MCID: SCL015
MIFTS: 50

Scleritis

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Scleritis

MalaCards integrated aliases for Scleritis:

Name: Scleritis 12 53 44 15 73

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:13452
ICD10 33 H15.0 H15.00
ICD9CM 35 379.00
MeSH 44 D015423
NCIt 50 C119046
UMLS 73 C0036416

Summaries for Scleritis

MalaCards based summary : Scleritis is related to cellulitis and pyoderma gangrenosum. An important gene associated with Scleritis is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Adrenocorticotropic Hormone and beta-endorphin have been mentioned in the context of this disorder. Affiliated tissues include eye, neutrophil and thyroid, and related phenotypes are hematopoietic system and immune system

Wikipedia : 76 Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as... more...

Related Diseases for Scleritis

Diseases in the Scleritis family:

Posterior Scleritis Anterior Scleritis

Diseases related to Scleritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 310)
# Related Disease Score Top Affiliating Genes
1 cellulitis 30.5 IL5 TNF
2 pyoderma gangrenosum 30.2 ITGB2 TNF
3 pyoderma 30.1 ITGB2 TNF
4 chronic conjunctivitis 29.9 IL4 IL5
5 uveitis 29.7 CCL2 IL4 TNF
6 allergic conjunctivitis 29.6 IL4 IL5
7 brucellosis 29.6 IL4 TNF
8 wegener granulomatosis 29.5 ITGB2 SELE TNF
9 arthritis 29.5 CCL2 MMP9 TNF
10 stromal keratitis 29.4 CCL2 TNF
11 autoimmune disease 29.4 IL4 IL5 TNF
12 vasculitis 29.3 CCL2 SELE TNF
13 takayasu arteritis 29.3 MMP9 SELE TNF
14 pneumonia 29.1 CCL2 IL5 TNF
15 conjunctivitis 29.1 IL4 IL5
16 neuritis 28.6 CCL2 IL4 TNF
17 periodontitis 27.8 CCL2 IL4 MMP9 TNF
18 vascular disease 27.8 CCL2 MMP9 SELE TNF
19 systemic lupus erythematosus 27.6 CCL2 IL4 SELE TNF
20 multiple sclerosis 27.1 CCL2 IL4 IL5 MMP9 TNF
21 psoriasis 27.1 CCL2 IL22 IL4 SELE TNF
22 rheumatoid arthritis 26.7 CCL2 IL4 ITGB2 MMP9 SELE TNF
23 inflammatory bowel disease 26.3 CCL2 IL22 IL4 IL5 SELE TNF
24 posterior scleritis 12.1
25 anterior scleritis 12.1
26 brawny scleritis 12.1
27 scleroperikeratitis 11.1
28 angioimmunoblastic lymphadenopathy with dysproteinemia 10.7 IL5 TNF
29 cardiac sarcoidosis 10.7 IL5 TNF
30 autoimmune inner ear disease 10.6 MMP9 TNF
31 diverticulitis 10.6 MMP9 TNF
32 transverse myelitis 10.6 MMP9 TNF
33 tropical endomyocardial fibrosis 10.5 IL4 TNF
34 tungiasis 10.5 IL4 TNF
35 endomyocardial fibrosis 10.5 IL4 TNF
36 critical limb ischemia 10.5 SELE TNF
37 chronic meningitis 10.5 IL5 MMP9
38 churg-strauss syndrome 10.5 IL5 TNF
39 rosacea 10.5 MMP9 TNF
40 cheilitis 10.5 MMP9 TNF
41 retinitis pigmentosa 60 10.5 SELE TNF
42 actinic prurigo 10.5 SELE TNF
43 microscopic colitis 10.5 IL4 TNF
44 rheumatoid vasculitis 10.5 SELE TNF
45 primary systemic mycosis 10.5 IL4 TNF
46 poliomyelitis 10.5 IL4 TNF
47 orofacial granulomatosis 10.5 IL4 TNF
48 coccidiosis 10.5 IL4 TNF
49 eales disease 10.5 IL4 TNF
50 endometritis 10.5 SELE TNF

Comorbidity relations with Scleritis via Phenotypic Disease Network (PDN):


Rheumatoid Arthritis

Graphical network of the top 20 diseases related to Scleritis:



Diseases related to Scleritis

Symptoms & Phenotypes for Scleritis

MGI Mouse Phenotypes related to Scleritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.8 SELE TNF IL4 IL5 ITGB2 MMP9
2 immune system MP:0005387 9.8 TNF CCL2 IL4 IL5 ITGB2 MMP9
3 integument MP:0010771 9.55 SELE TNF IL4 ITGB2 MMP9
4 respiratory system MP:0005388 9.35 TNF IL4 IL5 MMP9 SELE
5 vision/eye MP:0005391 9.02 SELE TNF IL4 ITGB2 MMP9

Drugs & Therapeutics for Scleritis

Drugs for Scleritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 68)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Adrenocorticotropic Hormone Phase 4
2 beta-endorphin Phase 4
3 Hormone Antagonists Phase 4,Phase 3,Phase 1
4 Hormones Phase 4,Phase 3,Phase 1
5 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 1
6 Melanocyte-Stimulating Hormones Phase 4
7
Infliximab Approved Phase 3,Phase 1 170277-31-3
8
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
9
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
10
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
11 Antirheumatic Agents Phase 3,Phase 1,Phase 2
12 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
13 Anti-Inflammatory Agents Phase 3,Phase 1,Not Applicable
14 Antineoplastic Agents, Hormonal Phase 3,Phase 1
15 Dermatologic Agents Phase 3,Phase 1
16 Gastrointestinal Agents Phase 3,Phase 1
17 glucocorticoids Phase 3,Phase 1
18 Alkylating Agents Phase 3
19 Antineoplastic Agents, Alkylating Phase 3
20
Ephedrine Approved Phase 1, Phase 2 299-42-3 9294
21
Pseudoephedrine Approved Phase 1, Phase 2 90-82-4 7028
22
rituximab Approved Phase 1, Phase 2 174722-31-7 10201696
23
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177
24
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
25
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 5284616 6436030 46835353
26 Autonomic Agents Phase 1, Phase 2
27 Nasal Decongestants Phase 1, Phase 2
28 Ophthalmic Solutions Phase 1, Phase 2
29 Peripheral Nervous System Agents Phase 1, Phase 2
30 Pharmaceutical Solutions Phase 1, Phase 2
31 Respiratory System Agents Phase 1, Phase 2
32 Tetrahydrozoline Phase 1, Phase 2
33 Vasoconstrictor Agents Phase 1, Phase 2
34 Anti-Bacterial Agents Phase 1, Phase 2
35 Antibiotics, Antitubercular Phase 1, Phase 2
36 Anti-Infective Agents Phase 1, Phase 2
37 Antifungal Agents Phase 1, Phase 2
38 Antibodies Phase 1, Phase 2
39 Antibodies, Monoclonal Phase 1, Phase 2
40 Immunoglobulins Phase 1, Phase 2
41
Dexamethasone Approved, Investigational, Vet_approved Phase 1 50-02-2 5743
42 Antiemetics Phase 1
43 BB 1101 Phase 1
44 Dexamethasone 21-phosphate Phase 1
45 Dexamethasone acetate Phase 1 1177-87-3
46 HIV Protease Inhibitors Phase 1
47
protease inhibitors Phase 1
48
Adalimumab Approved 331731-18-1 16219006
49
Azathioprine Approved 446-86-6 2265
50
Etanercept Approved, Investigational 185243-69-0

Interventional clinical trials:

(show all 26)
# Name Status NCT ID Phase Drugs
1 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4 H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
2 Cyclophosphamide vs. Infliximab for Refractory Idiopathic Scleritis (CIRIS) Not yet recruiting NCT03088293 Phase 3 Infliximab;Cyclophosphamide
3 Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion. Unknown status NCT02300818 Phase 1, Phase 2 Seawater eyedrops
4 Gevokizumab for Active Scleritis Completed NCT01835132 Phase 1, Phase 2
5 Sirolimus Injections for Autoimmune Scleritis Completed NCT01517074 Phase 1, Phase 2 Sirolimus
6 Rituximab in the Treatment of Scleritis and Non-Infectious Orbital Inflammation Completed NCT00415506 Phase 1, Phase 2 Rituximab
7 Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma Active, not recruiting NCT01740297 Phase 1, Phase 2 Talimogene laherparepvec;Ipilimumab
8 A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis Not yet recruiting NCT03465111 Phase 2 ACTH (adrenocorticotropic hormone) gel
9 Tofacitinib for Inflammatory Eye Disease Not yet recruiting NCT03580343 Phase 2 tofacitinib
10 Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study Completed NCT01059955 Phase 1 Dexamethasone Phosphate Ophthalmic Solution (EGP-437);Dexamethasone phosphate ophthalmic solution
11 Infliximab to Treat Non-Infectious Scleritis Completed NCT00075075 Phase 1 Infliximab
12 Study Evaluating PSI-697 in Patients With Scleritis Terminated NCT00367692 Phase 1 PSI-697
13 Causes of Visual Loss in Retinal Disease Unknown status NCT01613963 Immunosuppressive Agents
14 Optical Coherence Tomography in the Diagnosis of Scleritis and Episcleritis Completed NCT01958567 Not Applicable
15 Perichondrium Autograft in Refractory Necrotizing Scleritis Completed NCT02864823 Not Applicable
16 Human Samples and Data Repository Completed NCT00539370
17 Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Completed NCT00116090
18 Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis Completed NCT02843438 Not Applicable Anti-toxoplasmosis treatment;Anti-inflammatory treatments
19 Influencing Factors in Uveitis Completed NCT00827086
20 Comparison Between Sutureless and Glue Free Versus Sutured Limbal Conjunctival Autograft in Primary Pterygium Surgery Completed NCT02009072 Not Applicable
21 A Non-Interventional Study in Rheumatoid Arthritis Patients Treated With Tocilizumab (RoActemra/Actemra) Completed NCT01613378
22 Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Completed NCT01579006 Tocilizumab
23 Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome Recruiting NCT02715323
24 Uveitis/Intraocular Inflammatory Disease Biobank (iBank) Recruiting NCT02656381
25 Immune Responses to Antigens in Non-infectious Eye Inflammatory Diseases Enrolling by invitation NCT00357071
26 A Comparison Between Surgical Techniques for Securing Conjunctival Autografting in Primary Pterygium Surgery Not yet recruiting NCT03301974 Not Applicable

Search NIH Clinical Center for Scleritis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: scleritis

Genetic Tests for Scleritis

Anatomical Context for Scleritis

MalaCards organs/tissues related to Scleritis:

41
Eye, Neutrophil, Thyroid, Bone, T Cells, Testes, Endothelial

Publications for Scleritis

Articles related to Scleritis:

(show top 50) (show all 661)
# Title Authors Year
1
Posterior scleritis follow-up by Swept-Source optical coherence tomography. ( 29169639 )
2018
2
Pulmonary nodules and nodular scleritis in a teenager with superficial granulomatous pyoderma gangrenosum. ( 29243307 )
2018
3
Nocardial scleritis: A case report and a suggested algorithm for disease management based on a literature review. ( 29780901 )
2018
4
Cyclophosphamide or Rituximab Treatment of Scleritis and Uveitis for Patients with Granulomatosis with Polyangiitis. ( 29635229 )
2018
5
Scleral Patch Graft With a Suture Reinforcement Technique in Surgical Management of Necrotizing Scleritis With Ectasia. ( 29664747 )
2018
6
Infectious Scleritis: What the ID Clinician Should Know. ( 29977974 )
2018
7
Necrotising scleritis, keratitis and uveitis in primary antiphospholipid syndrome. ( 29764818 )
2018
8
Combined Tenonplasty and Scleral Graft for Refractory <i>Pseudomonas</i> Scleritis Following Pterygium Removal with Mitomycin C Application. ( 29719651 )
2018
9
Iontophoretic delivery of dexamethasone phosphate for non-infectious, non-necrotising anterior scleritis, dose-finding clinical trial. ( 29666122 )
2018
10
Clinical Profile of Scleritis in Children. ( 29370565 )
2018
11
A case of scleritis associated rheumatoid arthritis accompanying an intraocular elevated lesion. ( 29843653 )
2018
12
Scedosporium apiospermum infectious scleritis following posterior subtenon triamcinolone acetonide injection: a case report and literature review. ( 29433463 )
2018
13
Atypical posterior scleritis mimicking choroidal melanoma. ( 29738013 )
2018
14
Limbal Stem Cell Deficiency Secondary to Diffuse Non-necrotizing Anterior Scleritis: A Clinicopathological Report. ( 29794824 )
2018
15
Clinical Features of Scleritis Across the Asia-Pacific Region. ( 29953309 )
2018
16
Combination nivolumab- and cabiralizumab-associated acute bilateral anterior and posterior scleritis and anterior uveitis. ( 29511745 )
2018
17
Clinical characteristics and ocular complications of patients with scleritis in Japanese. ( 29796754 )
2018
18
Association of Low Vitamin D Levels with Noninfectious Uveitis and Scleritis. ( 29474126 )
2018
19
SjAPgren's Disease Associated with Severe Retinal Vasculitis and/or Necrotizing Scleritis: Two Cases. ( 29452446 )
2018
20
Scleritis ( 29763119 )
2018
21
Successful management of bee sting induced <i>Aspergillus fumigatus</i> endophthalmitis and scleritis. ( 29480270 )
2018
22
Paradoxical Nodular Scleritis during Tocilizumab Therapy: A Case Report. ( 29093079 )
2017
23
Scleritis and Takayasu's disease - rare combined presentation. ( 29634707 )
2017
24
Necrobiotic xanthogranuloma scleritis in a case of granulomatosis with polyangiitis (Wegener's granulomatosis). ( 29042820 )
2017
25
Rituximab Induction and Maintenance Treatment in Patients with Scleritis and Granulomatosis with Polyangiitis (Wegener's). ( 28628344 )
2017
26
Successful treatment with tocilizumab for refractory scleritis associated with relapsing polychondritis. ( 28120637 )
2017
27
Hypertrophic Pachymeningitis Accompanying Scleritis. ( 28794383 )
2017
28
IgG4-related disease presenting as posterior scleritis and vitritis, progressing to multifocal orbital involvement. ( 28438752 )
2017
29
Conjunctival Necrosis Masquerading as Necrotizing Scleritis. ( 28910555 )
2017
30
Ocular metastasis from breast carcinoma simulating anterior scleritis: a case report. ( 28844204 )
2017
31
Interventions and Outcomes in Patients with Infectious Pseudomonas scleritis: A 10-Year Perspective. ( 29040032 )
2017
32
IgG4-related disease as an emerging cause of scleritis. ( 28229544 )
2017
33
Anakinra in the Treatment of Patients with Refractory Scleritis: A Pilot Study. ( 28537473 )
2017
34
Pseudomonas Scleritis following Pterygium Excision. ( 28924436 )
2017
35
Retinal and Choroidal Detachment in Antineutrophil Cytoplasmic Antibody-Associated Scleritis and Retinal Vasculitis Mimicking Choroidal Tumor. ( 28489623 )
2017
36
Ocular Pharmacology for Scleritis: Review of Treatment and a Practical Perspective. ( 28355124 )
2017
37
Anterior scleritis following intravitreal injections in a patient with rheumatoid arthritis: A case report. ( 29382031 )
2017
38
Management of Uveitis and Scleritis in Necrobiotic Xanthogranuloma. ( 28394239 )
2017
39
Indocyanine green angiography in anterior scleritis. ( 28886929 )
2017
40
Sweet Syndrome Associated with Bilateral Nodular Scleritis. ( 29282197 )
2017
41
Posterior Scleritis with Choroidal Effusion Secondary to Herpes Zoster Ophthalmicus. ( 28981391 )
2017
42
Endophthalmitis associated with Purpureocillium lilacinum during infliximab treatment for surgically induced necrotizing scleritis, successfully treated with 27-gauge vitrectomy. ( 28429128 )
2017
43
Occult Fungal Scleritis. ( 28275602 )
2017
44
An OCT Study of Anterior Nodular Episcleritis and Scleritis. ( 28348907 )
2017
45
Three atypical manifestations of granulomatosis with polyangiitis: lateral medullary syndrome, anterior cheek mass and melting scleritis of eye. ( 28769139 )
2017
46
Severe Idiopathic Posterior Scleritis in a Patient with HIV. ( 28147399 )
2017
47
Scleritis Associated with SAPHO Syndrome: A Case Report. ( 28060551 )
2017
48
Bilateral Posterior Scleritis Associated with Giant Cell Arteritis: A Case Report. ( 28914559 )
2017
49
When an Easy Thing Goes Wrong: Foreign Body Induced Granuloma-Associated Scleritis Following Pterygium Surgery. ( 28512421 )
2017
50
Anterior Scleritis Associated with Pemphigus Vulgaris. ( 29095065 )
2017

Variations for Scleritis

Expression for Scleritis

Search GEO for disease gene expression data for Scleritis.

