MCID: SCL015
MIFTS: 48

Scleritis

Categories: Eye diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Scleritis

MalaCards integrated aliases for Scleritis:

Name: Scleritis 12 20 44 15 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:13452
ICD9CM 34 379.00
MeSH 44 D015423
NCIt 50 C119046
SNOMED-CT 67 155201000
ICD10 32 H15.0
UMLS 71 C0036416

Summaries for Scleritis

MalaCards based summary : Scleritis is related to posterior scleritis and anterior scleritis. An important gene associated with Scleritis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Hormones and Hormone Antagonists have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and neutrophil, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 74 Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as... more...

Related Diseases for Scleritis

Diseases in the Scleritis family:

Posterior Scleritis Anterior Scleritis

Diseases related to Scleritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 792)
# Related Disease Score Top Affiliating Genes
1 posterior scleritis 31.7 TNF PRTN3 CRP
2 anterior scleritis 31.3 TNF PRTN3 IL1RAPL2 CRP
3 uveitis 31.1 TNF IL4 IFNG CTLA4 CCL2
4 retinal detachment 31.0 TNF MMP9 IFNG CCL2
5 keratitis, hereditary 31.0 TNF MMP9 CCR6
6 herpes zoster 30.5 TNF IFNG CCR6
7 systemic autoimmune disease 30.4 MMP9 CRP
8 endophthalmitis 30.4 TNF SELE CRP
9 retinal vasculitis 30.4 TNF CCR6 CCL2
10 intermediate uveitis 30.3 TNF IFNG CCR6
11 mycobacterium tuberculosis 1 30.2 TNF IL4 IFNG CCR6
12 toxoplasmosis 30.2 TNF IL5 IL4 IFNG
13 relapsing polychondritis 30.2 IFNG CRP CCL2
14 lepromatous leprosy 30.2 TNF IL4 IFNG
15 lupus erythematosus 30.1 TNF PTPN22 IFNG CTLA4
16 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 30.1 PTPN22 IFNG CTLA4
17 panuveitis 30.0 TNF CRP CCR6
18 chorioretinitis 30.0 TNF IFNG CRP
19 posterior uveitis 30.0 TNF IL5 IL4 IFNG CCR6
20 pyoderma 30.0 TNF MMP9 ITGB2 CCR6
21 pyoderma gangrenosum 30.0 TNF MMP9 ITGB2 CCR6
22 eales disease 30.0 TNF IL4 IFNG
23 crohn's colitis 29.9 TNF IFNG CCR6
24 neuritis 29.9 TNF MMP9 IL4 IFNG CCL2
25 hypopyon 29.9 TNF CRP
26 eye disease 29.9 TNF IL5 IL4 IFNG CCR6 CCL2
27 rheumatoid vasculitis 29.9 TNF SELE
28 igg4-related disease 29.8 IL4 CRP CCR6
29 vitiligo-associated multiple autoimmune disease susceptibility 1 29.8 PTPN22 CTLA4 CCR6
30 cellulitis 29.8 TNF IL5 CRP CCR6
31 myasthenia gravis 29.8 TNF IL4 IFNG CTLA4
32 nocardiosis 29.7 TNF IFNG CRP
33 allergic conjunctivitis 29.7 TNF IL5 IL4 IFNG
34 lyme disease 29.7 TNF MMP9 CRP
35 histiocytosis 29.7 TNF IFNG CCR6
36 histoplasmosis 29.7 TNF IFNG CCR6
37 spondylitis 29.7 TNF IFNG CRP CCR6
38 orbital plasma cell granuloma 29.7 PRTN3 CTLA4 CRP
39 pulmonary tuberculosis 29.7 TNF IL4 IFNG CCL2
40 enterocolitis 29.7 TNF CRP
41 toxocariasis 29.6 IL5 IL4 CRP
42 syphilis 29.6 PRTN3 CRP CCR6
43 spondyloarthropathy 29.6 TNF SELE IL4 IFNG CCL2
44 sarcoidosis 1 29.6 TNF IFNG CRP CCR6 CCL2
45 iritis 29.6 TNF CRP CCR6
46 enthesopathy 29.6 TNF CRP CCR6
47 neutrophilic dermatosis, acute febrile 29.6 TNF MPO CRP
48 panophthalmitis 29.6 IFNG CRP
49 conjunctivitis 29.6 TNF MPO MMP9 IL5 IL4 IFNG
50 juvenile rheumatoid arthritis 29.6 TNF IFNG CTLA4 CRP CCL2

