MCID: SCH082
MIFTS: 26

Schizophrenia 5

Categories: Mental diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Schizophrenia 5

MalaCards integrated aliases for Schizophrenia 5:

Name: Schizophrenia 5 57 12 73
Schizophrenia Susceptibility Locus, Chromosome 6q-Related 57 13
Sczd5 57 12
Schizophrenia 5 with or Without an Affective Disorder 57

Classifications:



External Ids:

OMIM 57 603175
Disease Ontology 12 DOID:0070081
MedGen 42 C1864153
UMLS 73 C1864153

Summaries for Schizophrenia 5

Disease Ontology : 12 A schizophrenia that has material basis in a mutation on chromosome 6q13-q26.

MalaCards based summary : Schizophrenia 5, also known as schizophrenia susceptibility locus, chromosome 6q-related, is related to schizophrenia and fibromyalgia. An important gene associated with Schizophrenia 5 is SCZD5 (Schizophrenia Disorder 5), and among its related pathways/superpathways are Monoamine GPCRs and GPCRs, Other.

Description from OMIM: 603175

Related Diseases for Schizophrenia 5

Graphical network of the top 20 diseases related to Schizophrenia 5:



Diseases related to Schizophrenia 5

Symptoms & Phenotypes for Schizophrenia 5

Clinical features from OMIM:

603175

Drugs & Therapeutics for Schizophrenia 5

Search Clinical Trials , NIH Clinical Center for Schizophrenia 5

Genetic Tests for Schizophrenia 5

Anatomical Context for Schizophrenia 5

Publications for Schizophrenia 5

Variations for Schizophrenia 5

Expression for Schizophrenia 5

Search GEO for disease gene expression data for Schizophrenia 5.

Pathways for Schizophrenia 5

GO Terms for Schizophrenia 5

Cellular components related to Schizophrenia 5 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 8.92 DRD3 HTR2A HTR3A HTR6

Biological processes related to Schizophrenia 5 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to ethanol GO:0045471 9.43 DRD3 HTR3A
2 chemical synaptic transmission GO:0007268 9.43 HTR2A HTR3A HTR6
3 cellular calcium ion homeostasis GO:0006874 9.4 DRD3 HTR2A
4 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.37 HTR2A HTR6
5 response to cocaine GO:0042220 9.32 DRD3 HTR3A
6 G-protein coupled serotonin receptor signaling pathway GO:0098664 9.16 HTR2A HTR6
7 behavioral response to cocaine GO:0048148 8.96 DRD3 HTR2A
8 regulation of dopamine secretion GO:0014059 8.62 DRD3 HTR2A

Molecular functions related to Schizophrenia 5 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 9.26 DRD3 HTR2A
2 neurotransmitter receptor activity GO:0030594 9.16 HTR2A HTR6
3 G-protein coupled serotonin receptor activity GO:0004993 8.96 HTR2A HTR6
4 serotonin binding GO:0051378 8.62 HTR2A HTR3A

Sources for Schizophrenia 5

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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