MCID: SCH004
MIFTS: 27

Schizoid Personality Disorder

Categories: Mental diseases

Aliases & Classifications for Schizoid Personality Disorder

MalaCards integrated aliases for Schizoid Personality Disorder:

Name: Schizoid Personality Disorder 12 73 44 15 70 32

Classifications:



External Ids:

Disease Ontology 12 DOID:10936
ICD9CM 34 301.2
MeSH 44 D012557
NCIt 50 C92631
SNOMED-CT 67 192486009
ICD10 32 F60.1
UMLS 70 C0036339

Summaries for Schizoid Personality Disorder

Disease Ontology : 12 A personality disorder that is characterized by a lack of interest in social relationships, a tendency towards a solitary lifestyle, secretiveness, emotional coldness and sometimes sexual apathy, with a simultaneous rich, elaborate and exclusively internal fantasy world.

MalaCards based summary : Schizoid Personality Disorder is related to schizotypal personality disorder and autism spectrum disorder. An important gene associated with Schizoid Personality Disorder is PRODH (Proline Dehydrogenase 1).

Wikipedia : 73 Schizoid personality disorder (/ˈskɪtsɔɪd, ˈskɪdzɔɪd/, often abbreviated as SPD or SzPD) is a... more...

Related Diseases for Schizoid Personality Disorder

Diseases related to Schizoid Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 schizotypal personality disorder 30.3 ZNF804A PRODH DISC1
2 autism spectrum disorder 29.4 ZNF804A PRODH FMR1 DRD2 DISC1
3 personality disorder 10.7
4 avoidant personality disorder 10.5
5 voyeurism 10.2 PRODH AVEN
6 tic disorder 10.2 PRODH DRD2
7 schizophrenia 9 10.2 PRODH DISC1
8 paranoid personality disorder 10.2 DISC1 CPZ
9 bestiality 10.2 DRD2 CPZ
10 schizophrenia 2 10.2 PRODH DISC1
11 cannabis abuse 10.2 PRODH DRD2
12 cyclothymic disorder 10.2 DRD2 DISC1
13 echolalia 10.1 PRODH FMR1
14 phobia, specific 10.1 PRODH FMR1
15 alexithymia 10.1
16 schizophrenia 1 10.1 PRODH DISC1
17 delusional disorder 10.0 PRODH DRD2 DISC1
18 mental depression 10.0 PRODH DRD2 DISC1
19 schizoaffective disorder 10.0 PRODH DRD2 DISC1
20 phobic disorder 10.0 PRODH FMR1 DRD2
21 social phobia 10.0 PRODH FMR1 DRD2
22 speech disorder 10.0 PRODH FMR1 DRD2
23 movement disease 10.0 PRODH FMR1 DRD2
24 mood disorder 10.0 PRODH DRD2 DISC1
25 functioning pituitary adenoma 9.9 GHR DRD2
26 bipolar i disorder 9.9 ZNF804A DRD2
27 fragile x syndrome 9.9 PRODH FMR1 DISC1
28 sotos syndrome 1 9.8 PRODH FMR1
29 digeorge syndrome 9.8 PRODH FMR1 DISC1
30 specific developmental disorder 9.8 PRODH FMR1 DRD2 DISC1
31 pervasive developmental disorder 9.8 PRODH FMR1 DRD2 DISC1
32 anxiety 9.8 PRODH FMR1 DRD2 DISC1
33 schizophreniform disorder 9.8 ZNF804A PRODH DRD2 DISC1
34 psychotic disorder 9.8 ZNF804A PRODH DRD2 DISC1
35 velocardiofacial syndrome 9.7 ZNF804A PRODH FMR1 DISC1
36 attention deficit-hyperactivity disorder 9.7 ZNF804A PRODH FMR1 DRD2
37 bipolar disorder 9.7 ZNF804A PRODH DRD2 DISC1
38 prader-willi syndrome 9.6 PRODH GHR FMR1
39 schizophrenia 9.5 ZNF804A PRODH FMR1 DRD2 DISC1
40 autism 9.5 ZNF804A PRODH FMR1 DRD2 DISC1
41 disease of mental health 9.2 ZNF804A PRODH FMR1 DRD2 DISC1 CPZ