Comorbidity relations with Scleritis via Phenotypic Disease Network (PDN):


Rheumatoid Arthritis

Graphical network of the top 20 diseases related to Scleritis:



Diseases related to Scleritis

Symptoms & Phenotypes for Scleritis

MGI Mouse Phenotypes related to Scleritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.18 CCR6 CTLA4 IFNG IL22 IL4 IL5
2 homeostasis/metabolism MP:0005376 10.13 CCR6 CRP CTLA4 IFNG IL22 IL4
3 immune system MP:0005387 10.13 CCL2 CCR6 CRP CTLA4 IFNG IL22
4 digestive/alimentary MP:0005381 10.01 CTLA4 IFNG IL22 IL4 IL5 MMP9
5 integument MP:0010771 9.76 CTLA4 IFNG IL22 IL4 ITGB2 MMP9
6 liver/biliary system MP:0005370 9.56 CTLA4 IFNG IL22 IL4 IL5 PTPN22
7 respiratory system MP:0005388 9.28 CTLA4 IFNG IL22 IL4 IL5 MMP9

Drugs & Therapeutics for Scleritis

Drugs for Scleritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 64)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Hormones Phase 4
2 Hormone Antagonists Phase 4
3 Melanocyte-Stimulating Hormones Phase 4
4 Adrenocorticotropic Hormone Phase 4
5 beta-Endorphin Phase 4
6
Infliximab Approved Phase 3 170277-31-3
7
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
8
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
9
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
10 Gastrointestinal Agents Phase 3
11 Immunosuppressive Agents Phase 3
12 Antirheumatic Agents Phase 3
13 Dermatologic Agents Phase 3
14 Immunologic Factors Phase 3
15 Alkylating Agents Phase 3
16
rituximab Approved Phase 1, Phase 2 174722-31-7 10201696
17
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
18
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 5284616 6436030
19
Clotrimazole Approved, Vet_approved Phase 1, Phase 2 23593-75-1 2812
20
Tofacitinib Approved, Investigational Phase 2 477600-75-2
21 Antineoplastic Agents, Immunological Phase 1, Phase 2
22 Antifungal Agents Phase 1, Phase 2
23 Antibiotics, Antitubercular Phase 1, Phase 2
24 Anti-Infective Agents Phase 1, Phase 2
25 Anti-Bacterial Agents Phase 1, Phase 2
26 Neurotransmitter Agents Phase 2
27 Endorphins Phase 2
28 Protein Kinase Inhibitors Phase 2
29
Dexamethasone Approved, Investigational, Vet_approved Phase 1 50-02-2 5743
30
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 1 1177-87-3
31 Anti-Inflammatory Agents Phase 1
32 Ophthalmic Solutions Phase 1
33 BB 1101 Phase 1
34 Antineoplastic Agents, Hormonal Phase 1
35 HIV Protease Inhibitors Phase 1
36
protease inhibitors Phase 1
37 Dexamethasone 21-phosphate Phase 1
38 Pharmaceutical Solutions Phase 1
39 Antiemetics Phase 1
40 glucocorticoids Phase 1
41
Levoleucovorin Approved, Investigational 68538-85-2 149436
42 Prednisolone acetate Approved, Vet_approved 52-21-1
43
Prednisolone Approved, Vet_approved 50-24-8 5755
44
Adalimumab Approved, Experimental 331731-18-1 16219006
45
Mycophenolic acid Approved 24280-93-1 446541
46
Methylprednisolone hemisuccinate Approved 2921-57-5
47
Azathioprine Approved 446-86-6 2265
48
Etanercept Approved, Investigational 185243-69-0
49
Methylprednisolone Approved, Vet_approved 83-43-2 6741
50
Prednisolone phosphate Approved, Vet_approved 302-25-0

