogenic bacteria. 61
33373896 2021
35
Ivermectin, a potential anticancer drug derived from an antiparasitic drug. 61
32971268 2021
36
Health Disparities among Australia's Remote-Dwelling Aboriginal People: A Report from 2020. 61
33241298 2021
37
Scabies involving palms in older children and adults: a changing scenario. 61
33393684 2021
38
Scabies: Diagnostic and Therapeutic Update. 61
32998532 2021
39
Scabies outbreak during home confinement due to the SARS-CoV-2 pandemic. 61
32810303 2020
40
Scabies coexisting with other dermatoses: the importance of recognizing multiple pathologies in resource-poor settings. 61
32640041 2020
41
Fluorescence advanced videodermatoscopy for the rapid and safe diagnosis of misdiagnosed scabies. 61
33300166 2020
42
The Incidence of Scabies and Head Lice and Their Associated Risk Factors among Displaced People in Cham Mishko Camp, Zakho City, Duhok Province, Iraq. 61
33574874 2020
43
Serum thymus and activation-regulated chemokine levels before and after treatment for pruritic scabies. 61
32484992 2020
44
Molecular drug targets for scabies: a medicinal chemistry perspective. 61
33243012 2020
45
Population pharmacokinetics of ivermectin for the treatment of scabies in Indigenous Australian children. 61
33284799 2020
46
Community perspectives on scabies, impetigo and mass drug administration in Fiji: A qualitative study. 61
33275592 2020
47
Development and efficacy of a nested real-time quantitative polymerase chain reaction to identify the cytochrome c oxidase subunit 1 gene of Sarcoptes scabiei var. hominis for diagnosis and monitoring of ordinary scabies. 61
32594512 2020
48
A scabies outbreak in the North East Region of Ghana: The necessity for prompt intervention. 61
33351803 2020
49
An extraordinary outbreak of scabies in Turkey. 61
32491243 2020
50
An Increasing Scabies Incidence in Croatia: A Call for Coordinated Action Among Dermatologists, Physicians and Epidemiologists. 61
33133283 2020
Sources

Variations for Scabies

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Expression for Scabies

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Search GEO for disease gene expression data for Scabies.
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Pathways for Scabies

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Pathways related to Scabies according to GeneCards Suite gene sharing:

(show all 23)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 65
Show member pathways
 13.74 MBL2 KITLG IL31 IL1A IL10 CXCL8
2
ERK Signaling 63
Show member pathways
 13.65 KITLG IL1A IL10 CXCL8 CSF3 CD4
3
PEDF Induced Signaling 63
Show member pathways
 13.49 IL31 IL1A IL10 CXCL8 CSF3 CD4
4
Akt Signaling 63
Show member pathways
 13.12 KITLG IL1A IL10 CXCL8 CSF3 CD4
5
Cytokine Signaling in Immune system 65
Show member pathways
 13.03 KITLG IL31 IL1A IL10 CXCL8 CSF3
6
PAK Pathway 63
Show member pathways
 12.93 KITLG IL1A IL10 CXCL8 CSF3 CD4
7
Allograft rejection 36 1
Show member pathways
 12.7 IL1A IL10 CXCL8 CD4 CCL11
8
Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions 64
Show member pathways
 12.17 IL10 CXCL8 CCR6 CCL11
9
Immune response IFN alpha/beta signaling pathway 23
Show member pathways
 12.12 KITLG IL1A IL10 CXCL8
10
Yersinia infection 36
11.92 IL10 CXCL8 CD4
11
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.86 KITLG IL10 CSF3 CD4
12
Interleukin-4 and 13 signaling 65
11.84 IL1A IL10 CXCL8 CCL11
13
Hematopoietic cell lineage 36
11.73 KITLG IL1A CSF3 CD4
14
Innate Lymphoid Cell Differentiation Pathways 64
11.68 IL10 CD4 CCR6
15
C-MYB transcription factor network 1
11.66 KITLG GSTM1 CD4
16
Pertussis 36
11.64 IL1A IL10 CXCL8
17
Lung fibrosis 1
11.54 CXCL8 CSF3 CCL11
18
Malaria 36
11.4 IL10 CXCL8 CSF3
19
Hematopoietic Stem Cell Differentiation 1
11.37 KITLG IL1A CSF3
20
Interleukin-10 signaling 65
11.15 IL1A IL10 CXCL8 CSF3
21
Th2 Differentiation Pathway 64
10.92 IL31 IL10 CD4 CCL11
22
G-protein signaling_Rap2B regulation pathway 23
10.84 KITLG IL1A IL10 CXCL8 CSF3 CCL11
23
Cytokines and Inflammatory Response 1
10.39 IL1A IL10 CSF3 CD4
Sources

GO Terms for Scabies

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Cellular components related to Scabies according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 MBL2 KITLG IL31 IL1A IL10 CXCL8
2 extracellular space GO:0005615 9.28 MBL2 KITLG IL31 IL1A IL10 CXCL8

Biological processes related to Scabies according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.98 KITLG IL10 CXCL8 CSF3 CD4 CCR6
2 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.58 KITLG CSF3 CD4
3 chemokine-mediated signaling pathway GO:0070098 9.5 CXCL8 CCR6 CCL11
4 cytokine-mediated signaling pathway GO:0019221 9.5 IL31 IL1A IL10 CXCL8 CSF3 CD4
5 cellular response to lipopolysaccharide GO:0071222 9.46 IL1A IL10 CXCL8 CSF3
6 response to molecule of bacterial origin GO:0002237 9.37 IL10 CXCL8
7 ectopic germ cell programmed cell death GO:0035234 9.26 KITLG IL1A
8 immune response GO:0006955 9.23 IL1A IL10 CXCL8 CSF3 CFP CD4

Molecular functions related to Scabies according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.17 KITLG IL31 IL1A IL10 CXCL8 CSF3
Sources

Sources for Scabies

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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