MCID: SCB001
MIFTS: 50

Scabies

Categories: Infectious diseases, Skin diseases
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Aliases & Classifications for Scabies

MalaCards integrated aliases for Scabies:

Name: Scabies 11 75 41 2 43 14 71 31 33
Sarcoptic Itch 11 33
Infestation by Sarcoptes Scabiei Var. Hominis 33
Infestation by Sarcoptes Scabiei Var Hominis 11
Infestation by Sarcoptes Scabiei 11

Classifications:



External Ids:

Disease Ontology 11 DOID:8295
ICD9CM 34 133.0
MeSH 43 D012532
NCIt 49 C34998
SNOMED-CT 68 266224002
ICD10 31 B86
ICD11 33 876005123
UMLS 71 C0036262

Summaries for Scabies

MedlinePlus: 41 Scabies is an itchy skin condition caused by the microscopic mite Sarcoptes scabei. It is common all over the world, and can affect anyone. Scabies spreads quickly in crowded conditions where there is frequent skin-to-skin contact between people. Hospitals, child-care centers, and nursing homes are examples. Scabies can easily infect sex partners and other household members. Sharing clothes, towels, and bedding can sometimes spread scabies. This can happen much more easily when the infested person has crusted scabies. You cannot get scabies from a pet. Pets get a different mite infection called mange. Symptoms are: Pimple-like irritations or a rash Intense itching, especially at night Sores caused by scratching Your health care provider diagnoses scabies by looking at the skin rash and finding burrows in the skin. Several lotions are available to treat scabies. The infected person's clothes, bedding and towels should be washed in hot water and dried in a hot dryer. Treatment is also recommended for household members and sexual partners. Centers for Disease Control and Prevention

MalaCards based summary: Scabies, also known as sarcoptic itch, is related to norwegian scabies and exanthem, and has symptoms including fever, pruritus and exanthema. An important gene associated with Scabies is MBL2 (Mannose Binding Lectin 2), and among its related pathways/superpathways are Innate Immune System and PAK Pathway. The drugs Azithromycin and Ivermectin have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and liver, and related phenotype is immune system.

CDC: 2 Scabies is an infestation of the skin by the human itch mite (Sarcoptes scabiei var. hominis). The microscopic scabies mite burrows into the upper layer of the skin where it lives and lays its eggs. The most common symptoms of scabies are intense itching and a pimple-like skin rash. The scabies mite usually is spread by direct, prolonged, skin-to-skin contact with a person who has scabies. Scabies is found worldwide and affects people of all races and social classes. Scabies can spread rapidly under crowded conditions where close body and skin contact is frequent. Institutions such as nursing homes, extended-care facilities, and prisons are often sites of scabies outbreaks. Child-care facilities also are a common site of scabies infestations.

Disease Ontology: 11 A mite infestation that is a contagious ectoparasite skin infection caused by human itch mite Sarcoptes scabiei type hominis, which burrows into the upper layer of the skin but never below the stratum corneum causing severe itching and a rash found on the hands, folds of the wrist, elbow or knee, penis, breast, and shoulder blades.

Wikipedia: 75 Scabies (/ˈskeɪbiːz, ˈskeɪbiiːz/; also known as the seven-year itch) is a contagious skin infestation by... more...

