IS2
MCID: SCL058
MIFTS: 12

Scoliosis, Isolated 2 (IS2)

Categories: Bone diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Scoliosis, Isolated 2

MalaCards integrated aliases for Scoliosis, Isolated 2:

Name: Scoliosis, Isolated 2 56
Scoliosis, Idiopathic 2 56 13
Scoliosis, Isolated, Susceptibility to, 2 56
Is2 56

Classifications:



External Ids:

OMIM 56 607354

Summaries for Scoliosis, Isolated 2

OMIM : 56 Idiopathic scoliosis is a structurally fixed lateral curvature of the spine with a rotatory component. There is at least a 10 degree curvature as demonstrated by upright spine roentgenograms by the Cobb method (Weinstein, 1994). For a discussion of genetic heterogeneity of isolated scoliosis, see 181800. (607354)

MalaCards based summary : Scoliosis, Isolated 2, also known as scoliosis, idiopathic 2, is related to scoliosis and severe acute respiratory syndrome. An important gene associated with Scoliosis, Isolated 2 is IS2 (Scoliosis, Idiopathic 2). Affiliated tissues include bone.

Related Diseases for Scoliosis, Isolated 2

Diseases in the Scoliosis, Isolated 1 family:

Scoliosis, Isolated 2 Scoliosis, Isolated 3
Scoliosis, Isolated 4 Scoliosis, Isolated 5

Diseases related to Scoliosis, Isolated 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 scoliosis 11.4
2 severe acute respiratory syndrome 10.3
3 irritable bowel syndrome 10.3
4 muscular dystrophy 10.3
5 limb-girdle muscular dystrophy 10.3
6 colorectal cancer 10.1
7 muscular dystrophy, limb-girdle, autosomal recessive 1 10.1
8 pertussis 10.1
9 allergic hypersensitivity disease 10.1
10 constipation 10.1

Graphical network of the top 20 diseases related to Scoliosis, Isolated 2:



Diseases related to Scoliosis, Isolated 2

Symptoms & Phenotypes for Scoliosis, Isolated 2

Clinical features from OMIM:

607354

Drugs & Therapeutics for Scoliosis, Isolated 2

Search Clinical Trials , NIH Clinical Center for Scoliosis, Isolated 2

Genetic Tests for Scoliosis, Isolated 2

Anatomical Context for Scoliosis, Isolated 2

MalaCards organs/tissues related to Scoliosis, Isolated 2:

40
Bone

Publications for Scoliosis, Isolated 2

Articles related to Scoliosis, Isolated 2:

# Title Authors PMID Year
1
Assignment of a locus for autosomal dominant idiopathic scoliosis (IS) to human chromosome 17p11. 56
12384783 2002

Variations for Scoliosis, Isolated 2

Expression for Scoliosis, Isolated 2

Search GEO for disease gene expression data for Scoliosis, Isolated 2.

Pathways for Scoliosis, Isolated 2

GO Terms for Scoliosis, Isolated 2

Sources for Scoliosis, Isolated 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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