MCID: SCT001
MIFTS: 26

Sciatic Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Sciatic Neuropathy

MalaCards integrated aliases for Sciatic Neuropathy:

Name: Sciatic Neuropathy 12 44 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11446
MeSH 44 D020426
SNOMED-CT 67 52585001
UMLS 71 C0149940

Summaries for Sciatic Neuropathy

MalaCards based summary : Sciatic Neuropathy is related to mononeuropathy and peripheral nervous system disease, and has symptoms including sciatica An important gene associated with Sciatic Neuropathy is TMEM119 (Transmembrane Protein 119). Affiliated tissues include brain, spinal cord and kidney.

Related Diseases for Sciatic Neuropathy

Diseases related to Sciatic Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 75)
# Related Disease Score Top Affiliating Genes
1 mononeuropathy 29.7 TRPV1 SH3TC2 PMP22
2 peripheral nervous system disease 29.7 TRPV1 SH3TC2 PMP22
3 neuropathy, hereditary, with liability to pressure palsies 29.6 SH3TC2 PMP22
4 neuropathy 10.9
5 foot drop 10.3
6 paresthesia 10.2
7 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 10.1
8 compartment syndrome 10.1
9 ocular motor apraxia 10.0
10 thrombosis 10.0
11 radiculopathy 10.0
12 spinal stenosis 10.0
13 charcot-marie-tooth disease type x 10.0 SH3TC2 PMP22
14 charcot-marie-tooth disease, type 4b3 10.0 SH3TC2 PMP22
15 charcot-marie-tooth disease, x-linked dominant, 1 10.0 SH3TC2 PMP22
16 charcot-marie-tooth disease, axonal, type 2d 10.0 SH3TC2 PMP22
17 charcot-marie-tooth disease, demyelinating, type 1b 10.0 SH3TC2 PMP22
18 charcot-marie-tooth disease, demyelinating, type 1c 10.0 SH3TC2 PMP22
19 charcot-marie-tooth disease, demyelinating, type 1a 10.0 SH3TC2 PMP22
20 carpal tunnel syndrome 9.9 SH3TC2 PMP22
21 motor peripheral neuropathy 9.9 SH3TC2 PMP22
22 hypertrophic neuropathy of dejerine-sottas 9.9 SH3TC2 PMP22
23 aortic aneurysm, familial abdominal, 1 9.8
24 klippel-trenaunay-weber syndrome 9.8
25 lipomatosis, multiple 9.8
26 osteogenic sarcoma 9.8
27 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.8
28 diffuse large b-cell lymphoma 9.8
29 lymphoma 9.8
30 pleomorphic lipoma 9.8
31 arteriovenous malformation 9.8
32 gestational diabetes 9.8
33 enterocele 9.8
34 quadriplegia 9.8
35 ehlers-danlos syndrome 9.8
36 frozen shoulder 9.8
37 neuritis 9.8
38 acromegaly 9.8
39 hemangioma 9.8
40 myoma 9.8
41 capillary hemangioma 9.8
42 endometriosis 9.8
43 bursitis 9.8
44 neurilemmoma 9.8
45 complex regional pain syndrome 9.8
46 rhabdomyosarcoma 9.8
47 aortic aneurysm 9.8
48 plexopathy 9.8
49 peroneal neuropathy 9.8
50 perineurioma 9.8

Graphical network of the top 20 diseases related to Sciatic Neuropathy:



Diseases related to Sciatic Neuropathy

Symptoms & Phenotypes for Sciatic Neuropathy

UMLS symptoms related to Sciatic Neuropathy:


sciatica

Drugs & Therapeutics for Sciatic Neuropathy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effectiveness of Physical Therapy as an Adjunct to a Selective Nerve Root Block in the Treatment of Lumbar Radicular Pain From Disk Herniation Completed NCT00934284 Phase 2
2 Neuromuscular Ultrasound for Focal Neuropathies Completed NCT01394822
3 Prospective, Multi-center, Cohort Study of the Cost Effectiveness of Osteopathic Manipulative Treatment for Chronic Low Back Pain Completed NCT03532230

Search NIH Clinical Center for Sciatic Neuropathy

Cochrane evidence based reviews: sciatic neuropathy

Genetic Tests for Sciatic Neuropathy

Anatomical Context for Sciatic Neuropathy

MalaCards organs/tissues related to Sciatic Neuropathy:

40
Brain, Spinal Cord, Kidney, Breast, Thalamus

Publications for Sciatic Neuropathy

Articles related to Sciatic Neuropathy:

(show top 50) (show all 190)
# Title Authors PMID Year
1
Radiofrequency ablation vs microwave ablation for osteoid osteomas: long-term results. 61
32564104 2020
2
The persistent sciatic artery: Report of ten cases. 61
32862980 2020
3
Circumferential Adipose Lesion of the Sciatic Nerve. 61
32407922 2020
4
Ultrasound imaging and guidance in the management of post-injection sciatic neuropathy: Love, loss and space. 61
32760903 2020
5
Reply to the Letter to the Editor for "Use of fluoroscopic-guided transsacral block for the treatment of iatrogenic post-injection sciatic neuropathy: Report of three cases". 61
32760904 2020
6
Tibialis posterior (TP) tendon transfer for foot drop: A single center experience. 61
32405209 2020
7
Pediatric sciatic neuropathy: Clinical presentation and long term follow up. 61
32730417 2020
8
Sciatic neuropathy after normal vaginal delivery: A case report. 61
31822439 2020
9
Sciatic neuropathy in an acromegalic cat without concurrent diabetes mellitus. 61
32128232 2020
10
[Treatment of sciatic posttraumatic neuropathy with chronic neuromodulation and endoscopic technics]. 61
33095534 2020
11
A case of solitary rectal diverticulum presenting with a large retrorectal abscess. 61
31890199 2020
12
Intraneural Ganglion Cyst of the Sciatic Nerve Treated Using Arthroscopic Hip Surgery: A Case Report. 61
30690884 2019
13
Use of fluoroscopic-guided transsacral block for the treatment of iatrogenic post-injection sciatic neuropathy: Report of three cases. 61
31893279 2019
14
Isolated injury to the tibial division of sciatic nerve after self-massage of the gluteal muscle with massage ball: A case report. 61
31083184 2019
15
Targeting the β2-integrin LFA-1, reduces adverse neuroimmune actions in neuropathic susceptibility caused by prenatal alcohol exposure. 61
30961664 2019
16
Clinical and Electrodiagnostic Features Of Nontraumatic Sciatic Neuropathy. 61
30414322 2019
17
Stimulation Contractility Gradient of a Neuromuscular Choristoma Within the Sciatic Nerve: 2-Dimensional Operative Video. 61
29800277 2019
18
MRI of Foot Drop: How We Do It. 61
30152741 2018
19
A Central Nervous System Tumor Mimicking a Lumbar Spine Pathology Causing Acute Foot Drop: A Case Report. 61
30740383 2018
20
Bilateral sciatic neuropathy with severe rhabdomyolysis following venlafaxine overdose: A case report. 61
30212953 2018
21
Sciatic neuropathy caused by a pressure ulcer: A case report. 61
30200159 2018
22
Utility of Magnetic Resonance Imaging for Predicting Severity of Sciatic Nerve Injury. 61
29659424 2018
23
Post-operative extra-spinal etiologies of sciatic nerve impingement. 61
29423723 2018
24
Sciatic neuropathy and rhabdomyolysis after carbon monoxide intoxication: A case report. 61
29879074 2018
25
Sciatic neurosteatosis: Relationship with age, gender, obesity and height. 61
29063256 2018
26
Bilateral Sciatic Neuropathy following Gluteal Augmentation With Autologous Fat Grafting. 61
29707455 2018
27
Gluteal compartment syndrome with neurologic impairment: Report of 2 cases and review of the literature. 61
28224633 2018
28
Segmentation of Peripheral Nerves From Magnetic Resonance Neurography: A Fully-Automatic, Deep Learning-Based Approach. 61
30283397 2018
29
Clinical and Genetic Analysis of an Asian Indian Family with Charcot-Marie-Tooth Disease Type 4C. 61
29515423 2018
30
Prenatal alcohol exposure is a risk factor for adult neuropathic pain via aberrant neuroimmune function. 61
29258553 2017
31
Sciatic neuropathy due to popliteal fossa nerve block. 61
28214338 2017
32
Management of refractory sciatic neuropathic pain using ultrasound-guided pulsed radiofrequency. 61
28946529 2017
33
Synovial cyst of the knee: A rare case of acute sciatic neuropathy. 61
27659236 2017
34
Sciatic neuropathy: findings on magnetic resonance neurography. 61
28670031 2017
35
Observational multicentric study on chronic sciatic pain: clinical data from 44 Italian centers. 61
28429339 2017
36
Preventing Sciatic Nerve Injury due to Intramuscular Injection: Ten-Year Single-Center Experience and Literature Review. 61
27593812 2017
37
Chronic Sciatic Neuropathy in Rat Reduces Voluntary Wheel-Running Activity With Concurrent Chronic Mechanical Allodynia. 61
27782944 2017
38
Bilateral Sciatic Neuropathy after an Autologous Breast Reconstruction in a Massive Weight Loss Patient. 61
28203505 2017
39
Isolated sciatic neuropathy as an initial manifestation of a high grade B-cell lymphoma: A case report and literature review. 61
27540756 2016
40
Is diffusion tensor imaging useful in the assessment of the sciatic nerve and its pathologies? Our clinical experience. 61
27459247 2016
41
Early diagnosis of Varicella-zoster virus sciatic neuropathy by MRI neurography. 61
27625277 2016
42
Sequential early and delayed painful sciatic neuropathy following revision total hip arthroplasty. 61
26990207 2016
43
Irreversible electroporation-induced sciatic neuropathy observed by intraoperative neuromonitoring. 61
27417051 2016
44
Postpartum sciatic neuropathy: Segmental fractional anisotropy analysis to disclose neurapraxia. 61
27572428 2016
45
Tissue-engineered conduit promotes sciatic nerve regeneration following radiation-induced injury as monitored by magnetic resonance imaging. 61
26686023 2016
46
Nerve Wrapping of the Sciatic Nerve With Acellular Dermal Matrix in Chronic Complete Proximal Hamstring Ruptures and Ischial Apophyseal Avulsion Fractures. 61
27081655 2016
47
Sciatic Neuropathy Caused by Focal Venous Engorgement Associated With Deep Vein Thrombosis: A Case Report. 61
26079864 2016
48
Sciatic neuropathy developed after injection during curettage. 61
27225613 2016
49
Preventive Effects of the Chinese Herbal Medicine Prescription Tangkuei Decoction for Frigid Extremities on Sciatic Neuropathy in Streptozotocin-Induced Diabetic Rats. 61
27057201 2016
50
Leg Weakness Caused by Bilateral Piriformis Syndrome: A Case Report. 61
26798622 2015

Variations for Sciatic Neuropathy

Expression for Sciatic Neuropathy

Search GEO for disease gene expression data for Sciatic Neuropathy.

Pathways for Sciatic Neuropathy

GO Terms for Sciatic Neuropathy

Biological processes related to Sciatic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to ATP GO:0071318 8.62 TRPV1 CIB2

Sources for Sciatic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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