Related Diseases for Scabies

Diseases related to Scabies via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 677)
# Related Disease Score Top Affiliating Genes
1 norwegian scabies 32.3 IL5 IL13 CD8A CD4 AADACL3
2 exanthem 30.4 IL4 CD8A CD4 CCR6
3 langerhans cell histiocytosis 30.3 TNFRSF8 CD1E CCR6
4 adult t-cell leukemia/lymphoma 30.2 TNFRSF8 CD8A CD4 CCR6
5 tinea corporis 30.2 FLG CD4
6 mastocytosis, cutaneous 30.2 TNFRSF8 IL31 CD1E
7 histiocytosis 30.2 TNFRSF8 IL4 CCR6
8 syphilis 30.1 CD8A CD4 CCR6
9 epidermolysis bullosa 30.1 FLG DST COL17A1
10 bullous pemphigoid 30.1 IL5 IL4 DST COL17A1
11 cellulitis 30.0 IL5 CD8A CD4 CCR6
12 thrombocytopenia due to platelet alloimmunization 30.0 CD8A CD4 CCR6
13 thrombocytopenic purpura, autoimmune 30.0 CD8A CD4 CCR6
14 granuloma annulare 30.0 CD8A CD4 CD1E
15 giardiasis 30.0 STH CD8A CD4
16 t-cell acute lymphoblastic leukemia 29.9 TNFRSF8 IL5 CD8A CD4 CCR6
17 occupational dermatitis 29.9 IL31 FLG
18 bacterial vaginosis 29.9 MBL2 CD4 CCR6
19 dermatitis herpetiformis 29.9 IL5 IL4 IL31
20 pneumocystosis 29.9 CD8A CD4 CCR6
21 onchocerciasis 29.9 STH IL5 IL4 IL13
22 epidermolysis bullosa dystrophica 29.9 FLG DST COL17A1
23 seborrheic dermatitis 29.9 FLG CD4 CD1E CCR6
24 spinal cord disease 29.8 CD8A CD4 CCR6
25 dermatitis 29.8 IL5 IL4 IL31 IL13 FLG CCR6
26 histiocytoid hemangioma 29.8 TNFRSF8 IL5
27 ige responsiveness, atopic 29.8 IL5 IL4 IL13
28 urticaria 29.8 IL5 IL4 IL31 IL13 CD4
29 candidiasis 29.7 MBL2 IL5 IL4
30 filariasis 29.7 STH IL5 IL4 IL13 CD4
31 pityriasis rosea 29.7 CD8A CD4 CD1E
32 genital herpes 29.7 CD8A CD4 CCR6
33 bacterial sepsis 29.7 CD8A CD4 CCR6
34 epidermolysis bullosa simplex 29.6 FLG DST COL17A1
35 immunoglobulin alpha deficiency 29.6 MBL2 CD8A CD4 CCR6
36 pemphigoid 29.6 IL5 IL4 IL31 IL13 DST COL17A1
37 pemphigus 29.5 IL4 DST COL17A1
38 lepromatous leprosy 29.5 IL4 CD8A CD4 CCR6
39 pemphigus vulgaris, familial 29.5 DST COL17A1 CCR6
40 granulomatous dermatitis 29.5 CD8A CD4 CD1E
41 trachoma 29.5 STH MBL2 IL4
42 chickenpox 29.4 IL4 CD8A CD4 CCR6
43 herpes zoster 29.4 COL17A1 CD8A CD4 CCR6
44 t-cell adult acute lymphocytic leukemia 29.4 TNFRSF8 CD8A CD4 CCR6
45 mastocytosis 29.4 TNFRSF8 IL4 IL13
46 lichen planus 29.3 IL4 FLG DST COL17A1
47 filarial elephantiasis 29.3 STH IL5 IL4 IL13 CD8A CD4
48 aspergillosis 29.3 MBL2 IL5 IL4 CCR6
49 leishmaniasis 29.3 IL5 IL4 IL13
50 autoimmune disease 29.3 MBL2 IL5 IL4 IL13 COL17A1 CCR6

Comorbidity relations with Scabies via Phenotypic Disease Network (PDN):


Acute Cystitis Alzheimer Disease, Familial, 1
Decubitus Ulcer Deficiency Anemia
Heart Disease Protein-Energy Malnutrition
Schizophreniform Disorder

Graphical network of the top 20 diseases related to Scabies:



Diseases related to Scabies

Symptoms & Phenotypes for Scabies

UMLS symptoms related to Scabies:


fever; pruritus; exanthema

MGI Mouse Phenotypes related to Scabies:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.36 CCR6 CD4 CD8A CFP COL17A1 DST

Drugs & Therapeutics for Scabies

Drugs for Scabies (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4 83905-01-5 447043
2
Ivermectin Approved, Investigational, Vet_approved Phase 4 70288-86-7 9812710 6427057
3 Anti-Bacterial Agents Phase 4
4 Anti-Infective Agents Phase 4
5 Antiparasitic Agents Phase 4
6
Albendazole Approved, Vet_approved Phase 3 54965-21-8 2082
7
Diethylcarbamazine Approved, Investigational, Vet_approved Phase 3 90-89-1 3052
8
Malathion Approved, Investigational Phase 3 121-75-5 4004
9
Permethrin Approved, Investigational Phase 3 52645-53-1 40326
10
Artenimol Approved, Experimental, Investigational Phase 3 71939-50-9 540327
11
Piperaquine Approved, Experimental, Investigational Phase 3 4085-31-8
12 Anthelmintics Phase 3
13 Neurotransmitter Agents Phase 3
14 Cholinesterase Inhibitors Phase 3
15 Cholinergic Agents Phase 3
16 Antimitotic Agents Phase 3
17 Tubulin Modulators Phase 3
18 Emollients Phase 3
19 Antiprotozoal Agents Phase 3
20 Antimalarials Phase 3
21
Benzocaine Approved, Investigational Phase 2 1994-09-7, 94-09-7 2337
22
Tannic acid Approved Phase 2 1401-55-4 16129878 16129778
23
Moxidectin Approved, Investigational, Vet_approved Phase 2 113507-06-5 72728820
24
Fennel Approved, Experimental Phase 2
25 English Lavender Phase 2
26 Liver Extracts
27 Vaccines

