MCID: SCN068
MIFTS: 18

Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards integrated aliases for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

Name: Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease 58
Secondary Ild in Childhood and Adulthood Associated with a Connective Tissue Disease 58
Ctd-Ild 58

Classifications:

Orphanet: 58  
Rare respiratory diseases


External Ids:

Orphanet 58 ORPHA182104

Summaries for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards based summary : Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease, also known as secondary ild in childhood and adulthood associated with a connective tissue disease, is related to interstitial lung disease and connective tissue disease. The drugs Acetylcysteine and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and skin.

Related Diseases for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 5, show less)
# Related Disease Score Top Affiliating Genes
1 interstitial lung disease 10.7
2 connective tissue disease 10.7
3 lung disease 10.7
4 scleroderma, familial progressive 10.5
5 myopathy 10.3

Graphical network of the top 20 diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:



Diseases related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Symptoms & Phenotypes for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Drugs & Therapeutics for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Drugs for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 15, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcysteine Approved, Investigational Phase 2, Phase 3 616-91-1 12035
2 Anti-Infective Agents Phase 2, Phase 3
3 Antiviral Agents Phase 2, Phase 3
4 N-monoacetylcystine Phase 2, Phase 3
5 Free Radical Scavengers Phase 2, Phase 3
6 Antioxidants Phase 2, Phase 3
7 Respiratory System Agents Phase 2, Phase 3
8 Protective Agents Phase 2, Phase 3
9 Antidotes Phase 2, Phase 3
10 Expectorants Phase 2, Phase 3
11
Midazolam Approved, Illicit 59467-70-8 4192
12
Lidocaine Approved, Vet_approved 137-58-6 3676
13 Anesthetics
14 Pharmaceutical Solutions
15 Calamus

Interventional clinical trials:

(showing 4, show less)
# Name Status NCT ID Phase Drugs
1 Clinical Trial of Oral Medication for CTD-ILD Treatment Terminated NCT01424033 Phase 2, Phase 3 N-Acetylcysteine
2 Study of the Etiology and Immunological Pathogenesis in Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF) Unknown status NCT02509364
3 The Clinical Course of Interstitial Pneumonia With Autoimmune Features: an Observational, Prospective Cohort Study Recruiting NCT03950583
4 Incidence, Clinical Characteristics and Evaluation of Prognostic and Diagnostic Markers of Interstitial Pneumonia With Autoimmune Features (IPAF) - a Multicenter Prospective Study Not yet recruiting NCT03870828

Search NIH Clinical Center for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease

Genetic Tests for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Anatomical Context for Secondary Interstitial Lung Disease in Childhood and Adulthood...

MalaCards organs/tissues related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

40
Lung, Testes, Skin, T Cells, B Cells

Publications for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Articles related to Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease:

