Schizophrenia 2 (SCZD2)

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Disease Ontology 12 DOID:0070078 OMIM 58 603342 MeSH 45 D012559

MedGen 43 C1864010 UMLS 74 C1864010

UniProtKB/Swiss-Prot : ⁷⁶ Schizophrenia 2: A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder.

MalaCards based summary : Schizophrenia 2, also known as sczd2, is related to schizophrenia and perrault syndrome 1. An important gene associated with Schizophrenia 2 is SCZD2 (Schizophrenia Disorder 2), and among its related pathways/superpathways are MAPK signaling pathway and Ras signaling pathway. Related phenotypes are behavior/neurological and growth/size/body region

Disease Ontology : ¹² A schizophrenia that has material basis in an autosomal dominant mutation of SCZD2 on chromosome 11q14-q21.

Description from OMIM: 603342

Clinical features from OMIM:

603342

Search Clinical Trials , NIH Clinical Center for Schizophrenia 2

Search GEO for disease gene expression data for Schizophrenia 2.