Comorbidity relations with Schizoid Personality Disorder via Phenotypic Disease Network (PDN):


Acute Cystitis Major Depressive Disorder
Schizophreniform Disorder

Graphical network of the top 20 diseases related to Schizoid Personality Disorder:



Diseases related to Schizoid Personality Disorder

Symptoms & Phenotypes for Schizoid Personality Disorder

Drugs & Therapeutics for Schizoid Personality Disorder

Search Clinical Trials , NIH Clinical Center for Schizoid Personality Disorder

Cochrane evidence based reviews: schizoid personality disorder

Genetic Tests for Schizoid Personality Disorder

Anatomical Context for Schizoid Personality Disorder

Publications for Schizoid Personality Disorder

Articles related to Schizoid Personality Disorder:

(show top 50) (show all 90)
# Title Authors PMID Year
1
Commentary about social avoidance and its significance in adolescents and young adults. 61
33465524 2021
2
Measuring Behavioral Inhibition and Behavioral Activation in Older Adults: Construct Validity of the Dutch BIS/BAS Scales. 61
33736472 2021
3
The Co-Occurrence of Trauma Related Disorder and Borderline Personality Disorder: AQ Study on a Clinical Sample of Patients Seeking Psychotherapy Treatment. 61
33349435 2021
4
On the Continuity Between Autistic and Schizoid Personality Disorder Trait Burden: A Prospective Study in Adolescence. 61
31856140 2020
5
Homicidal Ideation and Forensic Psychopathology: Evidence From the 2016 Nationwide Emergency Department Sample (NEDS). 61
31404481 2020
6
Theory of Mind (ToM) Performance in High Functioning Autism (HFA) and Schizotypal-Schizoid Personality Disorders (SSPD) Patients. 61
31104261 2019
7
Beyond the mental pain: A case-control study on the contribution of schizoid personality disorder symptoms to medically serious suicide attempts. 61
30852349 2019
8
Disparities in the management of cardiovascular risk factors in patients with psychiatric disorders: a systematic review and meta-analysis. 61
29490716 2018
9
Avoidant personality disorder: current insights. 61
29563846 2018
10
[The concept of schizoidia in psychiatry : From schizoidia to schizotypy and cluster A personality disorders]. 61
28699102 2017
11
Mating Strategies and Sexual Functioning in Personality Disorders: A Comprehensive Review of Literature. 61
28526631 2017
12
[Schizotypy: detachment or magical fusion]. 61
28424380 2017
13
A Case Study of Paternal Filicide-Suicide: Personality Disorder, Motives, and Victim Choice. 61
27537187 2017
14
[Aripiprazole, gambling disorder and compulsive sexuality]. 61
26923999 2016
15
Review of pharmacologic treatment in cluster A personality disorders. 61
29955451 2016
16
Personality and psychotic symptoms as predictors of self-harm and attempted suicide. 61
26417781 2015
17
Psychosis. 61
26039850 2015
18
Poor Validity of the DSM-IV Schizoid Personality Disorder Construct as a Diagnostic Category. 61
25248009 2015
19
Effects of Aesthetic Chills on a Cardiac Signature of Emotionality. 61
26083383 2015
20
Patient personality and therapist response: an empirical investigation. 61
24077643 2014
21
Factor Analysis Demonstrates a Common Schizoidal Phenotype within Autistic and Schizotypal Tendency: Implications for Neuroscientific Studies. 61
25221527 2014
22
The association between probable personality disorders and smoking cessation and maintenance. 61
23628430 2013
23
Are alexithymia and schizoid personality disorder synonymous diagnoses? 61
23021894 2013
24
[Neuropsychological syndromes of non-psychotic mental disorders of youthful age]. 61
24430030 2013
25
Schizoid personality disorder. 61
23281676 2012
26
[The projection of autism spectrum disorders in adult life]. 61
22796975 2012
27
Focal parietal necrosis of the sigmoid due to atypical neuroleptics: a case report. 61
22870793 2012
28
Failures of the 'moral defence' in the films Shutter Island, Inception and Memento: narcissism or schizoid personality disorder? 61
22320143 2012
29
[Treatment of schizoid personality disorder: Reflections of a cinephile]. 61
23254831 2012
30
Gender differences in firesetting: results from the national epidemiologic survey on alcohol and related conditions (NESARC). 61
21684614 2011
31
Sociodemographic and diagnostic characteristics of homicidal and nonhomicidal sexual offenders. 61
21981447 2011
32
[A case of successful psychotherapy of schizoid personality disorder with hypochondria using the method of creative self-expression]. 61
21898950 2011
33
A source, a cascade, a schizoid: a heuristic proposal from the Longitudinal Study of Personality Disorders. 61
20883587 2010
34
Gender-related influences of parental alcoholism on the prevalence of psychiatric illnesses: analysis of the National Epidemiologic Survey on Alcohol and Related Conditions. 61
20645936 2010
35
[Gottfried Benn and schizoidism]. 61
19768445 2010
36
Asexuality: a mixed-methods approach. 61
19082703 2010
37
Developmental instability in social anhedonia: an examination of minor physical anomalies and clinical characteristics. 61
19944570 2010
38
"I am not complaining"--ambivalence construct in schizoid personality disorder. 61
19711768 2009
39
Does change in temperament predict change in schizoid personality disorder? A methodological framework and illustration from the Longitudinal Study of Personality Disorders. 61
19825265 2009
40
[Autism: exploring historical psychiatric and psychological concepts]. 61
18677680 2008
41
Personality disorder features as predictors of symptoms five years post-treatment. 61
18463992 2008
42
Assessing interpersonal aspects of schizoid personality disorder: preliminary validation studies. 61
18444113 2008
43
[The capacity for mentalization in depressive patients: a pilot study]. 61
19049686 2008
44
Selective mutism and social anxiety disorder: all in the family? 61
18049296 2007
45
The heritability of cluster A personality disorders assessed by both personal interview and questionnaire. 61
17224098 2007
46
The role of personality disorder in 'difficult to reach' patients with depression: findings from the ODIN study. 61
17127039 2007
47
Gender bias in diagnostic criteria for personality disorders: an item response theory analysis. 61
17324027 2007
48
[Peculiarities of social adaptation in adolescents with schizoid personality disorder: a follow-up study]. 61
18379484 2007
49
Is schizoid personality a forerunner of homicidal or suicidal behavior?: a case study. 61
16648387 2006
50
Personality disorders and romantic adult attachment: a comparison of secure and insecure attached child molesters. 61
16510885 2006

