IS2
MCID: SCL058
MIFTS: 12

Scoliosis, Isolated 2 (IS2)

Categories: Bone diseases, Rare diseases

Aliases & Classifications for Scoliosis, Isolated 2

MalaCards integrated aliases for Scoliosis, Isolated 2:

Name: Scoliosis, Isolated 2 58
Scoliosis, Idiopathic 2 58 13
Scoliosis, Isolated, Susceptibility to, 2 58
Is2 58

Classifications:



External Ids:

OMIM 58 607354

Summaries for Scoliosis, Isolated 2

OMIM : 58 Idiopathic scoliosis is a structurally fixed lateral curvature of the spine with a rotatory component. There is at least a 10 degree curvature as demonstrated by upright spine roentgenograms by the Cobb method (Weinstein, 1994). For a discussion of genetic heterogeneity of isolated scoliosis, see 181800. (607354)

MalaCards based summary : Scoliosis, Isolated 2, also known as scoliosis, idiopathic 2, is related to scoliosis and muscular dystrophy. An important gene associated with Scoliosis, Isolated 2 is IS2 (Scoliosis, Idiopathic 2). Affiliated tissues include bone.

Related Diseases for Scoliosis, Isolated 2

Diseases in the Scoliosis, Isolated 1 family:

Scoliosis, Isolated 2 Scoliosis, Isolated 3
Scoliosis, Isolated 4 Scoliosis, Isolated 5

Diseases related to Scoliosis, Isolated 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 scoliosis 11.3
2 muscular dystrophy 10.2
3 limb-girdle muscular dystrophy 10.2
4 colorectal cancer 10.1
5 muscular dystrophy, limb-girdle, autosomal recessive 1 10.1
6 constipation 10.1
7 irritable bowel syndrome 10.1

Graphical network of the top 20 diseases related to Scoliosis, Isolated 2:



Diseases related to Scoliosis, Isolated 2

Symptoms & Phenotypes for Scoliosis, Isolated 2

Clinical features from OMIM:

607354

Drugs & Therapeutics for Scoliosis, Isolated 2

Search Clinical Trials , NIH Clinical Center for Scoliosis, Isolated 2

Genetic Tests for Scoliosis, Isolated 2

Anatomical Context for Scoliosis, Isolated 2

MalaCards organs/tissues related to Scoliosis, Isolated 2:

42
Bone

Publications for Scoliosis, Isolated 2

Variations for Scoliosis, Isolated 2

Expression for Scoliosis, Isolated 2

Search GEO for disease gene expression data for Scoliosis, Isolated 2.

Pathways for Scoliosis, Isolated 2

GO Terms for Scoliosis, Isolated 2

Sources for Scoliosis, Isolated 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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