MCID: SCH086
MIFTS: 21

Schizophrenia 11

Categories: Ear diseases, Genetic diseases, Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Schizophrenia 11

MalaCards integrated aliases for Schizophrenia 11:

Name: Schizophrenia 11 57 12 15 71
Schizophrenia Susceptibility Locus, Chromosome 10q-Related 57 13
Sczd11 57 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0070087
OMIM® 57 608078
MedGen 41 C1842605
UMLS 71 C1842605

Summaries for Schizophrenia 11

Disease Ontology : 12 A schizophrenia that has material basis in a mutation on chromosome 10q22.3.

MalaCards based summary : Schizophrenia 11, also known as schizophrenia susceptibility locus, chromosome 10q-related, is related to schizophrenia and schizophrenia 6. An important gene associated with Schizophrenia 11 is SCZD11 (Schizophrenia Susceptibility Locus, Chromosome 10q-Related). Affiliated tissues include brain, cortex and prefrontal cortex.

More information from OMIM: 608078

Related Diseases for Schizophrenia 11

Diseases in the Schizophrenia family:

Schizophrenia 1 Schizophrenia 3
Schizophrenia 4 Schizophrenia 6
Schizophrenia 5 Schizophrenia 7
Schizophrenia 8 Schizophrenia 2
Schizophrenia 9 Schizophrenia 10
Schizophrenia 11 Schizophrenia 12
Schizophrenia 14 Schizophrenia 13
Schizophrenia 15 Schizophrenia 16
Schizophrenia 18 Schizophrenia 19
Early-Onset Schizophrenia

Diseases related to Schizophrenia 11 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 schizophrenia 11.1
2 schizophrenia 6 9.1 TRDN MIR662 MIR657

Symptoms & Phenotypes for Schizophrenia 11

Clinical features from OMIM®:

608078 (Updated 05-Mar-2021)

Drugs & Therapeutics for Schizophrenia 11

Search Clinical Trials , NIH Clinical Center for Schizophrenia 11

Genetic Tests for Schizophrenia 11

Anatomical Context for Schizophrenia 11

MalaCards organs/tissues related to Schizophrenia 11:

40
Brain, Cortex, Prefrontal Cortex, Retina, Thalamus, Amygdala

Publications for Schizophrenia 11

Articles related to Schizophrenia 11:

(show all 35)
# Title Authors PMID Year
1
Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain. 57
20713722 2010
2
Fine mapping on chromosome 10q22-q23 implicates Neuregulin 3 in schizophrenia. 57
19118813 2009
3
Genomewide linkage scan for schizophrenia susceptibility loci among Ashkenazi Jewish families shows evidence of linkage on chromosome 10q22. 57
12929083 2003
4
Genetic association of the human GAP43 gene with schizophrenia in a Northeast Chinese Han population. 61
33165371 2020
5
Evaluation of Four-Year Stability of Unspecified Psychosis. 61
30911237 2019
6
Metabolic Abnormalities in the Hippocampus of Patients with Schizophrenia: A 3D Multivoxel MR Spectroscopic Imaging Study at 3T. 61
27444940 2016
7
Exome Sequencing of Familial Bipolar Disorder. 61
27120077 2016
8
Association between alcohol and substance use disorders and all-cause and cause-specific mortality in schizophrenia, bipolar disorder, and unipolar depression: a nationwide, prospective, register-based study. 61
26277044 2015
9
Day care as an innovative approach in psychiatry: Analysis of Lucknow experience. 61
26124522 2015
10
An fMRI study of visual lexical decision in patients with schizophrenia and clinical high-risk individuals. 61
24893907 2014
11
Investigating affective prosody in psychosis: a study using the Comprehensive Affective Testing System. 61
24012143 2013
12
The effects of industry sponsorship on comparator selection in trial registrations for neuropsychiatric conditions in children. 61
24376857 2013
13
N-Acetyl-Aspartate Level is Decreased in the Prefrontal Cortex in Subjects At-Risk for Schizophrenia. 61
24046751 2013
14
A window into the brain: an in vivo study of the retina in schizophrenia using optical coherence tomography. 61
22917503 2012
15
Lower ß2*-nicotinic acetylcholine receptor availability in smokers with schizophrenia. 61
22193533 2012
16
Habituation and prepulse inhibition of acoustic startle in rodents. 61
21912367 2011
17
Positive association of the human STON2 gene with schizophrenia. 61
21407139 2011
18
Inefficient neural activity in patients with schizophrenia and nonpsychotic relatives of schizophrenic patients: evidence from a working memory task. 61
19426993 2009
19
Amygdala volume and verbal memory performance in schizophrenia and bipolar disorder. 61
19372768 2009
20
Saccadic impairment in schizophrenia with prominent negative symptoms. 61
18766026 2008
21
Psychiatric illness and adverse pregnancy outcome. 61
18082746 2008
22
GABAA/Benzodiazepine receptor binding in patients with schizophrenia using [11C]Ro15-4513, a radioligand with relatively high affinity for alpha5 subunit. 61
18042347 2008
23
First episode psychosis: a novel methodology reveals higher than expected incidence; a reality-based population profile in Northumberland, UK. 61
15482417 2004
24
In vivo 31P NMR spectroscopy shows an increase in glycerophosphorylcholine concentration without alterations in mitochondrial function in the prefrontal cortex of medicated schizophrenic patients at rest. 61
15255985 2004
25
Effect of clozapine on serum leptin, insulin levels, and body weight and composition in patients with schizophrenia. 61
12921912 2003
26
[Meta-analysis of assisted music therapy for chronic schizophrenia]. 61
12905680 2002
27
Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation. 61
11926935 2002
28
Comparison of preferences for health outcomes in schizophrenia among stakeholder groups. 61
10867115 2000
29
Absence of neurodegeneration in the thalamus and caudate of elderly patients with schizophrenia. 61
10725527 2000
30
Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia. 61
9734544 1998
31
Ageing changes of morphological characteristics of cavum septi pellucidi in adults: a dissectional study. 61
9719776 1998
32
Studies of aggressive behaviour in schizophrenia: is there a response bias? 61
9383945 1997
33
An evaluation of community-based psychiatric care for people with treated long-term mental illness. 61
7551605 1995
34
Cost of schizophrenia in a randomized trial of home-based treatment. 61
1947865 1991
35
Additional studies on side effects of melperone in long-term therapy for 1 to 15 years in psychiatric patients. 61
6113835 1981

Variations for Schizophrenia 11

Expression for Schizophrenia 11

Search GEO for disease gene expression data for Schizophrenia 11.

Pathways for Schizophrenia 11

GO Terms for Schizophrenia 11

Sources for Schizophrenia 11

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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