SCZD16
MCID: SCH061
MIFTS: 24

Schizophrenia 16 (SCZD16)

Categories: Ear diseases, Genetic diseases, Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Schizophrenia 16

MalaCards integrated aliases for Schizophrenia 16:

Name: Schizophrenia 16 57 12 13 15 70
Sczd16 57 12
Schizophrenia Susceptibility Locus, Chromosome 7q36.3-Related 57
Chromosome 7q36.3 Duplication Syndrome, 362-Kb 57

Classifications:



External Ids:

Disease Ontology 12 DOID:0070092
OMIM® 57 613959
MedGen 41 C3151408
UMLS 70 C3151408

Summaries for Schizophrenia 16

Disease Ontology : 12 A schizophrenia that has material basis in a mutation on chromosome 7q36.3.

MalaCards based summary : Schizophrenia 16, also known as sczd16, is related to schizophrenia 18 and amelogenesis imperfecta, type ig. An important gene associated with Schizophrenia 16 is VIPR2 (Vasoactive Intestinal Peptide Receptor 2), and among its related pathways/superpathways is cAMP signaling pathway. Affiliated tissues include cortex, brain and prefrontal cortex, and related phenotypes are adipose tissue and immune system

More information from OMIM: 613959

Related Diseases for Schizophrenia 16

Symptoms & Phenotypes for Schizophrenia 16

Clinical features from OMIM®:

613959 (Updated 05-Apr-2021)

MGI Mouse Phenotypes related to Schizophrenia 16:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.13 CYP19A1 PPARA VIPR2
2 immune system MP:0005387 8.92 CYP19A1 MAEA PPARA VIPR2

Drugs & Therapeutics for Schizophrenia 16

Search Clinical Trials , NIH Clinical Center for Schizophrenia 16

Genetic Tests for Schizophrenia 16

Anatomical Context for Schizophrenia 16

MalaCards organs/tissues related to Schizophrenia 16:

40
Cortex, Brain, Prefrontal Cortex, Eye, Spinal Cord

Publications for Schizophrenia 16

Articles related to Schizophrenia 16:

(show all 43)
# Title Authors PMID Year
1
Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. 57
21346763 2011
2
Acutely ill psychiatric inpatients and antimicrobial exposure. 61
33125447 2020
3
Impaired Frontal Midline Theta During Periods of High Reaction Time Variability in Schizophrenia. 61
33431347 2020
4
A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression. 61
26903267 2016
5
Elevated midline-parietal gamma band noise power in schizophrenia but not in bipolar patients. 61
26831320 2016
6
[Psychogenic depression and endogenous process (to the problem of reactive schizophrenia)]. 61
27240173 2016
7
[METABOLIC SYNDROME AND CARDIOVASCULAR RISK IN PATIENTS WITH SCHIZOPHRENIA, BIPOLAR DISORDER AND SCHIZOAFFECTIVE DISORDER]. 61
26667725 2015
8
Functional magnetic resonance spectroscopy of glutamate in schizophrenia and major depressive disorder: anterior cingulate activity during a color-word Stroop task. 61
27336037 2015
9
Can BDNF and IL-2 be indicators for the diagnosis in schizophrenic patients with depressive symptoms? 61
25241757 2014
10
Greater clinical and cognitive improvement with clozapine and risperidone associated with a thinner cortex at baseline in first-episode schizophrenia. 61
25088730 2014
11
The state of the art in European research on reducing social exclusion and stigma related to mental health: a systematic mapping of the literature. 61
24726533 2014
12
Diffusion tensor imaging study of the fornix in first episode schizophrenia and in healthy controls. 61
24837684 2014
13
Fibrillary astrocytes are decreased in the subgenual cingulate in schizophrenia. 61
24374936 2014
14
[Patients hospitalized for suicidal ideation and suicide attempt in a Mental Health Hospital: Clinicodemographical features and 6-month follow-up]. 61
25546542 2014
15
[Schizophrenia: age at disease onset]. 61
25726776 2014
16
Structural and functional reorganization of working memory system during the first decade in schizophrenia. A cross-sectional study. 61
24230490 2013
17
Connectivity and local activity within the fronto-posterior brain network in schizophrenia. 61
24053040 2013
18
Neuromagnetic auditory response and its relation to cortical thickness in ultra-high-risk for psychosis. 61
22759440 2012
19
Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy. 61
22213769 2012
20
Regional brain atrophy and functional disconnection in Broca's area in individuals at ultra-high risk for psychosis and schizophrenia. 61
23251669 2012
21
Greater white and grey matter changes associated with early cannabis use in adolescent-onset schizophrenia (AOS). 61
21388791 2011
22
Hope from the perspective of people with schizophrenia (Korea). 61
18346563 2008
23
Early nicotine withdrawal and transdermal nicotine effects on neurocognitive performance in schizophrenia. 61
17884348 2008
24
Preliminary neuropsychological findings in individuals at high genetic risk for schizophrenia. 61
21352131 2008
25
Residential mobility among patients in the VA health system: associations with psychiatric morbidity, geographic accessibility, and continuity of care. 61
17701338 2007
26
Spinal cord and related injuries after attempted suicide: psychiatric diagnosis and long-term follow-up. 61
17339888 2007
27
Social functioning in young people at risk for schizophrenia. 61
17383739 2007
28
Let's get physical: an audit of medical practice in first episode psychosis. 61
16734642 2006
29
Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. 61
15945063 2005
30
Psychiatric disorders among patients admitted to a French medical emergency service. 61
15993259 2005
31
Quality of life assessment in Turkish patients with schizophrenia and their relatives. 61
15460376 2004
32
Interstitial white matter neurons express less reelin and are abnormally distributed in schizophrenia: towards an integration of molecular and morphologic aspects of the neurodevelopmental hypothesis. 61
12931209 2003
33
Awareness and unawareness of thought disorder. 61
11185942 2000
34
Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia. 61
9989565 1999
35
Inverse relationship of perinatal complications and eye tracking dysfunction in relatives of patients with schizophrenia: evidence for a two-factor model. 61
9659870 1998
36
Immunophenotypic studies on atypical lymphocytes in psychiatric patients. 61
9541146 1998
37
Neuropsychological functioning in siblings discordant for schizophrenia and healthy volunteers. 61
8042914 1994
38
Characteristics of older adults referred to a psychiatric emergency outreach service. 61
10131296 1993
39
Saccadic intrusions into smooth pursuit in patients with schizophrenia or affective disorder and normal controls. 61
1525275 1992
40
Quantitative assessment of smooth pursuit gain and catch-up saccades in schizophrenia and affective disorders. 61
1873370 1991
41
A follow-up study of post partum illness, 1946-1978. 61
4013805 1985
42
Geropsychiatric consultation in a university hospital: a report on 67 referrals. 61
3970270 1985
43
The effect of distraction on acute schizophrenics' visual tracking. 61
728510 1978

Variations for Schizophrenia 16

Expression for Schizophrenia 16

Search GEO for disease gene expression data for Schizophrenia 16.

Pathways for Schizophrenia 16

Pathways related to Schizophrenia 16 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.96 VIPR2 PPARA

GO Terms for Schizophrenia 16

Sources for Schizophrenia 16

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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