Pathways for Scleritis

Pathways related to Scleritis according to GeneCards Suite gene sharing:

(show all 45)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.79 CCL2 IL22 IL4 IL5 ITGB2 MMP9
2
Show member pathways
13.63 CCL2 IL22 IL4 IL5 ITGB2 TNF
3
Show member pathways
13.3 CCL2 IL22 IL4 IL5 ITGB2 TNF
4
Show member pathways
13.18 CCL2 IL22 IL4 IL5 ITGB2 TNF
5
Show member pathways
13.11 CCL2 IL22 IL4 IL5 TNF
6
Show member pathways
13.06 CCL2 IL22 IL4 IL5 ITGB2 MMP9
7
Show member pathways
12.73 CCL2 MMP9 SELE TNF
8
Show member pathways
12.69 IL22 IL4 IL5 ITGB2 TNF
9
Show member pathways
12.49 IL22 IL4 IL5 TNF
10 12.42 CCL2 IL4 ITGB2 TNF
11
Show member pathways
12.34 IL4 ITGB2 TNF
12
Show member pathways
12.29 IL22 IL4 IL5 TNF
13
Show member pathways
12.27 IL4 IL5 TNF
14
Show member pathways
12.18 CCL2 IL4 TNF
15
Show member pathways
12.11 IL4 ITGB2 TNF
16
Show member pathways
12.05 CCL2 IL4 IL5 MMP9 TNF
17
Show member pathways
11.95 CCL2 IL22 IL4 IL5
18 11.92 CCL2 MMP9 SELE TNF
19 11.88 IL4 IL5 TNF
20 11.84 CCL2 IL4 MMP9 TNF
21 11.8 CCL2 SELE TNF
22 11.79 IL4 IL5 TNF
23 11.77 CCL2 MMP9 SELE TNF
24 11.75 CCL2 ITGB2 TNF
25 11.7 IL4 IL5 SELE
26
Show member pathways
11.66 IL4 IL5 TNF
27 11.57 IL22 IL4 IL5 TNF
28
Show member pathways
11.55 MMP9 SELE TNF
29 11.41 CCL2 IL4 ITGB2 MMP9 TNF
30 11.4 CCL2 IL4 TNF
31 11.38 ITGB2 MMP9 TNF
32 11.37 CCL2 ITGB2 TNF
33 11.36 IL4 IL5
34 11.28 MMP9 SELE
35 11.25 CCL2 ITGB2 SELE TNF
36 11.23 SELE TNF
37 11.21 CCL2 MMP9
38 11.19 IL4 IL5
39 11.18 CCL2 MMP9
40 11.15 IL4 IL5 TNF
41 11.08 IL4 IL5
42 11.06 CCL2 MMP9
43 10.96 IL22 IL4 IL5 TNF
44 10.85 CCL2 TNF
45 10.82 CCL2 IL4 IL5 MMP9 TNF

GO Terms for Scleritis

Cellular components related to Scleritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 CCL2 IL22 IL4 IL5 MMP9 TNF
2 membrane raft GO:0045121 9.33 ITGB2 SELE TNF
3 extracellular space GO:0005615 9.17 CCL2 IL22 IL4 IL5 MMP9 SELE

Biological processes related to Scleritis according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.76 CCL2 IL4 IL5 TNF
2 MAPK cascade GO:0000165 9.73 CCL2 IL5 TNF
3 extracellular matrix organization GO:0030198 9.69 ITGB2 MMP9 TNF
4 leukocyte migration GO:0050900 9.62 ITGB2 MMP9 SELE TNF
5 protein kinase B signaling GO:0043491 9.58 CCL2 TNF
6 positive regulation of nitric oxide biosynthetic process GO:0045429 9.58 ITGB2 TNF
7 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.57 MMP9 TNF
8 lipopolysaccharide-mediated signaling pathway GO:0031663 9.55 CCL2 TNF
9 regulation of signaling receptor activity GO:0010469 9.55 CCL2 IL22 IL4 IL5 TNF
10 endodermal cell differentiation GO:0035987 9.54 ITGB2 MMP9
11 leukocyte cell-cell adhesion GO:0007159 9.52 ITGB2 SELE
12 positive regulation of T cell differentiation GO:0045582 9.49 IL22 IL4
13 leukocyte tethering or rolling GO:0050901 9.48 SELE TNF
14 positive regulation of podosome assembly GO:0071803 9.43 IL5 TNF
15 positive regulation of B cell proliferation GO:0030890 9.43 IL22 IL4 IL5
16 inflammatory response GO:0006954 9.43 CCL2 IL22 IL5 ITGB2 SELE TNF
17 leukocyte migration involved in inflammatory response GO:0002523 9.4 ITGB2 SELE
18 cellular extravasation GO:0045123 9.37 ITGB2 TNF
19 cytokine-mediated signaling pathway GO:0019221 9.17 CCL2 IL22 IL4 IL5 ITGB2 MMP9

Molecular functions related to Scleritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 CCL2 IL22 IL4 IL5 TNF

Sources for Scleritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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