SCZD10
MCID: SCH064
MIFTS: 27

Schizophrenia 10 (SCZD10)

Categories: Ear diseases, Genetic diseases, Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Schizophrenia 10

MalaCards integrated aliases for Schizophrenia 10:

Name: Schizophrenia 10 57 12 13 15 70
Sczd10 57 12
Schizophrenia Susceptibility Locus, Chromosome 15q15-Related 57
Catatonia, Periodic 57

Characteristics:

OMIM®:

57 (Updated 20-May-2021)
Inheritance:
autosomal dominant


HPO:

31
schizophrenia 10:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:0070086
OMIM® 57 605419
MedGen 41 C0543918
UMLS 70 C0543918

Summaries for Schizophrenia 10

Disease Ontology : 12 A schizophrenia that has material basis in an autosomal dominant mutation of SCZD10 on chromosome 15q15.

MalaCards based summary : Schizophrenia 10, also known as sczd10, is related to schizophrenia and autosomal dominant nocturnal frontal lobe epilepsy, and has symptoms including grimacing An important gene associated with Schizophrenia 10 is SCZD10 (Schizophrenia Disorder 10 (Periodic Catatonia)). Affiliated tissues include cortex, prefrontal cortex and eye, and related phenotypes are hallucinations and mask-like facies

More information from OMIM: 605419

Related Diseases for Schizophrenia 10

Graphical network of the top 20 diseases related to Schizophrenia 10:



Diseases related to Schizophrenia 10

Symptoms & Phenotypes for Schizophrenia 10

Human phenotypes related to Schizophrenia 10:

31 (show all 6)
# Description HPO Frequency HPO Source Accession
1 hallucinations 31 HP:0000738
2 mask-like facies 31 HP:0000298
3 schizophrenia 31 HP:0100753
4 psychotic episodes 31 HP:0000725
5 delusions 31 HP:0000746
6 disturbance of facial expression 31 HP:0005324

Symptoms via clinical synopsis from OMIM®:

57 (Updated 20-May-2021)
Neurologic Behavioral Psychiatric Manifestations:
hallucinations
psychotic episodes
delusions
schizophrenia, atypical
stuporous catatonia
more
Head And Neck Face:
grimacing
masklike facies
derangements of facial expression

Clinical features from OMIM®:

605419 (Updated 20-May-2021)

UMLS symptoms related to Schizophrenia 10:


grimacing

Drugs & Therapeutics for Schizophrenia 10

Search Clinical Trials , NIH Clinical Center for Schizophrenia 10

Genetic Tests for Schizophrenia 10

Anatomical Context for Schizophrenia 10

MalaCards organs/tissues related to Schizophrenia 10:

40
Cortex, Prefrontal Cortex, Eye, Cingulate Cortex, Brain

Publications for Schizophrenia 10

Articles related to Schizophrenia 10:

(show top 50) (show all 64)
# Title Authors PMID Year
1
De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia. 57
23042115 2012
2
Periodic catatonia: confirmation of linkage to chromosome 15 and further evidence for genetic heterogeneity. 57
12384773 2002
3
Splitting schizophrenia: periodic catatonia-susceptibility locus on chromosome 15q15. 57
11001582 2000
4
Genetic heterogeneity in catatonic schizophrenia: a family study. 57
8725746 1996
5
Periodic catatonia: a schizophrenic subtype with major gene effect and anticipation. 57
7669819 1995
6
Postmortem Studies of Neuroinflammation in Autism Spectrum Disorder: a Systematic Review. 61
32529489 2020
7
Frontal activity measured by near-infrared spectroscopy in patients taking different atypical antipsychotic drugs: A cross-sectional study. 61
29329742 2018
8
Health care use, drug treatment and comorbidity in patients with schizophrenia or non-affective psychosis in Sweden: a cross-sectional study. 61
29284436 2017
9
A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression. 61
26903267 2016
10
What are the top 10 physical activity research questions in schizophrenia? 61
26728764 2016
11
Changes in verbal learning and memory in schizophrenia and non-psychotic controls in midlife: A nine-year follow-up in the Northern Finland Birth Cohort study 1966. 61
26168931 2015
12
A pilot study: comparative research of social functioning, circadian rhythm parameters, and cognitive function among institutional inpatients, and outpatients with chronic schizophrenia and healthy elderly people. 61
25092490 2015
13
Impaired top-down modulation of saccadic latencies in patients with schizophrenia but not in first-degree relatives. 61
25759644 2015
14
Cerebellar motor learning deficits in medicated and medication-free men with recent-onset schizophrenia. 61
24083457 2014
15
Pharmacological approaches to the management of schizophrenia: 10 years on. 61
23616381 2013
16
Onset Pattern and Long-Term Prognosis in Schizophrenia: 10-Year Longitudinal Follow-Up Study. 61
23840649 2013
17
Testing the genomic enrichment of a large copy number variation within schizophrenia linkage regions. 61
22914616 2012
18
Microvascular changes in late-life schizophrenia and mood disorders: stereological assessment of capillary diameters in anterior cingulate cortex. 61
22360590 2012
19
The chromosome 15q14 locus for bipolar disorder and schizophrenia: is C15orf53 a major candidate gene? 61
22944046 2012
20
Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia. 61
22349577 2012
21
Predictors of death from natural causes in schizophrenia: 10-year follow-up of a community cohort. 61
21559973 2012
22
Comparison of facial expression in patients with obsessive-compulsive disorder and schizophrenia using the Facial Action Coding System: a preliminary study. 61
23269872 2012
23
Serum levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with different psychiatric disorders. 61
20937362 2011
24
Cannabis use and the course of schizophrenia: 10-year follow-up after first hospitalization. 61
20478874 2010
25
Functional connectivity and brain networks in schizophrenia. 61
20631176 2010
26
Increased inferior frontal activation during word generation: a marker of genetic risk for schizophrenia but not bipolar disorder? 61
19479729 2009
27
White matter alterations in deficit schizophrenia. 61
19052539 2009
28
Schizotypal traits impact upon executive working memory and aspects of IQ. 61
18423612 2008
29
Inhibitory control and spatial working memory: a saccadic eye movement study of negative symptoms in schizophrenia. 61
17897722 2008
30
Relationship between financial competence and cognitive function in patients with schizophrenia. 61
17875022 2007
31
Serotonergic response to stress: a protective factor against abnormal dopaminergic reactivity in schizophrenia? 61
17419010 2007
32
Immunohistochemical and immunoblot analysis of Dopamine and cyclic AMP-regulated phosphoprotein, relative molecular mass 32,000 (DARPP-32) in the prefrontal cortex of subjects with schizophrenia and bipolar disorder. 61
17521792 2007
33
The child and adolescent first-episode psychosis study (CAFEPS): design and baseline results. 61
17267179 2007
34
Self-face recognition and theory of mind in patients with schizophrenia and first-degree relatives. 61
16979876 2006
35
EEG correlates of startle reflex with reactivity to eye opening in psychiatric disorders: preliminary results. 61
16929710 2006
36
Elevated plasma levels of lipoprotein(a) in psychiatric patients: a possible contribution to increased vascular risk. 61
16516110 2006
37
[Quality of sleep in hospitalized psychiatric patients]. 61
16562640 2006
38
Brain MRI abnormalities in schizophrenia: same genes or same environment? 61
16164764 2005
39
Auditory P300 in high-risk, recent-onset and chronic schizophrenia. 61
15944141 2005
40
Functional consequences of PRODH missense mutations. 61
15662599 2005
41
Perspective-taking deficits in people with schizophrenia spectrum disorders: a prospective investigation. 61
15724888 2004
42
Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines. 61
15465982 2004
43
[Suicidal poisoning with antihypertensive drugs]. 61
14569890 2003
44
Medication compliance and comorbid substance abuse in schizophrenia: impact on community survival 4 years after a relapse. 61
11950550 2002
45
A schizophrenia-susceptibility locus at 6q25, in one of the world's largest reported pedigrees. 61
11389481 2001
46
Access to services at assisted reproductive technology clinics: a survey of policies and practices. 61
11262458 2001
47
Fluvoxamine reduces the clozapine dosage needed in refractory schizophrenic patients. 61
10982203 2000
48
Functional anatomy of verbal fluency in people with schizophrenia and those at genetic risk. Focal dysfunction and distributed disconnectivity reappraised. 61
10789327 2000
49
[Neuroleptics in the newspaper. A mass media analysis]. 61
10457969 1999
50
The size and fibre composition of the corpus callosum with respect to gender and schizophrenia: a post-mortem study. 61
10050898 1999

Variations for Schizophrenia 10

Expression for Schizophrenia 10

Search GEO for disease gene expression data for Schizophrenia 10.

Pathways for Schizophrenia 10

GO Terms for Schizophrenia 10

Sources for Schizophrenia 10

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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