MCID: SCD003
MIFTS: 23

Scedosporiosis

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Scedosporiosis

MalaCards integrated aliases for Scedosporiosis:

Name: Scedosporiosis 58

Characteristics:

Orphanet epidemiological data:

58
scedosporiosis
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 58  
Rare infectious diseases


Summaries for Scedosporiosis

MalaCards based summary : Scedosporiosis is related to aspergillosis and cystic fibrosis. An important gene associated with Scedosporiosis is CSF3 (Colony Stimulating Factor 3). Affiliated tissues include brain, and related phenotypes are fever and immunodeficiency

Wikipedia : 73 Scedosporiosis is an infection caused by fungi from the genus Scedosporium which includes two... more...

Related Diseases for Scedosporiosis

Diseases related to Scedosporiosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 26)
# Related Disease Score Top Affiliating Genes
1 aspergillosis 10.2
2 cystic fibrosis 10.1
3 fusariosis 10.1
4 respiratory failure 10.0
5 toxic shock syndrome 10.0
6 fibrosis of extraocular muscles, congenital, 1 9.8
7 immune deficiency disease 9.8
8 leukemia, acute myeloid 9.8
9 exanthem 9.8
10 osteomyelitis 9.8
11 neutropenia 9.8
12 acute leukemia 9.8
13 eumycotic mycetoma 9.8
14 candidiasis 9.8
15 pneumothorax 9.8
16 chronic granulomatous disease 9.8
17 endophthalmitis 9.8
18 pulmonary coin lesion 9.8
19 pneumonia 9.8
20 acquired immunodeficiency syndrome 9.8
21 mucormycosis 9.8
22 myeloid leukemia 9.8
23 bronchiectasis 9.8
24 48,xyyy 9.8
25 mycetoma 9.8
26 argyria 9.8

Graphical network of the top 20 diseases related to Scedosporiosis:



Diseases related to Scedosporiosis

Symptoms & Phenotypes for Scedosporiosis

Human phenotypes related to Scedosporiosis:

58 31 (show all 35)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 fever 58 31 hallmark (90%) Very frequent (99-80%) HP:0001945
2 immunodeficiency 58 31 hallmark (90%) Very frequent (99-80%) HP:0002721
3 severe infection 58 31 hallmark (90%) Very frequent (99-80%) HP:0032169
4 opportunistic fungal infection 58 31 hallmark (90%) Very frequent (99-80%) HP:0032255
5 subcutaneous nodule 58 31 frequent (33%) Frequent (79-30%) HP:0001482
6 pneumonia 58 31 frequent (33%) Frequent (79-30%) HP:0002090
7 ectopic calcification 58 31 frequent (33%) Frequent (79-30%) HP:0010766
8 unusual skin infection 58 31 frequent (33%) Frequent (79-30%) HP:0032162
9 pulmonary tuberculosis 58 31 frequent (33%) Frequent (79-30%) HP:0032262
10 diabetes mellitus 58 31 occasional (7.5%) Occasional (29-5%) HP:0000819
11 sinusitis 58 31 occasional (7.5%) Occasional (29-5%) HP:0000246
12 pulmonary fibrosis 58 31 occasional (7.5%) Occasional (29-5%) HP:0002206
13 arthralgia/arthritis 58 31 occasional (7.5%) Occasional (29-5%) HP:0005059
14 hemoptysis 58 31 occasional (7.5%) Occasional (29-5%) HP:0002105
15 cough 58 31 occasional (7.5%) Occasional (29-5%) HP:0012735
16 pericarditis 58 31 occasional (7.5%) Occasional (29-5%) HP:0001701
17 endocarditis 58 31 occasional (7.5%) Occasional (29-5%) HP:0100584
18 osteomyelitis 58 31 occasional (7.5%) Occasional (29-5%) HP:0002754
19 sepsis 58 31 occasional (7.5%) Occasional (29-5%) HP:0100806
20 respiratory failure 58 31 occasional (7.5%) Occasional (29-5%) HP:0002878
21 brain imaging abnormality 58 31 occasional (7.5%) Occasional (29-5%) HP:0410263
22 abnormal renal morphology 58 31 occasional (7.5%) Occasional (29-5%) HP:0012210
23 pleuritis 58 31 occasional (7.5%) Occasional (29-5%) HP:0002102
24 septic arthritis 58 31 occasional (7.5%) Occasional (29-5%) HP:0003095
25 bronchitis 58 31 occasional (7.5%) Occasional (29-5%) HP:0012387
26 abnormal thrombosis 58 31 occasional (7.5%) Occasional (29-5%) HP:0001977
27 decreased pulmonary function 58 31 occasional (7.5%) Occasional (29-5%) HP:0005952
28 bronchial breath sound 58 31 occasional (7.5%) Occasional (29-5%) HP:0031994
29 pleural empyema 58 31 occasional (7.5%) Occasional (29-5%) HP:0011919
30 invasive fungal infection 58 31 occasional (7.5%) Occasional (29-5%) HP:0020101
31 fungal meningitis 58 31 occasional (7.5%) Occasional (29-5%) HP:0032159
32 apical pulmonary opacity 58 31 occasional (7.5%) Occasional (29-5%) HP:0032176
33 abnormal jejunum morphology 31 occasional (7.5%) HP:0005265
34 unusual cns infection 58 Occasional (29-5%)
35 abnormality of the jejunum 58 Occasional (29-5%)

