MCID: SCN068
MIFTS: 18

Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards integrated aliases for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

Name: Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease 58
Secondary Ild in Childhood and Adulthood Associated with a Connective Tissue Disease 58
Ctd-Ild 58

Classifications:

Orphanet: 58  
Rare respiratory diseases


External Ids:

Orphanet 58 ORPHA182104

Summaries for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards based summary : Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease, also known as secondary ild in childhood and adulthood associated with a connective tissue disease, is related to interstitial lung disease and connective tissue disease. The drugs Acetylcysteine and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and skin.

Related Diseases for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 interstitial lung disease 10.7
2 connective tissue disease 10.7
3 lung disease 10.7
4 scleroderma, familial progressive 10.5
5 myopathy 10.3

Graphical network of the top 20 diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:



Diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Symptoms & Phenotypes for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Drugs & Therapeutics for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Drugs for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcysteine Approved, Investigational Phase 2, Phase 3 616-91-1 12035
2 Anti-Infective Agents Phase 2, Phase 3
3 Antiviral Agents Phase 2, Phase 3
4 N-monoacetylcystine Phase 2, Phase 3
5 Free Radical Scavengers Phase 2, Phase 3
6 Antioxidants Phase 2, Phase 3
7 Respiratory System Agents Phase 2, Phase 3
8 Protective Agents Phase 2, Phase 3
9 Antidotes Phase 2, Phase 3
10 Expectorants Phase 2, Phase 3
11
Midazolam Approved, Illicit 59467-70-8 4192
12
Lidocaine Approved, Vet_approved 137-58-6 3676
13 Anesthetics
14 Pharmaceutical Solutions
15 Calamus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical Trial of Oral Medication for CTD-ILD Treatment Terminated NCT01424033 Phase 2, Phase 3 N-Acetylcysteine
2 Study of the Etiology and Immunological Pathogenesis in Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF) Unknown status NCT02509364
3 The Clinical Course of Interstitial Pneumonia With Autoimmune Features: an Observational, Prospective Cohort Study Recruiting NCT03950583
4 Incidence, Clinical Characteristics and Evaluation of Prognostic and Diagnostic Markers of Interstitial Pneumonia With Autoimmune Features (IPAF) - a Multicenter Prospective Study Not yet recruiting NCT03870828

Search NIH Clinical Center for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Genetic Tests for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Anatomical Context for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards organs/tissues related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

40
Lung, Testes, Skin, T Cells, B Cells

Publications for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Articles related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

