MCID: SBR007
MIFTS: 16

Seborrhea-Like Dermatitis with Psoriasiform Elements

Categories: Genetic diseases, Skin diseases, Rare diseases

Aliases & Classifications for Seborrhea-Like Dermatitis with Psoriasiform Elements

MalaCards integrated aliases for Seborrhea-Like Dermatitis with Psoriasiform Elements:

Name: Seborrhea-Like Dermatitis with Psoriasiform Elements 57 59 75 29 13 6 40
Seborrhea-Like Dermatitis with Psoriasiform Element 37
Sldp 75

Characteristics:

Orphanet epidemiological data:

59
seborrhea-like dermatitis with psoriasiform elements
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: Childhood;

HPO:

32
seborrhea-like dermatitis with psoriasiform elements:
Inheritance autosomal dominant inheritance


Classifications:

Orphanet: 59  
Rare skin diseases


External Ids:

OMIM 57 610227
Orphanet 59 ORPHA168606
UMLS via Orphanet 74 C1853258
MedGen 42 C1853258
KEGG 37 H00795

Summaries for Seborrhea-Like Dermatitis with Psoriasiform Elements

UniProtKB/Swiss-Prot : 75 Seborrhea-like dermatitis with psoriasiform elements: Characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders.

MalaCards based summary : Seborrhea-Like Dermatitis with Psoriasiform Elements, also known as seborrhea-like dermatitis with psoriasiform element, is related to dermatitis. An important gene associated with Seborrhea-Like Dermatitis with Psoriasiform Elements is ZNF750 (Zinc Finger Protein 750). Affiliated tissues include skin, and related phenotypes are hyperkeratosis and seborrheic dermatitis

Description from OMIM: 610227

Related Diseases for Seborrhea-Like Dermatitis with Psoriasiform Elements

Diseases related to Seborrhea-Like Dermatitis with Psoriasiform Elements via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 dermatitis 10.2

Symptoms & Phenotypes for Seborrhea-Like Dermatitis with Psoriasiform Elements

Clinical features from OMIM:

610227

Human phenotypes related to Seborrhea-Like Dermatitis with Psoriasiform Elements:

32
# Description HPO Frequency HPO Source Accession
1 hyperkeratosis 32 HP:0000962
2 seborrheic dermatitis 32 HP:0001051

Drugs & Therapeutics for Seborrhea-Like Dermatitis with Psoriasiform Elements

Search Clinical Trials , NIH Clinical Center for Seborrhea-Like Dermatitis with Psoriasiform Elements

Genetic Tests for Seborrhea-Like Dermatitis with Psoriasiform Elements

Genetic tests related to Seborrhea-Like Dermatitis with Psoriasiform Elements:

# Genetic test Affiliating Genes
1 Seborrhea-Like Dermatitis with Psoriasiform Elements 29 ZNF750

Anatomical Context for Seborrhea-Like Dermatitis with Psoriasiform Elements

MalaCards organs/tissues related to Seborrhea-Like Dermatitis with Psoriasiform Elements:

41
Skin

Publications for Seborrhea-Like Dermatitis with Psoriasiform Elements

Articles related to Seborrhea-Like Dermatitis with Psoriasiform Elements:

# Title Authors Year
1
Seborrhea-like dermatitis with psoriasiform elements caused by a mutation in ZNF750, encoding a putative C2H2 zinc finger protein. ( 16751772 )
2006

Variations for Seborrhea-Like Dermatitis with Psoriasiform Elements

ClinVar genetic disease variations for Seborrhea-Like Dermatitis with Psoriasiform Elements:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 ZNF750 ZNF750, 2-BP DUP, 56CC duplication Pathogenic

Expression for Seborrhea-Like Dermatitis with Psoriasiform Elements

Search GEO for disease gene expression data for Seborrhea-Like Dermatitis with Psoriasiform Elements.

Pathways for Seborrhea-Like Dermatitis with Psoriasiform Elements

GO Terms for Seborrhea-Like Dermatitis with Psoriasiform Elements

Sources for Seborrhea-Like Dermatitis with Psoriasiform Elements

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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