Drugs & Therapeutics for Scedosporiosis

Search Clinical Trials , NIH Clinical Center for Scedosporiosis

Genetic Tests for Scedosporiosis

Anatomical Context for Scedosporiosis

MalaCards organs/tissues related to Scedosporiosis:

40
Brain

Publications for Scedosporiosis

Articles related to Scedosporiosis:

(show top 50) (show all 107)
# Title Authors PMID Year
1
Scedosporium and Lomentospora Infections: Contemporary Microbiological Tools for the Diagnosis of Invasive Disease. 61
33406673 2021
2
Isolation of fungal communities and identification of Scedosporium species complex with pathogenic potentials from a pigsty in Phra Nakhon Si Ayutthaya, Thailand. 61
33582822 2021
3
Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScopeⓇ-Global Registry for Emerging Fungal Infections. 61
32798532 2020
4
Scedosporiosis/lomentosporiosis observational study (SOS): Clinical significance of Scedosporium species identification. 61
33037432 2020
5
Disseminated Scedosporium apiospermum infection in a Maremmano-Abruzzese sheepdog. 61
33008393 2020
6
Invasive Scedosporium and Lomentosora infections in the era of antifungal prophylaxis: A 20-year experience from a single centre in Spain. 61
32749009 2020
7
Scedosporium Apiospermum: Rare Cause of Brain Abscess in an Immunocompetent Patient. 61
32859840 2020
8
Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. 61
31818813 2020
9
Detection of the 'Big Five' mold killers of humans: Aspergillus, Fusarium, Lomentospora, Scedosporium and Mucormycetes. 61
32386603 2020
10
Synthesis of the Hydroxamate Siderophore Nα-Methylcoprogen B in Scedosporium apiospermum Is Mediated by sidD Ortholog and Is Required for Virulence. 61
33194829 2020
11
Pulmonary scedosporiosis in a patient with acute hematopoietic failure: Diagnosis aided by next-generation sequencing. 61
31170547 2019
12
Subcutaneous Scedosporiosis with Dissemination. 61
31516142 2019
13
Transcriptional profiling of Scedosporium apiospermum enzymatic antioxidant gene battery unravels the involvement of thioredoxin reductases against chemical and phagocytic cells oxidative stress. 61
29889264 2019
14
Combined antifungal therapy is superior to monotherapy in pulmonary scedosporiosis in cystic fibrosis. 61
30297214 2019
15
Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope®. 61
30628529 2019
16
Experimental Scedosporiosis Induces Cerebral Oedema Associated with Abscess regarding Aquaporin-4 and Nrf-2 Depletions. 61
31080825 2019
17
[Epidemiology of invasive mycoses: A landscape in continuous change]. 61
30466999 2018
18
Identification of 14-α-Lanosterol Demethylase (CYP51) in Scedosporium Species. 61
29891611 2018
19
Pseudallescheria/Scedosporium complex species: From saprobic to pathogenic fungus. 61
29567285 2018
20
Recent Advances in the Treatment of Scedosporiosis and Fusariosis. 61
29912161 2018
21
Pharmacodynamics of Voriconazole for Invasive Pulmonary Scedosporiosis. 61
29439967 2018
22
Impact of Infection Status and Cyclosporine on Voriconazole Pharmacokinetics in an Experimental Model of Cerebral Scedosporiosis. 61
29491040 2018
23
Scedosporium apiospermum infection of the urinary system with a review of treatment options and cases in the literature. 61
29111602 2018
24
A cluster of scedosporiosis in lung transplant candidates and recipients: The Zurich experience and review of the literature. 61
29044831 2018
25
Spontaneous Remission of Subcutaneous Scedosporiosis Caused by Scedosporium dehoogii in a Psoriatic Patient. 61