Interventional clinical trials:

(show all 33)
# Name Status NCT ID Phase Drugs
1 A Randomized Controlled Trial Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon Completed NCT04205669 Phase 4 Benzyl Benzoate 25% Topical Application Lotion
2 Impact of Combined Azithromycin and Ivermectin Mass Drug Administration for Yaws and Scabies - Impact on Impetigo and Skin Microbiology Completed NCT02775617 Phase 4 Ivermectin;Azithromycin;Permethrin
3 A Single Treatment Pharmacokinetic and Safety Study of Natroba (Spinosad) Topical Suspension 0.9% w/w in Subjects 1 Month to 3 Years 11 Months of Age With an Active Scabies Infestation Recruiting NCT05310734 Phase 4 Spinosad Topical
4 Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study) Not yet recruiting NCT05500326 Phase 4 Ivermectin Tablets
5 Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children: a Cluster Multicenter Randomized Trial Unknown status NCT02407782 Phase 3 Ivermectin;Permethrin
6 A Multi-center, Double-blind, Randomized, Parallel-group Study Comparing Permethrin Cream, 5% With Elimite™ in Patients With Active Scabies. Completed NCT02978508 Phase 3 Permethrin Cream, 5%;Elimite
7 A Randomized, Double-Blind, Parallel-Design, Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% to Elimite™ Cream 5% in the Treatment of Scabies Completed NCT02572986 Phase 3 Permethrin
8 A Phase 3, Randomized, Double Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Natroba™ (Spinosad) for the Treatment of Scabies Completed NCT02485704 Phase 3 spinosad topical suspension, 0.9%
9 A Randomized, Double-Blind, Parallel-Design, Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% (Encube Ethicals) Compared to Elimite™ Cream (Permethrin) 5% (Prestium Pharma, Inc.) in the Treatment of Scabies Completed NCT03178942 Phase 3 Permethrin Cream, 5%;Elimite™ Cream (permethrin) 5%
10 A Phase 3, Randomized, Double Blind, Placebo-Controlled Study to Assess the Safety, Efficacy and Pharmacokinetics of Natroba™ (Spinosad) for the Treatment of Scabies Completed NCT02485717 Phase 3 spinosad topical suspension, 0.9%
11 Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands Completed NCT03236168 Phase 3 Ivermectin;Permethrin 5%;Malathion Shampoo 0.5%
12 A Double Blind, Two Arm, Multicenter, Randomized, Parallel Group, Bioequivalence Study With Clinical Endpoints to Evaluate the Safety and Therapeutic Equivalence of Permethrin Cream 5% & Elimite™ in Subjects With Scabies Completed NCT03973775 Phase 3 Permethrin Cream 5%
13 A Cluster Randomised Trial of the Safety of Co-Administration of IDA (Ivermectin, Diethylcarbamazine and Albendazole) & Azithromycin for Integrated Treatment of Neglected Tropical Diseases Completed NCT03676140 Phase 3 Albendazole on Day 1;Ivermectin on Day 1;Diethylcarbamazine on day 1;Azithromycin on Day 1;Azithromycin on Day 8
14 Prospective, Open-label, Multicenter, Initially Single-armed and in Case of Treatment Failure Subsequently Three-armed Randomized Clinical Trial of Phase III/IV Investigating the Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin) Recruiting NCT04814511 Phase 3 InfectoScab 5 % Creme;Permethrin 10 % Creme;Driponin 3 mg Tabletten
15 A Randomized Controlled Double-blind Trial Assessing the Efficacy of a 400µg/kg Ivermectin /5% Permethrin / Emollient Cream Regimen in Patients With Crusted Scabies as Compared to a 200µg/kg Ivermectin /5% Permethrin /Emollient Cream Regimen Recruiting NCT02841215 Phase 3 Ivermectin 200 µg/kg;Ivermectin 400 µg/kg
16 Adjunctive Ivermectin Mass Drug Administration for Malaria Control on the Bijagos Archipelago of Guinea Bissau: A Cluster-randomized Placebo-controlled Trial Recruiting NCT04844905 Phase 3 Ivermectin;Placebo;Dihydroartemisinin-piperaquine