Interventional clinical trials:

(show all 16)
# Name Status NCT ID Phase Drugs
1 Prospective Open Label Study of H.P. Acthar Gel Injection in Patients With Active Non-Infectious Uveitis With Associated Glaucoma Thus High Frequency Regional Corticosteroid and Oral Corticosteroids Cause Intolerable Side-Effects Completed NCT02764697 Phase 4 H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
2 A Multicenter Randomized Open-label Trial Comparing the Efficacy and Safety of Infliximab Versus Cyclophosphamide in Subjects With Idiopathic Refractory Scleritis Recruiting NCT03088293 Phase 3 Infliximab;Cyclophosphamide
3 Gevokizumab Treatment for Active Scleritis By IL-1 Inhibition (GATSBY) Completed NCT01835132 Phase 1, Phase 2
4 A PhaseI/II Prospective, Randomized, Dose-Ranging Pilot Study of Rituximab in the Treatment of Refractory Scleritis and Non-Infectious Orbital Inflammation Completed NCT00415506 Phase 1, Phase 2 Rituximab
5 A Phase I/II Study to Investigate Subconjunctival Sirolimus for the Treatment of Active Autoimmune Non-Necrotizing Anterior Scleritis Completed NCT01517074 Phase 1, Phase 2 Sirolimus
6 An Open Label, Multi-centered, Randomized Phase 2 Study to Evaluate the Safety, Tolerability and Bioactivity of Subcutaneous ACTH GeL in PAtients With Scleritis: The ATLAS Study Recruiting NCT03465111 Phase 2 ACTH (adrenocorticotropic hormone) gel
7 Tofacitinib for the Treatment of Inflammatory Eye Disease Active, not recruiting NCT03580343 Phase 2 tofacitinib
8 Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study Completed NCT01059955 Phase 1 Dexamethasone Phosphate Ophthalmic Solution (EGP-437);Dexamethasone phosphate ophthalmic solution
9 Pilot Study of the Evaluation of Infliximab in the Treatment of Non-Infectious Scleritis Completed NCT00075075 Phase 1 Infliximab
10 An Exploratory, Double Blind, Placebo-controlled, Randomized, Single-dose, Cross-over, Proof of Mechanism Study of Orally Administered PSI-697 in Patients With Scleritis Terminated NCT00367692 Phase 1 PSI-697
11 Observational Study of Visual Outcomes in Retinal Disease Unknown status NCT01613963 Immunosuppressive Agents
12 Optical Coherence Tomography in the Diagnosis of Scleritis and Episcleritis Completed NCT01958567
13 Autologous Perichondrium Transplantation for Replacement of Stem Cells and Their Niche in the Treatment of Necrotizing Scleritis Completed NCT02864823
14 Laboratory of Immunology/National Eye Institute Repository Completed NCT00539370
15 LSFG-SKIN, Laser Speckle Flowgraphy Completed NCT03660618
16 Prevalence of Ocular Manifestations in Inflammatory Rheumatic Diseases Active, not recruiting NCT03753893

Search NIH Clinical Center for Scleritis

Inferred drug relations via UMLS 71 / NDF-RT 51 :


medrysone

Cochrane evidence based reviews: scleritis

Genetic Tests for Scleritis

Anatomical Context for Scleritis

MalaCards organs/tissues related to Scleritis:

40
Eye, Skin, Neutrophil, Thyroid, Breast, Bone Marrow, Bone

Publications for Scleritis

Articles related to Scleritis:

(show top 50) (show all 1731)
# Title Authors PMID Year
1
Umbilical amnion and amniotic membrane transplantation for infectious scleritis and scleral melt: A case series. 61
33553804 2021
2
Recurrences of Scleritis after Ocular Surgery. 61
33545011 2021
3
Idiopathic nodular anterior scleritis. Biomicroscopic and tomographic findings. 61
33579527 2021
4
Nodular syphilitic scleritis: a rare and forgotten entity. 61
33599170 2021
5
Pyogenic granuloma after cosmetic eye whitening. 61
33158667 2021
6
Prognosis of Ocular Tuberculosis Following Long-Term Antitubercular Therapy. 61
33524301 2021
7
Prevalence and causes of clinically detectable uveitic serous retinal detachment. 61
33530714 2021
8
Atypical Noninfectious Surgically Induced Necrotizing Scleritis in a Child. 61
33544632 2021
9
Inflammatory rheumatic diseases in patients with ochronotic arthropathy. 61
33427541 2021
10
Ocular Manifestations in Rheumatoid Arthritis, Connective Tissue Disease, and Vasculitis: A Systematic Review and Metaanalysis. 61
32358156 2021
11
Scleritis and Aortitis in Early Rheumatoid Arthritis. 61
33492029 2021
12
Intravitreal dexamethasone implant - a new treatment for idiopathic posterior scleritis: A case report. 61
33521111 2021
13
Health system wide "big data" analysis of rheumatologic conditions and scleritis. 61
33407267 2021
14
Nodular anterior scleritis associated with Berger's disease. 61
33470345 2021
15
[Necrotizing scleritis after acanthamoeba keratitis]. 61
32162088 2021
16
Granulomatosis With Polyangiitis: Remissions in a Thiopurine Fast Metabolizer Over 20 Years. 61
33585105 2021
17
Recalcitrant infective scleritis masquerading an autoimmune necrotising scleritis: a primary presentation of biopsy-proven granulomatosis with polyangiitis. 61
33472807 2021
18
Optical Coherence Tomography Findings in Nodular Anterior Scleritis due to Post-Streptococcal Syndrome. 61
33520137 2021
19
Vedolizumab and Extraintestinal Manifestations in Inflammatory Bowel Disease. 61
33400241 2021
20
Membranous Nephropathy with Proteinase 3-ANCA-associated Vasculitis Successfully Treated with Rituximab. 61
32830174 2021
21
Ocular Manifestations of Inflammatory Bowel Disease. 61
33501989 2021
22
IgG4-related disease presenting as recurrent scleritis combined with optic neuropathy. 61
33402162 2021
23
Fibromyalgia syndrome and the eye-A review. 61
32512032 2021
24
Vascular abnormalities in uveitis. 61
33412171 2021
25
Tuberculous Scleritis and Multidrug Resistance. 61
33416427 2021
26
Clinical characteristics and efficacy of methotrexate in Japanese patients with noninfectious scleritis. 61
33107015 2021
27
Posterior scleritis as a rare manifestation of Behçet's disease. 61
33160729 2021
28
Infliximab for management of severe refractory posterior scleritis in a 9-year-old boy. 61
33358990 2020
29
Necrotising fungal scleritis with full-thickness scleral melt and circumferential progression: a novel debridement approach. 61
33372014 2020
30
Drug-induced ocular inflammation. 61
33332330 2020
31
Bilateral Acanthamoeba Panophthalmitis: A rare and unique case. 61
33117918 2020
32
Ocular Involvement in Sjogren's Syndrome: Risk Factors for Severe Visual Impairment and Vision-Threatening Corneal Complications. 61
33385368 2020
33
Necrotizing scleritis as the initial presentation of granulomatosis with polyangiitis. 61
33372890 2020
34
Posterior Scleritis as a Paraneoplastic Syndrome in Colon Cancer: A Case Report 61
33389939 2020
35
The haplotypes of various TNF related genes associated with scleritis in Chinese Han. 61
33287909 2020
36
Accelerated corneal endothelial cell loss in two patients with granulomatosis with polyangiitis following phacoemulsification. 61
33287743 2020
37
Clinical course of von Szily reaction: Case report and comprehensive review of the literature. 61
33015408 2020
38
Current Approach for the Diagnosis and Management of Noninfective Scleritis. 61
33290287 2020
39
[Ocular manifestations of Crohn's disease]. 61
32950292 2020
40
Reactive AA Amyloidosis in the setting of infective endocarditis manifesting as bilateral orbitopathy and choroidopathy. 61
33394958 2020
41
Necrotizing scleritis following uncomplicated strabismus surgery. 61
33120690 2020
42
The Existence of Periodontal Disease and Subsequent Ocular Diseases: A Population-Based Cohort Study. 61
33218003 2020
43
Eye pain in the white and quiet eye. 61
33009080 2020
44
Eye on the Enigmatic Link: Dysbiotic Oral Pathogens in Ocular Diseases; The Flip Side. 61
33179994 2020
45
Effectiveness of TNF-α blockade in the treatment of refractory non-infectious scleritis: a multicentre study. 61
32301435 2020
46
Necrotizing Scleritis. 61
33211932 2020
47
Recurrent posterior scleritis with secondary choroidal osteoma in a child. 61
33120660 2020
48
Bilateral posterior scleritis as a form of presentation of giant cell arteritis. 61
33171310 2020
49
Topical Erythropoietin as a Novel Treatment for Necrotizing Scleritis After Pterygium Surgery: A Pilot Study. 61
33156082 2020
50
Segmental Choroidal Vasculitis in Nodular Posterior Scleritis Associated with Polyarteritis Nodosa. 61
32826795 2020

