MCID: SCH045
MIFTS: 23

Schizophrenia 12

Categories: Ear diseases, Genetic diseases, Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Schizophrenia 12

MalaCards integrated aliases for Schizophrenia 12:

Name: Schizophrenia 12 57 12 13 15 70
Sczd12 57 12
Schizophrenia Susceptibility Locus, Chromosome 1p-Related 57

Classifications:



External Ids:

Disease Ontology 12 DOID:0070088
OMIM® 57 608543
MedGen 41 C1837893
UMLS 70 C1837893

Summaries for Schizophrenia 12

Disease Ontology : 12 A schizophrenia that has material basis in a mutation on chromosome 1p36.2.

MalaCards based summary : Schizophrenia 12, also known as sczd12, is related to schizophrenia and sexual disorder. An important gene associated with Schizophrenia 12 is SCZD12 (Schizophrenia 12). The drugs Dopamine and Psychotropic Drugs have been mentioned in the context of this disorder. Affiliated tissues include cortex, prefrontal cortex and small intestine.

More information from OMIM: 608543

Related Diseases for Schizophrenia 12

Symptoms & Phenotypes for Schizophrenia 12

Clinical features from OMIM®:

608543 (Updated 20-May-2021)

Drugs & Therapeutics for Schizophrenia 12

Drugs for Schizophrenia 12 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 2, Phase 3 51-61-6, 62-31-7 681
2 Psychotropic Drugs Phase 2, Phase 3
3 Dopamine Agents Phase 2, Phase 3
4 Antipsychotic Agents Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Pharmacokinetic Study of MP-214 in Patients With Schizophrenia (12 Weeks Treatment Study) Completed NCT01626859 Phase 2, Phase 3 MP-214 low dose;MP-214 middle dose;MP-214 high dose

Search NIH Clinical Center for Schizophrenia 12

Genetic Tests for Schizophrenia 12

Anatomical Context for Schizophrenia 12

MalaCards organs/tissues related to Schizophrenia 12:

40
Cortex, Prefrontal Cortex, Small Intestine, Brain, Skin

Publications for Schizophrenia 12

Articles related to Schizophrenia 12:

(show all 49)
# Title Authors PMID Year
1
Genomewide scan in families with schizophrenia from the founder population of Afrikaners reveals evidence for linkage and uniparental disomy on chromosome 1. 57
14750073 2004
2
Spinophilin expression in postmortem prefrontal cortex of schizophrenic subjects: Effects of antipsychotic treatment. 61
33257116 2021
3
Clinical effectiveness of metacognitive training as a transdiagnostic program in routine clinical settings: A prospective, multicenter, single-group study. 61
33174673 2020
4
Brain-derived neurotrophic factor as a biomarker for cognitive recovery in acute schizophrenia: 12-week results from a prospective longitudinal study. 61
29392373 2018
5
Peripheral blood gene expression of acute phase proteins in people with first episode psychosis. 61
28627459 2017
6
Proposing the short Neurological Evaluation Scale. 61
27772538 2017
7
Predictors of long term use of psychiatric services of patients with recent-onset schizophrenia: 12 years follow-up. 61
28088223 2017
8
FDG-PET scans in patients with Kraepelinian and non-Kraepelinian schizophrenia. 61
26370275 2016
9
Adjunctive selective estrogen receptor modulator increases neural activity in the hippocampus and inferior frontal gyrus during emotional face recognition in schizophrenia. 61
27138794 2016
10
Clinical pharmacology study of cariprazine (MP-214) in patients with schizophrenia (12-week treatment). 61
26834462 2016
11
Individualized differential diagnosis of schizophrenia and mood disorders using neuroanatomical biomarkers. 61
25935725 2015
12
Neurocognitive similarities between severe chronic schizophrenia and behavioural variant frontotemporal dementia. 61
25510904 2015
13
Drug attitude and other predictors of medication adherence in schizophrenia: 12 months of electronic monitoring (MEMS(®)) in the Swedish COAST-study. 61
24091164 2013
14
Patients with schizophrenia show deficits on spatial frequency doubling. 61
24140959 2013
15
Nicotine enhances antisaccade performance in schizophrenia patients and healthy controls. 61
23399382 2013
16
Integrated treatment vs. treatment-as-usual for recent onset schizophrenia; 12 year follow-up on a randomized controlled trial. 61
23898805 2013
17
Testing the genomic enrichment of a large copy number variation within schizophrenia linkage regions. 61
22914616 2012
18
Mu opioid receptor availability in people with psychiatric disorders who died by suicide: a case control study. 61
22925223 2012
19
Diagnosis of psychiatric disorders using EEG data and employing a statistical decision model. 61
21097280 2010
20
Lewy body/alpha-synucleinopathy in schizophrenia and depression: a preliminary neuropathological study. 61
19198857 2009
21
Static posed and evoked facial expressions of emotions in schizophrenia. 61
18789845 2008
22
The right profile: mismatch negativity in schizophrenia with and without auditory hallucinations as measured by a multi-feature paradigm. 61
18261954 2008
23
Randomized controlled trial of cognitive behavioral social skills training for older people with schizophrenia: 12-month follow-up. 61
17503982 2007
24
Blunted serotonergic responsivity in neuroleptic-naïve patients at first-episode of schizophrenia. 61
17204398 2007
25
Effects of atypical and typical antipsychotic treatments on sexual function in patients with schizophrenia: 12-month results from the Intercontinental Schizophrenia Outpatient Health Outcomes (IC-SOHO) study. 61
16530390 2006
26
Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophrenia. 61
16389194 2006
27
Brain anatomy in adults with velocardiofacial syndrome with and without schizophrenia: preliminary results of a structural magnetic resonance imaging study. 61
15520356 2004
28
Sex differences in functional connectivity in first-episode and chronic schizophrenia patients. 61
15337649 2004
29
[Homeless women with psychiatric disorders -- a field study]. 61
15243872 2004
30
[Distribution of latencies of visual evoked potentials in a sample of schizophrenic patients]. 61
14727371 2003
31
[Brief psychiatric hospitalization: a possible way, a strategy to evolve?]. 61
12876546 2003
32
Trait characteristic of impaired visuomotor integration during Trail-Making Test B performance in schizophrenia. 61
14504412 2003
33
Needs-based cognitive-behavioural family intervention for carers of patients suffering from schizophrenia: 12-month follow-up. 61
11722315 2001
34
An MRI study of basal ganglia volumes in first-episode schizophrenia patients treated with risperidone. 61
11282699 2001
35
Fine structure of the auditory M100 in schizophrenia and schizoaffective disorder. 61
11094145 2000
36
Durability of the effects of cognitive-behavioural therapy in the treatment of chronic schizophrenia: 12-month follow-up. 61
10616627 1999
37
[Status of psychotherapy of psychotic disorders. 12th International Symposium on Psychotherapy of Schizophrenia 12-16 October 1997 in London]. 61
9789277 1998
38
Structural evaluation of the prefrontal cortex in schizophrenia. 61
9699693 1998
39
Correlations of premorbid adjustment in schizophrenia with auditory event-related potential and neuropsychological abnormalities. 61
8831448 1996
40
Drug abuse in schizophrenic patients: clinical correlates and reasons for use. 61
1987823 1991
41
Pursuit gain and saccadic intrusions in first-degree relatives of probands with schizophrenia. 61
2266205 1990
42
Lack of relationship of auditory gating defects to negative symptoms in schizophrenia. 61
2278977 1990
43
Small intestine permeability in schizophrenia. 61
2514959 1989
44
Investigation of the associative network in schizophrenia using the semantic priming paradigm. 61
2487177 1989
45
[Anamnesis of adolescent schizophrenics. A contribution on the problem of the etiology of schizophrenia]. 61
2409587 1985
46
Serum immunoglobulin concentrations in patients admitted to an acute psychiatric in-patient service. 61
6509277 1984
47
Habituation and conditioning of skin conductance responses in children at risk. 61
7280567 1981
48
The use of the Visual Analogue Mood and Alert Scales in diagnosing hospitalized affective psychoses. 61
424482 1979
49
[Microglia-type cells in normal and pathologic human embryonic brains]. 61
465151 1979

Variations for Schizophrenia 12

Expression for Schizophrenia 12

Search GEO for disease gene expression data for Schizophrenia 12.

Pathways for Schizophrenia 12

GO Terms for Schizophrenia 12

Sources for Schizophrenia 12

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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