17 A Phase II, Randomized, Double-blind, Parallel Group Dose Finding Study of Single Oral Doses of Moxidectin in Adults With Scabies Completed NCT03905265 Phase 2 Moxidectin Oral Product
18 A Randomised, Double Blind, Double Dummy Study to Compare the Efficacy and Safety of a Single Administration of Ivermectin to a Single Administration of Permethrin for the Treatment of Scabies Completed NCT00262418 Phase 2 Administration of ivermectin or permethrin
19 A Multicenter, Randomized, Double-Blind, Parallel Group Comparison Study of the Safety and Efficacy of Permethrin Foam, 5% Versus Permethrin Foam, 4% Versus Vehicle in Subjects With Sarcoptes Scabiei Completed NCT02094716 Phase 2 Permethrin Foam 4%;Permethrin Foam 5%;Vehicle Foam
20 A Randomised, Double-blind, Placebo-controlled Trial to Assess the Safety, Pharmacokinetics, and Efficacy of Escalating Doses of Oral Ivermectin in Scabies Infected Children Weighing 5 to Less Than 15 Kilograms Not yet recruiting NCT04332068 Phase 2 Oral ivermectin;Permethrin Cream
21 Comparative Study Between Topical Permethrin 5% and Oral Ivermectin for the Treatment of Scabies Completed NCT05362513 Phase 1 Ivermectin Tablets;Permethrin Cream
22 The Epidemiology of Group A Streptococcal Infections in Fiji (Fiji GrASP) - Part 4 -The Prevalence of Group A Streptococcal Pyoderma and Scabies in Infants in Fiji Completed NCT00436891
23 Veron Scabies Education and Eradication Program Completed NCT00604084 Ivermectin;Permethrin 5% lotion
24 Community Based Safety Study of 2-drug (Diethylcarbamazine and Albendazole) Versus 3-drug (Ivermectin, Diethylcarbamazine and Albendazole) Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji Completed NCT03177993 3 drug dose - IDA;3 drug dose - IDA with second dose of ivermectin;2 drug dose - DA
25 Better Disease Control by Multidrug Regimen in Scabies: A Randomized Controlled Trial Completed NCT05198947 Permethrin Lotion 5%;Permethrin Lotion 5% and Oral Ivermectin 200 mcg/kg
26 The Epidemiology of Group A Streptococcal Infections in Fiji (Fiji GrASP) Part 3: The Incidence of Group A Streptococcal Pharyngitis and the Prevalence of Pyoderma and Scabies in School Children in Fiji, and Establishing Immunologic Correlates of Protection for a J8 Vaccine Completed NCT00284882
27 The Epidemiology of Group A Streptococcal Infections in Fiji (Fiji GrASP) Part 1: The Prevalence of Rheumatic Heart Disease, Pyoderma and Scabies in School Children in Fiji Completed NCT00284843
28 East Arnhem Healthy Skin Project: A Regional Collaboration to Reduce Scabies, Skin Sores and Associated Chronic Diseases, Including Rheumatic Fever and Renal Disease, Among Australian Aboriginal Communities Completed NCT00884728
29 Efficacy and Side Effects of Blacksoap® as Adjuvant Therapy of Scabies: a Single-blind Randomized Control Trial Completed NCT05025696
30 PCR (Polymerase Chain Reaction) Assay for Diagnosis of Sarcoptes Scabiei Completed NCT02254564
31 Streptococcus Pyogenes Carriage Acquisition, Persistence and Transmission Dynamics Within Households in The Gambia: a Longitudinal Cohort Study Completed NCT05117528
32 Risk Factors for Treatment Failure of Scabies in Autochthonous Populations of French Guiana (GUYAGALE) Recruiting NCT04931680
33 Place of Hygiene in Scabies's Treatment in Populations in Precarious Situations Not yet recruiting NCT05271968

Search NIH Clinical Center for Scabies

Inferred drug relations via UMLS 71 / NDF-RT 50 :


ANISE OIL/CORIANDER OIL/LEMON OIL/ORANGE OIL
crotamiton
Ivermectin
Lindane
Permethrin
Piperonyl Butoxide