Variations for Scleritis

Expression for Scleritis

Search GEO for disease gene expression data for Scleritis.

Pathways for Scleritis

Pathways related to Scleritis according to GeneCards Suite gene sharing:

(show all 43)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.81 TNF PTPN22 PRTN3 MPO MMP9 ITGB2
2
Show member pathways
13.36 TNF ITGB2 IL5 IL4 IL22 CCR6
3
Show member pathways
13.33 TNF PRTN3 MMP9 ITGB2 IL5 IL4
4
Show member pathways
13.27 TNF PTPN22 IL5 IL4 IL22 CCR6
5
Show member pathways
12.84 TNF ITGB2 IL5 IL4 IL22 IFNG
6
Show member pathways
12.59 TNF IL5 IL4 IFNG CTLA4
7
Show member pathways
12.58 TNF IL5 IL4 IL22 IFNG
8
Show member pathways
12.46 TNF ITGB2 IL4 IFNG
9
Show member pathways
12.37 IL5 IL4 IL22 IFNG
10
Show member pathways
12.29 TNF MMP9 IL5 IL4 IFNG CCL2
11
Show member pathways
12.27 TNF MPO IL4 IFNG CRP CCL2
12 12.27 TNF PTPN22 MPO ITGB2 IL4 IFNG
13
Show member pathways
12.24 TNF ITGB2 IL4 IFNG
14 12.12 TNF SELE MMP9 IFNG CCL2
15 12.02 TNF MMP9 IL4 IFNG CCL2
16 12 TNF MPO IL5 IL4 IFNG
17 11.98 TNF SELE MMP9 CCL2
18 11.98 TNF MMP9 ITGB2 IL4 CCL2
19 11.87 TNF ITGB2 IFNG
20 11.86 TNF SELE CCL2
21 11.86 TNF IL5 IL4
22 11.86 TNF ITGB2 IFNG CTLA4 CCL2
23 11.83 SELE IL5 IL4 IFNG
24
Show member pathways
11.81 IL4 IL22 IFNG
25
Show member pathways
11.71 TNF IL5 IL4 IFNG CTLA4
26
Show member pathways
11.7 TNF SELE MMP9 IFNG
27 11.6 TNF MMP9 IL5 IL4 CCL2
28 11.57 TNF ITGB2 IFNG CCL2
29 11.57 TNF MPO MMP9 ITGB2
30 11.53 TNF IL4 CCL2
31 11.5 IL5 IL4 IFNG
32 11.42 TNF SELE ITGB2 IFNG CCL2
33 11.39 TNF SELE IFNG
34 11.34 TNF IL5 IL4 IL22 IFNG CCR6
35 11.33 IL5 IL4 IFNG
36 11.27 TNF IL5 IL4 IFNG
37 11.21 IL5 IL4 IFNG
38 11.19 MMP9 IFNG CCL2
39 11.16 TNF IL5 IL4 IL22 IFNG
40 11.01 TNF ITGB2 IL5 IL4 IL22 CCL2
41 10.99 TNF MPO CCL2
42 10.92 TNF ITGB2 IL5 IL4 CTLA4 CCR6
43 10.76 IL5 IL4

