MCID: SCN068
MIFTS: 19

Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards integrated aliases for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

Name: Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease 58
Secondary Ild in Childhood and Adulthood Associated with a Connective Tissue Disease 58
Ctd-Ild 58

Classifications:

Orphanet: 58  
Rare respiratory diseases


External Ids:

Orphanet 58 ORPHA182104

Summaries for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards based summary : Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease, also known as secondary ild in childhood and adulthood associated with a connective tissue disease, is related to interstitial lung disease and connective tissue disease. The drugs Pirfenidone and Acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and skin.

Related Diseases for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 interstitial lung disease 10.7
2 connective tissue disease 10.7
3 lung disease 10.7
4 scleroderma, familial progressive 10.5
5 pulmonary fibrosis, idiopathic 10.3
6 rickets 10.3
7 pulmonary fibrosis 10.3
8 myopathy 10.3

Graphical network of the top 20 diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:



Diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Symptoms & Phenotypes for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Drugs & Therapeutics for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Drugs for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pirfenidone Approved, Investigational Phase 3 53179-13-8 40632
2
Acetylcysteine Approved, Investigational Phase 2, Phase 3 616-91-1 12035
3 Analgesics, Non-Narcotic Phase 3
4 Analgesics Phase 3
5 Anti-Inflammatory Agents Phase 3
6 Antirheumatic Agents Phase 3
7 Anti-Inflammatory Agents, Non-Steroidal Phase 3
8 Respiratory System Agents Phase 2, Phase 3
9 Anti-Infective Agents Phase 2, Phase 3
10 Antidotes Phase 2, Phase 3
11 Antioxidants Phase 2, Phase 3
12 Antiviral Agents Phase 2, Phase 3
13 Expectorants Phase 2, Phase 3
14 N-monoacetylcystine Phase 2, Phase 3
15 Protective Agents Phase 2, Phase 3
16
Midazolam Approved, Illicit 59467-70-8 4192
17
Lidocaine Approved, Vet_approved 137-58-6 3676
18 Anesthetics
19 Pharmaceutical Solutions
20 Calamus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized, Open-label Study to Evaluate the Efficacy and Safety of Pirfenidone in Patients With Severe and Critical Novel Coronavirus Infection Recruiting NCT04282902 Phase 3 pirfenidone
2 Clinical Trial of Oral Medication for CTD-ILD Treatment Terminated NCT01424033 Phase 2, Phase 3 N-Acetylcysteine
3 Study of the Etiology and Immunological Pathogenesis in Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF) Unknown status NCT02509364
4 Telemonitoring as a Tool for the Assessment of Treatment Effects of Connective Tissue Disease-associated Interstitial Lung Disease (TEL-CTD-ILD) Recruiting NCT04428957
5 The Clinical Course of Interstitial Pneumonia With Autoimmune Features: an Observational, Prospective Cohort Study Recruiting NCT03950583
6 Incidence, Clinical Characteristics and Evaluation of Prognostic and Diagnostic Markers of Interstitial Pneumonia With Autoimmune Features (IPAF) - a Multicenter Prospective Study Not yet recruiting NCT03870828

Search NIH Clinical Center for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Genetic Tests for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Anatomical Context for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards organs/tissues related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

40
Lung, Testes, Skin, T Cells, B Cells, Neutrophil

Publications for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Articles related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