(showing 138, show less)
# Title Authors PMID Year
1
Association of ADAM17 Expression Levels in Patients with Interstitial Lung Disease. 61
31469350 2020
2
Therapeutic Options for the Treatment of Interstitial Lung Disease Related to Connective Tissue Diseases. A Narrative Review. 61
32028635 2020
3
Comparative analysis of connective tissue disease-associated interstitial lung disease and interstitial pneumonia with autoimmune features. 61
31758424 2020
4
The value of serum Krebs von den lungen-6 as a diagnostic marker in connective tissue disease associated with interstitial lung disease. 61
31915006 2020
5
Impact of a systematic evaluation of connective tissue disease on diagnosis approach in patients with interstitial lung diseases. 61
31977850 2020
6
Real-world experiences: Efficacy and tolerability of pirfenidone in clinical practice. 61
31999801 2020
7
Clinical significance of self-reported cough intensity and frequency in patients with interstitial lung disease: a cross-sectional study. 61
31842848 2019
8
Acute exacerbations of fibrosing interstitial lung disease associated with connective tissue diseases: a population-based study. 61
31727051 2019
9
Baseline characteristics and comorbidities in the CAnadian REgistry for Pulmonary Fibrosis. 61
31771541 2019
10
[Clinical value of myositis antibodies in patients with connective tissue disease-associated interstitial lung diseases]. 61
31594111 2019
11
Review: Serum biomarkers in idiopathic pulmonary fibrosis and systemic sclerosis associated interstitial lung disease - frontiers and horizons. 61
31153954 2019
12
Exploring the Ability of Electronic Nose Technology to Recognize Interstitial Lung Diseases (ILD) by Non-Invasive Breath Screening of Exhaled Volatile Compounds (VOC): A Pilot Study from the European IPF Registry (eurIPFreg) and Biobank. 61
31623141 2019
13
Demographic and clinical predictors of progression and mortality in connective tissue disease-associated interstitial lung disease: a retrospective cohort study. 61
31672127 2019
14
Long-term survival of lung transplantation for interstitial lung disease associated with connective tissue diseases: a study of 26 cases from a referral centre. 61
31694743 2019
15
[The diagnostic value of serum KL-6 in connective tissue disease associated interstitial lung disease]. 61
31694110 2019
16
[Expression and clinical significance of CCL18 in bronchoalveolar lavage fluid of connective tissue disease-associated interstitial lung disease]. 61
31607028 2019
17
Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 5. Connective Tissue Disease Associated Interstitial Lung Disease. 61
31172701 2019
18
Current and Emerging Drug Therapies for Connective Tissue Disease-Interstitial Lung Disease (CTD-ILD). 61
31399860 2019
19
Hyaluronic Acid-Decorated Liposomes as Innovative Targeted Delivery System for Lung Fibrotic Cells. 61
31509965 2019
20
Feasibility of low-dose CT with spectral shaping and third-generation iterative reconstruction in evaluating interstitial lung diseases associated with connective tissue disease: an intra-individual comparison study. 61
30737567 2019
21
Clinical features and outcome of acute exacerbation in connective tissue disease-associated interstitial lung disease: A single-center study from India. 61
31328423 2019
22
In vivo probe-based confocal laser endomicroscopy in chronic interstitial lung diseases: Specific descriptors and correlation with chest CT. 61
30811085 2019
23
Long-term clinical course and outcome of interstitial pneumonia with autoimmune features. 61
31387157 2019
24
Rituximab in connective tissue disease-associated interstitial lung disease. 61
31016581 2019
25
Connective tissue disease-associated interstitial lung disease and outcomes after hospitalization: A cohort study. 61
31176795 2019
26
Interstitial pneumonia with autoimmune features show better survival and less exacerbations compared to idiopathic pulmonary fibrosis. 61
31272428 2019
27
Impact of an interstitial lung disease service in the diagnosis and management of interstitial lung disease in Singapore. 61
31317200 2019
28
Comparison of clinical courses and mortality of connective tissue disease-associated interstitial pneumonias and chronic fibrosing idiopathic interstitial pneumonias. 61
30913371 2019
29
Lung Cancer development and mortality in interstitial lung disease with and without connective tissue diseases: a five-year Nationwide population-based study. 61
31182103 2019
30
Computed Tomography Honeycombing Identifies a Progressive Fibrotic Phenotype with Increased Mortality across Diverse Interstitial Lung Diseases. 61
30653927 2019
31
Telomere length and genetic variant associations with interstitial lung disease progression and survival. 61
30635297 2019
32
Antifibrotics in interstitial lung disease related to connective tissue diseases - a paradigm shift in treatment and outcome. 61
31280278 2019
33
Performance of the COPD Assessment Test in patients with connective tissue disease-associated interstitial lung disease. 61
30961943 2019
34