28074414 2017
26
Voriconazole MICs are predictive for the outcome of experimental disseminated scedosporiosis. 61
28031271 2017
27
Scedosporiosis presenting with subcutaneous nodules in an immunocompromised patient. 61
27853000 2017
28
Rare fungal infectious agents: a lurking enemy. 61
29152230 2017
29
Discrimination of Aspergillosis, Mucormycosis, Fusariosis, and Scedosporiosis in Formalin-Fixed Paraffin-Embedded Tissue Specimens by Use of Multiple Real-Time Quantitative PCR Assays. 61
27605714 2016
30
Peptidorhamnomannan negatively modulates the immune response in a scedosporiosis murine model. 61
27343286 2016
31
Pulmonary scedosporiosis mimicking aspergilloma in an immunocompetent host: a case report and review of the literature. 61
26353885 2016
32
Scedosporiosis in a Combined Kidney and Liver Transplant Recipient: A Case Report of Possible Transmission from a Near-Drowning Donor. 61
28070441 2016
33
Cluster analysis of Scedosporium boydii infections in a single hospital. 61
26330287 2015
34
Posaconazole liquid suspension in solid organ transplant recipients previously treated with voriconazole. 61
25846433 2015
35
Fatal scedosporiosis in multiple solid organ allografts transmitted from a nearly-drowned donor. 61
25639881 2015
36
Assessing micafungin/triazole combinations for the treatment of invasive scedosporiosis due to Scedosporium apiospermum and Scedosporium boydii. 61
24986494 2014
37
Disseminated Scedosporium prolificans infection in a Labrador retriever with immune mediated haemolytic anaemia. 61
25473599 2014
38
Epidemiology, clinical manifestations, and outcomes of Scedosporium infections among solid organ transplant recipients. 61
24962102 2014
39
[Fungal infections of the central nervous system in the immunocompetent host]. 61
24154754 2013
40
Epidemiology of invasive fungal infections in the intensive care unit: results of a multicenter Italian survey (AURORA Project). 61
23463186 2013
41
Treatment of a brain abscess caused by Scedosporium apiospermum and Phaeoacremonium parasiticum in a renal transplant recipient. 61
24050081 2013
42
Successful prevention of scedosporiosis after lung transplantation in a cystic fibrosis patient by combined local and systemic triazole therapy. 61
24432232 2013
43
Experimental models of disseminated scedosporiosis with cerebral involvement. 61
23426955 2013
44
Locally extensive angio-invasive Scedosporium prolificans infection following resection for squamous cell lung carcinoma. 61
24432228 2013
45
[Clinical and radiological aspects of mucormycosis]. 61
23510521 2013
46
Scedosporium apiospermum eumycetoma successfully treated with oral voriconazole: report of a case and review of the Brazilian reports on scedosporiosis. 61
23563766 2013
47
Two cases of severe pneumonia after the 2011 Great East Japan Earthquake. 61
23908944 2012
48
Hospital costs, length of stay and mortality attributable to invasive scedosporiosis in haematology patients. 61
22643193 2012
49
[Fungemia caused by Scedosporium prolificans in myelodysplastic syndrome]. 61
22416481 2012
50
Opportunistic fungal infections in the Asia-Pacific region. 61
21905945 2012

Variations for Scedosporiosis

Expression for Scedosporiosis

Search GEO for disease gene expression data for Scedosporiosis.

Pathways for Scedosporiosis

GO Terms for Scedosporiosis

Sources for Scedosporiosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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