GO Terms for Scleritis

Cellular components related to Scleritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 TNF PRTN3 MPO MMP9 IL5 IL4
2 membrane raft GO:0045121 9.46 TNF SELE PRTN3 ITGB2
3 extracellular space GO:0005615 9.36 TNF SELE PRTN3 MPO MMP9 IL5

Biological processes related to Scleritis according to GeneCards Suite gene sharing:

(show all 24)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.97 TNF PTPN22 IL4 IFNG CRP
2 leukocyte migration GO:0050900 9.85 TNF SELE MMP9 ITGB2
3 immune response GO:0006955 9.8 TNF IL5 IL4 IFNG CTLA4 CCR6
4 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.76 TNF IL4 IFNG
5 positive regulation of nitric oxide biosynthetic process GO:0045429 9.67 TNF ITGB2 IFNG
6 lipopolysaccharide-mediated signaling pathway GO:0031663 9.63 TNF PTPN22 CCL2
7 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.62 TNF ITGB2
8 humoral immune response GO:0006959 9.62 TNF IFNG CCR6 CCL2
9 negative regulation of amyloid-beta clearance GO:1900222 9.61 TNF IFNG
10 positive regulation of podosome assembly GO:0071803 9.61 TNF IL5
11 positive regulation of MHC class II biosynthetic process GO:0045348 9.6 IL4 IFNG
12 negative regulation of lipid storage GO:0010888 9.59 TNF CRP
13 positive regulation of NMDA glutamate receptor activity GO:1904783 9.57 IFNG CCL2
14 positive regulation of mononuclear cell migration GO:0071677 9.56 TNF IL4
15 positive regulation of cellular respiration GO:1901857 9.54 IL4 IFNG
16 leukocyte migration involved in inflammatory response GO:0002523 9.54 SELE ITGB2 CCR6
17 neuroinflammatory response GO:0150076 9.52 IL4 IFNG
18 cellular extravasation GO:0045123 9.51 TNF ITGB2
19 inflammatory response GO:0006954 9.5 TNF SELE ITGB2 IL5 IL22 CRP
20 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.48 TNF IFNG
21 microglial cell activation GO:0001774 9.46 TNF ITGB2 IL4 IFNG
22 positive regulation of vitamin D biosynthetic process GO:0060557 9.43 TNF IFNG
23 positive regulation of nitrogen compound metabolic process GO:0051173 9.4 TNF IFNG
24 cytokine-mediated signaling pathway GO:0019221 9.28 TNF PRTN3 MMP9 ITGB2 IL5 IL4

Molecular functions related to Scleritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.86 TNF SELE PTPN22 PRTN3 MPO MMP9
2 cytokine activity GO:0005125 9.1 TNF IL5 IL4 IL22 IFNG CCL2

Sources for Scleritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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