Multidisciplinary Evaluation in Patients with Lung Disease Associated with Connective Tissue Disease. 61
31137059 2019
35
A simplified lung ultrasound for the diagnosis of interstitial lung disease in connective tissue disease: a meta-analysis. 61
30975190 2019
36
Cellular senescence and senescence-associated secretory phenotype: comparison of idiopathic pulmonary fibrosis, connective tissue disease-associated interstitial lung disease, and chronic obstructive pulmonary disease. 61
31019774 2019
37
Evaluation of multiple-flows exhaled nitric oxide in idiopathic and non-idiopathic interstitial lung disease. 61
30690441 2019
38
Serum KL-6 levels reflect the severity of interstitial lung disease associated with connective tissue disease. 61
30764869 2019
39
Utility of Anti-DSF70 Antibodies to Predict Connective Tissue Disease in Patients Originally Presenting with Idiopathic Interstitial Pneumonia. 61
30928980 2019
40
Validation of the ILD-GAP Model and a Local Nomogram in a Singaporean Cohort. 61
31578022 2019
41
Connective Tissue Disease Associated Interstitial Lung Disease - An Acute Exacerbation In Emergency Room. 61
30868797 2019
42
Vitamin D deficiency in connective tissue disease-associated interstitial lung disease. 61
29846166 2018
43
Multidimensional improvement in connective tissue disease-associated interstitial lung disease: Two courses of pulse dose methylprednisolone followed by low-dose prednisone and tacrolimus. 61
30011421 2018
44
Rheumatological Assessment Is Important for Interstitial Lung Disease Diagnosis. 61
30111640 2018
45
Association between Pepsin in Bronchoalveolar Lavage Fluid and Prognosis of Chronic Fibrosing Interstitial Lung Disease. 61
30405002 2018
46
New treatment paradigms for connective tissue disease-associated interstitial lung disease. 61
30020142 2018
47
[What rheumatologists can learn from pneumologists]. 61
30006857 2018
48
Clinical significance of radiological pleuroparenchymal fibroelastosis pattern in interstitial lung disease patients registered for lung transplantation: a retrospective cohort study. 61
30165854 2018
49
Autoreactive T cells to citrullinated HSP90 are associated with interstitial lung disease in rheumatoid arthritis. 61
29968330 2018
50
Value of Serum Carbohydrate Antigen 19-9 and Carcinoembryonic Antigen in Evaluating Severity and Prognosis of Connective Tissue Disease-Associated Interstitial Lung Disease. 61
30207560 2018
51
Performance of the St George's Respiratory Questionnaire in patients with connective tissue disease-associated interstitial lung disease. 61
29575410 2018
52
FOXP3 polymorphisms in interstitial lung disease among Chinese Han population: A genetic association study. 61
28508461 2018
53
Prevalence of lung cancer in patients with interstitial lung disease is higher than in those with chronic obstructive pulmonary disease. 61
29538197 2018
54
Comparison of short-term outcomes for connective tissue disease-related interstitial lung disease and idiopathic pulmonary fibrosis after lung transplantation. 61
29707304 2018
55
CT Features of the Usual Interstitial Pneumonia Pattern: Differentiating Connective Tissue Disease-Associated Interstitial Lung Disease From Idiopathic Pulmonary Fibrosis. 61
29140119 2018
56
Lung cancer in connective tissue disease-associated interstitial lung disease: clinical features and impact on outcomes. 61
29607151 2018
57
Interstitial lung disease in systemic autoimmune rheumatic diseases: a comprehensive review. 61
29202589 2018
58
Selection of glucocorticoid-sensitive patients in interstitial lung disease secondary to connective tissue diseases population by radiomics. 61
30349276 2018
59
Cyclophosphamide for connective tissue disease-associated interstitial lung disease. 61
29297205 2018
60
[Lung transplantation for connective tissue disease-associated interstitial lung disease recipient]. 61
29050128 2017
61
Pathologic Separation of Chronic Hypersensitivity Pneumonitis From Fibrotic Connective Tissue Disease-associated Interstitial Lung Disease. 61
28614213 2017
62
Usefulness of lung ultrasound B-lines in connective tissue disease-associated interstitial lung disease: a literature review. 61
28923086 2017
63
[Manifestations of the connective tissue associated interstitial lung disease under high resolution computed tomography]. 61
28872085 2017
64
Utility of autoimmune serology testing in the assessment of uncharacterized interstitial lung disease: a large retrospective cohort review. 61
28830432 2017
65
The evidence of benefits of exercise training in interstitial lung disease: a randomised controlled trial. 61
28213592 2017
66
Treatment of connective tissue disease-associated interstitial lung disease: the pulmonologist's point of view. 61
28704913 2017
67
Idiopathic Interstitial Pneumonia Associated With Autoantibodies: A Large Case Series Followed Over 1 Year. 61
28300570 2017
68
Recent advances in connective tissue disease related interstitial lung disease. 61
28544856 2017
69
Lesson of the month 2: Dry skin, yellow nails and breathlessness. 61
28765421 2017
70
