MCID: SCH087
MIFTS: 15

Schizophrenia 18

Categories: Genetic diseases, Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Schizophrenia 18

MalaCards integrated aliases for Schizophrenia 18:

Name: Schizophrenia 18 57 12 75 29 6 73
Sczd18 57 12 75
Schizophrenia 18 with or Without an Affective Disorder 57 75
Schizophrenia Susceptibility 18 57 13
Chromosome 7q36.3 Duplication Syndrome, 362-Kb 12
Schizophrenia, Type 18 40

Classifications:



External Ids:

OMIM 57 615232
Disease Ontology 12 DOID:0070093
MeSH 44 D012559
UMLS 73 C3808913

Summaries for Schizophrenia 18

UniProtKB/Swiss-Prot : 75 Schizophrenia 18: A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder.

MalaCards based summary : Schizophrenia 18, also known as sczd18, is related to schizophrenia 16. An important gene associated with Schizophrenia 18 is SLC1A1 (Solute Carrier Family 1 Member 1).

Disease Ontology : 12 A schizophrenia that has material basis in a mutation of SLC1A1 on chromosome 9p24.2.

Description from OMIM: 615232

Related Diseases for Schizophrenia 18

Diseases in the Schizophrenia family:

Schizophrenia 1 Schizophrenia 3
Schizophrenia 4 Schizophrenia 6
Schizophrenia 5 Schizophrenia 7
Schizophrenia 8 Schizophrenia 2
Schizophrenia 9 Schizophrenia 10
Schizophrenia 11 Schizophrenia 12
Schizophrenia 14 Schizophrenia 13
Schizophrenia 15 Schizophrenia 16
Schizophrenia 18 Schizophrenia 19
Early-Onset Schizophrenia

Diseases related to Schizophrenia 18 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 schizophrenia 16 11.4

Symptoms & Phenotypes for Schizophrenia 18

Clinical features from OMIM:

615232

Drugs & Therapeutics for Schizophrenia 18

Search Clinical Trials , NIH Clinical Center for Schizophrenia 18

Genetic Tests for Schizophrenia 18

Genetic tests related to Schizophrenia 18:

# Genetic test Affiliating Genes
1 Schizophrenia 18 29 SLC1A1

Anatomical Context for Schizophrenia 18

Publications for Schizophrenia 18

Variations for Schizophrenia 18

ClinVar genetic disease variations for Schizophrenia 18:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 SLC1A1 NC_000009.12: g.4406529_4490826del84298 deletion Pathogenic GRCh37 Chromosome 9, 4406529: 4490826
2 SLC1A1 NC_000009.12: g.4406529_4490826del84298 deletion Pathogenic GRCh38 Chromosome 9, 4406529: 4490826

Expression for Schizophrenia 18

Search GEO for disease gene expression data for Schizophrenia 18.

Pathways for Schizophrenia 18

GO Terms for Schizophrenia 18

Sources for Schizophrenia 18

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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