MCID: SCR009
MIFTS: 23

Scirrhous Adenocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Scirrhous Adenocarcinoma

MalaCards integrated aliases for Scirrhous Adenocarcinoma:

Name: Scirrhous Adenocarcinoma 12 15
Adenocarcinoma, Scirrhous 44 73
Adenocarcinoma with Productive Fibrosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4024
MeSH 44 D002293
NCIt 50 C2928
SNOMED-CT 68 4584002
UMLS 73 C0007135

Summaries for Scirrhous Adenocarcinoma

Disease Ontology : 12 An adenocarcinoma that results in a hard structure owing to the formation of dense connective tissue in the stroma.

MalaCards based summary : Scirrhous Adenocarcinoma, also known as adenocarcinoma, scirrhous, is related to adenocarcinoma and breast apocrine carcinoma. An important gene associated with Scirrhous Adenocarcinoma is PGR (Progesterone Receptor), and among its related pathways/superpathways are Gastric cancer and Signaling by ERBB4. Affiliated tissues include pancreas, liver and colon.

Related Diseases for Scirrhous Adenocarcinoma

Diseases related to Scirrhous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 10.3
2 breast apocrine carcinoma 9.9 ERBB2 PGR
3 glassy cell carcinoma of the cervix 9.9 ERBB2 PGR
4 breast mucoepidermoid carcinoma 9.9 ERBB2 PGR
5 breast metaplastic carcinoma 9.9 ERBB2 PGR
6 intracystic papillary adenoma 9.9 ERBB2 PGR
7 progesterone-receptor negative breast cancer 9.9 ERBB2 PGR
8 breast medullary carcinoma 9.9 ERBB2 PGR
9 breast scirrhous carcinoma 9.9 ERBB2 PGR
10 progesterone-receptor positive breast cancer 9.9 ERBB2 PGR
11 oncocytic breast carcinoma 9.9 ERBB2 PGR
12 apocrine adenocarcinoma 9.9 ERBB2 PGR
13 uterine body mixed cancer 9.9 ERBB2 PGR
14 type i 9.9
15 breast adenoid cystic carcinoma 9.9 ERBB2 PGR
16 breast squamous cell carcinoma 9.9 ERBB2 PGR
17 microglandular adenosis 9.9 ERBB2 PGR
18 uterine corpus cancer 9.9 ERBB2 PGR
19 luminal breast carcinoma 9.8 ERBB2 PGR
20 breast benign neoplasm 9.8 ERBB2 PGR
21 thoracic benign neoplasm 9.8 ERBB2 PGR
22 inflammatory breast carcinoma 9.8 ERBB2 PGR
23 mixed cell type cancer 9.8 ERBB2 PGR
24 lipid-rich carcinoma 9.8 ERBB2 PGR
25 breast secretory carcinoma 9.8 ERBB2 PGR
26 mammary paget's disease 9.8 ERBB2 PGR
27 bilateral breast cancer 9.8 ERBB2 PGR
28 primary peritoneal carcinoma 9.8 ERBB2 PGR
29 tubular adenocarcinoma 9.8 ERBB2 PGR
30 breast papillary carcinoma 9.8 ERBB2 PGR
31 pre-malignant neoplasm 9.8 ERBB2 PGR
32 fallopian tube carcinoma 9.8 ERBB2 PGR
33 papillary adenocarcinoma 9.8 ERBB2 PGR
34 sweat gland cancer 9.8 ERBB2 PGR
35 estrogen-receptor negative breast cancer 9.8 ERBB2 PGR
36 in situ carcinoma 9.8 ERBB2 PGR
37 breast fibroadenoma 9.8 ERBB2 PGR
38 malignant ovarian surface epithelial-stromal neoplasm 9.8 ERBB2 PGR
39 ovary epithelial cancer 9.7 ERBB2 PGR
40 breast carcinoma in situ 9.7 ERBB2 PGR
41 female breast cancer 9.7 ERBB2 PGR
42 serous cystadenocarcinoma 9.7 ERBB2 PGR
43 estrogen-receptor positive breast cancer 9.7 ERBB2 PGR
44 cystadenocarcinoma 9.7 ERBB2 PGR
45 endometrial adenocarcinoma 9.7 ERBB2 PGR
46 sporadic breast cancer 9.7 ERBB2 PGR
47 ductal carcinoma in situ 9.6 ERBB2 PGR
48 ovarian serous cystadenocarcinoma 9.6 ERBB2 PGR
49 female reproductive organ cancer 9.6 ERBB2 PGR
50 breast disease 9.6 ERBB2 PGR

Graphical network of the top 20 diseases related to Scirrhous Adenocarcinoma:



Diseases related to Scirrhous Adenocarcinoma

Symptoms & Phenotypes for Scirrhous Adenocarcinoma

Drugs & Therapeutics for Scirrhous Adenocarcinoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase II Study to Evaluate Efficacy and Safety of Dovitinib (TKI258) in Advanced Scirrhous Gastric Carcinoma Patients Completed NCT01576380 Phase 2 TKI258

Search NIH Clinical Center for Scirrhous Adenocarcinoma

Cochrane evidence based reviews: adenocarcinoma, scirrhous

Genetic Tests for Scirrhous Adenocarcinoma

Anatomical Context for Scirrhous Adenocarcinoma

MalaCards organs/tissues related to Scirrhous Adenocarcinoma:

41
Pancreas, Liver, Colon

Publications for Scirrhous Adenocarcinoma

Articles related to Scirrhous Adenocarcinoma:

# Title Authors Year
1
Scirrhous adenocarcinoma of the rectum in a cow. ( 8117809 )
1993
2
Immunohistochemical identification of type I procollagen in tumour cells of scirrhous adenocarcinoma of the stomach. ( 2831927 )
1988
3
Primary scirrhous adenocarcinoma of the colon (signet-ring cell type). ( 6274043 )
1981
4
CO-EXISTENT CYSTOSARCOMA PHYLLODES AND SCIRRHOUS ADENOCARCINOMA OF THE BREAST. ( 14080403 )
1963
5
Scirrhous adenocarcinoma arising in a lipomatous pseudohypertrophic pancreas. ( 14441042 )
1960
6
CLINICOPATHOLOGIC conference: scirrhous adenocarcinoma of bile duct with metastases and biliary cirrhosis of liver. ( 13078623 )
1953
7
WEEKLY clinicopathological exercise: scirrhous adenocarcinoma of pancreas with metastases to the liver. ( 14910848 )
1952
8
WEEKLY clinicopathological exercises: scirrhous adenocarcinoma of pancreas. ( 14882472 )
1951

Variations for Scirrhous Adenocarcinoma

Expression for Scirrhous Adenocarcinoma

Search GEO for disease gene expression data for Scirrhous Adenocarcinoma.

Pathways for Scirrhous Adenocarcinoma

Pathways related to Scirrhous Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.62 ERBB2 PGR
2
Show member pathways
10.66 ERBB2 PGR

GO Terms for Scirrhous Adenocarcinoma

Sources for Scirrhous Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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