Rituximab versus cyclophosphamide for the treatment of connective tissue disease-associated interstitial lung disease (RECITAL): study protocol for a randomised controlled trial. 61
28619061 2017
71
Variants of the ABCA3 gene might contribute to susceptibility to interstitial lung diseases in the Chinese population. 61
28642621 2017
72
Association of serum levels of laminin, type IV collagen, procollagen III N-terminal peptide, and hyaluronic acid with the progression of interstitial lung disease. 61
28471958 2017
73
Role of Autoantibodies in the Diagnosis of Connective-Tissue Disease ILD (CTD-ILD) and Interstitial Pneumonia with Autoimmune Features (IPAF). 61
28471413 2017
74
Interstitial Lung Disease in the Elderly. 61
27865876 2017
75
The evaluation of clinical usefulness of transbrochoscopic lung biopsy in undefined interstitial lung diseases: a retrospective study. 61
25919041 2017
76
Interstitial Lung Disease in India. Results of a Prospective Registry. 61
27684041 2017
77
An analysis of the clinical features of lung cancer in patients with connective tissue diseases. 61
28274531 2017
78
[Clinical significance of hypersensitive C-reactive protein, fribrinogen and D-dimmer in connective tissue disease-related interstitial lung disease]. 61
28377364 2017
79
The correlation between miR-200c and the severity of interstitial lung disease associated with different connective tissue diseases. 61
27309544 2017
80
Lung cancer development in patients with connective tissue disease-related interstitial lung disease: A retrospective observational study. 61
27977621 2016
81
Azathioprine response in patients with fibrotic connective tissue disease-associated interstitial lung disease. 61
27888985 2016
82
Evaluation of computer-based computer tomography stratification against outcome models in connective tissue disease-related interstitial lung disease: a patient outcome study. 61
27876024 2016
83
Rituximab in autoimmune connective tissue disease-associated interstitial lung disease. 61
27060110 2016
84
Characterisation of patients with interstitial pneumonia with autoimmune features. 61
27103387 2016
85
Mean pulmonary arterial pressure as a prognostic indicator in connective tissue disease associated with interstitial lung disease: a retrospective cohort study. 61
27094018 2016
86
Association of serum KL-6 levels with interstitial lung disease in patients with connective tissue disease: a cross-sectional study. 61
26758437 2016
87
Benefit of adjunctive tacrolimus in connective tissue disease-interstitial lung disease. 61
26762710 2016
88
Management of interstitial lung disease associated with connective tissue disease. 61
26912511 2016
89
[The expression and clinical role of KL-6 in serum and BALF of patients with different diffuse interstitial lung diseases]. 61
26879611 2016
90
Aberrant expression of cytokine interleukin 9 along with interleukin 4 and interferon γ in connective tissue disease-associated interstitial lung disease: association with severity of pulmonary fibrosis. 61
26925124 2016
91
Connective tissue disease-related interstitial lung disease. 61
27421215 2016
92
Current and emerging treatment options for interstitial lung disease in patients with rheumatic disease. 61
26752397 2016
93
Increased Expression of CC16 in Patients with Idiopathic Pulmonary Fibrosis. 61
27977812 2016
94
Clinical Characteristics of Connective Tissue Disease-Associated Interstitial Lung Disease in 1,044 Chinese Patients. 61
26447566 2016
95
Rituximab for the treatment of connective tissue disease-associated interstitial lung disease. 61
26847096 2016
96
Diagnostic accuracy of lung ultrasound for interstitial lung disease in patients with connective tissue diseases: a meta-analysis. 61
26812366 2016
97
[Randomized control multi-center clinical study of mycophenolate mofetil and cyclophosphamide in the treatment of connective tissue disease related interstitial lung disease]. 61
26849923 2015
98
Connective Tissue Disease-associated Interstitial Lung Diseases (CTD-ILD) - Report from OMERACT CTD-ILD Working Group. 61
25729034 2015
99
Connective Tissue Disease-Associated Interstitial Lung Disease: A Focused Review. 61
24371251 2015
100
Serum B cell-activating factor (BAFF) level in connective tissue disease associated interstitial lung disease. 61
26424433 2015
101
Assessment and management of connective tissue disease-associated interstitial lung disease. 61
26237351 2015
102
Patient Perspectives in OMERACT Provide an Anchor for Future Metric Development and Improved Approaches to Healthcare Delivery in Connective Tissue Disease Related Interstitial Lung Disease (CTD-ILD). 61
26568747 2015
103
A meta-analysis examining the association between the MUC5B rs35705950 T/G polymorphism and susceptibility to idiopathic pulmonary fibrosis. 61
25926289 2015
104
Management of connective tissue disease-associated interstitial lung disease. 61
25836643 2015
105
Determining respiratory impairment in connective tissue disease-associated interstitial lung disease. 61
25836638 2015
106