Cochrane evidence based reviews: scabies

Genetic Tests for Scabies

Anatomical Context for Scabies

Organs/tissues related to Scabies:

MalaCards : Skin, Breast, Liver, Heart, Spinal Cord, Bone Marrow, Kidney

Publications for Scabies

Articles related to Scabies:

(show top 50) (show all 3977)
# Title Authors PMID Year
1
Adjunctive Agent for Treating Scabies: In vitro Killing Activity of Permethrin and Tea Tree Oil on Sarcoptes scabiei Collected from Patients 62 41
36444410 2022
2
Contagious Itch, Disgust and Empathy in a Family with Scabies and their Treating Medical Staff: An Exploratory Study. 62 41
36281810 2022
3
Ivermectin mass drug administration for onchocerciasis elimination: can it reduce the prevalence of scabies in Ethiopia? 62 41
36156500 2022
4
Tropical parasitic itch in returned travellers and immigrants from endemic areas. 62
35793476 2022
5
[[Translated article]]Diagnosis and Clinical Characteristics of Scabies in a Tertiary Care Hospital During the SARS-CoV-2 Pandemic: A Descriptive Study. 62
36464010 2022
6
Proteomic analysis of Sarcoptes scabiei reveals that proteins differentially expressed between eggs and female adult stages are involved predominantly in genetic information processing, metabolism and/or host-parasite interactions. 62
36472966 2022
7
The genetic characteristics of Sarcoptes scabiei from Chinese serow (Capricornis milneedwardsii) and goral (Naemorhedus goral arnouxianus) compared with other mites from different hosts and geographic locations using ITS2 and cox1 sequences. 62
36201043 2022
8
Reproductive Losses and Their Causes in Alpacas-A Survey-Based Study. 62
36359154 2022
9
An updated and comprehensive review on the ethnomedicinal uses, phytochemistry, pharmacological activity and toxicological profile of Tinospora crispa (L.) Hook. f. & Thomson. 62
36345416 2022
10
Epidemic Scabies: New Treatment Challenges in an Ancient Disease. 62
36462668 2022
11
Erythrodermic scabies in an immunocompetent patient. 62
36262356 2022
12
The Data on Scabies Cases During COVID-19 Pandemic: A Two-Year Analysis From the Largest Portuguese Tertiary Teaching Hospital. 62
36368575 2022
13
Diagnosis and management of pediatric scabies: Results from a survey on 317 Italian dermatologists. 62
36116769 2022
14
Effects of ivermectin mass drug administration for malaria vector control on ectoparasites and soil-transmitted helminths: a cluster randomized trial. 62
36336245 2022
15
Health and illness in migrants and refugees arriving in Europe: analysis of the electronic Personal Health Record system. 62
35238944 2022
16
[Therapeutic peculiarities in diseases of the nipple skin]. 62
35925215 2022
17
Successful treatment of refractory crusted scabies. 62
36357115 2022
18
Lessons to learn from the analysis of routine health data from Moria Refugee Camp on Lesvos, Greece. 62
36415082 2022
19
Isoxazolines for treating canine demodicosis, sarcoptic mange (scabies), and lice infestation. 62
36325416 2022
20
Line-field confocal optical coherence tomography for the diagnosis of nodular scabies mimicking breast cancer skin metastasis. 62
36250785 2022
21
Comparison of sulfur ointment and permethrin treatments in scabies. 62
36193643 2022
22
A scabies outbreak in an inpatient rehabilitation setting. 62
36244573 2022
23
Clinical Conundrums: Differentiating Monkeypox From Similarly Presenting Infections. 62
36348880 2022
24
Increased Scabies Incidence at the Beginning of the 21st Century: What Do Reports from Europe and the World Show? 62
36295033 2022
25
Scabies revisited in the COVID-19 era. 62
35723910 2022
26
Comment on 'Unexpected consequences of SARS-CoV-2 pandemic: scabies infestation'. 62
35633116 2022
27
Effects of Sarcoptes scabiei Translationally Controlled Tumor Protein (TCTP) on Histamine Release and Degranulation of KU812 Cells. 62
36361656 2022
28
Structure-based in silico design and in vitro acaricidal activity assessment of Acacia nilotica and Psidium guajava extracts against Sarcoptes scabiei var. cuniculi. 62
35972548 2022
29
How secured and safe is the sanitation and hygiene services in a maximum-security correctional facility in Southwest Nigeria: a descriptive cross-sectional study. 62
34313160 2022
30
The Efficacy and Biopharmaceutical Properties of a Fixed-Dose Combination of Disulfiram and Benzyl Benzoate. 62
36142878 2022
31
Dermoscopy of nodular scabies: An observational study. 62
36149630 2022
32
Scabies incidence and association with skin and soft tissue infection in Loyalty Islands Province, New Caledonia: A 15-year retrospective observational study using electronic health records. 62
36067187 2022
33
European scabies challenge: what about permethrin-resistant mites? 62
35470925 2022
34
Mazzotti reaction: Ivermectin-associated polyarthritis after delayed scabies treatment. Case report and review of the literature. 62
34732299 2022
35
Decreases in scabies and lice cases among the pediatric and adult populations during COVID-19. 62
35860857 2022
36
Prescriptions for scabies are rapidly increasing in Spain: An ecological study with national prescription data, 2008-2021. 62
36151936 2022
37
Bullous Pemphigoid and Scabies: Is There an Association? 62
36074509 2022
38
Comparison of topical benzyl benzoate vs. oral ivermectin in treating scabies: A randomized study. 62
36097258 2022
39
Norwegian Scabies in an Atopic Patient Under Dupilumab Treatment. 62
35943363 2022
40
Spectrum of skin diseases in Maroon villages of the Maroni area, French Guiana. 62
35767188 2022
41
Patient Care and Treatment Strategies for Skin Diseases in Sub Saharan Africa: Role of Traditional and Western Medicines. 62
36121085 2022
42
Mass Drug Administration for the Control of Scabies: A Systematic Review and Meta-analysis. 62
35088849 2022
43
Comparative genomics of Sarcoptes scabiei provide new insights into adaptation to permanent parasitism and within-host species divergence. 62
36134513 2022
44
Prevalence and burden of skin diseases among the elderly in Singapore: a 15-year clinical cohort study. 62
35535625 2022
45
Disseminated scabies in a 2-month-old infant. 62
36110337 2022
46
Spinosad topical suspension (0.9%): a new topical treatment for scabies. 62
35799317 2022
47
Can we increase the success of scabies treatment? The effect of removing tunnels from patients in the success of scabies treatment. 62
35808934 2022
48
Drug eruption-like scabies surrepticius: an uncommonly described variant of scabies appearing in a non-classic clinical presentation. 62
36259867 2022
49
The national burden of scabies in Germany: a population-based approach using Internet search engine data. 62
35133608 2022
50
High prevalence of scabies in Auckland pre-schools. 62
35999795 2022