(show top 50) (show all 138)
# Title Authors PMID Year
1
Association of ADAM17 Expression Levels in Patients with Interstitial Lung Disease. 61
31469350 2020
2
Therapeutic Options for the Treatment of Interstitial Lung Disease Related to Connective Tissue Diseases. A Narrative Review. 61
32028635 2020
3
Comparative analysis of connective tissue disease-associated interstitial lung disease and interstitial pneumonia with autoimmune features. 61
31758424 2020
4
The value of serum Krebs von den lungen-6 as a diagnostic marker in connective tissue disease associated with interstitial lung disease. 61
31915006 2020
5
Impact of a systematic evaluation of connective tissue disease on diagnosis approach in patients with interstitial lung diseases. 61
31977850 2020
6
Real-world experiences: Efficacy and tolerability of pirfenidone in clinical practice. 61
31999801 2020
7
Clinical significance of self-reported cough intensity and frequency in patients with interstitial lung disease: a cross-sectional study. 61
31842848 2019
8
Acute exacerbations of fibrosing interstitial lung disease associated with connective tissue diseases: a population-based study. 61
31727051 2019
9
Baseline characteristics and comorbidities in the CAnadian REgistry for Pulmonary Fibrosis. 61
31771541 2019
10
[Clinical value of myositis antibodies in patients with connective tissue disease-associated interstitial lung diseases]. 61
31594111 2019
11
Review: Serum biomarkers in idiopathic pulmonary fibrosis and systemic sclerosis associated interstitial lung disease - frontiers and horizons. 61
31153954 2019
12
Exploring the Ability of Electronic Nose Technology to Recognize Interstitial Lung Diseases (ILD) by Non-Invasive Breath Screening of Exhaled Volatile Compounds (VOC): A Pilot Study from the European IPF Registry (eurIPFreg) and Biobank. 61
31623141 2019
13
Demographic and clinical predictors of progression and mortality in connective tissue disease-associated interstitial lung disease: a retrospective cohort study. 61
31672127 2019
14
Long-term survival of lung transplantation for interstitial lung disease associated with connective tissue diseases: a study of 26 cases from a referral centre. 61
31694743 2019
15
[The diagnostic value of serum KL-6 in connective tissue disease associated interstitial lung disease]. 61
31694110 2019
16
[Expression and clinical significance of CCL18 in bronchoalveolar lavage fluid of connective tissue disease-associated interstitial lung disease]. 61
31607028 2019
17
Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 5. Connective Tissue Disease Associated Interstitial Lung Disease. 61
31172701 2019
18
Current and Emerging Drug Therapies for Connective Tissue Disease-Interstitial Lung Disease (CTD-ILD). 61
31399860 2019
19
Hyaluronic Acid-Decorated Liposomes as Innovative Targeted Delivery System for Lung Fibrotic Cells. 61
31509965 2019
20
Feasibility of low-dose CT with spectral shaping and third-generation iterative reconstruction in evaluating interstitial lung diseases associated with connective tissue disease: an intra-individual comparison study. 61
30737567 2019
21
Clinical features and outcome of acute exacerbation in connective tissue disease-associated interstitial lung disease: A single-center study from India. 61
31328423 2019
22
In vivo probe-based confocal laser endomicroscopy in chronic interstitial lung diseases: Specific descriptors and correlation with chest CT. 61
30811085 2019
23
Long-term clinical course and outcome of interstitial pneumonia with autoimmune features. 61
31387157 2019
24
Rituximab in connective tissue disease-associated interstitial lung disease. 61
31016581 2019
25
Connective tissue disease-associated interstitial lung disease and outcomes after hospitalization: A cohort study. 61
31176795 2019
26
Interstitial pneumonia with autoimmune features show better survival and less exacerbations compared to idiopathic pulmonary fibrosis. 61
31272428 2019
27
Impact of an interstitial lung disease service in the diagnosis and management of interstitial lung disease in Singapore. 61
31317200 2019
28
Comparison of clinical courses and mortality of connective tissue disease-associated interstitial pneumonias and chronic fibrosing idiopathic interstitial pneumonias. 61
30913371 2019
29
Lung Cancer development and mortality in interstitial lung disease with and without connective tissue diseases: a five-year Nationwide population-based study. 61
31182103 2019
30
Computed Tomography Honeycombing Identifies a Progressive Fibrotic Phenotype with Increased Mortality across Diverse Interstitial Lung Diseases. 61
30653927 2019
31
Telomere length and genetic variant associations with interstitial lung disease progression and survival. 61
30635297 2019
32
Antifibrotics in interstitial lung disease related to connective tissue diseases - a paradigm shift in treatment and outcome. 61
31280278 2019
33
Performance of the COPD Assessment Test in patients with connective tissue disease-associated interstitial lung disease. 61
30961943 2019
34
Multidisciplinary Evaluation in Patients with Lung Disease Associated with Connective Tissue Disease. 61
31137059 2019
35
A simplified lung ultrasound for the diagnosis of interstitial lung disease in connective tissue disease: a meta-analysis. 61
30975190 2019
36
Cellular senescence and senescence-associated secretory phenotype: comparison of idiopathic pulmonary fibrosis, connective tissue disease-associated interstitial lung disease, and chronic obstructive pulmonary disease. 61
31019774 2019
37
Evaluation of multiple-flows exhaled nitric oxide in idiopathic and non-idiopathic interstitial lung disease. 61
30690441 2019
38
Serum KL-6 levels reflect the severity of interstitial lung disease associated with connective tissue disease. 61
30764869 2019
39
Utility of Anti-DSF70 Antibodies to Predict Connective Tissue Disease in Patients Originally Presenting with Idiopathic Interstitial Pneumonia. 61
30928980 2019
40
Validation of the ILD-GAP Model and a Local Nomogram in a Singaporean Cohort. 61
31578022 2019
41
Connective Tissue Disease Associated Interstitial Lung Disease - An Acute Exacerbation In Emergency Room. 61
30868797 2019
42
Vitamin D deficiency in connective tissue disease-associated interstitial lung disease. 61
29846166 2018
43
Multidimensional improvement in connective tissue disease-associated interstitial lung disease: Two courses of pulse dose methylprednisolone followed by low-dose prednisone and tacrolimus. 61
30011421 2018
44
Rheumatological Assessment Is Important for Interstitial Lung Disease Diagnosis. 61
30111640 2018
45
Association between Pepsin in Bronchoalveolar Lavage Fluid and Prognosis of Chronic Fibrosing Interstitial Lung Disease. 61
30405002 2018
46
New treatment paradigms for connective tissue disease-associated interstitial lung disease. 61
30020142 2018
47
[What rheumatologists can learn from pneumologists]. 61
30006857 2018
48
Clinical significance of radiological pleuroparenchymal fibroelastosis pattern in interstitial lung disease patients registered for lung transplantation: a retrospective cohort study. 61
30165854 2018
49
Autoreactive T cells to citrullinated HSP90 are associated with interstitial lung disease in rheumatoid arthritis. 61
29968330 2018
50
Value of Serum Carbohydrate Antigen 19-9 and Carcinoembryonic Antigen in Evaluating Severity and Prognosis of Connective Tissue Disease-Associated Interstitial Lung Disease. 61
30207560 2018

Variations for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Expression for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Search GEO for disease gene expression data for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease.

Pathways for Secondary Interstitial Lung Disease in Childhood and Adulthood...

GO Terms for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Sources for Secondary Interstitial Lung Disease in Childhood and Adulthood...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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