MCID: SCN048
MIFTS: 22

Secondary Syringomyelia

Categories: Fetal diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Secondary Syringomyelia

Summaries for Secondary Syringomyelia

MalaCards based summary : Secondary Syringomyelia is related to syringomyelia, noncommunicating isolated and syringomyelia. Affiliated tissues include spinal cord and bone, and related phenotypes are syringomyelia and hyperintensity of mri t2 signal of the spinal cord

Related Diseases for Secondary Syringomyelia

Diseases in the Syringomyelia family:

Familial Syringomyelia Secondary Syringomyelia
Primary Syringomyelia

Diseases related to Secondary Syringomyelia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
# Related Disease Score Top Affiliating Genes
1 syringomyelia, noncommunicating isolated 10.4
2 syringomyelia 10.4
3 spinal arachnoiditis 10.0
4 meningioma, radiation-induced 10.0
5 meningioma, familial 10.0
6 spinal meningioma 10.0
7 arachnoiditis 10.0
8 secretory meningioma 10.0
9 lymphoplasmacyte-rich meningioma 10.0
10 aneurysm 10.0
11 multiple sclerosis 9.8
12 fibrosis of extraocular muscles, congenital, 1 9.8
13 hydrocephalus 9.8
14 telangiectasis 9.8
15 astrocytoma 9.8
16 foramen magnum meningioma 9.8
17 benign ependymoma 9.8
18 cellular ependymoma 9.8
19 chiari malformation 9.8
20 spastic paraparesis 9.8
21 syringobulbia 9.8

Graphical network of the top 20 diseases related to Secondary Syringomyelia:



Diseases related to Secondary Syringomyelia

Symptoms & Phenotypes for Secondary Syringomyelia

Human phenotypes related to Secondary Syringomyelia:

58 31 (show all 26)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 syringomyelia 58 31 obligate (100%) Obligate (100%) HP:0003396
2 hyperintensity of mri t2 signal of the spinal cord 58 31 hallmark (90%) Very frequent (99-80%) HP:0040272
3 cranial nerve paralysis 58 31 frequent (33%) Frequent (79-30%) HP:0006824
4 back pain 58 31 frequent (33%) Frequent (79-30%) HP:0003418
5 paresthesia 58 31 frequent (33%) Frequent (79-30%) HP:0003401
6 difficulty walking 58 31 frequent (33%) Frequent (79-30%) HP:0002355
7 fatigable weakness 58 31 frequent (33%) Frequent (79-30%) HP:0003473
8 increased csf protein 58 31 frequent (33%) Frequent (79-30%) HP:0002922
9 paraplegia 58 31 frequent (33%) Frequent (79-30%) HP:0010550
10 sensory ataxia 58 31 frequent (33%) Frequent (79-30%) HP:0010871
11 csf pleocytosis 58 31 frequent (33%) Frequent (79-30%) HP:0012229
12 facial paralysis 58 31 frequent (33%) Frequent (79-30%) HP:0007209
13 decreased taste sensation 58 31 frequent (33%) Frequent (79-30%) HP:0000224
14 paroxysmal vertigo 58 31 frequent (33%) Frequent (79-30%) HP:0010532
15 nystagmus 58 31 occasional (7.5%) Occasional (29-5%) HP:0000639
16 seizures 58 31 occasional (7.5%) Occasional (29-5%) HP:0001250
17 progressive cerebellar ataxia 58 31 occasional (7.5%) Occasional (29-5%) HP:0002073
18 blurred vision 58 31 occasional (7.5%) Occasional (29-5%) HP:0000622
19 meningioma 58 31 occasional (7.5%) Occasional (29-5%) HP:0002858
20 dysuria 58 31 occasional (7.5%) Occasional (29-5%) HP:0100518
21 distal sensory loss of all modalities 58 31 occasional (7.5%) Occasional (29-5%) HP:0006984
22 bulbar palsy 58 31 occasional (7.5%) Occasional (29-5%) HP:0001283
23 pseudobulbar paralysis 58 31 occasional (7.5%) Occasional (29-5%) HP:0007024
24 cns demyelination 58 31 occasional (7.5%) Occasional (29-5%) HP:0007305
25 dysphonia 58 Frequent (79-30%)
26 sensory impairment 58 Frequent (79-30%)

Drugs & Therapeutics for Secondary Syringomyelia

Search Clinical Trials , NIH Clinical Center for Secondary Syringomyelia

Genetic Tests for Secondary Syringomyelia

Anatomical Context for Secondary Syringomyelia

MalaCards organs/tissues related to Secondary Syringomyelia:

40
Spinal Cord, Bone

Publications for Secondary Syringomyelia

Articles related to Secondary Syringomyelia:

(show all 32)
# Title Authors PMID Year
1
Facial changes related to brachycephaly in Cavalier King Charles Spaniels with Chiari-like malformation associated pain and secondary syringomyelia. 61
31691386 2019
2
Using machine learning to understand neuromorphological change and image-based biomarker identification in Cavalier King Charles Spaniels with Chiari-like malformation-associated pain and syringomyelia. 61
31552689 2019
3
Pilot study of head conformation changes over time in the Cavalier King Charles spaniel breed. 61
30635451 2019
4
Lipomeningocele associated with diplomyelia in a dog. 61
30541173 2018
5
Morphogenesis of Canine Chiari Malformation and Secondary Syringomyelia: Disorders of Cerebrospinal Fluid Circulation. 61
30101146 2018
6
Use of Morphometric Mapping to Characterise Symptomatic Chiari-Like Malformation, Secondary Syringomyelia and Associated Brachycephaly in the Cavalier King Charles Spaniel. 61
28122014 2017
7
Longitudinal Study of the Relationship among Craniocervical Morphology, Clinical Progression, and Syringomyelia in a Cohort of Cavalier King Charles Spaniels. 61
27311874 2016
8
Syringomyelia following surgery for a spontaneous spinal subdural hematoma in a 13-year-old girl with congenital von Willebrand disease: case report and literature review. 61
26277360 2016
9
Familial adhesive arachnoiditis associated with syringomyelia. 61
24481329 2014
10
[Case of rapidly progressive syringomyelia due to a spinal hemangioblastoma]. 61
25087558 2014
11
Quantitative trait loci (QTL) study identifies novel genomic regions associated to Chiari-like malformation in Griffon Bruxellois dogs. 61
24740420 2014
12
Syringomyelia regression after shunting of a trapped fourth ventricle. 61
24765489 2013
13
Symptomatic syringomyelia secondary to clinically obscure infratentorial tumour. 61
16698611 2006
14
Spinal cord compression and bilateral sensory neural hearing loss: an unusual manifestation of neurocysticercosis. 61
15560705 2004
15
Inheritance of occipital bone hypoplasia (Chiari type I malformation) in Cavalier King Charles Spaniels. 61
15515584 2004
16
Successful removal after radiotherapy and vascular embolization in a huge tentorial epithelioid hemangioendothelioma: a case report. 61
15218955 2004
17
[Evoked potentials in Chiari-malformation type I with syringomyelia--a case history]. 61
12929016 2003
18
Secondary holocord syringomyelia with spinal hemangioblastoma: a report of two cases. 61
12865521 2003
19
Secondary syringomyelia disappearing after removal of tentorial meningioma. 61
12181709 2002
20
Multiple sclerosis with secondary syringomyelia. An autopsy report. 61
11239955 2001
21
Arachnoid telangiectasia causing meningeal fibrosis and secondary syringomyelia. 61
11303664 2001
22
Familial spinal arachnoiditis with secondary syringomyelia: clinical studies and MRI findings. 61
10967183 2000
23
Secondary syringomyelia due to intramedullary spinal cord metastasis. Case report and review of literature. 61
9391544 1997
24
Secondary syringomyelia. 61
8469357 1993
25
Advances in diagnosis and treatment of spinal hemangioblastomas. 61
8272209 1993
26
[A case of spinal arteriovenous malformation associated with syringomyelia extended over the entire spinal cord that presented mainly as spastic paraparesis]. 61
1934782 1991
27
Holocord astrocytoma--case report. 61
1710327 1990
28
[Clinically manifest or silent primary and secondary syringomyelia. The magnetic resonance findings]. 61
2377746 1990
29
Central spinal cord injury: magnetic resonance imaging confirmation and operative considerations. 61
3352884 1988
30
[Pathogenesis and the treatment of secondary syringomyelia]. 61
3828149 1987
31
Secondary Syringomyelia. ? Vertebral Aneurysm. 61
20915453 1937
32
Secondary Syringomyelia. ? Vertebral Aneurysm. 61
19991056 1937

Variations for Secondary Syringomyelia

Expression for Secondary Syringomyelia

Search GEO for disease gene expression data for Secondary Syringomyelia.

Pathways for Secondary Syringomyelia

GO Terms for Secondary Syringomyelia

Sources for Secondary Syringomyelia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....