MCID: SCH001
MIFTS: 24

Schwannoma of Twelfth Cranial Nerve

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Schwannoma of Twelfth Cranial Nerve

MalaCards integrated aliases for Schwannoma of Twelfth Cranial Nerve:

Name: Schwannoma of Twelfth Cranial Nerve 12 15
Schwannoma of the Twelfth Cranial Nerve 72
Hypoglossal Schwannoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3197
NCIt 50 C5434
UMLS 72 C1335928

Summaries for Schwannoma of Twelfth Cranial Nerve

Disease Ontology : 12 A neurilemmoma that is located in the 12th cranial nerve.

MalaCards based summary : Schwannoma of Twelfth Cranial Nerve, also known as schwannoma of the twelfth cranial nerve, is related to neurilemmoma and plexiform schwannoma. An important gene associated with Schwannoma of Twelfth Cranial Nerve is NF2 (Neurofibromin 2), and among its related pathways/superpathways are Neuroscience and Glioblastoma Multiforme. Affiliated tissues include tongue and 12th cranial nerve, and related phenotypes are Decreased cell migration and Increased cell migration

Related Diseases for Schwannoma of Twelfth Cranial Nerve

Graphical network of the top 20 diseases related to Schwannoma of Twelfth Cranial Nerve:



Diseases related to Schwannoma of Twelfth Cranial Nerve

Symptoms & Phenotypes for Schwannoma of Twelfth Cranial Nerve

GenomeRNAi Phenotypes related to Schwannoma of Twelfth Cranial Nerve according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 8.96 NF1 NF2
2 Increased cell migration GR00055-A-3 8.62 NF1 NF2

Drugs & Therapeutics for Schwannoma of Twelfth Cranial Nerve

Search Clinical Trials , NIH Clinical Center for Schwannoma of Twelfth Cranial Nerve

Genetic Tests for Schwannoma of Twelfth Cranial Nerve

Anatomical Context for Schwannoma of Twelfth Cranial Nerve

MalaCards organs/tissues related to Schwannoma of Twelfth Cranial Nerve:

41
Tongue

The Foundational Model of Anatomy Ontology organs/tissues related to Schwannoma of Twelfth Cranial Nerve:

19
12th Cranial Nerve

Publications for Schwannoma of Twelfth Cranial Nerve

Articles related to Schwannoma of Twelfth Cranial Nerve:

(show all 43)
# Title Authors PMID Year
1
Muscular-stage Dissection during Far Lateral Approach and Its Transcondylar Extension. 38
30210990 2018
2
Single-stage total resection of giant dumbbell-shaped hypoglossal schwannoma: a case report. 38
29285680 2018
3
Hypoglossal Schwannoma of Neck: Case Report and Review of Literature. 38
29175571 2018
4
Hypofractionated stereotactic radiotherapy for dumbbell-shaped hypoglossal schwannomas: Two cases of long-term follow-up and a review of the literature. 38
27446582 2016
5
Giant recurrent dumbbell-shaped hypoglossal schwannoma in an elderly male: A case report. 38
26870204 2016
6
Hypoglossal schwannoma of parapharyngeal space: an unusual case report. 38
25838673 2015
7
Spatial Relationship between Hypoglossal Schwannoma and the Vertebral Artery Using the Far-Lateral Approach. 38
26345663 2015
8
Diffuse cerebral vasospasm following resection of a hypoglossal schwannoma in a child. 38
24350734 2014
9
Management of hypoglossal schwannomas: single institutional experience of 14 cases. 38
25072009 2014
10
Spontaneous regression of a cystic hypoglossal schwannoma causing unilateral tongue atrophy. 38
23855391 2014
11
Acute brainstem compression by intratumoral hemorrhages in an intracranial hypoglossal schwannoma. 38
23541888 2013
12
Hypoglossal schwannoma presenting as hemi-atrophy of the tongue. 38
23860167 2013
13
Plexiform hypoglossal schwannoma of the tongue and the submandibular region. 38
22976661 2012
14
Isolated hypoglossal schwannoma in a 9-year-old child. 38
22725844 2012
15
Surgical treatment of dumbbell-shaped hypoglossal schwannoma via a pure endoscopic transoral approach. 38
22009014 2012
16
Hypoglossal schwannoma masquerading as a carotid body tumor. 38
23213586 2012
17
Hypoglossal nerve schwannoma with intratumoral hemorrhage. 38
21837502 2012
18
Endoscopic transoral approach for extracranial hypoglossal schwannoma. 38
21876364 2011
19
Intraoperative monitoring during surgery for hypoglossal schwannoma. 38
20488709 2010
20
Large cystic hypoglossal schwannoma with fluid-fluid level: a case report. 38
21318038 2010
21
Hypoglossal schwannoma presenting only with headache. 38
20098193 2010
22
[Surgical strategy for hypoglossal schwannoma]. 38
20085098 2010
23
Hypoglossal schwannoma-successful reinnervation and functional recovery of the tongue following tumour removal and nerve grafting. 38
19290472 2009
24
Isolated unilateral hypoglossal nerve palsy secondary to an atlantooccipital joint juxtafacet synovial cyst. 38
19320583 2009
25
Extradural dumbbell schwannoma of the hypoglossal nerve: a case report with review of the literature. 38
18423539 2008
26
Intradural microsurgery and extradural gamma knife surgery for hypoglossal schwannoma: case report and review of the literature. 38
18210363 2007
27
Hypoglossal schwannoma presenting as hemi-atrophy of the tongue. 38
17486732 2007
28
[MRI performance and diagnosis of schwannomas from cranial nerves in posterior cranial fossae]. 38
16965666 2006
29
Usefulness of transcervical approach for surgical treatment of hypoglossal schwannoma with paraspinal extension: case report. 38
16531208 2006
30
Dumbbell-shaped hypoglossal schwannoma in an elderly woman: a clinical dilemma. 38
15936371 2005
31
Navigated dorsolateral suboccipital transcondylar (NADOSTA) approach for treatment of hypoglossal schwannoma. Case report and review of the literature. 38
15823681 2005
32
Bilateral hypoglossal schwannoma: a radiologic diagnosis. 38
16010098 2004
33
Extracranial hypoglossal schwannoma. 38
12821768 2003
34
Dumbbell-shaped hypoglossal schwannoma. A case report. 38
12670602 2003
35
Stereotactic radiosurgery: the preferred management for patients with nonvestibular schwannomas? 38
11958895 2002
36
Health-related quality of life in patients with skull base tumours. 38
11926460 2002
37
Hypoglossal schwannoma in the submandibular space. 38
11860659 2002
38
Hypoglossal schwannoma: an uncommon cause of twelfth-nerve palsy. 38
10846888 2000
39
Hemorrhagic necrotic schwannoma presenting as purulent meningitis. 38
9604141 1998
40
Surgical management of transcranial hypoglossal schwannomas. 38
8588644 1995
41
Hypoglossal schwannoma. 38
7771724 1995
42
Hemiatrophy of the tongue due to hypoglossal schwannoma shown by MRI. 38
8041451 1994
43
Intracranial hypoglossal schwannoma as an unusual cause of facial nerve palsy. Case report. 38
7057241 1982

Variations for Schwannoma of Twelfth Cranial Nerve

Expression for Schwannoma of Twelfth Cranial Nerve

Search GEO for disease gene expression data for Schwannoma of Twelfth Cranial Nerve.

Pathways for Schwannoma of Twelfth Cranial Nerve

Pathways related to Schwannoma of Twelfth Cranial Nerve according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.49 NF2 NF1
2 10.67 NF2 NF1

GO Terms for Schwannoma of Twelfth Cranial Nerve

Biological processes related to Schwannoma of Twelfth Cranial Nerve according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.43 NF2 NF1
2 brain development GO:0007420 9.4 NF2 NF1
3 regulation of cell proliferation GO:0042127 9.37 NF2 NF1
4 actin cytoskeleton organization GO:0030036 9.32 NF2 NF1
5 negative regulation of cell migration GO:0030336 9.26 NF2 NF1
6 negative regulation of protein kinase activity GO:0006469 9.16 NF2 NF1
7 negative regulation of MAPK cascade GO:0043409 8.96 NF2 NF1
8 negative regulation of cell-matrix adhesion GO:0001953 8.62 NF2 NF1

Sources for Schwannoma of Twelfth Cranial Nerve

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62 PubMed
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73 UMLS via Orphanet
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