Variations for Schizoid Personality Disorder

Expression for Schizoid Personality Disorder

Search GEO for disease gene expression data for Schizoid Personality Disorder.

Pathways for Schizoid Personality Disorder

GO Terms for Schizoid Personality Disorder

Cellular components related to Schizoid Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 synapse GO:0045202 9.62 FMR1 FBXL20 DRD2 DISC1
2 postsynaptic density GO:0014069 9.43 FMR1 DRD2 DISC1
3 axon terminus GO:0043679 9.37 FMR1 DRD2
4 presynapse GO:0098793 9.33 ZNF804A FMR1 FBXL20
5 dendritic spine GO:0043197 9.13 ZNF804A FMR1 DRD2
6 axon GO:0030424 8.92 ZNF804A FMR1 DRD2 DISC1

Biological processes related to Schizoid Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Wnt signaling pathway GO:0016055 9.58 DRD2 DISC1 CPZ
2 regulation of synaptic vesicle exocytosis GO:2000300 9.46 FBXL20 DRD2
3 regulation of neuron projection development GO:0010975 9.43 ZNF804A DISC1
4 positive regulation of multicellular organism growth GO:0040018 9.37 GHR DRD2
5 response to morphine GO:0043278 9.32 GHR DRD2
6 positive regulation of receptor internalization GO:0002092 9.26 FMR1 DRD2
7 positive regulation of neuroblast proliferation GO:0002052 9.16 DRD2 DISC1
8 negative regulation of voltage-gated calcium channel activity GO:1901386 8.96 FMR1 DRD2
9 regulation of dendritic spine development GO:0060998 8.62 FMR1 DISC1

Sources for Schizoid Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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