Variations for Scabies

Expression for Scabies

Search GEO for disease gene expression data for Scabies.

Pathways for Scabies

Pathways related to Scabies according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.75 CCR6 CD4 CD8A CFP COL17A1 IL13
2
Show member pathways
13.11 TNFRSF8 IL5 IL4 IL13 CD4 CCR6
3
Show member pathways
11.96 IL5 IL4 CD8A CD4
4
Show member pathways
11.78 IL4 CD8A CD4
5 11.77 IL5 IL4 CD8A CD4
6 11.68 IL5 IL4 IL13
7 11.59 IL5 IL4 IL13
8 11.49 IL5 IL4 IL13
9
Show member pathways
11.44 IL5 IL4 IL13
10 11.11 IL5 IL4 IL13
11 11.02 IL5 IL4 IL31 IL13 CD4
12 11 IL5 IL4 IL13 CD8A CD4 CCR6
13 10.98 IL5 IL4 IL13
14 10.92 IL5 IL4 IL13 CD4
15 10.91 IL5 IL4 IL13
16 10.72 IL4 CD4
17 10.51 IL5 IL4 IL13

GO Terms for Scabies

Cellular components related to Scabies according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.4 MBL2 IL13 CD8A CD4 CD1E CCR6
2 hemidesmosome GO:0030056 9.26 DST COL17A1

Biological processes related to Scabies according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell activation GO:0042110 9.85 IL4 CD8A CD4
2 positive regulation of B cell proliferation GO:0030890 9.73 IL5 IL4 IL13
3 immune system process GO:0002376 9.7 CD1E CD4 CD8A CFP IL31 MBL2
4 hemidesmosome assembly GO:0031581 9.62 DST COL17A1
5 immune response GO:0006955 9.53 IL5 IL4 IL13 CFP CD8A CD4
6 negative regulation of complement-dependent cytotoxicity GO:1903660 9.26 IL4 IL13

Molecular functions related to Scabies according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor binding GO:0005126 8.92 IL4 IL31 IL13

Sources for Scabies

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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