MCID: SCR017
MIFTS: 20

Scrotum Neoplasm

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Scrotum Neoplasm

MalaCards integrated aliases for Scrotum Neoplasm:

Name: Scrotum Neoplasm 12 15
Malignant Tumour of Scrotum 12
Malignant Scrotal Neoplasm 12
Malignant Tumor of Scrotum 12
Neoplasm of Scrotum 12
Scrotum Cancer 12
Scrotal Tumor 12
Scrotal Ca 12

Classifications:



External Ids:

Disease Ontology 12 DOID:518
ICD9CM 34 187.7
NCIt 50 C3560 C4380
SNOMED-CT 67 126905005 93999006
ICD10 32 C63.2
UMLS 71 C0153604 C0341790

Summaries for Scrotum Neoplasm

MalaCards based summary : Scrotum Neoplasm, also known as malignant tumour of scrotum, is related to scrotal carcinoma and mixed hepatoblastoma. An important gene associated with Scrotum Neoplasm is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways is Cell adhesion_Cadherin-mediated cell adhesion.

Related Diseases for Scrotum Neoplasm

Diseases related to Scrotum Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
# Related Disease Score Top Affiliating Genes
1 scrotal carcinoma 31.9 SPRR2D MIR30C2
2 mixed hepatoblastoma 10.2 SERPINA3 AFP
3 pancreas sarcoma 10.2 SERPINA3 AFP
4 testicular malignant germ cell cancer 10.2 SERPINA3 AFP
5 liver sarcoma 10.2 SERPINA3 AFP
6 cystadenoma 10.2 SERPINA3 AFP
7 pancreatic acinar cell adenocarcinoma 10.2 SERPINA3 AFP
8 testicular yolk sac tumor 10.2 SERPINA3 AFP
9 hepatoid adenocarcinoma 10.2 SERPINA3 AFP
10 cystic lymphangioma 10.2 SERPINA3 AFP
11 pancreatoblastoma 10.2 SERPINA3 AFP
12 pancreatic endocrine carcinoma 10.2 SERPINA3 AFP
13 opisthorchiasis 10.2 SERPINA3 AFP
14 plasma protein metabolism disease 10.2 SERPINA3 AFP
15 acinar cell carcinoma 10.2 SERPINA3 AFP
16 trophoblastic neoplasm 10.2 SERPINA3 AFP
17 reproductive organ benign neoplasm 10.2 SERPINA3 AFP
18 vein disease 10.2 SERPINA3 AFP
19 undifferentiated embryonal sarcoma of the liver 10.1 SERPINA3 MYOG
20 embryonal sarcoma 10.1 SERPINA3 MYOG
21 malignant mesenchymoma 10.1 SERPINA3 MYOG
22 pineal region teratoma 10.1 MYOG AFP
23 heart cancer 10.1 SERPINA3 MYOG
24 pediatric fibrosarcoma 10.1 SERPINA3 MYOG
25 bladder sarcoma 10.1 SERPINA3 MYOG
26 cardiovascular organ benign neoplasm 10.1 SERPINA3 AFP
27 gas gangrene 10.1 SERPINA3 MYOG
28 fibroma 10.1 SERPINA3 ACTC1
29 testicular disease 10.1 SERPINA3 AFP
30 mesenchymal cell neoplasm 10.1 SERPINA3 MYOG
31 fibrous histiocytoma 10.1 SERPINA3 ACTC1
32 intravascular papillary endothelial hyperplasia 10.1 SERPINA3 ACTC1
33 childhood malignant schwannoma 10.1 NFIC MYOG
34 synovium cancer 10.1 SERPINA3 MYOG
35 syringocystadenoma papilliferum 10.1 SERPINA3 ACTC1
36 alpha-1-antitrypsin deficiency 10.1 SERPINA3 AFP
37 non-langerhans-cell histiocytosis 10.1 SERPINA3 ACTC1
38 well-differentiated liposarcoma 10.1 SERPINA3 MYOG
39 epithelioid leiomyosarcoma 10.1 SERPINA3 ACTC1
40 vascular cancer 10.1 SERPINA3 MYOG
41 lymphangioma 10.1 SERPINA3 ACTC1
42 skeletal muscle cancer 10.1 SERPINA3 MYOG
43 pleomorphic liposarcoma 10.1 SERPINA3 ACTC1
44 adenosarcoma 10.1 SERPINA3 ACTC1
45 muscle cancer 10.1 SERPINA3 MYOG
46 cutaneous fibrous histiocytoma 10.1 SERPINA3 ACTC1
47 myxofibrosarcoma 10.0 SERPINA3 MYOG
48 smooth muscle tumor 10.0 SERPINA3 ACTC1
49 tuberculous epididymitis 10.0
50 benign giant cell tumor 10.0 SERPINA3 ACTC1

Graphical network of the top 20 diseases related to Scrotum Neoplasm:



Diseases related to Scrotum Neoplasm

Symptoms & Phenotypes for Scrotum Neoplasm

Drugs & Therapeutics for Scrotum Neoplasm

Search Clinical Trials , NIH Clinical Center for Scrotum Neoplasm

Genetic Tests for Scrotum Neoplasm

Anatomical Context for Scrotum Neoplasm

Publications for Scrotum Neoplasm

Articles related to Scrotum Neoplasm:

# Title Authors PMID Year
1
A brief history of cancer: age-old milestones underlying our current knowledge database. 61
25113657 2015
2
Socio-economic differences in incidence rates of cancers of the male genital organs in Finland, 1971-95. 61
12448008 2002

Variations for Scrotum Neoplasm

Expression for Scrotum Neoplasm

Search GEO for disease gene expression data for Scrotum Neoplasm.

Pathways for Scrotum Neoplasm

Pathways related to Scrotum Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.23 ACTG2 ACTC1

GO Terms for Scrotum Neoplasm

Cellular components related to Scrotum Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 SERPINA3 MIR30C2 AFP ACTG2 ACTC1
2 filopodium GO:0030175 9.26 ACTG2 ACTC1
3 dynactin complex GO:0005869 8.96 ACTG2 ACTC1
4 blood microparticle GO:0072562 8.8 SERPINA3 ACTG2 ACTC1

Biological processes related to Scrotum Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mesenchyme migration GO:0090131 8.62 ACTG2 ACTC1

Molecular functions related to Scrotum Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proximal promoter sequence-specific DNA binding GO:0000987 8.62 NFIC MYOG

Sources for Scrotum Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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