(show top 50) (show all 153)
# Title Authors PMID Year
1
Circulating lung biomarkers in idiopathic lung fibrosis and interstitial lung diseases associated with connective tissue diseases: Where do we stand? 61
32089354 2020
2
Long-term clinical course and outcome of interstitial pneumonia with autoimmune features. 61
31387157 2020
3
Costs of Workplace Productivity Loss in Patients with Connective Tissue Disease Associated Interstitial Lung Disease. 61
32437249 2020
4
Mechanical ventilation for acute respiratory failure due to idiopathic pulmonary fibrosis versus connective tissue disease-associated interstitial lung disease: Effectiveness and risk factors for death. 61
32460444 2020
5
IPAF should receive early treatment for sharing similar clinical characteristics as CTD-ILD: a report from 273 Chinese patients. 61
32447599 2020
6
Comparative diagnostic efficacy of serum Krebs von den Lungen-6 and surfactant D for connective tissue disease-associated interstitial lung diseases: A meta-analysis. 61
32311947 2020
7
Bronchoalveolar Lavage Fluid Lymphocytosis in Chronic Hypersensitivity Pneumonitis: A Systematic Review and Meta-Analysis. 61
32265306 2020
8
[The clinical features and prognosis of interstitial lung disease patients with positive anti-neutrophil cytoplasmic antibody]. 61
32294819 2020
9
[Interstitial lung disease in rheumatic diseases - new therapeutic approaches]. 61
32236928 2020
10
Vitamin D levels are prognostic factors for connective tissue disease associated interstitial lung disease (CTD-ILD). 61
32167486 2020
11
Treatment of the Connective Tissue Disease-Related Interstitial Lung Diseases: A Narrative Review. 61
32138882 2020
12
Connective tissue disease-associated interstitial lung disease. 61
32044296 2020
13
Association of ADAM17 Expression Levels in Patients with Interstitial Lung Disease. 61
31469350 2020
14
Therapeutic Options for the Treatment of Interstitial Lung Disease Related to Connective Tissue Diseases. A Narrative Review. 61
32028635 2020
15
Comparative analysis of connective tissue disease-associated interstitial lung disease and interstitial pneumonia with autoimmune features. 61
31758424 2020
16
Impact of a systematic evaluation of connective tissue disease on diagnosis approach in patients with interstitial lung diseases. 61
31977850 2020
17
Study on the Red Blood Cell Distribution Width in Connective Tissue Disease Associated with Interstitial Lung Disease. 61
32047815 2020
18
The value of serum Krebs von den lungen-6 as a diagnostic marker in connective tissue disease associated with interstitial lung disease. 61
31915006 2020
19
High resolution computed tomography patterns in interstitial lung disease (ILD): prevalence and prognosis. 61
32159601 2020
20
Real-world experiences: Efficacy and tolerability of pirfenidone in clinical practice. 61
31999801 2020
21
Clinical significance of self-reported cough intensity and frequency in patients with interstitial lung disease: a cross-sectional study. 61
31842848 2019
22
Acute exacerbations of fibrosing interstitial lung disease associated with connective tissue diseases: a population-based study. 61
31727051 2019
23
Antinuclear antibodies in interstitial lung disease: Prevalence and clinical significance. 61
32173825 2019
24
Baseline characteristics and comorbidities in the CAnadian REgistry for Pulmonary Fibrosis. 61
31771541 2019
25
[Clinical value of myositis antibodies in patients with connective tissue disease-associated interstitial lung diseases]. 61
31594111 2019
26
Review: Serum biomarkers in idiopathic pulmonary fibrosis and systemic sclerosis associated interstitial lung disease - frontiers and horizons. 61
31153954 2019
27
Exploring the Ability of Electronic Nose Technology to Recognize Interstitial Lung Diseases (ILD) by Non-Invasive Breath Screening of Exhaled Volatile Compounds (VOC): A Pilot Study from the European IPF Registry (eurIPFreg) and Biobank. 61
31623141 2019
28
Long-term survival of lung transplantation for interstitial lung disease associated with connective tissue diseases: a study of 26 cases from a referral centre. 61
31694743 2019
29
[Expression and clinical significance of CCL18 in bronchoalveolar lavage fluid of connective tissue disease-associated interstitial lung disease]. 61
31607028 2019
30
Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 5. Connective Tissue Disease Associated Interstitial Lung Disease. 61
31172701 2019
31
Demographic and clinical predictors of progression and mortality in connective tissue disease-associated interstitial lung disease: a retrospective cohort study. 61
31672127 2019
32
[The diagnostic value of serum KL-6 in connective tissue disease associated interstitial lung disease]. 61
31694110 2019
33
Current and Emerging Drug Therapies for Connective Tissue Disease-Interstitial Lung Disease (CTD-ILD). 61
31399860 2019
34
Hyaluronic Acid-Decorated Liposomes as Innovative Targeted Delivery System for Lung Fibrotic Cells. 61
31509965 2019
35
Clinical features and outcome of acute exacerbation in connective tissue disease-associated interstitial lung disease: A single-center study from India. 61
31328423 2019
36
Feasibility of low-dose CT with spectral shaping and third-generation iterative reconstruction in evaluating interstitial lung diseases associated with connective tissue disease: an intra-individual comparison study. 61
30737567 2019
37
In vivo probe-based confocal laser endomicroscopy in chronic interstitial lung diseases: Specific descriptors and correlation with chest CT. 61
30811085 2019
38
Impact of an interstitial lung disease service in the diagnosis and management of interstitial lung disease in Singapore. 61
31317200 2019
39
Interstitial pneumonia with autoimmune features show better survival and less exacerbations compared to idiopathic pulmonary fibrosis. 61
31272428 2019
40
Rituximab in connective tissue disease-associated interstitial lung disease. 61
31016581 2019
41
Connective tissue disease-associated interstitial lung disease and outcomes after hospitalization: A cohort study. 61
31176795 2019
42
Comparison of clinical courses and mortality of connective tissue disease-associated interstitial pneumonias and chronic fibrosing idiopathic interstitial pneumonias. 61
30913371 2019
43
Lung Cancer development and mortality in interstitial lung disease with and without connective tissue diseases: a five-year Nationwide population-based study. 61
31182103 2019
44
Computed Tomography Honeycombing Identifies a Progressive Fibrotic Phenotype with Increased Mortality across Diverse Interstitial Lung Diseases. 61
30653927 2019
45
Telomere length and genetic variant associations with interstitial lung disease progression and survival. 61
30635297 2019
46
Antifibrotics in interstitial lung disease related to connective tissue diseases - a paradigm shift in treatment and outcome. 61
31280278 2019
47
Performance of the COPD Assessment Test in patients with connective tissue disease-associated interstitial lung disease. 61
30961943 2019
48
Multidisciplinary Evaluation in Patients with Lung Disease Associated with Connective Tissue Disease. 61
31137059 2019
49
A simplified lung ultrasound for the diagnosis of interstitial lung disease in connective tissue disease: a meta-analysis. 61
30975190 2019
50
Cellular senescence and senescence-associated secretory phenotype: comparison of idiopathic pulmonary fibrosis, connective tissue disease-associated interstitial lung disease, and chronic obstructive pulmonary disease. 61
31019774 2019

Variations for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Expression for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Search GEO for disease gene expression data for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease.

Pathways for Secondary Interstitial Lung Disease in Childhood and Adulthood...

GO Terms for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Sources for Secondary Interstitial Lung Disease in Childhood and Adulthood...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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