The role of nailfold capillaroscopy in interstitial lung diseases - can it differentiate idiopathic cases from collagen tissue disease associated interstitial lung diseases? 61
25849052 2015
107
Predictors of mortality in patients with interstitial lung disease treated with corticosteroids: results from a cohort study. 61
25474431 2014
108
Clinical significance of mTOR, ZEB1, ROCK1 expression in lung tissues of pulmonary fibrosis patients. 61
25358403 2014
109
Current approach to connective tissue disease-associated interstitial lung disease. 61
25022317 2014
110
Prevalence of venous thromboembolic events and diagnostic performance of the wells score and revised geneva scores for pulmonary embolism in patients with interstitial lung disease: a prospective study. 61
24685075 2014
111
GM-CSF but not IL-17 is critical for the development of severe interstitial lung disease in SKG mice. 61
24951817 2014
112
Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials. 61
24368713 2014
113
Reconciling healthcare professional and patient perspectives in the development of disease activity and response criteria in connective tissue disease-related interstitial lung diseases. 61
24488412 2014
114
Pulmonary pathology in connective tissue disease. 61
24668535 2014
115
Biomarkers in connective tissue disease-associated interstitial lung disease. 61
24668534 2014
116
Can exhaled nitric oxide differentiate causes of pulmonary fibrosis? 61
24011803 2013
117
The diagnosis efficacy and safety of video-assisted thoracoscopy surgery (VATS) in undefined interstitial lung diseases: a retrospective study. 61
23825760 2013
118
Mycophenolate mofetil improves lung function in connective tissue disease-associated interstitial lung disease. 61
23457378 2013
119
Diagnosis and treatment of connective tissue disease-associated interstitial lung disease. 61
23460159 2013
120
Interstitial lung diseases in Saudi Arabia: A single-center study. 61
23440334 2013
121
Comparison of characteristics of connective tissue disease-associated interstitial lung diseases, undifferentiated connective tissue disease-associated interstitial lung diseases, and idiopathic pulmonary fibrosis in Chinese Han population: a retrospective study. 61
24171031 2013
122
Severe interstitial lung disease in connective tissue disease: rituximab as rescue therapy. 61
22282550 2012
123
Connective Tissue Disease-associated Interstitial Lung Disease: A review. 61
23125954 2012
124
Interstitial lung disease in connective tissue disorders. 61
22901890 2012
125
Interstitial lung disease in the connective tissue diseases. 61
22365251 2012
126
[Interstitial lung disease associated with connective tissue diseases: diagnosis and treatment approaches]. 61
23289473 2012
127
Autoimmune-featured interstitial lung disease: a distinct entity. 61
21565966 2011
128
Developing disease activity and response criteria in connective tissue disease-related interstitial lung disease. 61
21724725 2011
129
An analysis of connective tissue disease-associated interstitial lung disease at a US Tertiary Care Center: better survival in patients with systemic sclerosis. 61
21285162 2011
130
The impact of rheumatological evaluation in the management of patients with interstitial lung disease. 61
20685802 2011
131
Vitamin D deficiency and reduced lung function in connective tissue-associated interstitial lung diseases. 61
20688927 2011
132
Review series: Aspects of interstitial lung disease: connective tissue disease-associated interstitial lung disease: how does it differ from IPF? How should the clinical approach differ? 61
21339375 2011
133
Assessing dyspnea and its impact on patients with connective tissue disease-related interstitial lung disease. 61
20471238 2010
134
Development of Clinical Trial Assessments for the Study of Interstitial Lung Disease in Patients who have Connective Tissue Diseases-Methodological Considerations. 61
20676224 2010
135
Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management. 61
20735863 2010
136
Experience of mycophenolate mofetil in 10 patients with autoimmune-related interstitial lung disease demonstrates promising effects. 61
19295413 2009
137
Mycophenolate mofetil is safe, well tolerated, and preserves lung function in patients with connective tissue disease-related interstitial lung disease. 61
16840379 2006
138
Comparison of disease progression and mortality of connective tissue disease-related interstitial lung disease and idiopathic interstitial pneumonia. 61
16082627 2005

Variations for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Expression for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Search GEO for disease gene expression data for Secondary Interstitial Lung Disease in Childhood and Adulthood Associated with a Connective Tissue Disease.

Pathways for Secondary Interstitial Lung Disease in Childhood and Adulthood...

GO Terms for Secondary Interstitial Lung Disease in Childhood and Adulthood...

Sources for Secondary Interstitial Lung Disease in Childhood and Adulthood...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....